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Concentration in Medical News

Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report

... Pyrazinamide in the lab, they found that the concentration of the drug declined at a rate that matches the ... "Using this model, we can actually copy this concentration profile of the drugs to human-like exposures." ... dose that depends not just on the kinetics or the concentration time profile of patients, but also how the bug ...

ZyGEM Releases Data Confirming Its prepGEM(R) Bacteria Kit Is a Simple, Universal Method for Extracting DNA from Different Bacteria Species

... these samples without first having to conduct a concentration step, thereby significantly simplifying and ... GEM(R) Bacteria kits, without the need for the concentration step that is often required before extracting DNA ... possibility of sample contamination during the concentration process. The prep GEM(R) Bacteria kit is ...

Brigham and Women's Hospital Researchers Demonstrate a More Direct Delivery of Cancer Drugs to Tumors

... inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of ... inhibit a signaling pathway and deliver a higher concentration of medication to the specific area. Details of ... drugs must be administered in high concentration throughout the body in order to destroy tumor ...

Male Hormone Treatment Provider Announces Family Doctor Alert

... depression, erectile dysfunction, fatigue, poor concentration or hot flashes, then you need to read this alert. ... Inability to maintain or build muscle Poor concentration and memory Muscle and joint aches Mood ... depression, erectile dysfunction, fatigue, poor concentration or mood swings, it is highly advised they have ...

Patent pending for pain-free method of monitoring drug levels in transplant patients

... researching the use of saliva for monitoring the concentration of two other immunosuppressive drugs, tacrolimus and sirolimus. "Routine concentration measurement for these agents is essential for ... patients is required for two reasons; if the concentration of an immunosuppressive agent is low, the patient ...

Healing heart attack victims, one cell at a time

... muscle cells) in humans. Carbon 14 atmospheric concentration levels remained relatively stable until the Cold ... cell has gone through its last cell division, the concentration of carbon 14 in DNA serves as a date mark for ... the time at which the sample's carbon 14 concentration corresponded to the atmospheric concentration. ...

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Concentration in Medical Technology

Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing

... edoxaban is most closely correlated with minimum concentration levels of the drug in the blood, and that these ... events, rather than total exposure or maximum concentration levels. These findings were presented ... or 60 mg edoxaban given either QD or BID and the concentration of edoxaban in their blood. The analysis examined ...

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

... alter the median time it took for maximum plasma concentration of d -amphetamine to be reached in the subjects ... Other pharmacokinetic parameters (maximum plasma concentration and area under curve) of active medication were ... the median time to maximum plasma amphetamine concentration was five hours. The median time to maximum ...

New Keppra XR(TM) Data Highlight Its Role for Patients with Partial-Onset Seizures

... -- The median time to peak plasma concentration was approximately 4 to 5 hours for each dose. ... total amount of drug needed to achieve the same concentration as that found in the blood). -- When the 2 x ... XR dose was taken with food, the time to peak concentration was increased by 2 hours relative to fasted ...

Orexigen(R) Therapeutics Presents Data on Its Proprietary Formulation of Naltrexone Sustained Release (SR) Used in Contrave(R)

... into the bloodstream (Tmax) and reducing the peak concentration it achieves in the blood (Cmax). A series of ... to the IR formulation. The Tmax or time to peak concentration was approximately 36 minutes slower for ... objectives by providing a lower peak plasma concentration (Cmax) than the legacy IR formulation ...

Bioheart Announces 35 Leading U.S. Heart Failure Centers Engaged in Phase II/III Marvel Trial of Myogenic Cells for Treating Advanced Heart Failure

... any unforeseen changes. This study has a cell concentration of up to 200 million cells/ml and administers 16 ... studies involving MyoCell(R) Therapy had a cell concentration of 50 million cells/ml and administered 32 ... survival and engraftment with the higher concentration of cells and lower number of injections, in part ...

