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Dendritic in Medical News

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

... BP-GMAX-CD1, a novel pharmacologically regulated dendritic cell vaccine for the treatment of prostate ... genetically modifying autologous antigen-loaded dendritic cells to express an inducible costimulatory CD40 ... administration, these genetically modified dendritic cells are activated in draining lymph nodes by ...

Microscopic 'beads' could help create 'designer' immune cells that ignore transplanted organs

... suppressor of the immune response, straight to dendritic cells, which typically show the immune system ... are given right after a transplant, just as dendritic cells are giving the immune system a heads up to ... would be needed for just a few weeks, until the dendritic cells have learned instead to ignore it, Dr. ...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

... a potential ally, but the brain has few dendritic cells -- key sentries of the immune system that ... immune attack. Without the surveillance of dendritic cells, brain tumors go undetected and proliferate ... (the immune stimulatory cytokine Flt3L) attracts dendritic cells from bone marrow into the tumor while ...

Computer simulation captures immune response to flu

... before or vaccinated. T cells partner with dendritic cells to make careful decisions about which key ... will trigger a full-scale immune counterattack. dendritic cells roam the body, checking each particle they ... invader "label." Upon encountering an invader, a dendritic cell will "swallow it," cut it up, and carry the ...

Study reveals current multi-component vaccines may need reworking

... T cell, a white blood cell that partners with dendritic cells to make careful decisions about which ... attention. Upon encountering an invader, a dendritic cell will "swallow it," cut it up, and carry the ... complex (MHC} class II proteins inside the dendritic cells present peptides on the cell's surface for ...

Not just a long-distance relationship: Immune cells in skin fight off infection better than the rest

... immune response to viral infection - known as dendritic cells. "Dendritic cells are like police ... for the first time that a particular type of dendritic cells was responsible for triggering the immune ... diseases of the skin such as psoriasis, where dendritic cells trigger the immune system to attack the ...

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Dendritic in Medical Technology

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

... The study entitled "Phase II Trial of dendritic Cells Loaded with Antigens from Self-Renewing, ... a total of up to eight injections. The patient's dendritic cells were obtained from their peripheral blood ... (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... vaccines can activate and cause human immature dendritic cells from blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell ...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

... Talactoferrin is a novel targeted dendritic cell recruiter and activator (DCRA) being studied ... mediates its anti-cancer activity by targeting dendritic cells which play an important role in activating ... talactoferrin induces the recruitment of immature dendritic cells to the GALT and promotes their maturation. ...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

... Peregrine's PS-Targeting Antibodies Stimulate dendritic Cell Maturation, Inflammatory Cytokine and ... antibody PGN632 to promote the maturation of dendritic cells, important antigen-presenting cells of the ... system. In the in vitro studies, immature dendritic cells cultured in the presence of PGN632 ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... on Molecular and Cellular Biology Conference on dendritic Cells, March 29-April 3, 2009 in Banff, Alberta. ... on March 30th entitled MAb-Enhanced, Human dendritic Cell-Mediated Adaptive Immune Response to B. ... can enhance the killing of anthrax by human dendritic cells. Dr. Cross remarked, "These latest ...

Update of Long-Term Data on Brain Cancer Patients Receiving DCVax(R)-Brain Continues to Show Striking Improvements in Delay of Disease and Survival

... surgery as part of the current standard of care. dendritic cells drawn from a sample of the patient's blood ... weeks apart and then months apart. These dendritic cells are then able to mobilize the immune system ... The Company has two broad platform technologies: dendritic cell-based vaccines and therapeutic antibodies. ...

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Dendritic in Medical Definition

Thymocyte

... as classical T cells, a number of alternative cell lineages develop in the thymus, including gamma-delta T cells, Natural Killer T cells and lymphoid dendritic cells. References ^ Baldwin TA, Hogquist KA, Jameson SC, The fourth way? Harnessing aggressive tendencies in the thymus. “J ....
Dendritic in Medical Dictionary

Herpesvirus

... of the cornea (and conjunctiva ) due to herpesvirus type I; a characteristic finding on physical examination of the eye ( cornea ) is a dendritic pattern (crystalline or tree-like pattern). Virus infection , such as Epstein-Barr virus or human herpesvirus 6 Dysfunction in the immune ...

