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Contractile in Medical News

From mother to daughters: A central mystery in cell division solved

... Their work describing the mechanism of the contractile ring a structure that pinches the mother cell ... of one cell into two is accomplished by the contractile ring, which is assembled from two protein ... The spindle then directs the assembly of a contractile ring, which forms a belt around the cell middle. ...

JCI online early table of contents: Jan. 10 2008

... genes, which make proteins that manifest the contractile phenotype of SMCs. As elimination of myocardin in ... expression of proteins responsible for the SMC contractile phenotype, the authors suggested that myocardin has a central role in maintaining the SMC contractile phenotype and that this probably explains, in ...

Chemical can reproduce complications for some patients

... cardiac output, heart rate, stroke volume, blood pressure, and heart contractile function. Measurements were made at baseline and again 60 minutes after ... the CHX rats. Stroke volume, in turn, was depressed because the inherent contractile ability of the heart was significantly reduced. CHX exposure also ...

UC Davis researchers find evidence of mature heart cell potential in embryonic stem cells

... move on and engineer the calcium-handling properties in order to enhance contractile properties in cardiomyocytes for both improved safety and functional ... study is a first step toward deriving cardiomyocytes with fully functional contractile properties from human embryonic stem cells. With heart transplants being ...

Stem cells derived from adult testes produce wide range of tissue types

... stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue. The research offers a promising new source of stem cells ... vivo into working blood vessel (endothelial) cells and tissue, as well as contractile cardiac tissue, brain cells, and a host of other cell types. They also ...

Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers

... the management of heart failure. It targets the redox-nitiric oxide imbalance, which is increasingly recognized as a major factor in poor myocardial contractile efficiency, the hallmark manifestation of this disorder. About Heart Failure Heart failure, a condition characterized by the inability of ...

Cardium Reports on Recent Highlights, Financial Results and 2009 Outlook

... angiogenesis within the heart and that the zone of heart attack related tissue damage (the infarct zone) was significantly reduced, and cardiac contractile function significantly improved - further highlighting the potential value of these therapeutic approaches. Financial Report For the ...

UNT Health Science Center Researchers Discover Eating Less May Not Increase Life Expectancy

... Miller School of Medicine, University of Miami , and the Institute of Physics at the Marie Curie-Sklodowska University to study activity in cardiac contractile fibrils of skeletal muscle using fluorescence. They found the lifetime of a fluorescent marker was high in the presence of actin, a component of ...

Saving teeth by using periodontal ligament regeneration

... could be generated in this way. The composition of the collagen network in which the cells are located has a considerable influence on the contractile properties of the cells. Contraction of the cells creates internal tension in the network which keeps the cells active. The network must be well ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology Meeting

... resulting in blindness in that region. When scars occur on the vitreal surface, termed proliferative vitreoretinopathy (PVR), the cells become contractile and cause re-detachment of the retina, again resulting in blindness. We show here using an animal model of retinal detachment that a single ...

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Contractile in Medical Technology

FAU Receives Patent for Invention Which Induces and Restores Cardiac Muscle Function

... that affect heart cell differentiation and regulation of the synthesis of contractile proteins within cardiac muscle cells that allows cells to contract. ... rescuing mutant hearts by promoting the development and differentiation of contractile cardiac muscle cells from non-contractile, pre-cardiac, non-muscle cells. ...

Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy

... muscle, and they are the only progenitor cell in the human body that normally develop the ability to contract making them more likely to restore contractile function of the damaged heart. About Bioheart, Inc. Bioheart, Inc. is committed to delivering intelligent devices and biologics that help ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

... the recovery of photoreceptor cells even though the retina is reattached. When such cells grow on the vitreal surface of the retina, they can form contractile scar tissue leading to re-detachment of the retina. Together, these conditions are termed proliferative vitreoretinopathy (PVR). PVR remains the most ...

Research Documents Scalable Production, Survival Following Engraftment and Positive Impact on Cardiac Function in Infarcted Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for Heart Failure

... using non-conditioned, serum-free media and a directed differentiation protocol that produces cells with the phenotypic, electrophysiological and contractile properties of human immature cardiomyocytes. The new protocol produces cardiomyocytes with high efficiency, yielding 10-100 fold more cardiomyocytes ...
Contractile in Medical Dictionary

Lactic acid

... The accumulation of lactic acid in muscle tissue and the depletion of glycogen (stored glucose ) results in muscle fatigue . The contractile properties of muscle are reduced, and continued exertion is impossible unless the muscle is allowed to rest. One systemic measure of tissue ...

