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Conjugation in Medical News

SAFC Pharma's St. Louis HPAPI Conjugates Facility Receives SafeBridge Certification

... potent active pharmaceutical ingredient (HPAPI) conjugation suite, by SafeBridge (R) Consultants, Inc. for ... commissioned in September 2008, enables the conjugation of Highly Potent Active Pharmaceutical ... SafeBridge certification status for our HPAPI conjugation suite provides our customers with complete ...

Nektar Announces UCB's Cimzia(R) Approved by U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis

... developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise ... or commercial success with any other PEGylated or advanced polymer conjugation products, and (3) other important risks and uncertainties set forth in the ...

SAFC Pharma Commissions HPAPI Conjugates Facility at St. Louis

... to support oncology drug development. The 600-sq ft suite will enable the conjugation of HPAPIs to a variety of targeted delivery molecules, including ... most potent) while the St. Louis site has more than 30 years experience in conjugation technology. "The HPAPI market has grown at a high double-digit pace; the ...

Nektar Therapeutics to Present at the Deutsche Bank 34th Annual Health Care Conference in Boston

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

Nektar to Announce Financial Results for the First Quarter of 2009 on Wednesday, May 6, 2009, After Close of U.S.-Based Financial Markets

... call. About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

NKTR-105 Demonstrates Superior Antitumor Activity and Improved Pharmacokinetics Over Docetaxel in Preclinical Studies Presented at AACR

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...
Conjugation in Medical Technology

Nektar Therapeutics Reports Second Quarter 2009 Financial Results

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

Nektar Announces Positive Results from Phase 2 Study of Oral NKTR-118 in Patients with Opioid-Induced Constipation (OIC)

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

Ambrx Enters FGF-21 Type 2 Diabetes Drug Discovery Collaboration with Merck and Co. Inc.

... of use. Ambrx's core ReCODE(TM) technology enables the precise, site-specific substitution of a novel amino acid within a protein. This allows the conjugation of proteins with additional molecules that can serve to modulate their pharmacokinetic profile or biological function. Ambrx's ReCODE(TM) technology ...

Intercell AG: Novel tuberculosis Vaccine Shows Promising Immunogenicity and Safety Profile

... anti-microbial peptide, KLK, and an immunostimulatory oligodeoxynucleotide, ODN1a. The two component solution can be simply mixed with antigens, no conjugation is required. About Statens Serum Institut (SSI): Statens Serum Institut ( www.ssi.dk ) is a ...

Poster on Cyclosert Drug Delivery Presented at AACR Meeting

... essential for efficient delivery of drugs through the bloodstream. Tubulysin A is already better than many comparable agents in this respect, but in conjugation with Cyclosert, solubility improves dramatically." In trials on animals, the tubulysin-Cyclosert conjugate was well tolerated, in contrast to ...
Conjugation in Medical Products

Custom Conjugation

Description:... Custom conjugation ...
Company:BioAssay Works, L.L.C.

Coat-Block-Run Conjugation Kit pH 8-11

Description:... Gold Labeling kit for antibodies, the Coat-Block-Run conjugation Kit pH 8-11; contains 1 bottle each of 20 nm and 40 nm Naked ...
Company:BioAssay Works, L.L.C.

Iso-Electric Determination Kit

Description:... Iso-Electric Determination Kit; contains 1 bottle of 40 nm Naked Gold Iso-Electric Determination Kit to optimize gold conjugation of ...
Company:BioAssay Works, L.L.C.

Coat-Block-Run Conjugation Kit pH 5-8

Description:... Gold Labeling kit for antibodies, the Coat-Block-Run conjugation Kit pH 5-8; contains 1 bottle each of 20 nm and 40 nm Naked ...
Company:BioAssay Works, L.L.C.

Unconjugated Estriol, Ultra-Sensitive EIA Test

Description:... late-gestational peak which is ~2-3 orders of magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact ...
Company:Diagnostic Systems Laboratories, Inc.