Histiocytosis

... by an abnormal increase in the number of certain immune cells called histiocyte cells. These include monocyte s, macrophage s, and dendritic cells. Histiocytosis Alternate Names : Pulmonary Histiocytosis X , Histiocytosis X , Eosinophil ic Granuloma, Non lipid ...

Keratitis

... of the cornea (and conjunctiva ) due to herpesvirus type I; a characteristic finding on physical examination of the eye ( cornea ) is a dendritic pattern (crystalline or tree-like pattern). Untreated, fungal keratitis can scar the cornea and cause permanent vision loss. What does ...

Vaccination

... Tassis A, et al.: Vaccination of patients with cutaneous T- cell lymphoma using intra nodal injection of autologous tumor -lysate- pulse d dendritic cells. Blood 102 (7): 2338-44, 2003. [PUBMED Abstract] ... Measles may well be the most serious communicable disease of childhood, and it is ...
Dendritic in Biological News

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... The study entitled "Phase II Trial of dendritic Cells Loaded with Antigens from Self-Renewing, ... a total of up to eight injections. The patient's dendritic cells were obtained from their peripheral blood ... (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable ...

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

... structure. Small knob-like features, called dendritic spines, that protrude from a neuron's branch-like ... protein is not essential for the formation of dendritic spines, but that it is needed for the proper ... the team found that OPHN1 is recruited to dendritic spines, where it locally regulates the actin ...

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

... antibody PGN632 to promote the maturation of dendritic cells, important antigen-presenting cells of the immune system. In the in vitro studies, immature dendritic cells cultured in the presence of PGN632 ... molecules that are indicative of mature dendritic cells and that assist in antigen presentation ...

New origin found for a critical immune response

... are induced by rare immune cells, called dendritic cells. When activated by infection or vaccination, the dendritic cells were thought to move from peripheral ... The Duke researchers found, however, that the dendritic cells that stimulate TH1 responses didn't come ...

Molecule that suppresses immune response under study in type 1 diabetes

... because they have a transient defect in their dendritic cells that hurts IDO expression. dendritic cells, which can express IDO, show antigens to ... of Immunology paper last year reported that when dendritic cells and IDO are depleted in the mouse, the ...

Immune cells reveal fancy footwork

... Suzanne van Helden discovered that before dendritic cells move to the lymph nodes they lose their ... This helps them to move much faster. Immature dendritic cells patrol the tissues in search of antigens. ... maturation process. During this maturation the dendritic cells migrate to the lymph nodes to activate T ...

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Dendritic in Biological Technology

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

... its breast cancer trial has begun to receive its dendritic cell therapy. QI is currently ... The clinical trials involve the use of dendritic cell therapy using the oncofetal antigen ("OFA"), ... is designed around the use of QI's proprietary dendritic cell therapy, which employs OFA to recruit the ...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell ... to directly mimic cell/cell interactions on the dendritic and T-cell surface with synthetic peptides. The ....

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... the L.E.A.P.S. vaccine act and stimulate human dendritic cells in man in a similar manner as seen to isolated murine and human dendritic cells ex vivo and in vivo in the mouse. dendritic cells direct the subsequent immune response to a ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell ... may thus open a whole new way of maturing dendritic cell vaccines for infectious diseases such as ...

Immunotherapy-Based Provisional Patents Mark Significant Discovery

... using the body's own immune cells, i.e., the dendritic cells, to recognize OFA/iLRP as a foreign protein ... discovery of these sequences, QI believes that dendritic cell recognition of the foreign cancer protein ... create immunity against cancer without the use of dendritic cells. The second patent relates to ...

