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DNA in Medical News

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots

... Corporation is pleased to report that their dna recovery product, GenSolve(TM), is enabling ... groups, from diverse research areas, to recover dna from Guthrie cards and FTA paper for microarray ... GenSolve(TM) methodology is capable of recovering dna of sufficiently high quality for use in ...

Silenced genes as a warning sign of blood cancer

... changes that do not change the sequence of dna building blocks. Such labels are found ... able to show that methylation patterns in murine dna are largely corresponding to those found in ... be switched on or off by chemical labeling of the dna or ...

Unlocking the key to human fertility

... of Bradford, have found that sperm writes a dna signature that can only be recognised by an egg ... we have discovered is a previously unrecognised dna packaging 'signature' in mammalian sperm that may ... normally. Notably, disturbances in human sperm dna packaging are known to cause male infertility and ...

New test for safer biomedical research results

... and needs no more than ten copies of foreign dna in the cell sample to be positive. This is a ... The method is based on multiplication of specific dna sequences by polymerase chain reaction and subsequent detection of the multiplied dna regions. A special advantage of the new test is ...

Comprehensive Look at Rare Leukemia Finds Relatively Few Genetic Changes Launch Disease

... microarrays to chart genome-wide regions of dna gain or loss, which are known as copy number ... point mutations, the researchers also performed dna re-sequencing of 25 genes that are commonly ... ALL patients, a more common cancer, had that much dna damage. Even more surprising, 34 percent of ...

Scientists Track Impact of DNA Damage in the Developing Brain

... brain cells targeted by faulty single-strand dna repair and offers new hints about the roots of ... 27 /PRNewswire-USNewswire/ -- Switching off a key dna repair system in the developing nervous system is ... known as cerebellar interneurons are targeted for dna damage and are a likely source of neurological ...
DNA in Medical Technology

DNA Helps Reunite Children With Their Families

... Project (Program for Kids Identification with dna Systems ). PROKIDS is an international humanitarian effort using dna testing to deter human trafficking of children ... parents. Through the DNA-PROKIDS program, dna samples will be obtained from children associated ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... and can result in site-specific changes in the dna sequence. Previously, ZFNs were used to knock ... By engineering ZFPs that recognize a specific dna sequence Sangamo has created ZFP transcription ... INSERM routinely generates transgenic rats using dna or lentiviral vector microinjection. The ...

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

... mechanisms for brostallicin, a synthetic dna minor grove binder, and to identify differences ... the NCI research indicates that the tumor cell dna damaging effects of brostallicin are enhanced by ... tumors. Brostallicin was shown to affect dna in both dividing and quiescent cells. Its actions ...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

... by the HC2 test had detectable levels of HPV dna by the PCR-MS method," said Divya Patel, PhD, ... women who had been routinely screened for HPV dna using the HC2 test, the most widely used clinical ... by PCR-MS. In all these cases, degenerate dna sequencing failed to detect any of the 13 ...

ADHD Genes Found; Known to Play Roles in Neurodevelopment

... -- Missing dna Segments May Suggest Future Drug Targets -- ... Psychiatry . Unlike changes to single dna bases, called SNPs or "snips," the alterations ... strongly influenced by genetics. Drawing on dna samples from the Children's Hospital pediatric ...

Novel Vaccine Approach Offers Hope in Fight Against HIV

... proven to work against SIV in the laboratory, dna representing SIV-specific immunoadhesins was ... into a carrier virus designed to deliver the dna to monkeys. The researchers chose ... because it is a very effective way to insert dna into the cells of a monkey or human. In the ...
DNA in Medical Products

ViralXpress™ DNA/RNA Extraction Reagent

Description:... nucleic acids; however, the kit does not separate dna from RNA. Purification of either RNA or dna can be achieved by incubating the purified ... extraction and purification of a broad range of dna and RNA viruses from a variety of sources. ...
Company:CHEMICON International

Agarose - Separation >500 bp Genetic Performance Certified™

Description:... Digestion: Passes test Ligation: Passes test dna Binding: Passes test Blotting: Passes test Gel Background: Passes test dna Resolution: Passes test Separation Guidelines: ... 2000 - 50 bp Applications: *Separation of dna or RNA fragments greater than or equal to 500 bp. ...
Company:USB Corporation

Agarose MP

Description:... acids and separation of high molecular weight dna [pulsed-field gel electrophoresis (PFGE)]. ... gel strength reduces separation times for large dna molecules while maintaining high resolution. ... separation of nucleic acids. Biologically active dna can be recovered ....
Company:Roche Applied Science

UltraClean™ Forensic Agarose

Description:... Agarose is a premium agarose used for isolating dna fragments larger than 1000bp. This agarose ... to be free of DNase activity, RNase activity and dna contamination. Meets all requirements for dna identity ....
Company:Mo Bio Laboratories, Inc.