Halozyme Therapeutics Announces Phase I Clinical Trial Results Demonstrating that the Combination of Recombinant Human Hyaluronidase (rHuPH20) With Humulin R(R) and with Humalog(R) Yields Faster, More Physiologic Insulin Kinetics and Better Predictability

... GD: -- The median time to maximal insulin concentration (Tmax) decreased significantly: 54% for ... 64% for Humulin R (p = 0.0002). -- Insulin concentration increased rapidly and substantially. At 3 ... for Humulin R (p -- The mean maximal insulin concentration (Cmax) was substantially increased: 90% for ...

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Concentration in Medical Products

IGFBP-3 IRMA Test

Description:... IGFBP-3, along with ALS, to regulate the actions of the IGFs. The molar concentration of IGFBP-3 in normal serum is proportional to the molar concentration of total IGFs (i.e. IGF-I + IGF-II) [1]. In addition, total IGF levels ...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-3 ELISA Test

Description:... IGFBP-3, along with ALS, to regulate the actions of the IGFs. The molar concentration of IGFBP-3 in normal serum is proportional to the molar concentration of total IGFs (i.e. IGF-I + IGF-II) [1]. In addition, total IGF levels ...
Company:Diagnostic Systems Laboratories, Inc.

Prostate Specific Antigen (PSA) - Rapid Test

Description:... prostate within the epithelial cells of the acini and ducts. Normal PSA concentration in whole blood or serum is 0.1-2.6 ng/mL. Reports have suggested that ... in diagnosis of prostate cancers. InstaTest PSA is designed to detect PSA concentration in whole blood or serum as low as 4 ng/ml within 15 minutes.There is one ...
Company:Bio-Quant, Inc.

Gentamicin Sulfate: Liquid

Description:... by binding to the 30S subunit of ribosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to viruses and mammalian cells, thereby ... than other antibiotics. The sterile solution is prepared in water at a concentration of 50 mg/mL and a stock solution prepared from the powder should be ...
Company:CellGro by Mediatech

TurboVap 500 Concentration Workstation

Description:... The TurboVap concentration Workstations from Caliper provide an automated alternative to ... and Nitrogen Blow-Down Evaporators. For over ten years TurboVap concentration technology has received enormous acclaim with over 4,000 units in use ...
Company:Caliper Life Sciences

TurboVap II Concentration Workstation

Description:... The TurboVap concentration Workstations from Caliper provide an automated alternative to ... and Nitrogen Blow-Down Evaporators. For over ten years TurboVap concentration technology has received enormous acclaim with over 4,000 units in use ...
Company:Caliper Life Sciences

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Concentration in Medical Definition

Cryostasis (clathrate hydrates)

... ionic strength and interfering with the organization of the proteins and other organized intercellular structures. Eventually, the solute concentration inside the cells reaches the eutectic and freezes. The final state of frozen tissues is pure ice in the former extracellular spaces, and inside the ...

Dose concentration

... Dose concentration is the measure of the ratio of the mass of the drug to the volume that contains it, often measured in units of moles /m 3 . ...

Medicine

... over the last century, and they have been entrusted with control of access to prescription medicines as a public health measure. This represents a concentration of power and carries both advantages and disadvantages to particular kinds of patients with particular kinds of conditions. A further twist has ...

Nuclear medicine

... bone via the hydroxyapatite for imaging. Any increased physiological function, such as due to a fracture in the bone, will usually mean increased concentration of the tracer. This often results in the appearance of a 'hot-spot' which is a focal increase in radio-accumulation, or a general increase in ...
Concentration in Medical Dictionary

Osmolality

... Osmolality measures the concentration of particles in solution. Osmolality increases ... (antidiuretic hormone ). osmolality The concentration of particles dissolved in a fluid. The ... in the blood ). A physician evaluates the concentration of urine by measuring how many particles are in ...

