... of study have led to the knowledge that hemoglobin uses mechanisms of cooperativity
to optimize its function; that is to say, to collect the greatest amount ... possible in the lungs and release it in tissues. These mechanisms of cooperativity
are related to changes in the structure of the hemoglobin protein. ...
Immune cell communication key to hunting viruses, Jefferson immunologists show
... able to see something no one had seen before ?a very strong contribution of non-viral peptide-MHC interaction with a co-receptor," he says. "Such cooperativity
we think can be achieved when MHC complexes are close to each other.
"We've shown that when we try to mimic the positioning of MHC protein on ...
is a phenomenon in biology displayed by enzymes or receptors that have multiple binding sites .
When substrate bonds to the active site ...
... OR1, OR2, and OR3, in the order OR1 > OR2 > OR3.
Binding of a cI dimer to OR1 enhances binding of a second cI dimer to OR2, an effect called cooperativity
. Thus, OR1 and OR2 are almost always simultaneously occupied by cI. However, this does not increase the affinity between cI and OR3, which will ...
... Annu Rev Neurosci. 2000;23:649-711. PMID 10845078
McNaughton BL, Douglas RM, Goddard GV. "Synaptic enhancement in fascia dentata: cooperativity
among coactive afferents." Brain Res. 1978 Nov 24;157(2):277-93. PMID 719524
Murphy GG, Glanzman DL. "Enhancement of sensorimotor ...
... nucleosomes and microtubules . Changes in quaternary structure are called conformational changes . It is through such changes, which underlie cooperativity
and allostery in "multimeric" enzymes, that many proteins undergo regulation and perform their physiological function.
The above definition ...
... structure , secondary structure , tertiary structure , quaternary structure , structural domain , structural motif , protein subunit , cooperativity
, chaperonin , structural genomics , Important publications in structural biology
Nature: Structural & ...
is a phenomenon in biology displayed by ... referred to as cooperative binding. We also see cooperativity
in large chain molecules made of many identical ... is referred to as ... 2 Mechanisms of cooperativity
. 3 Additional information. 4 See also. 5 ... ...
... between the CT-L and the PGPH ... 3.2 Methods that measure the size of the intact complex directly ... through such changes, which underlie cooperativity
and allostery in "multimeric" ... Dynamics of Biomedical Molecules in Vision, Allostery , and Folding ... Allostery down regulates the ...