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Excretion in Medical News

Immunoglobulin Can Predict Some Diabetic Complications

... Increased excretion of IgM foretells serious cardiovascular issues: ... to investigate the impact of increased urine IgM excretion on DN disease progression in type 1 diabetes ... "We found that those with increased urinary IgM excretion had a higher mortality from cardiovascular causes ...

Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis

... (PAGN). PAGN mediates waste nitrogen excretion and ammonia removal. The extent of plasma ... given fasting on day 1 or with a meal on day 8. excretion of the main metabolite PAGN was similar between ... of the administered dose, and the mean total excretion of PAGN after the last dose in the study (day 15) ...

FDA Approves SAMSCA(TM) (tolvaptan), the First and Only Oral Vasopressin Antagonist to Treat Patients With Clinically Significant Hypervolemic and Euvolemic Hyponatremia

... at the V2-receptor, SAMSCA increases the excretion of free water, while the excretion of sodium and other electrolytes is not directly ... without causing a significant change in urine excretion of electrolytes, which is good news for patients ...

New Almond Study Finds Chewing is More Than Meets the Mouth: Thorough Chewing May Influence Feelings of Fullness

... and collected stool samples to measure lipid excretion after almond consumption. Additionally, ... fat, available for absorption, with lipid excretion significantly higher after 10 chews than after 25 ... than after 10 chews (both P <0.05). Fecal fat excretion was significantly higher after 10 chews than ...

Vitamin B1 could reverse early-stage kidney disease in diabetes patients

... of kidney disease is assessed by a high excretion rate of the protein albumin from the body in the ... doses of thiamine can dramatically decrease the excretion of albumin and reverse early stage kidney disease ... day for three months reduced the rate of albumin excretion in type 2 diabetes patients. The ...

Study identifies causes of bone loss in breast cancer survivors

... including vitamin D deficiency, excessive calcium excretion in urine and an overactive parathyroid gland. ... Another cause of osteoporosis, excessive calcium excretion in urine, was found in 16 percent of cancer ... doses of vitamin D supplements. Excessive calcium excretion can be treated with a "water pill" that's also ...

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Excretion in Medical Technology

Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594

... of uric acid ex vivo and increases uric acid excretion in animal models. These effects are believed to ... RDEA806 in healthy volunteers, increased urinary excretion of uric acid was observed in the first 24 hours ... to be under-excretors of uric acid, so increasing excretion may provide the most physiologically appropriate ...

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

... dose accompanied by a significant increase (>100-fold) in glucose excretion in the urine in multiple species including monkeys Secondary ... activity of the drug by measuring the effect of ISIS-SGLT2Rx on glucose excretion in urine. We are excited to continue to move this drug forward through ...

Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference

... re-absorption in the kidney. Decreasing SGLT2 function promotes glucose excretion to help reduce blood sugar levels, making it an attractive target for the ... target mRNA levels in several animal species, increased urinary glucose excretion and consequently lowered blood glucose levels and HbA1c (in hyperglycemic ...

Keryx Biopharmaceuticals Completes SUN-MICRO Phase 3 Pivotal Trial

... of this chemical family have been shown to decrease pathological albumin excretion in diabetic nephropathy in humans. Some of the members of this chemical ... Phase II studies, that sulodexide can reduce urinary protein excretion in patients with diabetic nephropathy. ABOUT KERYX BIOPHARMACEUTICALS, ...

Sulodexide Data Safety Monitoring Committee Completes Additional Review of Phase 3 Study Data

... of this chemical family have been shown to decrease pathological albumin excretion in diabetic nephropathy in humans. Some of the members of this chemical ... Phase II studies, that Sulonex can reduce urinary protein excretion in patients with diabetic nephropathy. Sulonex is in a pivotal Phase 3 ...

Covance Announces Integrated Radiolabeled Clinical Pharmacology Studies

... Drug Administration (FDA) guidance on Metabolites in Safety Testing (MIST). Recent MIST guidance requires earlier human absorption, metabolism and excretion (AME) testing in support of Investigative New Drug/Clinical Trial Application (IND/CTA) submissions. "Integrated human AME services are ...

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Excretion in Medical Products

MM-PTH RIA Test

Description:... secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal ...
Company:Diagnostic Systems Laboratories, Inc.

C-PTH RIA Test

Description:... secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal ...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH IRMA Test

Description:... secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal ...
Company:Diagnostic Systems Laboratories, Inc.

