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Estrogen in Medical News

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

... approval for Ophena(TM) , a new SERM (selective estrogen receptor modulator) for the treatment of the ... pain (dyspareunia) and irritation. Declining estrogen levels during menopause can cause tissues of the ... program. Fispemifene is a new selective estrogen receptor antagonist that is in Phase 2 studies as ...

Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published

... you should know about PREMARIN Vaginal Cream (an estrogen mixture)? Estrogens may increase the ... and Vaginal Atrophy Women produce less estrogen after menopause. When estrogen levels begin dropping, vaginal walls become ...

Migraines Linked to Reduced Breast Cancer Risk

... Researchers suspect estrogen levels play a part in the connection ... triggers for migraine are also things that reduce estrogen levels," he said. It's well-known that many ... that women who have migraines may have drops in estrogen levels that trigger migraines. And women who have ...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

... the biological effects of a novel membrane estrogen receptor, a finding that has potential ... transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is ...

New Data: Efficacy and Responder Analyses of Divigel(R) (estradiol gel) 0.1 percent for the Treatment of Menopause

... women the lowest effective FDA-approved dose of estrogen therapy for MSVMS in post-menopausal women and ... treatment of MSVMS associated with menopause. The estrogen in Divigel(R) is derived from plant sources and is identical to the primary estrogen produced by a woman's ovaries before menopause. ...

Defeating nicotine's double role in lung cancer

... asked if nicotine may be to lung cancer what estrogen is to breast cancer. Eliot R. Spindel, M.D., ... Oregon Health & Science University, stated that estrogen can stimulate the development of breast cancer ... of breast cancer appears to be decreasing as estrogen hormone replacement therapy is being used less ...

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Estrogen in Medical Technology

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

... are risks and a potential loss of benefit to estrogen therapy in women who have been postmenopausal for ... research continues to underscore the theory that estrogen may be cardio-protective if administered close to ... (PEPI) trial compared conjugated equine estrogen (CEE) with three different CEE-progestin ...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

... dermatologists argue that scientific studies of estrogen do not show definitive improvements for skin ... mixed results when examining whether or not estrogen improves the appearance of the skin and why ... their use and the known risks of prolonged estrogen therapy -- including an increased risk of breast ...

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

... by Wyeth as a TSEC (tissue selective estrogen complex) as it combines a selective estrogen receptor modulator (SERM) with conjugated ... in Menopausal Therapy with a Tissue Selective estrogen Complex (TSEC) Containing Bazedoxifene/Conjugated ...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

... in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published ... endometrial cancer in animal models, unlike many estrogen therapies. This suggests that these plant-derived ... drugs that mediate their effects through estrogen receptors, which are responsible for many ...

UNT Health Science Center's Groundbreaking Research Applied to Protecting Brain After Traumatic Injury

... Center at Fort Worth have determined that rapid estrogen administration can protect the brain following ... animal studies of the protective effects of rapid estrogen treatment to human patients with severe traumatic ... "Our animal research has demonstrated that rapid estrogen intervention protects the brain following injury, ...

Investigational Cancer Drug BSI-201 Showed Clinical Benefit in 62% of Patients with Triple-Negative Metastatic Breast Cancer and Significantly Prolonged Survival

... TNBC, defined as tumors lacking expression of estrogen and progesterone receptors and without ... tumors are routinely tested for the presence of estrogen and progesterone receptors and for the ... receptors; for example, tamoxifen for estrogen receptor and trastuzumab (Herceptin(r)) for HER2. ...

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Estrogen in Medical Products

Estradiol, Ultra-Sensitive RIA Test

Description:... (E2) is the most potent, naturally secreted estrogen and is the major estrogen produced by the ovary [1]. In the ovary, ... [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and ...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol RIA Test

Description:... (E2) is the most potent, naturally secreted estrogen and is the major estrogen produced by the ovary [1]. In the ovary, ... [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and ...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol EIA Test

Description:... (E2) is the most potent, naturally secreted estrogen and is the major estrogen produced by the ovary [1]. In the ovary, ... [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and ...
Company:Diagnostic Systems Laboratories, Inc.

3rd Generation Estradiol RIA Test

Description:... (E2) is the most potent, naturally secreted estrogen and is the major estrogen produced by the ovary [1]. In the ovary, ... [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and ...
Company:Diagnostic Systems Laboratories, Inc.

Estrone Sulfate, Ultra-Sensitive RIA Test

Description:... Estrone Sulfate (E1S) is the most abundant circulating estrogen in non-pregnant women as well as normal men [1,2]. Estrone Sulfate is a ... Postmenopausal Woman. New York: Raven Press, 1993, p.57. Buster JE: estrogen metabolism. IN: Sciarra JJ (ed.): Endocrinology, Infertility, Genetics, ...
Company:Diagnostic Systems Laboratories, Inc.