ACTH

... ectopic; ectopic ACTH ... CUSHING'S SYNDROME - An increased concentration of glucocorticoid hormone ( ACTH ) in the blood stream that is being ... secretion is regulated principally by plasma volume, serum potassium concentration and angiotensin II and to a lesser extent by anterior pituitary ACTH . ...

Anemia

... Anemia Related Category: Pathology (n´m), condition in which the concentration of hemoglobin in the circulating blood is below normal. Anemia is ... when there are fewer red blood cells than normal, or there is a low concentration of hemoglobin in the blood . Anemia hemoltica autoinmune idioptica ...

Erythropoietin

... cells in the kidney s. These cells are sensitive to the oxygen concentration in the blood , and increase the release of EPO when the oxygen concentration is low. EPO ( erythropoietin ): A hormone produced by the kidney ...

Irritability

... mood swings and depression Aggression Fatigue Breast tenderness Poor concentration Tearfulness The feeling of being misunderstood ... Symptoms of their ... Irritability or inappropriate outbursts of anger Difficulty with concentration Being hyper-vigilant: always being watchful and on guard and unable to ...

Parathyroid glands

... parietal pericardium ... Abnormally low extracellular calcium ion concentration can result from failure of the parathyroid glands to release parathyroid hormone , the substance responsible for the regulation of calcium concentration in the body; a deficiency in vitamin D , ... The risk of pseudogout ...

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Concentration in Biological News

Study explains potential failure of oral contraceptives with obese women

... five days for the drugs to achieve their maximum concentration in women of normal weight, an average of 10 days ... But the delay in reaching a steady state drug concentration raises questions about how well oral ... long it would take for her to reach an effective concentration level of a particular contraceptive, and this ...

Why the thumb of the right hand is on the left hand side

... release is available in German . It is the concentration of a few signaling molecules that determines the ... mechanisms accounts for the interpretation of the concentration of the signaling molecule Hedgehog. The ... Biology of the University of Innsbruck. "The concentration of Hedgehog makes the thumb of the right hand ...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

... leaves but traffic from this source to form a concentration gradient across each leaf. This graded ... a defined location, their movement establishes a concentration gradient that patterns a developing tissue such ... in plant leaves, ta-siRNAs similarly generate a concentration gradient that divides the developing leaf into a ...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

... leaves but traffic from this source to form a concentration gradient across each leaf. This graded ... a defined location, their movement establishes a concentration gradient that patterns a developing tissue such ... in plant leaves, ta-siRNAs similarly generate a concentration gradient that divides the developing leaf into a ...

Plant soybean early to increase yield

... (late-May and early-June) soybean. Oil concentration was higher at early plantings and protein concentration was higher at late planting dates. As the ... during R6 soybean growth stage (full seed) oil concentration increased and ...

How chromosomes meet in the dark -- Switch that turns on X chromosome matchmaking

... in the system reached a critical threshold - a concentration of around 0.1 mg per millilitre or less. Below ... X inactivation. However once the threshold concentration is reached it produces a tipping point or thermodynamic switch. That particular concentration of CTCF was suddenly enough to ensure that the ...

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Concentration in Biological Technology

Halozyme Therapeutics Begins Phase 2 Clinical Trial of Insulin With rHuPH20 in Type 1 Diabetic Patients

... be the area under the curve for plasma insulin concentration from zero to 60 minutes after ... additional PK data, as well as blood glucose concentration at various time points. Safety data such as ... insulin absorption and a shorter time to peak concentration when compared to Humalog alone. Results ( ...

Highest Replikin Concentrations and Cyclical Behavior Related to Human Mortality Are Found in Malaria Trypanosomes

... between 1986 and 2007. The quantitative replikin concentration (Replikin Count(TM) = number of replikins per 100 ... mortality. Cyclic increases in replikin concentration in the genome can be a mechanism of expansion of ... into a territory. In other examples, the replikin concentration of West Nile Virus was earlier found to increase ...

