Viral Infection Might Trigger High Blood Pressure

... animal studies indicate. Mice infected with cytomegalovirus (CMV) were more likely to develop not only high ... a CMV vaccine. "It is virtually certain that cytomegalovirus infection makes at least some contribution to ... disease in people," Schleiss said. "Obviously, cytomegalovirus is not the whole picture. There are other issues, ...

ViroPharma Reports Results of Phase 3 Clinical Trial for Maribavir in Bone Marrow Transplant Patients

... drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, ... to current anti-CMV therapies. About cytomegalovirus CMV is a member of the herpes virus group, ... drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma ...

Cell death from cytomegalovirus may bring new life to treatment of retinal disease

... likely the body's well-intended effort to stop cytomegalovirus retinitis. "We can try to infect certain cells ... looking at mechanisms of retinal damage during cytomegalovirus infection," Dr. Atherton said. Tools include a ... blood and semen, it's most typically latent. cytomegalovirus retinitis' last big resurrection came with the ...

Also in the March 24 JNCI

... Human cytomegalovirus Stimulates Telomerase Activity in Tissue Culture Cells Infection with human cytomegalovirus (HCMV) triggers expression of the telomerase reverse transcriptase (hTERT) ...

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

... changes in metabolic flux in human cells as they become infected by human cytomegalovirus (HCMV), an enveloped virus of the b-herpes family that infects most human ... severe disease in those with weakened immune systems. Researchers chose cytomegalovirus for experiments because it serves as an excellent model for processes at ...

ViroPharma Receives European Orphan Drug Designation for CAMVIA(TM)

... has granted orphan drug designation for CAMVIA for the prevention of cytomegalovirus (CMV) disease in patients with impaired cell-mediated immunity. The ... of CMV that are resistant to commonly used anti-CMV drugs. About cytomegalovirus CMV is a member of the herpes virus group, which includes the ...

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Cytomegalovirus in Medical Technology

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

... evaluating maribavir used as prophylaxis against cytomegalovirus (CMV) disease in liver transplant patients has ... drug with a unique mechanism of action against cytomegalovirus and a favorable clinical safety profile to date, ... to current anti-CMV therapies. About cytomegalovirus CMV is a member of the herpes virus group, ...

Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial

... in a Phase 2 trial of its therapeutic DNA vaccine designed to prevent cytomegalovirus (CMV) reactivation and disease in immunosuppressed stem cell transplant ... these forward-looking statements. (1) Avetisyan G, et al. Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of ...

Promise of Vical's CMV Vaccine Noted by Independent Experts

... issue of The Journal of Infectious Diseases (JID), independent experts on cytomegalovirus (CMV) said the vaccine under development by Vical Incorporated (Nasdaq: ... to update these forward-looking statements. (1) Go V, Pollard RB. A cytomegalovirus Vaccine for Transplantation: Are We Closer? J Infect Dis 2008; ( ...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... the package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

FDA Grants Priority Review of a Supplemental Biologics License Application for Cinryze(TM) C1 Inhibitor (Human) as Treatment for Acute Attacks of Hereditary Angioedema (HAE)

... the package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

Cytomegalovirus in Medical Products

ImmunoDOT Mono M Test

Description:... is a qualitative enzyme immunoassay (EIA) that detects IgM antibodies to Paul-Bunnell heterophil, Epstein-Barr virus capsid antigen (EBV-VCA), and cytomegalovirus (CMV). When used in conjunction with Mono-G Test, it is an aid in the serodiagnosis of infectious (EBV) mononucleosis and presumptive serodiagnosis ...
Company:GenBio

ImmunoDOT Mono G Test

Description:... enzyme immunoassay (EIA) that detects IgG antibodies to Epstein-Barr virus capsid antigen (EBV-VCA), Epstein-Barr early nuclear antigen (EBV-EBNA), cytomegalovirus (CMV), and Toxoplasma. When used in conjunction with Mono-M Test it is an aid in the serodiagnosis of infectious (EBV) mononucleosis and presumptive ...
Company:GenBio