Estrone Sulfate RIA Test

Description:... Estrone Sulfate (E1S) is the most abundant circulating estrogen in non-pregnant women as well as normal men [1,2]. Estrone Sulfate is a ... Postmenopausal Woman. New York: Raven Press, 1993, p.57. Buster JE: estrogen metabolism. IN: Sciarra JJ (ed.): Endocrinology, Infertility, Genetics, ...
Company:Diagnostic Systems Laboratories, Inc.

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Estrogen in Medical Definition

Growth attenuation

... Growth attenuation is an elective medical treatment which involves administering estrogen to cause closure of the epiphyses of the bones , resulting in a reduced adult height. Since the 1960s this treatment has been performed primarily ...
Estrogen in Medical Dictionary

Atrophic vaginitis

... of the vagina due to decreased production of estrogen . This may occur with menopause . Atrophic ... the vagina l walls. It is caused by a lack of estrogen . Atrophic Vaginitis What is atrophic ... tissue . This change happens when the level of estrogen in your body decreases. The condition also is ...

Atrophy

... of the vagina due to a decline in estrogen . It occurs most often after menopause . The most effective treatment is estrogen applied to the vagina l area, usually as a ... within the body produce little hormonally active estrogen . Atrophy A wasting or decrease in size of a ...

Birth Control

... fall under one of the following combinations of estrogen and progestin: ... Giving Men Some Birth ... hormone thyroid hormone s Tamoxifen., an estrogen blocker ... Birth control pills may be ... formation are: ... Children can be exposed to estrogen by ingesting birth control pills or ...

Bone Health

... for the health of bones," she explained. Low estrogen is good for you in the sense that it lowers your cancer risk ( estrogen is linked to some types of cancer ous cell growth). However, because estrogen also plays an important role in skin and bone ...

Breast

... is directed exclusively by female hormone s-- estrogen s. Although men have some estrogen in their system, it is usually insufficient to ... caffeine intake; high- fat diet ; diabetes . estrogen s and oral contraceptives have been linked to ...

Breast-feeding

... , I won't put her on a method that contains estrogen . I'll use either a progesterone -only pill, a ... end, your body stops making the female hormone estrogen (ES-truh-jun). estrogen controls how your body matures, your monthly ...

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Estrogen in Biological News

Evolution of a contraceptive for sea lamprey

... insights into the early evolution of the estrogen receptor, research by a team at the University of ... characterized the estrogen-binding site on the estrogen receptor in the sea lamprey. To accomplish this, ... a 3-D model of the structure of the lamprey estrogen receptor. The ...

Dual role in breast tissue for a protein involved in leukemia

... in developing breast cancer cells that are estrogen receptor-positive as compared to estrogen receptor-negative. When estrogen receptor levels were overexpressed, loss of ...

Lab study shows THC exposure as adolescents linked to negative effects of THC as adults

... at Louisiana State University had found that estrogen or more precisely, having ovaries made adult ... during the equivalent of adolescence, however, estrogen loses its protective effect. When these rats were ... results indicate that the effects of THC and estrogen are different, depending on age, and, even more ...

Internationally acclaimed researcher joins UH faculty thanks to $5.5 million grant

... bring an internationally recognized team to study estrogen action in normal and diseased tissues that will ... and expressed. Gustafsson discovered a major estrogen receptor protein and has worked in a variety of ... discovered the existence of a previously unknown estrogen receptor that plays a pivotal role in the ...

Hormone therapy associated with reduced colorectal cancer risk

... PHILADELPHIA The combination of estrogen plus progestin, which women stopped taking in ... who had never taken these hormones, the use of estrogen plus progestin was associated with a reduced risk ... was seen among women who had completed use of estrogen plus progestin five or more years previously. ...

HWI scientist first in world to unravel structure of key breast cancer target enzyme

... all three of the enzymes involved in controlling estrogen levels that can serve as drug targets for ... of all breast cancer tumors are estrogen-fed. estrogen is a female sex hormone and androgens are the ... was not known, nor the mechanism of androgen to estrogen conversion, the AIs currently in use have been ...

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Estrogen in Biological Technology

Bionovo Announces 2008 Highlights and Year-End Financial Results

... to the Endocrine Society indicating that estrogen receptor beta may have a role in cancer ... describing the structural elucidation of active estrogen receptor beta selective compounds from VG101, ... well provide superior efficacy and safety versus estrogen therapy. Full Year Result ...

Bionovo Announces Publication of Positive Phase 2 Trial Results for Menerba(TM)

... therapy for hot flashes." "Menerba is an estrogen receptor beta selective drug," said Jan Ake Gustafsson, M.D., the discoverer of estrogen receptor beta, from Houston University and a ... first Phase 2 clinical trial support the role of estrogen receptor beta as a novel target for treating ...

Bionovo Publishes Discoveries in Predictable Tissue Selectivity for Selective Estrogen Receptor Modulators Platform

... of specific tissue effect. "Selective estrogen modulators (SERMs) are an exciting class of drugs ... regulation in various tissues by each estrogen receptor subtype, provides a new platform for the ... Bionovo. "The discovery of these selective estrogen regulatory elements strengthens our SERM ...

