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Erythematosus in Medical News

Anxiety and depression lower quality of life in majority of systemic lupus erythematosus patients

... June 2009: 92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which ... and extra-cerebral involvement, Systemic Lupus erythematosus Disease Activity Index (SLEDAI) and the Systemic Lupus erythematosus International Collaborating Clinics (SLICC) ...

Uptake of Branded Agents Will Drive the Systemic Lupus Erythematosus Drug Market to Quadruple to $1.4 Billion in 2016

... branded agents will drive the systemic lupus erythematosus drug market to quadruple from approximately $325 ... The new Pharmacor report entitled Systemic Lupus erythematosus finds that the strongest drivers of market growth ... regimens of patients with systemic lupus erythematosus will result in increased polypharmacy," said ...

'Multi-target' immune therapy improves outcomes of severe lupus nephritis

... occurring in patients with the immune system disease systemic lupus erythematosus (SLE). All patients had "class V+IV" disease, meaning widespread ... effects was also lower with multi-target therapy. Systemic lupus erythematosus is an autoimmune disorder, in which the immune system attacks healthy ...

New Batch of Lupus Genes Discovered

... Langefeld, co-director of the International Consortium for Systemic Lupus erythematosus Genetics (SLEGEN), which produced the discoveries reported in Nature ... Langefeld, M.D., co-director, International Consortium for Systemic Lupus erythematosus Genetics (SLEGEN), and director, Center for Public Health Genomics, Wake ...

Scripps research scientists find new genetic mutation that halts the development of lupus

... target for lupus. Two Sides of Lupus Genetics Systemic lupus erythematosus is a serious autoimmune disease that affects approximately 1.5 million ... has been considerable interest in defining the genetics of systemic lupus erythematosus in recent years, not only for gaining a better understanding of the ...

Immune responses to flu vaccine are diminished in lupus patients

... Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs. Because ...

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Erythematosus in Medical Technology

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

... patients with serologically active systemic lupus erythematosus (SLE). In the placebo-controlled BLISS-52 study, ... agreement. About Systemic Lupus erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune ...

Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus

... with active moderate and severe systemic lupus erythematosus (SLE). These findings were presented at the ... investigation for the treatment of systemic lupus erythematosus (SLE). CD22 is a B-cell specific surface protein ... Morris Plains, NJ, USA. About systemic lupus erythematosus (SLE) Systemic ...

Human Genome Sciences Completes Enrollment in Second Phase 3 LymphoStat-B(R) Trial

... in patients with active systemic lupus erythematosus (SLE). Belimumab is being developed by HGS and ... Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune ... at http://www.lupus.org or the European Lupus erythematosus Federation at http://www.elef.rheumanet.org . ...

Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials

... in patients with active systemic lupus erythematosus (SLE). LymphoStat-B is being developed by HGS and ... Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune ... at http://www.lupus.org or the European Lupus erythematosus Federation at http://www.elef.rheumanet.org . ...

Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus

... of care in patients with active systemic lupus erythematosus (SLE). The results will be the subject of an oral ... under the agreement. About Systemic Lupus erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-threatening disease. The ...

Human Genome Sciences Reports Substantial Progress Toward Commercialization and Announces 2009 Goals at JPMorgan Healthcare Conference

... the results of our two Phase 3 trials of LymphoStat-B in systemic lupus erythematosus (SLE) in July and November, respectively, and expect to file marketing ... trials of LymphoStat-B (belimumab) in patients with active systemic lupus erythematosus (SLE). The Company expects to report the first Phase 3 data for ...

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Erythematosus in Medical Products

ImmunoDOT™ DNA/ENA Autoimmunity Screening Panel

Description:... against various specific nuclear antigens (ANA, DNA, SS-A/SS-B, RNP/Sm) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), and Sjgren's ....
Company:GenBio

ImmunoDOT Autoimmunity Screening Panel 6

Description:... various specific nuclear antigens (SS-A, SS-B, RNP/Sm, Sm, Jo-1, and Scl-70) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), Sjgren's syndrome and other rheumatoid ....
Company:GenBio

ImmunoDOT Autoimmunity Screening Panel 4

Description:... against various specific extractable nuclear antigens (SS-A, SS-B, RNP/Sm, and Sm) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), and Sjgren's ....
Company:GenBio