Agennix Receives Special Protocol Assessment Approval from FDA for the Pivotal Trial of Talactoferrin Alfa in First-Line Non-Small Cell Lung Cancer

... About Talactoferrin Alfa Talactoferrin, a novel dendritic cell activator (DCA), is a unique recombinant ... in the body. It acts through a novel mechanism of dendritic cell recruitment and activation. Following oral ... Patches, where it recruits circulating immature dendritic cells bearing tumor antigens to the GALT ...
Dendritic in Biological Products

UCB MoDC Cell Chip-IHC from 3H Biomedical AB

Description:... Monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood dendritic ...
Company:3H Biomedical AB

PDC Cell Chip-IHC from 3H Biomedical AB

Description:... Human plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and ...
Company:3H Biomedical AB

UCB PDC Cell Chip-IHC from 3H Biomedical AB

Description:... Plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood dendritic ...
Company:3H Biomedical AB

MoDC Cell Chip-IHC from 3H Biomedical AB

Description:... Human monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and ...
Company:3H Biomedical AB

EPC Cell Chip-IHC from 3H Biomedical AB

Description:... Human endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood dendritic Cells and ...
Company:3H Biomedical AB

Mouse Anti-Human DEP-1 / CD148 Monoclonal Antibody, Fluorescein Conjugated, Clone 143-41 from R&D Systems

Description:... Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, Monocyte Markers, Phosphatases & Regulators, Other dendritic Cell ...
Company:R&D Systems
Dendritic in Biological Definition

Apoptosis

... and published in Science Online in December, 2001. Albert described how dendritic Cells, a type of antigen-presenting cells, phagocytose (that is, engulf) apoptotic tumor cells. Upon maturation, these dendritic cells present antigen (derived from the apoptotic corpses) to killer T ...

Immune system

... cells (APCs). A major category of APCs involved in T cell activation, the dendritic cells , are part of the innate immune system. Activation occurs when a DC ... by T cells that are all belonging to the adaptive immune system. But the dendritic cells are often directly activated by engaging their toll like receptors ...

Dendrite

... from separate branches or "arbors." The term "dendrite" comes from the Greek word dendron , meaning "tree". Compare : axon See also : dendritic spine ...

Major histocompatibility complex

... a risk of contagion for neighboring cells. Mhc Class II molecules are found only on a few specialized cell types, including macrophages , dendritic cells , activated T cells , and B cells , which may be referred to collectively as "antigen-presenting cells" (APCs). Class II molecules are also ...

Neuron

... with many target cells. The dendrite , a short, branching arbor of cellular extensions. Each neuron has very many dendrites with profuse dendritic branches. These structures form the main information receiving network for the neuron. Axon and dendrites alike are typically only about a ...

Synapse

... Integration of synaptic inputs 5 Detailed properties and regulation 6 References Anatomy At a prototypical synapse, such as a dendritic spine , a mushroom-shaped bud projects from each of two cells and the caps of these buds press flat against one another. At this interface, the ...

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Dendritic in Biological Dictionary

Dendritic cell

... 4 dendritic cells and cytokines. 5 Relationship to HIV, allergy, and autoimmune diseases ... Plasmacytoid dendritic cell (pDC) ... Dendrites are the ... project. ... The key function of dendritic cells is that of "presenting of antigen": ...

Purkinje fibers

... cells have two action potentials: Climbing fiber responses (CFRs) and ... action of a subset of parallel fiber synapses on Purkinje cell dendritic spines. ... ...

Protocells

... thermal proteins ... attributes of life), and metaprotocells ( protocells that can use light to ... Photographs of Protocells . Formation of dendritic and free protocells on the surface of abiotic thermal ... Protocells are 3 um in diameter. ... Shop for Protocells - Books at Shop.com. ...

Monocytes

... cell, part of the human body's immune system. Monocytes have two main functions in the immune system: (1) replenish resident macrophages and dendritic cells under normal states, and (2) ... Monocytes develop in the bone marrow and reach maturity in the blood. ... Monocytes ingest ...