ANX-530 Demonstrates Equivalent Pharmacokinetics to Navelbine(R) in a Registrational Bioequivalence Clinical Study

... in the body over time. Cmax is the maximum concentration of the drug measured in the blood at any given ... 80-125% Cmax: Maximum plasma concentration AUClast: Area under the plasma concentration time curve from time zero to the last ...

Baxter to Launch GARDian(TM), a Groundbreaking Initiative That Helps Provide Continued Access to GAMMAGARD for Current Patients

... should be administered at the minimum concentration available and the minimum rate of infusion ... should be administered at the minimum concentration available and the minimum rate of infusion ... should be administered at the minimum concentration available and the minimum rate of infusion ...

Five Questions About Protopic (tacrolimus) Ointment

... Protopic is available in two concentrations: 0.1% and 0.03%. Either concentration can be used in adults, while only the 0.03% concentration is indicated for children between the ages of 2 and 15. Protopic should ...

Tobira Therapeutics Inc. Announces Phase I Data Demonstrating Pharmacokinetic Properties of TAK-652 for the Treatment of HIV

... relatively good oral bioavailability (as shown by the plasma TBR-652 concentration data) and has a long plasma half-life of TBR-652 (approximate mean of 35 ... TBR-652 plasma concentrations were well above the predicted target plasma concentration (2ng/mL) with or without food. In both studies TBR-652 was safe and well ...

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Concentration in Biological Products

Proteocon D from Gerard Biotech

Description:... This kit allows for rapid, convenient, and efficient Denatured protein concentration following PAGE. The simple bind/wash/elute process utilizes a spin column to make handling easy. The kit uses beads for concentration of proteins which were electro-eluted in their Denatured condition. The ...
Company:Gerard Biotech

Pokeweed Mitogen Spleen Cell Conditioned Medium, 25 mL from StemCell Technologies, Inc.

Description:... BFU-E, CFU-M, CFU-G and CFU-GEMM when added to methylcellulose at a final concentration of 2-5%, with addition of erythropoietin. Will also support growth of mouse IL-3 dependent cell lines at a final concentration of ....
Company:StemCell Technologies, Inc.

ProteoExtract Protein Precipitation Kit from Calbiochem

Description:... The ProteoExtract™ Protein Precipitation Kit is designed for concentration and clean up of proteins from aqueous samples. Proteomics sample analysis ... recovery is consistently higher then 90%. One kit is sufficient for the concentration and clean up of 200 samples of 0.2 ml volume. The procedure is scalable, ...
Company:Calbiochem

Proteocon N from Gerard Biotech

Description:... This kit allows for rapid, convenient, and efficient native protein concentration following PAGE. The simple bind/wash/elute process utilizes a spin column to make handling easy. The kit uses beads for concentration of proteins which were electro-eluted in their native condition. The beads ...
Company:Gerard Biotech

General DNA Sequencing Services from Polymorphic DNA Technologies, Inc.

Description:... please do not provide samples in TE. Plasmid DNA should be submitted at a concentration of 0.2 μg per μL. Please provide 2 μg of plasmid DNA per ... requested. For PCR products, please provide 15 μL of product at a concentration of .02 μg/μL to .05 μg/μL. Please also send a photo of ...
Company:Polymorphic DNA Technologies, Inc.

Mouse Anti-Cytohesin 2 Monoclonal Antibody, Unconjugated, Clone CYT2-21 from Novus Biologicals

Description:... dependent dilution. ICC: Use at an assay dependent dilution. WB: Use at a concentration of 5 - 10 ug/ml, this concentration is determined using a whole extract of rat brain. Predicted molecular ...
Company:Novus Biologicals

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Concentration in Biological Definition

Active transport

... molecules move against either an electrical or concentration gradient (collectively termed an electrochemical ... the transport of the other solute from a low concentration region to a high one. An example is the ... of calcium and sets the normal or resting concentration of this important second messenger . But the ...