UltraPure™ Agarose 1000

Description:... formulated for high resolution of small dna RNA and PCR fragments <1000 bp. This standard melting temperature agarose can resolve dna fragments with as little as 10 bp difference in ... can be used for:- -High resolution separation of dna RNA and PCR fragments <1000 bp-Recovery ...
Company:Invitrogen

UltraPure™ Agarose

Description:... UltraPure™ Agarose resolves dna and RNA fragments from 100 bp to >30 kb. ... can be used in:- -Analytical separation of dna RNA and PCR fragments >1000 bp- Recovery of dna RNA and PCR fragments >1000 bp- Southern and ...
Company:Invitrogen
DNA in Medical Definition

Pathology

... cells may activate specific genetic programs to protect their vital proteins and organelles from heat shock or hypoxia , and may activate dna repair pathways to fix damage to chromosomes from radiation or chemicals. Hyperplasia is a long-term adaptive response of cell division and ...

Personalized medicine

... genes and families are being identified by genetic testing and research at a break neck pace. Because all cancers require a dysfunction in the dna of cells that regulate growth, it would be foolhardy not to expect all cancers to have some heritable predisposition as well as environmental ...

Sexual orientation and medicine

... ^ http://www.baphr.org/about/default.asp ^ Hamer, Hu, Magnuson, Hu and Pattatucci (1993) A linkage between dna markers on the X chromosome and male sexual orientation. Science 261(5119): pp. 321-7. ^ Healthy People 2010, 2nd ed. "A Systematic Approach to ...

Thymocyte

... gene fragments. In order to create a functional T cell receptor, the double negative thymocytes use a series of DNA-interacting enzymes to clip the dna and bring separate gene fragments together. The outcome of this process is that each T cell receptor has a different sequence, due to different ...
DNA in Medical Dictionary

Chromosomes

... viewed under the microscope. Chromosomes and dna See all Pictures & Images Overview, Causes, ... inherited characteristics are passed on. 1944 - dna is first connected to the inheritance of ... first sharp X-ray diffraction photographs of dna are obtained. Normally, an infant inherits ...

Gene

... & Participants ... GENE : 1. A unit of dna that carries information for the biosynthesis of ... protective substances. Gene Expression and dna Repair Research Interest: Expression of mRNA in ... in the gene result in many extra copies of a dna segment called a trinucleotide repeat (GAA). ...

Left

... behind; with piles that itch and bleed. dna Damage - Injuries to dna that introduce deviations from its normal, intact ... unrepaired, result in a MUTATION or a block of dna REPLICATION. The spleen is located in the ...

Mutation

... permanent change, a structural alteration, in the dna or RNA. In humans and many other organ isms, ... Mutation , germline: A heritable change in the dna that occurred in a germ cell (a cell ... 's and LRRK2. Mutation s (or changes in the dna that codes for a gene ) have occurred over time ...

Adenoviruses

... in addition to the primary therapy. Major groups of double-stranded dna virus es (class I virus es) include the adenoviruses , the herpes virus es, and the poxviruses. Major groups of single-stranded dna virus es (class II virus es) include the parvoviruses and coliphages. ...

Chromosome

... the nucleus (central structure) of each cell . Chromosome Analysis dna Testing Genetic Screening Genetic Testing Identity Testing ... (fluorescence in situ hybridization) technology, uses fluorescent-labeled dna probes which allow direct visualization of extra copies of chromosome s ...
DNA in Biological News

DNA computation gets logical at the Weizmann Institute of Science

... Biomolecular computers, made of dna and other biological molecules, only exist today ... introduced the first autonomous programmable dna computing device in 2001. So small that a ... involving multiple rules and facts, and the dna computing devices were able to deduce the correct ...

UC San Diego engineer provides insights to decades-old DNA squabble

... internal structure of chromatin, a key player in dna regulation, to reconcile a longstanding ... decades. Chromatin is a complex combination of dna and proteins that makes up chromosomes. The function of chromatin is to package dna into a smaller volume to fit in the cell. ...

