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diffraction in Medical News

Varian, Inc. Acquires Oxford Diffraction, Ltd.

... in solutions. "The acquisition of Oxford diffraction is key to Varian's goal of broadening its range ... Rogerson, President and CEO, Varian, Inc. "Oxford diffraction has experienced rapid growth since its formation ... particularly in Europe. Oxford diffraction products will now be distributed on a global ...

Measurement technique probes surface structure of gold nanocrystals

... in the nanocrystal, resulting in a complicated diffraction pattern made of speckles similar to what is seen ... is reflected by a surface. When deciphered, the diffraction pattern describes the structural arrangement and ... Zuo said. Nano-area coherent electron diffraction makes it possible for us to probe the surfaces of ...

University of Pittsburgh researchers crack code of 3-D structure in key metabolic protein

... intensity parallel X-rays to the protein crystals in order to collect the diffraction data necessary to determine the proteins atomic configuration. These ... Highly advanced computational techniques were then used to analyze the diffraction data and to uncover, through complex mathematical approaches, the atomic ...

Unique skeletal muscle design contributes to spine stability

... a unique packing design consisting of short fibers arranged within rods, and that these fibers are stiffer than any other in the body. Using laser diffraction methods that they developed to measure muscle internal properties during back surgery, they demonstrated that the multifidus' unique design serves a ...

Cell phones using lens-free imaging promise to improve health monitoring

... captures an image of the microparticles in the solution using a sensor array. Because red blood cells and other microparticles have a distinct diffraction pattern, or shadow image, they can be identified and counted virtually instantaneously by LUCAS using a custom-developed "decision algorithm" that ...

A glass apart

... network had been undertaken. Using ISIS to study the relationship between these atoms and the host silicate glass via techniques unique to neutron diffraction has enabled us to move forward with the programme. The key outcome of our experiments has been a full understanding, at the level of atomic ...

IUPUI scientists report first 3-D view of anti-cancer agent

... X-ray crystallography is a widely used analytical technique in which X-rays are directed through crystals and results are deduced from the pattern of diffraction of the X-rays. Although bleomycin has been studied for 40 years and much is known about the mechanism of action of bleomycin, without an accurate ...

Scientists solve structure of gene regulator that plays key role in cancer

... crystals containing the protein of interest. The three-dimensional structure of the crystallized protein is deduced by analyzing the pattern of x-ray diffraction caused by the arrangement of atoms in the protein crystal. Marmorstein and his colleagues spent years attempting to crystallize p300/CBP a ...

SAFC Pharma Expands Its Pharmorphix Solid State Chemistry Services

... The development includes office reorganization and will facilitate installation later this year of additional state-of-the-art spectroscopic and diffraction equipment. SAFC Pharma Vice President of Manufacturing and European Operations, Michael Harris commented, "As new drugs and the regulatory ...

Researchers solve first structure of a key to intact DNA inheritance

... on a tiny loop in an X-ray diffractor and X-rays are beamed through it. Bending around the lattice of atoms in the crystal, the X-rays produce a diffraction pattern, which can be seen as a dot pattern on a monitor. A state-of-the-art X-ray diffractor shoots a different angle of the crystallized protein ...

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diffraction in Medical Technology

New Insight Into the Controls on a Go-To Enzyme

... researchers first crystallize a protein to be studied. Then, they direct X-rays through the crystal and deduce the protein structure from the diffraction pattern of those X-rays. To overcome the crystallization bottleneck, a lengthy and unpredictable variable in X-ray crystallography, the investigators ...

St. Jude Study Gives New Insights Into How Cells Accessorize Their Proteins

... In this widely used technique, X-rays are directed through the crystal of a protein to be analyzed and its structure deduced from the pattern of diffraction of the X-rays. Comparison of the two structures revealed that, when NEDD8 attaches to cullin-RING, it dramatically modifies the conformation of the ...