Unconjugated Estriol, Ultra-Sensitive RIA Test

Description:... late-gestational peak which is ~2-3 orders of magnitude greater than non-pregnant levels [1,2]. In the maternal circulation, estriol undergoes rapid conjugation in the liver followed by urinary excretion with a half-life of ~20 minutes [2]. Since normal estriol production depends on an intact ...
Company:Diagnostic Systems Laboratories, Inc.
Conjugation in Medical Definition

Artificial induction of immunity

... more contemporary approach for "boosting" the immune response of simpler immunogenic molecules (known as antigens ) is to conjugate the antigens. conjugation is the attachment to the antigen of another substance which also generates an immune response, thus amplifying the overall response and causing a ...
Conjugation in Biological News

A paradigm shift in immune response regulation

... been gradually pieced together to show that modifications in the cell protein - including the addition of phosphate groups (phosphorylation) or the conjugation of small modifier ubiquitin (ubiquitination) - play a central role in controlling the immune system. Scientists at Frankfurt's Goethe University ...

Researchers develop way to calculate speed of bacterial sex

... its impact in nature, current computer models of conjugation were pretty basic," said Ginn. UC-Davis ... a previously established conceptual framework of conjugation processes in an isolated environment, researchers ... new mathematical model of bacterial transport and conjugation that focused on subsurface bacteria colonizing ...

Scientists design simple dipstick test for cocaine, other drugs

... The appropriate aptamer-linked nanoparticle aggregates are placed on the conjugation pad, streptavidin is applied as a thin line to the membrane pad, and the ... the wicking pad carries the fluid to the nanoparticle aggregates on the conjugation pad. The rehydrated aggregates then migrate to the edge of the membrane, ...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

... bacteria that could suppress over-replication of the key plasmid. This so-called "Trojan horse" could then be used to spread the killer plasmid via conjugation to targeted bacterial pathogens that lacked the ability to resist over-replication. "We harnessed this plasmid," thought Filutowicz. "Now, how ...

MSKCC researchers uncover structure of key protein complex in cells

... instead appears to alter their function in different ways, perhaps even by preventing ubiquitin tagging. Still, there are enough similarities between conjugation of SUMO and ubiquitin that the latest findings could help researchers understand both. "The structural network has revealed a mechanism that may be ...
Conjugation in Biological Technology

SoluLinK Introduces New One-Shot ChromaLink(TM) Biotin Antibody Labeling Kit with Built-in Biotin Quantification.

... needs in detection with effective and proven conjugation technology, supplied in a complete, easy-to-use ... SoluLinK is the leader in the development of conjugation reagents, easy-to-use complete kits, and conjugation services for the life science research, ...

SoluLinK Introduces NanoLink(TM) Streptavidin Magnetic Microspheres

... -- SoluLinK, Inc., a leader in next-generation conjugation products and kits, is proud to announce ... efforts in leveraging SoluLinK's next-generation conjugation technology into formats that enable ... manufacturing and marketing of advanced conjugation reagents (HydraLink(TM)) biotinylation ...

SoluLinK Introduces ChromaLink(TM) Biotin Labeling Kit to Biotinylate and Measure With One Reagent

... --- SoluLinK, Inc., a leader in biomolecular conjugation products and kits, announced the introduction ... SoluLinK's continuous and ongoing innovation of conjugation chemistry has provided significant contributions ... has established a strong leadership position in conjugation and continues to actively build, maintain, ...

SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite

... HPAPIs per batch. SAFC President, Frank Wicks, commented, "High potency conjugation is an exciting new technology that demands a very special combination of specific skills. Adding HPAPI conjugation capacity enables SAFC to further vertically integrate our contract ...

Nektar Therapeutics to Present at the BMO Capital Markets 9th Annual Focus on Healthcare Conference in New York City

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

Nektar to Announce Financial Results for the Second Quarter of 2009 on Tuesday, August 4, 2009, After Close of U.S.-Based Financial Markets

... About Nektar Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms. Nektar's technology and drug development expertise have enabled nine approved products for partners, which include leading ...

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Conjugation in Biological Products

Antibody Modification Services from Genescript

Description:... (up to 100 mg) $560.00 SC1061 Biotin conjugation (up to 20 mg) $275.00 SC1062 HRP conjugation (up to 20 mg) $275.00 SC1063 FITC conjugation (up to 20 mg) $275.00 ...
Company:Genescript

UBC Fractions Extract from GeneTex

Description:... represent the full compliment of purified conjugation enzymes (E1, E2s, and E3s) that are found in ... such as lysozyme and beta-lactoglobulin. These conjugation fractions contain ubiquitin c-terminal ... I. Includes complimentary fractions for 2-5 conjugation reactions depending on conditions. Type: ...
Company:GeneTex

Phospho-peptide Antibody from Proteintech Group, Inc.