Study links virus to some cases of common skin cancer

... cells had a mutation that could enable the viral dna to integrate into the dna of the host cell. "This is indirect evidence ... O. Hans Iwenofu and Sara B. Peters, examined dna samples from SCC tumors; from normal-appearing ...

University of Toronto helps to 'barcode' the world's plants

... the world's plants using a technique known as dna barcoding a rapid and automated classification ... that uses a short genetic marker in an organism's dna to identify it as belonging to a particular ... to long-term human existence on the planet." dna barcoding has been widely used to identify animal ...

UBC researchers help push for standard DNA barcodes for plants

... international team recommending standards for the dna barcoding of land plants, a step they hope will ... efforts. Barcodes based on portions of dna the taxonomical equivalent to UPC barcodes on ... species in many animal groups. However, because dna varies less between plant species, determining ...

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... microarrays to chart genome-wide regions of dna gain or loss, which are known as copy number ... point mutations, the researchers also performed dna re-sequencing of 25 genes that are commonly ... ALL patients, a more common cancer, had that much dna damage. Even more surprising, 34 percent of ...
DNA in Biological Technology

GeoVax Labs, Inc. Provides Clinical Studies Update

... unique two component vaccine, a recombinant dna and a recombinant modified vaccinia Ankara (MVA), ... from many other vaccine candidates. GeoVax's dna and MVA vaccines are used in a prime-boost protocol in which priming is done with the dna and boosting with the MVA. Both ...

ImmunoVaccine Technologies Partners With Scancell to Advance DNA Vaccine Delivery

... system for Scancell's novel ImmunoBody(R) dna vaccines. "Scancell is developing an exciting dna vaccine technology and we are delighted to enter ... technology has the potential to better deliver dna vaccines to draining lymph nodes to produce high ...

Bacteria pack their own demise

... DNA. Every human cell contains 46 neatly folded dna strands that together measure two meters, while ... do with around one millimetre of DNA. A piece of dna containing the recipe for one characteristic, ... is well. However, if for some reason the piece of dna where the T-A gene is located gets damaged or ...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... Activated Matrix technology and protein-producing dna gene portfolio are important building blocks as ... any biocompatible matrix containing a gene or dna vector encoding for a growth factor or any ... proteins based on the protein-producing dna of choice. Compared with current protein ...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

... dna Software, Inc. has been awarded three Fast Track ... nucleotides, and model the reaction rates of dna and RNA experiments. (Vocus) July 22, 2009 -- dna Software, Inc. has been awarded three Fast Track ...

Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International

... skin cells without the integration of foreign dna into the genome. This non-integrating ... genes are not an innate part of the cell's dna and are integrated directly into the genome via a ... risks associated with the insertion of foreign dna into the cell's genome. For example, insertion ...
DNA in Biological Products

MasterPure Plant Leaf DNA Purification Kit from EPICENTRE Biotechnologies

Description:... The MasterPure™ Plant Leaf dna Purification Kit is designed for isolating dna from 35-100 mg of fresh plant leaf tissue. The ... up to obtain larger amounts of DNA. The purified dna can be used for PCR amplification, restriction ...
Company:EPICENTRE Biotechnologies

Easy Clean DNA Spin Filter from Primm Labs

Description:... spin filters allow for the rapid isolation of dna from high melt agarose. Simply place your dna gel slice in the spin filter, centrifuge for 3 minutes, and the majority of your dna is recovered. There is no need to melt agarose or ...
Company:Primm Labs

DNAclear Kit from Ambion

Description:... Kit is designed to purify double-stranded dna (dsDNA) generated by enzymatic reactions such as ... and PCR. The process is simple and fast. dna amounts ranging from 1 ng to 3 g can be ... DNAclear procedure consists of three steps: 1) dna is bound to the Microfilter Cartridge in the ...
Company:Ambion

ExcelGel DNA Analysis Kit from GE Healthcare, formerly Amersham Biosciences

Description:... ExcelGel dna Analysis Kit, 1. *Fast, reproducible identification of dna polymorphisms and high resolution dna typing. *Semi-dry system offers fast and ...
Company:GE Healthcare, formerly Amersham Biosciences

Gelzyme enzyme from Invitrogen

Description:... molecules will not interfere with subsequent dna manipulation. dna isolated with Gelzyme enzyme can be used for ... Gelzyme enzyme is ideal for isolating dna from low melting temperature agarose gels. It is ...
Company:Invitrogen