New Australian Technology: Detecting Breast Cancer With Hair

... structure of their hair which is detected using a technique called X-ray diffraction. This change is seen as a ring superimposed on the normal X-ray diffraction pattern of hair. [See images on http://www.australiabio2008.com/FermiscanNMR.php ]. The research has been published in the prestigious scientific ...
diffraction in Medical Products

Ultra Q Nd: YAG Photodisruptor

Features:... Air breakdown: <2.8mJ* Mode structure: Fundamental, diffraction limited Spot size: 8 m Cone angle: 16 degrees ... Air breakdown: <2.8mJ* Mode structure: Fundamental, diffraction limited Spot size: 8 m Cone angle: 16 degrees ...
Company:Ellex (formerly Laserex)

Advia 1200 Chemistry System

Features:... Segmented tray for easy cuvette replacement. This advanced, high precision optical system combines with a unique incubation fluid and a concavity diffraction grating to assure superior precision and accuracy in clinical chemistry instrumentation. Reagent Storage Area Refrigerated storage for ...
Company:Siemens Medical Solutions Diagnostics

Ultra Q - SLT-upgradeable, Nd: YAG Photodisruptor

Features:... 4 ns Burst mode: 1, 2 and 3 pulses per shot, selectable at 20 s separation Air breakdown: <2.8mJ* Mode structure: Fundamental, diffraction limited Spot size: 8 m Cone angle: 16 degrees Posterior offset: 100 m - 350 m, continuously variable Repetition rate: 2.3 ...
Company:Ellex (formerly Laserex)

Ultra Q, Nd: YAG Photodisruptor

Features:... Pulse width: 4 ns Burst mode: 1, 2 and 3 pulses per shot, selectable at 20 s separation Air breakdown: <2.8mJ Mode structure: Fundamental, diffraction limited Spot size: 8 m Cone angle: 16 degrees Posterior offset: 100 m - 350 m, continuously variable Repetition rate: 2.3 Hz, single ...
Company:Ellex (formerly Laserex)

Advia 2400

Features:... - provide cost-effective workstation consolidation. Advanced, high-precision optical system combines our unique incubation fluid and concavity diffraction grating to assure superior performance - exceeding laboratory standards for precision and accuracy in clinical chemistry instrumentation. Automatic ...
Company:Siemens Medical Solutions Diagnostics

Advia 1650

Features:... consolidation. Advanced, high-precision optical system combines an elongated cuvette path length, our unique incubation fluid and concavity diffraction grating to assure superior performance - exceeding laboratory standards for precision and accuracy in clinical chemistry instrumentation. Automatic ...
Company:Siemens Medical Solutions Diagnostics
diffraction in Medical Dictionary

Chromosomes

... by which inherited characteristics are passed on. 1944 - DNA is first connected to the inheritance of traits. 1951 - The first sharp X-ray diffraction photographs of DNA are obtained. Normally, an infant inherits one pair of sex chromosomes -- one X from the mother and one X or one Y from the ...
diffraction in Biological News

Jet-propelled imaging for an ultrafast light source

... off the atoms and reveal once these complex diffraction patterns have been converted into a 3-D image by ... are the smallest protein nanocrystals from which diffraction patterns have ever been obtained, and the first ... that infer the orientation of the sample from the diffraction pattern itself, even when as few as four percent ...

Argonne scientists use lasers to align molecules

... when bombarded with x-rays. From the resulting diffraction pattern, a real-space image can be reconstructed. ... making it impossible to create a composite diffraction image, Argonne Physicist Robin Santra said. ... Source facility located at Argonne before x-ray diffraction can be done experimentally. ...

Unveiling the structure of microcrystals

... National de Recherche Scientifique used X-ray diffraction at the synchrotron to determine the structure of ... structure. Scientists use X-ray or neutron diffraction to study crystalline structure when the size of ... considered a powder. Scientists can apply powder diffraction to analyse such a material but this technique is ...

Eight ASU faculty elected as AAAS Fellows

... of Physics. He was cited by the AAAS for "distinguished contributions to diffraction physics, especially atomic-resolution electron microscopy, electron diffraction studies of the chemical bond and diffractive (lens-less) x-ray imaging." ...

Research about plant viruses could lead to new ways to improve crop yields

... of imaging techniques cryo-electron microscopy at Vanderbilt, X-ray diffraction at Argonne and scanning transmission electron microscopy (STEM) at ... figured out how to make good samples and analyzed them using X-ray diffraction and traditional electron microscopy, there were a number of ambiguities in ...