Ungual

... the end of the nail (nail bed) and in the nail. peritrichous; peritrichous flagellation; peritrochanteric; peritrochium; peritropal; peritubular contractile cells; peritubular dentin; peritubular zone; perityphlic; perityphlitis; perityphlitis actinomycotica; periumbilical; peri ungual ; ... Warts ...
Contractile in Biological News

Study may aid efforts to prevent uncontrolled cell division in cancer

... have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate ... though both cell volume and the length of the contractile ring are reduced during successive rounds of ...

New mechanical insights into wound healing and scar tissue formation

... migrating and, like Popeye, change into powerful contractile cells, anchoring themselves to the matrix and ... is crucial for this switch from migrating to contractile cells. To make this change, the fibroblasts need ... factor is available, the fibroblast expresses the contractile proteins, sticks more firmly to the matrix and ...

How molecular muscles help cells divide

... and then observe the way a cell assembles the contractile ring, the short-lived force-producing structure ... between the two daughter cell nuclei. This contractile ring is thought to operate like an old-fashioned ... Since the 1970s, it has been known that the contractile ring is made up of muscle-like actin and myosin ...

'Smart' flower bulbs pull themselves to deeper ground

... growth is very rare in plants, and the sort of contractile proteins that are so well known to drive ... on the "Nelly White" variety of Easter lily. contractile roots were found to respond to light signals ... to certain types of blue light forced new contractile roots to be formed on the bulbs and helped ...

Studies point to novel target for treating arrhythmias

... the role of calcium inside heart muscle cells. Calcium is central to the contractile cycle. After it is released from its storage sites in heart muscle cells, it interacts with proteins called troponins, part of the cell's myofilament contractile apparatus. The interaction of calcium with troponins regulates myofilament ...

Study: Fountain of youth for your heart?

... has shown that a protein that is responsible for transporting fat into the contractile cells of the heart actually increases. Based on this finding, Dyck ... suggest that the protein responsible for transporting fat into the contractile cells of the heart may be a candidate for drug inhibition and that this ...

Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction

... and MRI evidence of significant improvement in cardiac structure and contractile function. Gerons scientists conducted the study in collaboration with ... vessel formation, possibly contributing to both cell survival and improved contractile function. The scalable production system allows for production runs at ...

Heart attacks: The tipping point

... last year in the Biophysical Journal . Keeping His Eye on the Balance "Seventy percent of the heart is made up of myocytes, which are contractile muscle cells. The remaining 30% is mostly rigid structural cells called fibroblasts that work to hold the muscle in place," Dr. Zlochiver explains. ...

Caltech scientists show function of helical band in heart

... for the surgical treatment of heart disease, Gharib says. "It's going to change the way we repair the heart," he explains. Knowing that the contractile wave travels along the helical pathway--instead of occurring throughout the heart all at once--has implications for which parts of the heart will be ...

Dense tissue promotes aggressive cancers

... team examined how cells convert a sense of matrix rigidity into intracellular signals, a process called mechanotransduction. Proteins that generate contractile forces, such as myosin "motors," are important players in mechanotransduction. Weaver and colleagues confirmed that myosin motors are involved in ...

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Contractile in Biological Technology

United States FDA Clears the REGEN Trial to Test Bioheart's Combination Gene and Stem Cell Therapy in Heart Failure Patients

... from heart failure, the cells are injected into the scar tissue that has formed in the patient's heart. The goal of MyoCell SDF-1 is to grow new contractile muscle within the scar tissue that will have the ability to release additional beneficial proteins to assist in the tissue repair process and improve ...