Nucleon HT Genomic DNA Extraction Kit from GE Healthcare, formerly Amersham Biosciences

Description:... the simple, phenol-free extraction of genomic dna from paraffin-embedded sections and hard tissue ... kit is designed to recover high quality dna from 50 preparations of up to 25 mg of hard ... and Amplification of Genomic DNA, Nucleon dna Extraction ....
Company:GE Healthcare, formerly Amersham Biosciences
DNA in Biological Definition

Alternative splicing

... When the pre-mRNA has been transcribed from the dna , it includes several introns and exons . In ... as a twofold information structure: A dna sequence coding for the pre-mRNA An additional dna code or other regulating process, which regulates ...

Apoptosis

... damage or infection 1.2 Response to stress or dna damage 1.3 Homeostasis 1.4 Development ... of cervical cancer . Response to stress or dna damage Stress conditions (such as starvation) as well as damage to the cell's dna resulting from toxicity or exposure to ionizing ...

Bacterial conjugation

... structures through which the actual exchange of dna takes place; rather, some proteins coded in the ... a channel between the bacteria. The transfer of dna always runs from the F-positive towards the ... free, a nick is produced in one of the circular dna strands of the plasmid. Then, the ...

Biology

... which is based upon the nucleic acid dna using a universal genetic code . In ... phylogeny. These include the comparisons of dna sequences conducted within molecular biology ... techniques from molecular biology to determine dna sequences which assist in understanding the ...

Sticky end/blunt end

... resulting from the breaking of double-stranded dna . dna exhibits a stabilizing interaction between ... strands of DNA. If two complementary strands of dna are of equal length, then they will terminate in ...

Bacterium

... transformation (the transfer of naked dna from one bacterial cell to another in solution, ... of viral, bacterial, or both bacterial and viral dna from one cell to another via bacteriophage) and; bacterial conjugation (the transfer of dna from one bacterial cell to another via a special ...
DNA in Biological Dictionary

Z-DNA

... Z - dna is one of the many possible double helical structures of dna . It is a left-handed double helical structure in ... winds to the left in a zig-zag pattern . Z - dna is thought to be one of ... left-handed ...

Zinc finger

... domains can be engineered to target desired dna sequences which enables zinc - finger nucleases ... to make a ... What sequence in which dna chain is contacted by zinc finger 3? answer ... GATA-4, -5, and -6 - J. Biol. Chem. ... ... dna to RNA: a finger -shaped fold of amino acids ...

Y chromosome

... lies between the pseudoautosomal ... dna Genealogy: Extend your concept of family through dna testing. ... What Is Y-DNA ( Y chromosome ... 1141. ... Y chromosome . Human Y-chromosome dna haplogroups. Single-origin hypothesis ... ...

VNTR

... alleles are hypervariable regions of human dna that differ from each other in: ... VNTR stands ... may exist, each with ... If the fragments of dna containing the VNTR alleles are to be ... By using buoyant density gradient centrifugation, dna fragments with ... One type of minisatellites is ...

UvrA

... UvrB and forms a trimer which is able to detect dna ... ... acid sequence homology with the E. ... on its own binds preferentially to damaged dna (Seeberg and ... Incubation of substrate G1 ... UvrA (2)B complex allows dynamic recognition of dna damage. 18 ... Dimerization of Escherichia coli ...

Uracil

... main nucleobases found in the nucleic acids dna and RNA. ... Uracil (U), thymine (T), and ... adenosine through ... Substituted uracil in dna ... of the oxidized cytosine derivative, ... perform important functions ... uracil dna N-glycosylase activity. • protein binding ... ...
Other Contents
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(Date:9/18/2014)... tiny strands of nucleic acid that contain instructions for ... data, our DNA is copied into RNA molecules, which ... in our cells. , Several years ago, scientists ... other known RNAs, this molecule is circular, and was ... has been known about how they are produced. Moreover, ...
(Date:9/18/2014)... from several disciplines will be celebrated tonight at the ... in improving the health of premature infants and in ... The researchers, whose work was supported by the National ... former Atomic Energy Commission, will be honored at a ... A bipartisan group of Members of Congress will be ...
(Date:9/18/2014)... the ideal animal in which to study the genes ... into tens of thousands of freshwater streams and lakes ... adapt to the new environment. , Breeding studies between ... up one of the genes that controls tooth number, ... regulation in a freshwater population is associated with a ...
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