Structures of important plant viruses determined

... using a combination of complementary imaging techniques x-ray diffraction at DOE's Argonne National Laboratory, cryo-electron microscopy at ... even after we were able to do that, and analyze the structures using x-ray diffraction and traditional electron microscopy, there were a lot of ambiguities in ...

Synergy between biology and physics drives cell-imaging technology

... biologists have turned to physicists for help in breaking through this diffraction limit. The result has been the development in recent years of several ... and experimental tools common to physics that allow the physical diffraction limits of light to be broken. As the authors of the article explain, ...

Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy

... crystals with x-ray radiation. The atoms in the protein crystals cause the x-rays to diffract, and the scientists collect and analyze the pattern of diffraction to solve the atomic-level structure of the proteins. "The biggest challenge was to get enough protein to purify and make crystals from it," says ...

Synthesizing the most natural of all skin creams

... of just 10% each of lipid molecules and dead skin cells (corneocytes), so the exact composition of the mixture is important. For the lipids, X-ray diffraction measurements at the Dutch/Flemish DUBBLE beamline at the ESRF (European Synchrotron Radiation Facility) allowed the Leiden researchers to find the ...

Tension in the nanoworld

... of an Atomic Force Microscope (AFM), yielding nanoscale resolved images at visible, infrared and terahertz frequencies. The s-SNOM thus breaks the diffraction barrier throughout the electromagnetic spectrum and with its 20 nm resolving power matches the needs of modern nanoscience and technology. Now, ...

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diffraction in Biological Technology

Breaking barriers with nanoscale lasers

... nanometers. The limit is sometimes called the diffraction limit, a property associated with any wave, such ... says you can't make a laser smaller than this diffraction limit or smaller than 250 nanometers for a ... laser to sizes smaller than that required by the diffraction limit," Ning explains. "Eventually, we were able ...

New imaging technique reveals the atomic structure of nanocrystals

... the University of Illinois overcomes the limit of diffraction and can reveal the atomic structure of a single ... positions of atoms requires clues provided by the diffraction pattern. But quantum dots are so small, the clues provided by diffraction alone are not enough. By combining two sources ...

Super-resolution X-ray microscopy

... key feature makes it possible to record detailed diffraction patterns while the sample is raster-scanned ... only the total transmitted intensity. These diffraction data are then treated with an algorithm conceived ... that deals with the several tens of thousands of diffraction images and combines them into one ...

First step to converting solar energy using 'artificial leaf'

... antennae. They did this using a combination of solid state NMR and X-ray diffraction (see attachment). X-ray diffraction enabled them to determine the overall structure and NMR allowed them to ...

Denser, more powerful computer chips possible with plasmonic lenses that 'fly'

... which dramatically increases the cost of manufacturing. Also, light has a diffraction limit restricting how small it can be focused. Currently, the minimum ... The UC Berkeley researchers chose a different approach to overcome the diffraction limit of light. They took advantage of a well-known property of metals: ...

New Dual Wavelength X-ray Diffractometer From Oxford Diffraction, Now a Part of Varian, Inc., Allows Increased Throughput for Challenging Single Crystal Analyses

... molecules and proteins. The SuperNova(TM) is the first dual wavelength diffraction system to use entirely high intensity micro-source X-ray technology. It ... results even for the most challenging crystals. Single crystal X-ray diffraction is used to determine the structure of small molecules and proteins at high ...

UTSA/UT lead national nanoscience consortium

... future imaging applications and nanophotonic devices is impeded by light diffraction which prevents confinement of light in the regions smaller than half of its wavelength, said Chabanov. We have promising ideas how to circumvent the diffraction limit by utilizing polaritonic and plasmonic materials. This might enable ...

NYU physicists find way to explore microscopic systems through holographic video

... to a laser pointer. When an object is placed into path of the microscope's beam, the object scatters some of the beam's light into a complex diffraction pattern. The scattered light overlaps with the original beam to create an interference pattern reminiscent of overlapping ripples in a pool of water. ...

