Case Western Reserve awarded nearly $1 million from Research to Prevent Blindness Foundation
... talented basic scientists to devote their careers to eye research. Irina A. Pikuleva, Ph.D. Dr. Pikuleva, a national leader in studies of cytochromes P450, the key enzymes involved in cholesterol elimination, was recruited to Case Western Reserve to apply her expertise along with the newly-funded ...Alcohol consumption and polymorphisms of cytochromes P4502E1 are high risks for ESCC
... studies have demonstrated that drinking alcoholic beverages is causally related to the development of ESCC. The genetic polymorphisms of cytochromes P4502E1 (CYP2E1), aldehyde dehydrogenase-2 (ALDH2) and alcohol dehydrogenase-1B (ADH1B; previously called ADH2) affect the metabolism of alcohol. ...NIH grants enable energy studies
... of juniors and seniors, are related to bioenergy conversion, whereby the students are cloning and knocking out genes for many cytochromes. These cytochromes are potentially involved in bioelectricity generation. This work also is linked to the biogenesis pathways, and began as collaboration between the ...Need oxygen? Cells know how to spend and save
... In the mitochondria, the tiny powerhouses found in every cell, energy is produced by passing electrons through a series of relay stations called cytochromes until they eventually join with oxygen to form water. This final step is directed by the protein cytochrome coxidase, or COX for short. If electrons ...Anti-cancer Compound In Beer Gaining Interest
... cancer preventive properties, scientists say. It, and other related flavonoid compounds found in hops, inhibit a family of enzymes, commonly called cytochromes P450 that can activate the cancer process. It also induces activity in a "quinone reductase" process that helps the body detoxify carcinogens. And it ...