I-PTH ELISA Test

Description:... secreted in response to decreased extracellular calcium concentrations. PTH prevents hypocalcemia by enhancing bone resorption and decreasing calcium excretion by the kidney. Following release into the circulation, intact PTH is rapidly degraded into 4 fragments: N-terminal (residues 1-34), C-terminal ...
Company:Diagnostic Systems Laboratories, Inc.

Unconjugated Estriol, Ultra-Sensitive EIA Test

Description:... magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact maternal-placental-fetal circulation and functional fetal ...
Company:Diagnostic Systems Laboratories, Inc.

Unconjugated Estriol, Ultra-Sensitive RIA Test

Description:... magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact maternal-placental-fetal circulation and functional fetal ...
Company:Diagnostic Systems Laboratories, Inc.

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Excretion in Medical Dictionary

Absorption

... fat -soluble vitamins A, D, E, and K. PHARMACOKINETICS: The processes (in a living organ ism) of absorption , distribution, metabolism , and excretion of a drug or vaccine . Another form of jaundice , found in about two out of every 100 breast -fed babies, is caused by a component in breast ...

Acute porphyria

... ACUTE PORPHYRIA - A group of metabolic disorders that result from a disturbance in porphyrin metabolism , causing increased formation and excretion of porphyrin or its precursors. Acute porphyria People with acute porphyria experience episodes of pain and disruption of the nervous system ...

Aldolase

... reactions. Aldolase helps muscle turn sugar into energy. Aldolase Aldosterone Aldosterone - Urine (24-Hour Urinary Aldosterone excretion Rate) Alertness - Decreased ( Consciousness - Decreased) Aliseum (Diazepam Overdose) ... ...

Aldosterone

... congestive heart failure such as spironolactone or eplerenone ... Aldolase Aldosterone Aldosterone - Urine (24-Hour Urinary Aldosterone excretion Rate) Alertness - Decreased ( Consciousness - Decreased) Aliseum (Diazepam Overdose) ... In this condition, a tumor in the ad renal gland , ...

Aminoaciduria

... Aminoaciduria Definition: The aminoaciduria test screens for increased levels of amino acid excretion in the urine that indicates possible inborn errors of metabolism caused by a specific enzyme deficiency . Aminoaciduria The abnormal ...

Canavan disease

... Canavan disease is caused by a deficiency of the enzyme aspartoacylase. This leads to increased excretion of a substance (its substrate) called N-acetyl aspartic acid (NAA) in the urine . Canavan disease of the brain Congenital neutropenia , a ...

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Excretion in Biological News

Researchers may have found why women have an edge on salt-sensitive hypertension

... compared to males and actually increases sodium excretion without increasing blood pressure. Researchers ... ETB receptor increased urine output and sodium excretion in both sexes, suggesting that it was not a ... look at how ETA receptor blockers impact sodium excretion in humans. ...

Blood pressure response to daily stress provides clues for better hypertension treatment

... B receptor plays a critical role in promoting excretion of acute and chronic salt loads by activating the ... which blocks this hormone, and see if sodium excretion improves. He'll also see how a high-fat diet and ... young study participants with impaired sodium excretion will take a drug to block the powerful blood ...

Athletes' 'sweat and tears' linked to asthma

... EIA. Researchers also found a correlation between the net sweat fluid excretion and net sweat sodium excretion, with sodium excretion rates being higher in subjects who were unresponsive to methacholine ...

Taking the fight against cancer to heart

... in the atrium of the heart and stimulates the production of urine and the excretion of sodium. Vesely later discovered three more hormones that are ... lowers blood pressure Kaliuretic peptide which increases potassium excretion The hormones, called peptide hormones because they are composed of ...

Diabetics on high-fiber diets might need extra calcium, report UT Southwestern researchers

... grapefruit, papaya, okra, winter and zucchini squash, granola and oatmeal. No supplements were used. "The reduction of urinary calcium excretion on high-fiber diets tells us that the amount of dietary fiber has a direct impact on calcium absorption," Dr. Garg said. "In other words, the ...

Common gene variants increase risk of hypertension, may lead to new therapies

... involved in the production of atrial and B-type natriuretic peptides (ANP and BNP) proteins known to relax blood vessels and to be involved in the excretion of dietary sodium. Animals in which both copies of NPPA have been knocked out are hypertensive, and even those with a single functional copy will ...

