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Erythropoietin in Medical News

Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa

... associated with neutralizing antibodies to erythropoietin have been reported in patients treated with ... for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT ... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not ...

Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases

... THURSDAY, May 8 (HealthDay News) -- A gene called erythropoietin (EPO) is linked to severe diabetic eye and kidney ... failure or chemotherapy. In the United States, erythropoietin represents one of the largest single drug ... need to consider blunting the effects of erythropoietin in addition, or as an alternative, to an ...

Drugs used for cancer-associated anemia linked with increased risk of blood clots, death

... in the February 27 issue of JAMA. The ESAs erythropoietin and darbepoetin are widely used to treat anemia ... in conjunction with basic science reports on erythropoietin and erythropoietin receptors in solid cancers, raise concern about ...

Drug for anemic cancer patients raises risk of death

... a significant effect when he added an ESA called erythropoietin to head and neck cancer cells in tissue culture. ... of a growing body of studies that demonstrate erythropoietin expression and function in a variety of human ... at a National Cancer Institute workshop on erythropoietin and tumor progression December 2007 in Bethesda, ...

Anemia treatment may be a double-edged sword

... erythropoietin has so far been known to doctors as a hormone ... causing blindness. The researchers measured erythropoietin produced in the retina as the disease progressed. ... into the retina. The researchers concluded that erythropoietin helps blood vessels survive and grow in the ...

New study examines the validity of epo testing

... BETHESDA, Md. (June 26, 2008)Recombinant human erythropoietin (rHuEpo) is a genetically engineered hormone sometimes misused by ... The Study The study is entitled, "Testing for Recombinant Human erythropoietin in Urine: Problems Associated with Current Anti-Doping Testing," and was ...

Anemia Drugs May Speed Tumor Growth in Some Cancer Patients

... a patient is susceptible to having their tumor progress if treated with erythropoietin and, alternatively, we may be able to predict patients it would be safe to ... phase III trial of erythropoietin. Scientists measured levels of erythropoietin receptor (EpoR) messenger RNA (mRNA). High levels of EpoR mRNA in ...

JCI table of contents: Jan. 24, 2008

... OPHTHALMOLOGY: I can see clearly now Epo has come and gone erythropoietin (Epo) is a hormone that stimulates red blood cell production and that is ... timing must be carefully regulated to prevent adverse effects. TITLE: erythropoietin deficiency decreases vascular stability in mice AUTHOR CONTACT: Lois ....

Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Updated Analysis of 2001 Epoetin Alfa Study Posted

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

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Erythropoietin in Medical Technology

XTL Biopharmaceuticals Announces the Acquisition of the Use Patent on Recombinant Erythropoietin (rHuEPO) for the Treatment of Multiple Myeloma

... for the rights to a use patent on Recombinant erythropoietin ("rHuEPO") for the prolongation of multiple ... second or third quarter of 2009. ABOUT erythropoietin (EPO) erythropoietin (EPO) is a glycoprotein cytokine produced mainly ...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... associated with neutralizing antibodies to erythropoietin have been reported in patients treated with ... for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT ... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not ...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

... associated with neutralizing antibodies to erythropoietin have been reported in patients treated with ... for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, ... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not ...

Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients

... thus effectively treating their anemia without receiving any injections of erythropoietin (EPO) during this period. One of the patients received his last EPO ... based on this technology: EPODURE - producing erythropoietin (EPO) to treat anemia INFRADURE - producing interferon-alpha ...

Observational Studies Assess the Potential Impact of Limiting Erythropoiesis-Stimulating Agent Availability on Frequency of Blood Transfusions

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

BioNumerik Pharmaceuticals and ASKA Pharmaceutical Co. Announce Results from Phase III Clinical Trial of Tavocept(TM)

... or prevent chemotherapy-induced anemia and to maintain or stimulate erythropoietin function or synthesis. Erythropoiesis is the process by which red blood cells are produced, and involves the release of a hormone called erythropoietin that stimulates the red bone marrow to begin red blood cell production. ...