ImmunoDOT TORCH Test

Description:... TORCH Test is an enzyme immunoassay (EIA) procedure intended for determining the presence of antibodies to Toxoplasma gondii, rubella virus, cytomegalovirus and herpes simplex virus in serum and heparinized whole blood to indicate previous or current infection by these ....
Company:GenBio

PK7200® Automated Microplate System

Description:... agglutination technology. Its is a fully automated blood testing system for donor ABO/Rh testing. PK7200 also handles weak D as well as syphilis and cytomegalovirus antibody detection. The Automated Microplate System delivers the very latest technology along with the proven reliability that for the past ...
Company:Olympus America Diagnostics

Viroclear ToRCH

Description:... to Toxoplasma gondii (TOXO IgG and TOXO IgM), IgG and IgM antibodies to rubella virus (rubella IgG and rubella IgM), IgG and IgM antibodies to cytomegalovirus (CMV IgG and IgM), and IgG and IgM antibodies to herpes simplex virus types 1 and 2 (HSV-1 IgG, HSV-1 IgM, HSV-2 IgG and HSV-2 ....
Company:Blackhawk BioSystems, Inc.

Virotrol® ToRCH-M

Description:... to Toxoplasma gondii (TOXO IgG and TOXO IgM), IgG and IgM antibodies to rubella virus (rubella IgG and rubella IgM), IgG and IgM antibodies to cytomegalovirus (CMV IgG and CMV IgM), and IgG antibodies to herpes simplex virus types 1 and 2 (HSV-1 IgG and HSV-2 ....
Company:Blackhawk BioSystems, Inc.

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Cytomegalovirus in Medical Dictionary

Cytomegalovirus

... cytomegalovirus (CMV) is a virus related to the herpes ... is incurable and is a life-time infection . cytomegalovirus (CMV) is a common viral infection related to ... illness - and doesn't require treatment . cytomegalovirus Dr Rob Hicks Few people have heard of ...

Epstein-barr Virus

... Epstein-Barr virus (EBV) or, more rarely, the cytomegalovirus (CMV), is the cause of this infection . ... EBV. AIDS patients are highly vulnerable to cytomegalovirus (CMV), herpes simplex virus (HSV), ... virus , but other virus es, such as cytomegalovirus (CMV), can also cause mono . Mono is most ...

German measles

... virus that causes serious illness in newborns ( cytomegalovirus ). A skin disease that causes sores, usually ... , the virus that causes German measles \ \ cytomegalovirus , ... Several maternal- fetal infections ... German measles , now rare in the United States), cytomegalovirus (CMV), and toxoplasmosis . It is considered ...

Herpesvirus

... which are associated with human disease . See cytomegalovirus ; Epstein-Barr virus ; herpes simplex ; herpes ... es (HSV), including HSV-6, HSV-2, HSV-7, and cytomegalovirus , have been detected in women with cervical ... can also be caused by other organ isms such as cytomegalovirus (CMV). Both virus es are members of the ...

Pneumocystis Carinii

... pneumocystis carinii pneumonia candidiasis cytomegalovirus infection toxoplasmosis cryptosporidium ... include Candida fungus , cryptococcosis, cytomegalovirus , herpes simplex virus , Mycobacterium avium ... cancer . Foscarnet and ganciclovir to treat cytomegalovirus (CMV) eye infections Fluconazole to treat ...

Retinitis

... in the UK are affected. CMV Retinitis cytomegalovirus is a large herpes -type virus commonly found ... of the retina , linked in AIDS to cytomegalovirus infection . Untreated, it can lead to ... drug for the treatment of AIDS -related cytomegalovirus (CMV) retinitis . Retinitis pigmentosis, a ...