Nano measurement in the third dimension

... structure spacing on extensive lattice standards even in the range of 10 picometers - have been achieved and confirmed in comparison with optical diffraction measurements. The new measuring instrument is available for dimensional precision measurements with nm resolution on 3D micro and nano structures ...

Bilayer graphene gets a bandgap

... principle we could have used a tunable laser to measure the optical transmission, but the 1.4 beamline is very bright and can be focused down to the diffraction limit an important consideration when the graphene-flake target is so small," Wang says. "Also, compared to a laser, the beamline provides a wider ...
diffraction in Biological Products

dotLab System, Single Pump from Axela Biosensors

Description:... well-understood technologies: grating-based light diffraction and immobilized capture surfaces. This ... series of parallel lines that produces a specific diffraction pattern when illuminated with a laser. The ... to the assay spots, resulting in an increased diffraction signal. The dotLab System uses the intensity of ...
Company:Axela Biosensors

dotLab System, Dual Pump from Axela Biosensors

Description:... well-understood technologies: grating-based light diffraction and immobilized capture surfaces. This ... series of parallel lines that produces a specific diffraction pattern when illuminated with a laser. The ... to the assay spots, resulting in an increased diffraction signal. The dotLab System uses the intensity of ...
Company:Axela Biosensors
diffraction in Biological Definition

X-ray crystallography

... in which the pattern produced by the diffraction of x-rays through the closely spaced lattice ... Inorganic Structures X-ray diffraction finds frequent use in materials science because ... which are not yield some useful information in diffraction experiments. The pattern ...

DNA

... London , Maurice Wilkins and Rosalind Franklin were examining X-ray diffraction patterns of DNA fibers. Discovery that DNA is helical A key ... had deduced this structure from X-ray patterns. Even in the initial crude diffraction data from DNA, it was evident that the structure involved helices. But ...

Biochemistry

... then, biochemistry has advanced, especially since the mid- 20th century , with the development of new techniques such as chromatography , X-ray diffraction , NMR , radioisotopic labelling , electron microscopy and molecular dynamics simulations. These techniques allowed for the discovery and ...

Insulin

... in 1958. In 1967, after decades of work, Dorothy Crowfoot Hodgkin determined the spatial conformation of the molecule, by means of X-ray diffraction studies. She also was awarded a Nobel Prize. 1. Preproinsulin ( L eader, B chain, C chain, A chain); proinsulin consists of BCA, ...

James D. Watson

... to Copenhagen for postdoctoral work. In 1952 , he started at Cavendish Laboratory , where he met Francis Crick . Building on the X-ray diffraction research of Rosalind Franklin and Maurice Wilkins , they together deduced the double helix structure of DNA, which they published in the journal ...

Microscope

... lens magnifies by bending light (see refraction ). Optical microscopes are restricted in their ability to resolve features by a phenomenon called diffraction which, based on the numerical aperture (NA or A N ) of the optical system and the wavelengths of light used ( λ ), sets a ...

Photon

... relation with respect to momentum.) This is the formal reason why light is slower in media (such as glass) than in vacuum. (The reason for diffraction can be deduced from this by Huygens' principle .) Another way of phrasing it is to say that the photon, by being blended with the matter excitation ...

Optical spectrum

... , where spectroscopy is essential for analysing the properties of distant objects. Typically, astronomical spectroscopy utilises high-dispersion diffraction gratings to observe spectra at very high spectral resolutions. The first exoplanets to be discovered were found by analysing the doppler shift ...

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diffraction in Biological Dictionary

X-ray diffraction

... and intensities of ... X-ray powder diffraction (XRD) is a rapid analytical technique primarily used ... X-ray diffraction is based on constructive interference of monochromatic X-rays ... Single-crystal X-ray diffraction is a non-destructive analytical technique which ...

Quaternary structure

... forces ... Controlling Structure . Quaternary Structure . Complex ... Quaternary Structure ... Quaternary structure and amyloid. X-ray diffraction of Scrapie Prion. Interactive prion models ... Certainly, the quaternary structure has a modulating ... TUTORIAL ON PEPTIDE AND PROTEIN ...
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