Description:... MS-spec check purity above 90%, 20 mg will be returned to customer conjugation of peptide to KLH protein Rabbits x 2, Maintenance 102 ... ELISA x1/each Purification of antiserum over antigen (30 ml) conjugation of antigen peptide to Sepharose, 3 ml column Written report of antibody ...
Company:Proteintech Group, Inc.

SureLINK Bioconjugation Kit from KPL

Description:... linkers SFB and SANH along with reagents for quantifying conjugation efficiencies. It enables conjugation of various tags including enzymes, fluorophores, biotin and other tags ...
Company:KPL

ProteoPrep 20 Plasma Immunodepletion Kit from Sigma-Aldrich

Description:... or go straight to mass spectrometry. This is based on a unique conjugation process using small recombinant immunoaffinity ligands and conventional antibodies that permits high density conjugation on the support. The ligand selection ensures optimal specificity. Typical ...
Company:Sigma-Aldrich

QXL 520 C2 maleimide from AnaSpec

Description:... increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification that is often required in the conjugation processes. 5-TAMRA is more often used than 6-TAMRA for labeling peptides and proteins. 6-TAMRA is predominately used for labeling nucleotides and ...
Company:AnaSpec

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Conjugation in Biological Definition

Bacterium

... viral DNA from one cell to another via bacteriophage) and; bacterial conjugation (the transfer of DNA from one bacterial cell to another via a special protein structure called a conjugation pilus ). Bacteria, having acquired DNA from any of these events, can ...

Bacterium

... viral DNA from one cell to another via bacteriophage) and; bacterial conjugation (the transfer of DNA from one bacterial cell to another via a special protein structure called a conjugation pilus ). Bacteria, having acquired DNA from any of these events, can ...

Plasmid

... contain so-called tra-genes , which perform the complex process of conjugation , the sexual transfer of plasmids to another bacterium (Fig. 4). ... Fertility-(F)plasmids , which contain tra-genes. They are capable of conjugation . Resistance-(R)plasmids , which contain genes that can build a ...

Reproduction

... this domestic labor has historically been the responsibility of women; thus it is of particular interest in feminist economics. See also conjugation sexual intercourse father paternity mother custody self-replication reproductive technology fertility issues ...

Bacterial conjugation

... Bacterial conjugation is the often regarded as the bacterial equivalent of sexual reproduction or mating ; however it is not actually sexual as it does not involve ...

Hfr cell

... F ) integrated into its genomic DNA. Hfr is the abbreviation for high frequency recombination . Unlike a normal F+ cell, hfr strains will, upon conjugation with a F- cell, attempt to transfer their entire DNA through the pilus to the F- cell. As fragile a structure as a pilus will, however, likely ...

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Conjugation in Biological Dictionary

Conjugation

... Bacterial conjugation is the transfer of genetic material between ... in 1946 by Joshua Lederberg and Edward Tatum, conjugation is a mechanism of horizontal ... inner automorphism, a type of conjugation homomorphism. conjugacy class, the image of an ...

Conjugation tube

... ... Watch this video in a new window. Bacterial conjugation . Hello, you either have JavaScript turned off or ... conjugation , tube ,biological ,biology dictionary,biology ... terms,biology abbreviations ... A conjugation tube ; a hollow hair-like appendage of ... ...

Bacterial conjugation

... Bacterial conjugation is the transfer of genetic material between ... in 1946 by Joshua Lederberg and Edward Tatum, conjugation is ... Bacterial conjugation Bacterial ...

Streptavidin

... protein purified from the bacterium ... This Cell Signaling Technology product is useful for the detection of biotinylated proteins (1,2). conjugation of horseradish peroxidase (HRP) to streptavidin is ... A 52.8 kDa non-glycosylated protein with a very high affinity for biotin. ... unit is ...

Micronucleus

... A micronucleus is the smaller nucleus in ciliate protozoans, such as the paramecium. In fission it divides by mitosis, and in conjugation furnishes the pairing of gamete nuclei, by whose reciprocal fusion a zygote nucleus is formed, which gives rise to the macronuclei and ...

Mating type

... The mating type alleles of T. thermophila are unusual in that they ... Mating type is determined during macronuclear development at conjugation by a ... Information about Mating type in the free online English ... type (redirected from Mating type ) Also found in: Medical, ...

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