Immunology

... classic features ... Nature Immunology is a multidisciplinary journal that publishes papers of the ... Postdoctoral Position- Immunology of dendritic Cells ... Monthly review journal publishes peer-reviewed articles on immunology , including infection and immunity. PART ONE: IMMUNOLOGY . ...

Dendrites

... ... Although the brain's axons and dendrites are neighbors, they differ in many ... abnormally short dendrites , so Jan's group named the genes dendritic arbor ... ...

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Other Contents
(Date:8/20/2014)... at the Universities of Manchester and Auckland suggest that both ... mechanism. , The findings, published today in the ... or type-1 diabetes and type-2 diabetes are both caused by ... , The results, based on 20 years, work ... both be slowed down and potentially reversed by medicines that ...
(Date:8/20/2014)... VA (PRWEB) August 20, 2014 ... nation’s leading nonprofit authority on the use of ... exchange, announced the full agenda for its annual ... Health IT Efficiency. WEDI-Con 2014 will take place ... October 20-23, 2014, attracting a diverse cross-section of ...
(Date:8/20/2014)... The National Association of Hispanic ... Science Education Partnership Award (SEPA) grant from the ... project with the Hispanic Communications Network (HCN) entitled ... collaborative NIH R25 program has been established to ... among health professionals by recruiting and interviewing bilingual ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 Attendees of ... a sneak peak at Los Angeles’ first multi-faceted food ... tour of a blossoming 1.5-acre high school campus urban ... shipping container farm in the L.A. Art District. , ... of sustainable urban agriculture, will kick off Seedstock’s “Reintegrating ...
(Date:8/20/2014)... Charlotte, North Carolina (PRWEB) August 20, 2014 ... BBC , findings from a University College London (UCL) ... drastically disagreed on what method of brushing teeth was ... worldwide found that six different tooth-brushing techniques were frequently ... At the Charlotte Center for Cosmetic Dentistry, experienced ...
Breaking Medicine News(10 mins):Health News:Scientists show type-1 and type-2 diabetes are caused by same underlying mechanism 2Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 2Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 3Health News:National Association of Hispanic Nurses (NAHN) Receives Five-Year Federal Grant from the National Institutes of Health (NIH) 2Health News:National Association of Hispanic Nurses (NAHN) Receives Five-Year Federal Grant from the National Institutes of Health (NIH) 3Health News:Seedstock Sustainable Agriculture Conference’s Urban Farm Field Trip to Offer First Look at Los Angeles’ Premier Food Business Incubator 2Health News:Seedstock Sustainable Agriculture Conference’s Urban Farm Field Trip to Offer First Look at Los Angeles’ Premier Food Business Incubator 3Health News:Ending Confusion About the Best Way to Brush Teeth 2Health News:Ending Confusion About the Best Way to Brush Teeth 3
(Date:8/19/2014)... many parts of the world, leprosy and tuberculosis ... cases of leprosy per year, with nearly all ... currently available century-old vaccine Bacille Calmette-Guerin, or BCG, ... leprosy, so a more potent vaccine is needed ... found a stronger weapon against both diseases., In ...
(Date:8/19/2014)... with neonatal abstinence syndrome (NAS) secondary to in-utero ... through withdrawal than others, but the underlying reasons ... (when genes are turned on or off) changes ... at Boston University School of Medicine (BUSM) and ... its kind study to identify some of these ...
(Date:8/19/2014)... Science Center at San Antonio and The University of ... of more than $750,000 in grants through the San ... in 2003, SALSI is a model of how a ... center join forces for greater research and graduate education. ... focus on public health issues and diseases of global ...
Breaking Biology News(10 mins):New vaccine shows promise as stronger weapon against both tuberculosis and leprosy 2In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome 2San Antonio Life Sciences Institute awards $750,000 to innovators 2San Antonio Life Sciences Institute awards $750,000 to innovators 3
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