Ortho Biotech Statement on U.S. Food and Drug Administration Oncologic Drugs Advisory Committee Vote

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Totality of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and Effective When Used Appropriately as Labeled to Treat Chemotherapy-Induced Anemia

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

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Erythropoietin in Medical Products

Erythropoietin (EPO) ELISA

Description:... is intended for the quantitative determination of erythropoietin (EPO) in human serum. This assay is intended for ... the advent of the administration of recombinant erythropoietin as a biologic therapy to increase red blood cell mass, an erythropoietin assay may be used also to aid in the prediction ...
Company:MD Biosciences

CGMS System Gold Continuous Glucose Monitoring

Description:... Evaluation of therapeutic changes to medication regimen Evaluation of behavioral modifications affecting glycemic control Patients undergoing erythropoietin therapy because HbA1c may be unreliable. ...
Company:Medtronic MiniMed

EPO EIA Human Cytokines 021-SDX021 Erythropoietin Anemia

Description:... EPO EIA Human Cytokines 021-SDX021 erythropoietin ...
Company:ALPCO Diagnostics
Erythropoietin in Medical Dictionary

Erythropoietin

... erythropoietin test Definition erythropoietin , also called EPO, is a type of protein c alled ... the production of red blood cells. EPO ( erythropoietin ) is a protein hormone produced by ...

Anemia

... with kidney disease . Healthy kidney s produce a hormone called erythropoietin , or EPO, which stimulates the bone marrow to produce the proper number ... undergoing chronic hemo dialysis who are receiving supplemental erythropoietin therapy. In elderly people, it is associated with pernicious anemia ...

Bone marrow

... II/III clinical trials . Healthy kidney s produce a hormone called erythropoietin , or EPO, which stimulates the bone marrow to produce the proper number ... This article outlines the mechanisms of o edema and possible causes. erythropoietin (EPO) - Stimulates the bone marrow to produce red blood cells Renin ...

Marrow

... the organ it invades. Healthy kidney s produce a hormone called erythropoietin , or EPO, which stimulates the bone marrow to produce the proper ... This article outlines the mechanisms of o edema and possible causes. erythropoietin (EPO) - Stimulates the bone marrow to produce red blood cells ...

Oxygen

... high blood pressure . Healthy kidney s produce a hormone called erythropoietin , or EPO, which stimulates the bone marrow to produce the proper number ... S: Red blood cells whose major function is to carry oxygen to cells. erythropoietin : A glyco protein that stimulates production of red blood cells. ...

Renin

... the hormone renin . That, in turn, increases your blood pressure . erythropoietin (EPO), which stimulates the bone marrow to make red blood cells ... called renin , which monitors blood pressure , and a hormone called erythropoietin , ... beneath the capsule surrounding the kidney ) or, less often, by ...

Aldosterone

... aches , spasm s, and, sometimes, paralysis .) ... Examples of hormone s include aldosterone , antidiuretic hormone ( ADH ), cortisol , erythropoietin , estrogen , human chorionic gonad otropin (hCG), parat hormone , progesterone , and testosterone . The adrenal glands are located just ...

Chronic renal failure

... gradually declines, usually over a period of years. Chronic renal failure may produce a similar anemia because it causes reduced levels of erythropoietin , the hormone that stimulates the production of red blood cells in the bone marrow . ^ Top ... Chronic renal failure symptoms that ...

Congenital Heart Disease

... cor pulmonale pulmonary fibrosis Polycythemia vera Dehydration (such as from severe diarrhea ) Renal ( kidney ) disease with high erythropoietin production ... Congenital heart disease These are forms of heart disease that develop before birth ( congenital ). Congenital heart ...

Cor pulmonale

... cor pulmonale pulmonary fibrosis Polycythemia vera Dehydration (such as from severe diarrhea ) Renal ( kidney ) disease with high erythropoietin production ... The liver may be increased in size, which sometimes can occur because of right -sided heart failure ( cor pulmonale ). The ...

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Erythropoietin in Biological News

A search for protection against chemotherapy cardiotoxicity

... of Grenoble, in France, have discovered that erythropoietin administration prevents acute cardiotoxic effects ... research article describing this work entitled erythropoietin pretreatment protects against acute chemotherapy ... effect afforded by recombinant human erythropoietin (rhEPO) against various stresses, through ...

Brain-nourishing molecule may predict schizophrenia relapse

... levels. Two drugs currently on the market for other medical conditions erythropoietin for anemia and cysteamine for cystinosis can as well. Dr. Pillai hopes ... along with any of the above drugs. He adds that both cysteamine and erythropoietin have been well studied for their potential to enhance cognitive function. ...

American Chemical Society's Weekly PressPac -- Aug. 6, 2008

... drugs, including round-the clock monitoring of urine and blood samples. Many of these tests will focus on identifying human growth hormone (hGH) and erythropoietin (EPO), two products of recombinant DNA technology that athletes have used to boost muscle mass and increase endurance. Although analytical ...

Cell Therapy for Cardiovascular Diseases

... myocardial infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Data presented by Dr. ...

