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Creatinine in Medical News

Kidney Function Test May Not Be Cost-Effective

... molecule creatinine, resulting in higher serum creatinine levels. In this study, Dr. Harold Feldman, of ... Medicine, and colleagues compared eGFR with serum creatinine reporting alone, another commonly used measure of ... cases of end-stage kidney disease than serum creatinine reporting. While measuring eGFR would likely ...

Exjade(R) Benefits Chronically Transfused Patients by Significantly Reducing Toxic Iron That Can Damage Key Organs, According to Landmark Trial

... Give particular attention to monitoring serum creatinine in patients who: are at increased risk of ... depress renal function. Assess serum creatinine in duplicate before initiating therapy to ... due to variations in measurements. Monitor serum creatinine monthly thereafter. In patients with additional ...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

... >=50mL/min, approximately corresponding to serum creatinine levels of <=1.7mg/dL in men and <=1.5mg/dL ... approximately corresponding to serum creatinine levels of >1.7 to <=3.0mg/dL in men and >1.5 ... approximately corresponding to serum creatinine levels of >3.0mg/dL in men and >2.5mg/dL in ...

Novel Diagnostic Marker for Acute Kidney Injury Previewed at Abbott-Sponsored Scientific Workshop

... measure the ability of the kidneys to filter creatinine into the urine -- is unable to identify the ... medicine, Yale University Medical School. "Serum creatinine testing is inadequate. It is a non-specific ... the children developed AKI, based on results of creatinine tests reported two to three days after surgery. ...

Kidney Trouble Short-Lived in Most Liver Transplant Patients

... between March 2000 and August 2005, and had serum creatinine of at least 1.5 mg/dl for at least two weeks ... kidney problems. Diabetes and serum creatinine level at the time of transplant were other major ... rare among patients whose pre-transplant serum creatinine was elevated for less than 12 weeks. The ...

Muscle Mass May Not Explain High Creatinine in Black Kidney Patients

... advanced kidney disease have higher levels of creatinine than white patients, says a U.S. study that challenges a widely held belief. creatinine is a standard indicator of kidney function. A higher level of creatinine is generally a sign of lower kidney function. ...

Creatinine increase in elderly means increased renal disease, mortality

... BIRMINGHAM, Ala. -- Even small increases in serum creatinine levels during hospitalization raise the risk of ... M.D, is the first systematic description of creatinine increase and longer-term end stage renal disease ... Previous studies have shown that a rise in serum creatinine level of 0.3 milligrams per deciliter or more ...

Study: Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys

... want to ask their doctors to test their blood creatinine levels before sending them for a scan. creatinine levels go up when the kidneys arent operating ... is defined as a 25 percent or greater increase in creatinine within 48 hours of receiving contrast agent. The ...

Chronic kidney disease rises while most people with the condition remain unaware

... with a formula that considers the amount of creatinine in a blood sample, along with age, gender and African American race, which can affect results. creatinine is a waste product created by normal breakdown of ... cells during activity. When kidneys are ailing, creatinine builds up in the blood. A small sample of urine ...

AZOR(TM) Receives FDA Approval for Treatment of High Blood Pressure

... artery stenosis, increases in serum creatinine or blood urea nitrogen (BUN) have been reported. ... artery stenosis, increases in serum creatinine or blood urea nitrogen (BUN) have been reported. ... prescribing information for AZOR and Benicar * creatinine clearance <40mL/min. (1) ...

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Creatinine in Medical Technology

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... (less than or equal to 35 mg albumin/g urine creatinine for women and less than or equal to 25 mg albumin/g urine creatinine for men) at the outset, and who have at least one ... renal artery stenosis, increases in serum creatinine or blood urea nitrogen (BUN) have been reported. ...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

... of Zometa are recommended based on calculated creatinine clearance. Before each Zometa dose, serum creatinine should be measured and treatment should be withheld for renal deterioration until serum creatinine has returned to within 10% of the baseline value. ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... Give particular attention to monitoring serum creatinine in patients who: are at increased risk of ... depress renal function. Assess serum creatinine in duplicate before initiating therapy to ... due to variations in measurements. Monitor serum creatinine monthly thereafter. In patients with additional ...

Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation

... vs. 8%, mainly rash) and a mild increase in blood creatinine (4.7% vs. 1%) due to inhibition of tubular secretion of creatinine in the kidneys. The mechanism of blood creatinine increase was well defined in a separate study ...

Landmark ATHENA Study Findings With Multaq(R) (dronedarone) Shows 24% Reduction In Cardiovascular Hospitalization or Death in Patients With Atrial Fibrillation

... (10% vs. 8%, mainly rash) and increased blood creatinine (4.7% vs. 1%). The mechanism of blood creatinine increase (inhibition of creatinine secretion at the renal tubular level) was well ...

Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer

... 18 years of age. Renal impairment: Patients with creatinine clearance > or = 45 ml/min require no dose ... for all patients. Use in patients with creatinine clearance below 45 ml/min is not recommended. See ... in delayed clearance of pemetrexed. If necessary, creatinine clearance should be closely monitored. Patients ...

Living Donor Kidney Transplants Using Alemtuzumab Pre-Conditioning and Tacrolimus Monotherapy: Long-Term Safety and Efficacy

... were 98.0%, 90.5%, 87.5%, 80.1%, and 73.7%, respectively. The mean (+/-SD) creatinine (mg/dL) after 1, 2, 3, and 4 years were 1.43 (+/-0.55), 1.58 (+/-1.13), ... points were 97.1%, 89.6%, 85.2%, and 77.5%, respectively. The mean (+/-SD) creatinine (mg/dL) after 1, 2 and 3 years were 1.42 (+/-0.61), 1.56 (+/-0.96) and ...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

... (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy ... pneumonia, interstitial pneumonitis, hepatic failure, increases in serum creatinine in patients with renal insufficiency, acute hypersensitivity (angioedema, ...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

... (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy ... pneumonia, interstitial pneumonitis, hepatic failure, increases in serum creatinine in patients with renal insufficiency, acute hypersensitivity (angioedema, ...

FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C

... (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should ... pneumonia, interstitial pneumonitis, hepatic failure, increases in serum creatinine in patients with renal insufficiency, acute hypersensitivity (angioedema, ...

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Creatinine in Medical Products

Infinity Creatinine

Description:... The Infinity creatinine single liquid stable reagent offers the laboratory all the convenience of ... quick result turnaround time. The proprietary technology of the Infinity creatinine reagent provides a long shelf life that will minimize reagent ....
Company:ThermoFisher Scientific

Creatinine (Liquid)

Description:... For the quantitative in vitro determination of creatinine in serum, plasma or ....
Company:Randox Laboratories Ltd.

The Dropper Plus Point-of-Care Urine Dipstick Control

Description:... stability eliminates storage problems and provides maximum portability ideal for sites without refrigeration. A new feature is the addition of creatinine and microalbumin. Values are provided for all analytes; qualitative results for hCG for early pregnancy detection test methods are included. This ...
Company:Quantimetrix Corporation

DipandSpin Combination Urine Dipstick and Microscopics Control

Description:... bottle with three controls. DipandSpin is a combination product for dipstick, hCG, and microscopics quality control. A new feature is the addition of creatinine and microalbumin. Values are provided for microscopic measurements as well as for all analytes; qualitative results for hCG are also included. ...
Company:Quantimetrix Corporation

The Dropper Urine Dipstick Control

Description:... the control directly onto the dipstick with a plastic dropper tip designed for easy dispensing and maximum use. A new feature is the addition of creatinine and microalbumin. Assay values are supplied for all analytes; qualitative results for hCG for early pregnancy detection test methods are also ...
Company:Quantimetrix Corporation

The Dipper Urine Dipstick Control

Description:... readings of urine dipsticks by immersing the dipstick into the control the same way a patient sample is tested. A new feature is the addition of creatinine and microalbumin. Values are provided for all analytes; includes qualitative results for hCG for early pregnancy detection test methods. The Dipper ...
Company:Quantimetrix Corporation