Azur Pharma Ltd. Enters Into Definitive Agreement With BioSante Pharmaceuticals Inc [nasdaq: BPAX], to Acquire U.S. Rights to Elestrin (TM)

... of Elestrin. Azur will market Elestrin to estrogen prescribing physicians in the U.S., comprised ... practitioners who write the majority of estrogen prescriptions. Azur is in an excellent position to capture an important share of the U.S. estrogen therapy market, which is currently estimated at ...

Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated

... DX in 44 percent of patients with node- negative estrogen receptor-positive breast cancer. "The results ... to administer chemotherapy in node-negative estrogen receptor-positive breast cancer patients should ... of 85 consecutive patients with node-negative, estrogen receptor-positive breast cancer who had used the ...

Bionovo Develops a High Throughput LC-MS/MS Method for Simultaneous Quantification of Multiple Bioactive Compounds

... regulatory process." About MF101 MF101 is an estrogen receptor beta (ER-b) selective drug, developed ... of breast and uterine cancers is associated with estrogen receptor alpha (ER-a) activation and that estrogen receptor beta (ER-b) blocks the growth promoting ...

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Estrogen in Biological Products

ER-beta Fluorescence polarization Assay Kit from Invitrogen

Description:... estrogen Receptor (ER) Competitor Assay Kits Green for estrogen Receptors-alpha and -beta (ER-Alpha and ER-Beta) are ideal for screening novel estrogen receptor binding compounds and endocrine ...
Company:Invitrogen

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:... detects vitamin D receptor (VDR) from human, rat, mouse, hamster, chicken, amphibian, and fish tissues. This antibody does not cross-react with estrogen or glucocorticoid receptors. MA1-710 detects both the occupied and unoccupied forms of the receptor. MA1-710 has been successfully used in ...
Company:ABR-Affinity BioReagents
Estrogen in Biological Definition

Parthenogenesis

... to their hormonal cycles, which cause some to act as males when levels of estrogen are low, and others to take the role of female when estrogen levels are high. Lizards that act out the courtship ritual have greater ...

Anabolism

... catabolic. Classic anabolic hormones include Growth hormone IGF1 and other insulin-like growth factors Insulin Testosterone estrogen Classic catabolic hormones include Cortisol Glucagon Adrenalin and other catecholamines Cytokines Newer hormones ...

Cancer

... E or both experience a reduced incidence of prostate cancer in comparison to men taking placebo pills. Daily use of tamoxifen , a selective estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developing breast cancer in high-risk women by about 50%. ...

Anabolism

... catabolic. Classic anabolic hormones include Growth hormone IGF1 and other insulin-like growth factors Insulin Testosterone estrogen Classic catabolic hormones include Cortisol Glucagon Adrenalin and other catecholamines Cytokines Newer hormones ...
Estrogen in Biological Dictionary

Receptor

... alpha and beta receptors ... ... estrogen receptor , accessory proteins, ERE, estrogens, estrogen antagonists, ... Interaction of steroid- ... that specifically ... ( receptor ) ... Selective estrogen receptor modulator: Bazedoxifene, ... ...

Estrogen

... From menarche to menopause the primary estrogen is 17β-estradiol. ... In males, estrogen regulates certain functions of the reproductive system ... estrogen is a hormone or chemical messenger produced in ...

Hormone

... mess. For decades, women were told that HRT -- usually a combination of estrogen and ... Explains about hormone therapy, types of therapies, ... hormone replacement therapy HRT Explains the use of the hormones estrogen and progestin to treat symptoms and side effects of menopause. ...

Primary oocyte

... | Reference ... The primary oocyte produces yolk granules and the follicular cells change from ... is secreted by the primary oocyte . estrogen is secreted by granulosa ... ... oogenesis, only one functional fertilizable cell develops from a primary oocyte . ... to form several layers ...

Polysome

... Polysome preparation and probe labeling were performed as described (3) ... The highest amount of polysome -bound PMR1 was observed prior to estrogen ... Preparation of liver extracts, mRNP and polysome fractions ... ... splicing, translation, polysome , exon junction complex ... mRNA ...

Maternal effect

... of the possible maternal effect in multiple sclerosis is unknown, but ... That there is a maternal effect at all is ... Effect of estrogen on maternal behaviour after hysterectomy + ovariectomy. Summary table: Effect of hormones on maternal behaviour ... To measure the ...

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(Date:7/10/2014)... stabilize or even improve the state of fisheries ... in the Mediterranean has deteriorated over the past ... fish species reported in the Cell Press journal ... call for stringent monitoring of Mediterranean fishing activities, ... plans in Mediterranean waters. , Their data show ...
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(Date:7/10/2014)... controversy centres around a family of enzymes known as ... group in their active site. At the centre of ... becomes oxidised (ferryl) when a reacting heme is in ... has remained unanswered for decades is whether this oxidation ... group (OH). Resolving this fundamental question has implications for ...
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