Cordex Pharma Forms Heart Failure Medical Advisory Board

... the management of heart failure. It targets the redox-nitiric oxide imbalance, which is increasingly recognized as a major factor in poor myocardial contractile efficiency, the hallmark manifestation of this disorder. The Medical Advisory Board is chaired by Joshua M. Hare, M.D., the Louis Lemberg ...
Contractile in Biological Definition

Actin

... helix . Bundles There are two types of actin bundles: parallel and contractile bundles. In parallel bundles, the filaments are spaced 14 nm apart by the ... actin filament in a relaxing or contracting movement by usage of ADP. In contractile bundles, the actin-bundling protein actinin separates each filament by 40 ...

Actin

... helix . Bundles There are two types of actin bundles: parallel and contractile bundles. In parallel bundles, the filaments are spaced 14 nm apart by the ... actin filament in a relaxing or contracting movement by usage of ADP. In contractile bundles, the actin-bundling protein actinin separates each filament by 40 ...

Vacuole

... particles, or even other cells, by the cell for digestion . A contractile vacuole is used to pump excess water out of the cell to reduce osmotic pressure and keep the cell from bursting. contractile vacuoles are found in some freshwater protozoa . Vacuoles in plant ...

Biological tissue

... name suggests, connective tissue holds everything together. Blood is considered a connective tissue. Muscle tissue - Muscle cells contain contractile filaments that move past each other and change the size of the cell. Nervous tissue - cells forming the brain , spinal cord and peripheral ...

Eukaryote

... that break down the contents of food vacuoles, and peroxisomes are used to break down peroxide which is toxic otherwise. Many protozoa have contractile vacuoles, which collect and expel excess water, and extrusomes , which expel material used to deflect predators or capture prey. In multicellular ...

Muscle

... Muscle is a contractile form of tissue . It is one of the four major tissue types, the other three being epithelium , connective tissue and nervous tissue . Muscle ...

Myosin

... The Muscle is composed of single muscle cells (sometimes known as "muscle fibers"). Within the cells are myofibrils ; the basic unit of a the contractile apparatus of a myofibril is the sarcomere , which is composed of three different filament systems, the thin filaments assembled by actin ...

Osmoregulation

... sand-dune marran grass has rolled leaves with stomata on the inner surface. Osmoregulation in protoctists and animals Amoeba makes us of a contractile vacuole to collect excretory waste, such as ammonia , from the intracellular fluid by both diffusion and active transport. As osmotic action pushes ...

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Contractile in Biological Dictionary

Vacuole

... and containing water, food, or metabolic waste contractile vacuole n. A membrane-bound organelle found ... harmony seen in the natural ... Basically, the contractile vacuole stores extra water. ... Vacuole ... ... information on Vacuole ... They also use contractile vacuole s to pump out excess water so ... This ...

Myosin

... muscle cells, responsible for the elastic and contractile properties of muscle ... Each myosin ... ... Only myosin -IC concentrates around contractile vacuoles and ... The Cell - A Molecular ... ... Myosin and the protein actin form the contractile units (sarcomeres) of skeletal ... External ...

Muscle contraction

... implies shortening, ... Muscle is the contractile tissue of the body and is derived from the ... of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change ... . Bartter Syndrome - tetany ... ... are the contractile units of the muscle and are organized into ...

Muscle

... Muscle is the contractile tissue of the body and is derived from the ... of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change ... Much of muscle contraction ... Muscle is the contractile tissue of the body and is derived from the ...

Contractile vacuole

... A contractile vacuole is a sub-cellular structure ... are found in both plant and animal cells. contractile vacuole n. A membrane-bound organelle found ... manner from within the cell to the outside contractile vacuole This article does not cite any ... How ...

Skeletal muscle

... Muscle is the contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They ...

Involuntary muscle

... by spinal nerve centres, with no direct ... Muscle is the contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They ...

Cardiac muscle

... muscle is one of three major types of muscle ... Muscle is the contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They ...

Vacuoles

... with 7 pages of encyclopedia entries, essays, summaries, research information, and more. ... Vacuoles are organelles of plant, fungal, and ... contractile vacuole n. A membrane-bound organelle found in certain protists that pumps fluid in a cyclical manner from within the cell to the outside ...

Transport vesicle

... the ... The European Bioinformatics Institute ... vesicle -mediated transport ... GO:0048489 synaptic vesicle transport . I. GO:0070177 contractile vacuole discharge ... Transport vesicles . Definition(s) Vesicles that are involved in shuttling cargo from the ... Definition from: Unified ...

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