ATPase

... Na + /K + ATPase ), which establishes the ionic concentration balance that maintains the cell potential . ... the side of the membrane where they are in low concentration to the side where they are in high concentration. ... This enzyme works when a proton moves down the concentration gradient, giving the enzyme a spinning motion. ...

Ion gradient

... An ion gradient is a concentration gradient of ions , it can be called an ... I.E by letting the ions diffuse through the high concentration side to the low concentration side through transmembrane proteins which can use ...

Diffusion

... As in simple diffusion, net transport is down a concentration gradient, and no additional energy has to be ... Ions Diffusion of ions depends on the concentration gradient, and the membrane potential. The net ... more slowly through the balloon wall. There is a concentration gradient in the balloon wall because the balloon ...

Fick's law of diffusion

... used in steady state diffusion , i.e., when the concentration within the diffusion volume does not change with ... of [length 2 time -1 ] c is the concentration in dimensions of [parts length -3 ] x is ... in non-steady state diffusion, i.e., when the concentration within the diffusion volume changes with respect ...

Hydrolysis

... a hydrolytic cleavage reaction, where the concentration of a metabolic precursor is low (on the order of ... X + Y Assuming that x is the final concentration of products, and that C is the initial concentration of A, and W = [H 2 O] = 55.5 molar, then x can ...

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Concentration in Biological Dictionary

Sarcoplasm

... an oxygen binding protein. The calcium concentration in sarcoplasma is also ... Definition of ... an end-plate potential lead to an increase in Ca2 concentration in the sarcoplasm ? ... sarcoplasm the ... an end-plate potential lead to an increase in Ca2 concentration in the sarcoplasm ? ... Sarcoplasm - ...

Pyrenoid

... The pyrenoid may serve to aid the concentration of dissolved carbon dioxide by ... Retrieved from ... ... The pyrenoid may serve to aid the concentration of ... Definition of pyrenoid from the ... ... The pyrenoid may serve to aid the concentration of dissolved carbon dioxide by ... Pyrenoid ...

Diffusion

... transport of molecules from a region of higher concentration to one of lower concentration by random molecular motion. The result of ... x 2= 2 D t ... Calculating the changes in concentration as diffusion progresses ... Diffusion of ...

Concentration gradient

... concentration gradient n. The graduated difference in concentration of a solute per unit distance through a ... pressure gradient in concentration and dilution ... ...

Cephalization

... means that there is a head, and therefore a concentration of ... Information about cephalization in ... in the front of a ... Cephalization is the concentration of sense organs ... - Lab 2 & 3. ... hermaphroditic w/complex ... Cephalization - concentration of the nervous tissue into a head; which allow ...

Active transport

... particles across a biological membrane against a concentration gradient. If the process uses chemical energy, ... of a chemical substance through a gradient of concentration or electrical potential in the direction opposite ... is the pumping of molecules. against their concentration gradient with ... three specific types of ...

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Other Contents
(Date:7/31/2014)... Adventist Health System, which is ... Florida Hospital Tampa, Florida Hospital Carrollwood, Florida Hospital ... Pinellas, Florida Hospital Wesley Chapel, Florida Hospital Zephyrhills, ... Heartland Medical Center Lake Placid and Florida Hospital ... Most Wired Hospitals and Health Systems, which is ...
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(Date:7/31/2014)... by the National Science Foundation (NSF), counters a ... atmospheric warming, indicating instead that certain Arctic lakes ... the atmosphere. , The study, published this ... on thermokarst lakes, which occur as permafrost thaws ... fresh water, converting what was previously frozen land ...
(Date:7/31/2014)... biomass burning burning forests to create agricultural ... agriculture and wildfires figures into both climate ... release of a new study by Stanford University ... the degree of that contribution had never been ... paper published July 30 in the Journal ...
(Date:7/31/2014)... the roughly 156,000 gas stations across the United ... of underground gas storage tankscorrosion that could result ... source of drinking water. In recent years, field ... corroding gas storage tank components such as sump ... of gasoline-ethanol blends and the presence of bacteria, ...
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