ImmunoWELL Cardiolipin Antibody (IgM) Test

Description:... detection of antibodies to cardiolipin antigen in serum and is used as an aid for assessing the risk of thrombosis in individuals with systemic lupus erythematosus (SLE) and lupus-like ....
Company:GenBio

ImmunoWELL Cardiolipin Antibody (IgG) Test

Description:... detection of antibodies to cardiolipin antigen in serum and is used as an aid for assessing the risk of thrombosis in individuals with systemic lupus erythematosus (SLE) and lupus-like ....
Company:GenBio

SS-A (Ro)Anti-Extractable Nuclear Antigen (ENA) Antibodies Kit

Description:... (ENA) [RNP, Sm, SS-A (Ro), or SS-B (La)] in human serum. SS-A (Ro) and SS-B (La) antibodies aid in the diagnosis of SLE, subacute cutaneous lupus erythematosus (SCLE) and Sjgrens ....
Company:IMMCO Diagnostics

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Erythematosus in Medical Dictionary

Autoimmune disease

... autoimmune disease s (such as systemic lupus erythematosus ), tuberculosis , mononucleosis , ... Many ... invaders, such as virus es. Systemic lupus erythematosus ( lupus , SLE) is an autoimmune disease in ... damage and dysfunction. Systemic lupus erythematosus (SLE) is an autoimmune disease , which means ...

Discoid lupus erythematosus

... Discoid lupus erythematosus Definition Discoid lupus erythematosus (DLE) is a disease in which coin-shaped ... red bumps appear on the skin . Discoid Lupus erythematosus . About 20% of patients have discoid lesion s. ...

Lupus

... of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system . SLE ... and brain. Lupus Overview Systemic lupus erythematosus ( lupus , SLE) is an autoimmune disease in ... is one complication of systemic lupus erythematosus (SLE ). It is related to the auto immune ...

Lupus erythematosus

... LE ( lupus erythematosus ) cell test measures the presence of a special ... found mostly in patients with systemic lupus erythematosus . Pictures & Images Systemic Lupus erythematosus Rash on the Face ... Discoid ...

Lupus nephritis

... of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system . SLE ... that is a complication of systemic lupus erythematosus , characterized by damage to the glomerulus and ... Lupus Nephritis Lupus ( Systemic Lupus erythematosus ) Lyell's Syndrome ( Erythema Multiforme ) Lyme ...

Nephrotic syndrome

... disease s (such as diabetes mellitus and lupus erythematosus ). Nephrotic syndrome There is not enough ... clear conclusion in this area (145;146). C Lupus erythematosus There is not enough reliable evidence to form a ... a bodywide infection stroke systemic lupus erythematosus , an auto immune disorder in which the body ...

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Erythematosus in Biological News

Steps toward Stopping Autoimmune Disease

... genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an ... Lupus Research (ALR) formed and supported the International Systemic Lupus erythematosus Genetics (SLEGEN) Consortium, charging scientists with searching for ...

Genes linked with lupus are revealed, giving hope for new treatments

... Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupus erythematosus or SLE) and mutations in several different genes. The findings, by scientists from Imperial College London and institutions in the USA and ...

DNA variations signal lupus risk

... in the journal Nature Genetics . The study, the largest of its kind to date, is the work of the International Consortium for Systemic Lupus erythematosus (SLEGEN), of which UAB is a member. SLE is the medical term for systemic lupus erythematosus, a common form of the disease. Looking at the genomes ...

UT Southwestern secures $5 million NIH grant for lupus research

... grant from the National Institutes of Health to fund the Center of Research Translation, which will investigate the autoimmune disease systemic lupus erythematosus (SLE). There are a limited number of these centers around the country, so this is a major accomplishment for UT Southwestern, said Dr. David Karp, ...

Lupus gene finding prompts call for more DNA samples

... called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease. Lupus or Systemic Lupus erythematosus (SLE) is an autoimmune disease which frequently causes skin rash, joint pains and malaise, but can also lead to inflammation of the kidneys and ...