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Excretion in Biological Technology

Isis Initiates Phase 1 Clinical Trial of SGLT2 Antisense Drug

... kidney. Decreasing SGLT2 levels promotes glucose excretion in the urine and reduces blood sugar levels, ... activity by evaluating its effect on glucose excretion in urine. "In several preclinical models, we ... and decreasing SGLT2 function promotes glucose excretion to help reduce blood sugar levels, making it an ...

Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology

... of uric acid ex vivo and increases uric acid excretion in animal models. These findings suggest that ... RDEA806 in healthy volunteers, increased urinary excretion of uric acid was observed in the first 24 hours ... to be under-excretors of uric acid, so increasing excretion may provide the most physiologically appropriate ...

Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure

... decrease in blood pressure and increase in cGMP levels, diuresis (kidney excretion of water) and natriuresis (kidney excretion of sodium). The data from this first study has been accepted for ...

HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point-of-Care Test for Microalbuminuria, a Kidney and Cardiovascular Disease Risk Marker

... by the presence of albumin, a protein, excreted in urine. As the albumin excretion increases, so does the risk of CKD or cardiovascular disease onset and ... HemoCue Albumin 201 System, physicians may monitor changes in microalbumin excretion in a patient over time. A study in the American Journal of Nephrology ...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

... examined the relationship between CLDN14 and the metabolism of calcium. The results suggest that the SNP may be contributing to increased calcium excretion in urine, a major risk factor for kidney stones and also a sign of bone loss. "This is an exciting finding because it uncovers a highly ...

First H1N1 Swine Flu Vaccine, Replikins-Based, Is Ready Now for Testing Worldwide

... H5N1 avian flu, produced in a 7-day period, was recently tested at the University of Georgia and shown to block H5N1 virus entry, replication, and excretion in chickens (paper submitted for publication). Institutions requesting Replikins' H1N1 vaccine for testing should contact John McKenney at ...
Excretion in Biological Definition

Metabolism

... Nitrogen metabolism includes the pathways for turnover and excretion of nitrogen in organisms as well as the biological processes of the biogeochemical nitrogen cycle : Urea cycle , important for excretion of nitrogen as urea. Biological nitrogen fixation Nitrogen ...

Skin

... . Skin is used for insulation , vitamin D production, sensation , and excretion (through sweat ). Skin on creatures regularly subjected to sunlight ... Excretion: The concentration of urea is 1/130th than that of urine. excretion by sweating is at most a secondary function to temperature regulation. ...

Albumin

... Buffers pH Causes of albumin deficiency: Cirrhosis of the liver (most commonly) Decreased production (as in starvation) Excess excretion by the kidneys (as in nephrotic syndrome ) Excess loss in bowel (protein losing enteropathy) Mutation causing albuminemia (very rare) ...

Excretion

... excretion is the biological process by which an organism separates waste products from its body. The waste products are then usually expelled from the body ...

Hormone

... control system, generally by negative feedback . Homeostatic regulation of hormones depends, apart from production, on the metabolism and excretion of hormones. Hormone secretion can be stimulated and inhibited by: Other hormones ( stimulating or releasing -hormones) Plasma ...

Kidney

... bladder . The ureter carries urine from the kidneys to the bladder by means of peristalsis . Renal functions Renal functions include the excretion of waste material from the bloodstream, secretion of hormones - particularly erythropoietin and renin and maintaining serum electrolyte, ...

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Excretion in Biological Dictionary

Excretion

... excretion is the process of eliminating waste products of ... nitrogenous by-products of metabolism. Through excretion organisms control osmotic pressure—the balance ... from ... The biliary system contributes to excretion to the degree that drug is not ... With aging, ...

Osmoregulation

... that serve also for the ... Thus, urination is a mechanism of both waste excretion and osmoregulation . ... Definition of osmoregulation from the ... information on Osmoregulation from Biology-Online.org dictionary. ... excretion and Osmoregulation in Phylum Platyhelminthes? ... This page ...

Deamination

... places at Britannica. Assorted References amino acid degradation ( in excretion (biology): Products of excretion ) ... is used as a source of energy to drive other vital processes. ...

Homeostasis

... ... Homeostasis (a Greek term meaning same state), is the maintenance of constant ... Mechanisms of Sodium Homeostasis : Sodium and Water excretion in Mammals; ... ...

Coelom

... the identifying physiological characteristics of Mollusks, identify ... coelom . soft body. head-footvisceral massmantle. radula. Digestion and excretion ... In the Amphioxus the coelom is developed in the embryo as a series of bilateral ... In the intestinal region the coelom is only present ...

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