Clinitek® Microalbumin Reagent Strips

Description:... dip-and-read urinalysis product available for the Clinitek® 50 and Clinitek® 100 systems. Clinitek® Microalbumin Strips provide albumin, creatinine and albumin-to-creatinine ratio results in one minute. The Clinitek® Microalbumin product is useful to test for microalbuminuria in patients with ...
Company:Siemens Medical Solutions Diagnostics

Nova 16 Electrolyte/Chemistry Analyzer

Description:... to perform a Chem 7 panel plus hematocrit on a whole blood sample. Its test panel -- including sodium, potassium, chloride, TCO 2 , glucose, BUN, and creatinine -- represents the most commonly ordered stat or routine panel in virtually every hospital. The addition of hematocrit provides valuable clinical ...
Company:Nova Biomedical

Clinitek Microalbumin Reagent Strips

Description:... Clinitek Microalbumin Strips provide albumin, creatinine and albumin-to-creatinine ratio results in one minute. The Clinitek Microalbumin product is useful to test for microalbuminuria in patients with ...
Company:Siemens Medical Solutions Diagnostics

DCA 2000+ Analyzer

Description:... method, as recommended by the ADA** Microalbuminuria Testing Microalbuminuria cartridge provides results for both albumin and creatinine Instrument automatically calculates the A:C ratio, so you can use any specimen at any time ...
Company:Siemens Medical Solutions Diagnostics

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Creatinine in Medical Dictionary

BUN

... Results Mean? BUN - ... BUN increase creatinine increase Arterial blood gas analysis showing ... of oxygen in the blood ) ... High BUN -to- creatinine ratio. High BUN -to- creatinine ratios occur with sudden ( acute ) kidney ...

Creatinine clearance

... creatinine clearance Definition: The creatinine clearance test compares the level of creatinine in urine with the ...

Creatinine

... creatinine - serum The test is performed to evaluate kidney function. If kidney function is abnormal, creatinine levels will increase in the blood , due to decreased excretion of creatinine in the urine . ...

Serum

... blood serum are albumin and globulin. creatinine - serum Powered by: This information is ... urine ) testing, especially a baseline serum creatinine level, which provides a gross estimation of ... filtration rate calculated using your serum creatinine measurement) and have a low Hct, the most likely ...

Urea nitrogen

... (yoo-REE-ter) ... Blood urea nitrogen -to- creatinine ratio ( BUN : creatinine ) The levels of blood creatinine and blood urea nitrogen ( BUN ) can be used ...

Urinalysis

... casts, or other abnormalities. The BUN and creatinine may rise rapidly. The creatinine clearance decreases. Urinalysis is the ... , protein , and other abnormalities. BUN , creatinine are elevated. Red blood cell count, ...

Craniotomy

... , UMHS discharge instructions Creatine kinase (CK) total test creatinine clearance test creatinine , blood ( serum ) test for Crohn's disease * Crutches, how to use - ...

Polyneuropathy

... ... CPID: See Chronic Idiopathic Demyelinating Polyneuropathy . creatinine : A protein found in muscle s and blood and excreted by the kidney s in the urine . creatinine levels in the blood or urine provide a measure of kidney function. ...

Values

... one of the statin family. The new GFR calculation uses the patient's creatinine measurement along with weight, age, and values assigned for sex and ... labor atories may calculate GFR at the same time they measure and report creatinine values . Four reference values are included in the DRIs. Estimated ...

Acromegaly

... in acromegaly ; (2) suppression of severe diarrhea and flushing associated with malignant carcinoid syndrome ; ... cause increased blood creatinine levels include blockage of the urinary tract (such as by a kidney stone), heart failure , dehydration , excessive blood loss that causes ...

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Creatinine in Biological News

Updated formula measures kidney function more accurately

... waste products excreted by the kidney, such as creatinine and blood urea nitrogen (BUN), and different ... by the study is based on height and gender, serum creatinine and BUN, and cystatin C a ubiquitous protein ... sample of blood will determine the level of serum creatinine and BUN, while a slightly more complicated method ...

Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines

... "If your total score from the SCORED test is 4 or higher, it doesn't mean you have CKD, but we strongly recommend further blood testing for creatinine (a marker for impaired kidney function) and/or urine exam by a physician. Similarly, having a low score does not guarantee you are free of this ...

New clinical data shows chromium picolinate improves cognitive function

... of the brain associated with working memory. The subjects receiving placebo showed no such change. At the completion of the study, chromium to creatinine ratios were significantly elevated in the chromium picolinate group (p = .008) indicating increased levels of chromium in the blood. The groups did ...
Creatinine in Biological Technology

Nile Therapeutics Announces Positive Results from Phase 1b Safety and Pharmacodynamics Study of CD-NP in Patients with Heart Failure

... was assessed via biomarkers including serum creatinine and creatinine clearance, the most frequently used surrogate ... a 24-hour infusion of CD-NP at 3 ng/kg/min, serum creatinine was reduced by 10% (p=0.03). Infusions of 10 and ...

Astellas Receives FDA Approval for Use of Prograf(R) (Tacrolimus) in Conjunction With Mycophenolate Mofetil (MMF) in Kidney Transplant Recipients

... (3.0%). Patients in the Prograf group exhibited higher estimated creatinine clearance rates (eCLcr) using the Cockcroft-Gault formula and experienced ... (20.4%), CyA/MMF (36.2% and 31.6%) and Siro/MMF (46.4%). Median creatinine clearance rate, a measure of kidney function (eCLcr) at 12 months was ...

Kidneys for Transplant Function Earlier and Last Longer When Preserved in a Machine Compared to the Traditional Box of Ice

... stay in hospital, primary non-function of the transplanted kidney, serum creatinine and clearance after transplantation, acute rejection and calcineurin ... the first year post-transplant (hazard ratio 0.52; P=0.03). Serum creatinine values were significantly lower for machine perfused kidney recipients ...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

... comparable. OGX-011 treatment was well tolerated in combination with docetaxel. There was an increase in incidence of mild fever, chills and creatinine levels (a laboratory measure for reduced kidney function) and a moderate to significant decrease in circulating lymphocytes in the blood (another ...

Nile Therapeutics Reports 2008 Fourth Quarter and Full Year Financial Results and Announces Conference Call on March 10, 2009

... increase in diuresis concurrent with furosemide; and With a 24 hour infusion, CD-NP produced statistically significant decreases in serum creatinine and cystatin-c, consistent with enhanced renal function. In the second quarter of 2009, Nile intends to initiate a 30 patient ...

Video: Experts Unite to Help People Manage Spring Nasal Allergy Sneezin'

... XYZAL(R) or to cetirizine (observed reactions range from urticaria to anaphylaxis); patients with end-stage renal impairment at less than 10 mL/min creatinine clearance or patients undergoing hemodialysis; and pediatric patients aged 6 to 11 years with impaired renal function. Patients should be ...

Rules-Based Medicine, Inc. Launches Human Kidney Damage Biomarker Panel

... with new safety initiatives. Historically, regulatory agencies have required drug companies to provide results of blood urea nitrogen (BUN) and serum creatinine tests as indicators of kidney damage. Studies, however, suggest these tests detect only late signs of kidney damage and provide no information on the ...

FDA Approves Boston Scientific's Express(R) SD Renal Stent System

... a statistically significant improvement in systolic blood pressure and no statistical difference in either diastolic blood pressure or serum creatinine levels from baseline through three years(1). Nine-month results demonstrated a binary restenosis rate of 21.3 percent (23/108), low target lesion ...

Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure

... -- Trend toward reduction in right atrial pressure -- Trend toward increase in cardiac output -- No hypotension -- No change in serum creatinine About the Study The objective of the Phase 2a study is to assess hemodynamic and renal effects of CD-NP in patients with acute heart failure. In ...

Acrongenomics on Track to Acquire Molecular Vision

... fully portable unit complete with an LCD display. Before the end of Q1 2008 the PoC technology will be a robust standalone unit capable of measuring creatinine and vitamin C simultaneously in urine with the same level of accuracy and sensitivity to a pathology laboratory test using a multi-channel device in ...
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