HGS announces positive Phase 2 LymphoStat-B at ACR meeting

... flares over time, and was well tolerated through 2.5 years on treatment in combination with standard of care in patients with active systemic lupus erythematosus (SLE). The results will be the subject of an oral presentation today in Boston at the Annual Scientific Meeting of the American College of ...

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Erythematosus in Biological Technology

Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus

... patients with serologically active systemic lupus erythematosus (SLE). The results were presented today in ... under the agreement. About Systemic Lupus erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune ...

Corgenix Announces FDA Clearance for IgG Anti-AtherOx(R) Test Kit

... test for individuals with systemic lupus erythematosus and lupus-like disorders expands Corgenix' ... in individuals with systemic lupus erythematosus and lupus-like disorders. Corgenix licensed this ... I (B2GPI) in individuals with systemic lupus erythematosus (SLE) and lupus-like disorders (antiphospholipid ...

Human Genome Sciences to Host July 20 Conference Call to Discuss Top-Line Phase 3 Results for Benlysta(TM) (Formerly Lymphostat-B(R)) in Systemic Lupus Erythematosus

... July 20, from BLISS-52, the first of two pivotal Phase 3 clinical trials of BENLYSTA(TM) (belimumab, formerly LymphoStat-B(R)) in systemic lupus erythematosus (SLE). (Logo: http://www.newscom.com/cgi-bin/prnh/20080416/HGSLOGO ) Senior management will host a conference call to discuss the ...

Trubion Pharmaceuticals, Inc. Announces Initiation of Phase 1 Study of SBI-087 for the Treatment of Systemic Lupus Erythematosus (SLE)

... (NYSE: WYE ), has initiated a Phase 1 clinical trial of SBI-087, Trubion's next generation CD20 drug candidate, for the treatment of systemic lupus erythematosus (SLE). Based on Trubion's Small Modular ImmunoPharmaceutical (SMIP(TM)) technology, SBI-087 is also being evaluated in a Phase 1 clinical trial for ...

Trubion Pharmaceuticals Inc. Announces Work-Force Reductions and Restructuring

... Phase 1 rheumatoid arthritis trial data by end of Q4 2009 (currently enrolling; conducted by Wyeth) -- Initiate SBI-087 Phase 1 systemic lupus erythematosus trial by end of Q1 2009 (conducted by Wyeth) "Concentrating our resources on our clinical stage product candidates, as well as our ...

Cephalon's New Product Launches Pace Record 2008 Sales

... Recently we announced a number of deals including the worldwide license for the drug candidate LUPUZORTM, for the treatment of systemic lupus erythematosus and the option to acquire Ception Therapeutics including its drug candidate reslizumab for eosinophilic esophagitis. Our ability to move quickly ...
Erythematosus in Biological Definition

Apoptosis

... factor in the pathogenesis of numerous diseases including cancer, neuro-degenerative and ischemic diseases, AIDS and autoimmunity. In systemic lupus erythematosus (SLE) the antigen responsible for most anti-DNA antibodies, exclusively generated in this disease, are derived from nucleosomes. As nucleosomes are ...

Immune system

... On the other end of the scale, an overactive immune system figures in a number of other disorders, particularly autoimmune disorders such as lupus erythematosus , type I diabetes (sometimes called "juvenile onset diabetes"), multiple sclerosis , psoriasis , and rheumatoid arthritis . In these the immune ...

Immunology

... include chronic granulomatous disease ), and autoimmunity , in which the immune system attacks its own antigens (examples include systemic lupus erythematosus , rheumatoid arthritis , Hashimoto's disease and myasthenia gravis ). Other immune system disorders include different hypersensitivities , in ...
Erythematosus in Biological Dictionary

Serosa

... adventitia a layer ... The serosa reduces friction as the digestive system organs work and slide across ... Clinical overview of Systemic Lupus erythematosus (SLE), a chronic, ... the joints, skin, kidney, brain, lung, heart, serosa and gastrointestinal tract. ... ... the internal reproductive organs ...

Pericardium

... on Diseases of the pericardium ... Ongoing Trials on Diseases of the pericardium at Clinical Trials.gov ... pericardium . systemic lupus erythematosus ... Chest x-rays may detect calcium deposits in the pericardium . ... Normally, the pericardium is less than 1/8 inch ... Chest x-rays may ...
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