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Cytomegalovirus in Biological News

UCSF researchers identify new drug target for Kaposi's sarcoma

... "All known herpes virus proteases are structurally similar," Craik explained. "The inhibitor we found knocks out not only KS, but also the cytomegalovirus protease, so the site we've identified here could be a target for a broad-acting inhibitor against the entire viral family." To their knowledge, ...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

... program of the U.S. Defense Threat Reduction Agency (DTRA). Bavituximab and other anti-PS antibodies are also being studied preclinically in HIV, cytomegalovirus (CMV) and other serious viral infections. "Based on these findings, anti-PS antibodies such as bavituximab may represent a completely new class ...

Caltech biologists spy on the secret inner life of a cell

... laboratory studies how the immune system recognizes its targets, work that is offering insight into the processes by which viruses like HIV and human cytomegalovirus invade cells and cause disease. The electron tomography images revealed that the FcRn/antibody complexes were collected within cells inside large ...

Virus weaves itself into the DNA transferred from parents to babies

... it produces any developmental or immune system problems. Some congenital infections can cause serious problems in fetuses. If a mother contracts cytomegalovirus (CMV) while pregnant, her fetus is at risk of hearing or vision loss, developmental disabilities and problems with the lungs, liver and spleen. Some ...

CMV infections affect more than just patients with compromised immune systems, researchers find

... An infection due to a virus called cytomegalovirus (CMV), which most commonly affects people with compromised immune systems, can also affect hospital intensive-care patients who have no immune-system ...

A viral cloaking device

... in a continual dance for survival--viruses ever seek new ways to evade detection, and our immune system devises new methods to hunt them down. Human cytomegalovirus (HCMV), says Bjorkman, Caltech's Delbrck Professor of Biology and a Howard Hughes Medical Institute (HHMI) Investigator, "is the definition of a ...

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Cytomegalovirus in Biological Technology

ViroPharma Incorporated Reports Fourth Quarter and Full Year 2008 Financial Results

... maribavir clinical development program for prophylaxis against cytomegalovirus disease in transplant patients based on the preliminary analysis of phase ... currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile. ViroPharma routinely posts information, ...

AlphaVax Announces New CMV Advisory Board

... TRIANGLE PARK, N.C., Jan. 30 /PRNewswire/ -- AlphaVax has assembled its cytomegalovirus (CMV) Advisory Board to provide expertise and advice as the company moves ... to have these distinguished researchers and clinicians in the field of cytomegalovirus provide their perspectives on advancing an alphavirus vectored CMV ....

Chimerix, Inc. Appoints Kenneth I. Moch Chief Operating Officer

... with smallpox vaccination, as well as for the treatment of infections that cause morbidity and mortality in immunocompromised patients such as cytomegalovirus (CMV) and BK virus. Chimerix's pipeline includes an anti-HIV drug, CMX157, in late-stage preclinical studies. Chimerix is also advancing programs ...

ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

ViroPharma to Present at Two June Healthcare Conferences

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

ViroPharma Incorporated Honored by the National Organization for Rare Disorders

... package inserts at http://www.viropharma.com/Products.aspx ). ViroPharma currently focuses its drug development activities in diseases including cytomegalovirus (CMV), HAE and C. difficile . ViroPharma routinely posts information, including press releases, which may be important to investors in the ...

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Cytomegalovirus in Biological Products

LIGHT DIAGNOSTICS™ CMV pp65 Dextran Leukocyte Separation Kit, included in kit #3247 from CHEMICON

Description:... The Light Diagnostics cytomegalovirus (CMV) pp65 Antigenemia Immunofluorescence Assay (IFA) is intended for the qualitative identification of lower matrix protein pp65 of CMV in isolated ...
Company:CHEMICON

Cytomegalovirus in Biological Dictionary

Nuclear lamina

... the ... Given that the nuclear lamina potentially excludes nucleocapsids from ... Remodelling of the nuclear lamina during human cytomegalovirus infection: role ... The main components of the nuclear lamina are the lamins, which, based on their ... The nuclear lamina represents a ...