Top scientists meet for global conference on stem cell therapy for cardiovascular diseases

... infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Data ...

Fourth Annual International Conference on Cell Therapy for Cardiovascular Diseases

... myocardial infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Bone marrow-derived stem ...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

... N-glycans today in the September 8, 2006 issue of the journal Science . To demonstrate the utility of the engineered yeast strains, recombinant erythropoietin (Epo), a protein that stimulates the production of red blood cells, was expressed, purified and its activity demonstrated in vivo. ...

Mutation in blood stem cells provides clues to cancer development

... mutation in the JAK2 signaling pathway allows the cells to bypass the body's usual mechanism of red blood-cell production, the binding of the hormone erythropoietin (EPO) to its receptor, a process which normally regulates the production of red blood cells. As a result of this intrinsic defect, the bone marrow ...

Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack

... in Philadelphia, and his co-workers knew that the drug Darbepoietin alpha would protect the ischemic heart. Darbepoietin is a long-acting cousin of erythropoietin (EPO), which has been shown to offer some protection to the heart from injury from ischemia, or a lack of oxygen. In previous studies, Dr. Koch had ...
Erythropoietin in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... associated with neutralizing antibodies to erythropoietin have been reported in patients treated with ... for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT ... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not ...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

... and Mortality Associated with Recombinant erythropoietin and Darbepoetin Administration for the ... associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal ... for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, ...

PROLOR Biotech Awarded Two U.S. Patents for Its Longer-Acting Human Growth Hormone and Longer-Acting Erythropoietin

... long-acting CTP-enhanced human growth hormone (hGH-CTP) and human erythropoietin (EPO-CTP). The patents cover the composition of PROLOR's proprietary ... "These two new patents covering CTP-enhanced human growth hormone and erythropoietin represent another significant layer of protection within our CTP-based ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Ortho Biotech Supports FDA Advisory Committees' Recommendations on Use of ESAs in Chronic Renal Failure Patients

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving ... to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently ...

Preclinical Data From Amgen's Oncology Pipeline to be Presented at AACR

... (TAMs) and tumor growth in vivo Lead author: Bonham L. Abstract No. 2077 (Monday, April 20, 2009, 3:40 pm - 3:55 pm) -- erythropoietin Receptor (EpoR) Was Expressed at Low to Undetectable Levels in Tumor Cell Lines: Expression Was Not Regulated by Hypoxia and No ...

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2008 Results

... year's presentation basis. Fiscal Year 2008 Business Highlights: -- EPIAO, the Company's flagship injectable recombinant human erythropoietin ("EPO") products, continued to outpace EPO market growth in China. Net revenue from EPIAO increased 32.0% year-over-year in the fourth ...

3SBio Inc. Announces Third Quarter 2008 Results

... -- Total net revenues increased 21.6% over the third quarter 2007 to RMB68.2 million (US$10.0 million). -- Net revenue from recombinant human erythropoietin ("EPO") products, marketed under the EPIAO brand, increased 17.5% over the third quarter 2007 to RMB42.7 million (US$6.3 million). -- Net ...

Medgenics Announces Encouraging Preliminary Data For Phase I/II Clinical Trial of EPODURE In Renal Anemia

... of a range of chronic diseases. Medgenics currently has two products in development based on this technology: -- EPODURE -- producing erythropoietin (EPO) to treat anaemia -- INFRADURE -- producing interferon-alpha (IFN-a) to treat hepatitis C The Company has demonstrated proof of principle of ...
Erythropoietin in Biological Products

Human Erythropoietin, Unconjugated from R&D Systems

Description:... Recombinant Human erythropoietin (Tissue Culture ...
Company:R&D Systems
Erythropoietin in Biological Definition

Hormone

... AVP) atrial-natriuretic peptide (ANP, also atriopeptin) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone (CRH) erythropoietin ( EPO ) follicle stimulating hormone (FSH) gastrin glucagon gonadotropin-releasing hormone (GnRH) growth hormone-releasing ...

Kidney

... . Renal functions Renal functions include the excretion of waste material from the bloodstream, secretion of hormones - particularly erythropoietin and renin and maintaining serum electrolyte, acid-base levels and osmolality. For more info see Renal physiology . Diseases and disorders ...
Erythropoietin in Biological Dictionary

Glycoprotein

... ... Information about glycoprotein in the free online English ... erythropoietin - a glycoprotein secreted by the kidneys that stimulates the ... ... ... requires particular kinds of CSFs; for example, the CSF erythropoietin is ... Cancer is a leading cause of death worldwide with WHO global ...
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