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Colorectal in Medical News

Cost-effectiveness of cetuximab in metastatic colorectal cancer

... more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type ... treatment for all patients with advanced colorectal cancer," the authors write. "Use of cetuximab may ... shows that even when restricted to metastatic colorectal cancer patients with wild-type KRAS tumors, the ...

Micromet, Inc. Reports Second Quarter 2009 Financial Results

... antibodies against KRAS- and BRAF-mutated human colorectal cancer cells at the AACR meeting. The ... T cells to eliminate EpCAM-expressing human colorectal cancer stem cells in cell culture and in animal ... Adecatumomab is in a phase 2 clinical trial in colorectal carcinoma patients after complete resection of ...

Genetic testing may be valuable in treating colorectal cancer

... patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a ... pharmacogenetic testing for metastatic colorectal cancer, but remains to be verified by clinical ... irinotecan) chemotherapy regimen for metastatic colorectal cancer. The model assumed that under usual care, ...

Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)

... predictive biomarker in patients with metastatic colorectal cancer (mCRC) treated with anti-EGFr antibody was ... that retrospective subset analyses of metastatic colorectal cancer trials have not shown a treatment benefit ... Vectibix is not recommended for the treatment of colorectal cancer with these mutations. The ...

News from Cancer

... August 15, 2009 RACIAL DISPARITIES IN colorectal CANCER SURVIVAL DISSIPATE AFTER ADJUSTING FOR OTHER DEMOGRAPHIC AND CLINICAL FACTORS colorectal cancer (CRC) is the third leading cause of cancer ... to care. Article: "Racial Differences in colorectal Cancer Survival in the Detroit Metropolitan ...

Two Fred Hutchinson Cancer Research Center Scientists Receive Presidential Early Career Award

... components may play in preventing prostate and colorectal cancer. Selenium, for example, found in ... consortium for genomewide association studies of colorectal cancer that combines data from several ... aims to determine whether genetic variants affect colorectal cancer and whether environmental factors, ...

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Colorectal in Medical Technology

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... of patients with KRAS wild-type metastatic colorectal cancer (mCRC). "We believe that these ... an important advance for patients with metastatic colorectal cancer," said Roger M. Perlmutter, M.D., Ph.D., ... combination with chemotherapy for M etastatic colorectal cancer to determine E fficacy) enrolled 1,183 ...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

... that, "retrospective analyses of metastatic colorectal cancer trials have not shown a treatment benefit ... the drugs is not recommended for the treatment of colorectal cancer patients with these mutations. ... technical bulletin, " KRAS Mutation Detection in colorectal Cancer; For Determining Mutational Status that ...

Access Pharmaceuticals Announces Publication of Thiarabine Combination Data

... Thiarabine Achieves High Cure Rate in a colorectal Cancer Model DALLAS, June 4 ... than achieved by either agent alone. In one colorectal cancer model, 66% of mice were cured of their ... cures were observed in several models including colorectal cancer and leukemia. The combination of agents ...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... in a poster during the Gastrointestinal Cancer -- colorectal session at the 45th Annual Meeting of the ... this program forward in patients with advanced colorectal cancer." Mr. Bentsur added, "We wish to thank ... Cancer Society, not counting skin cancers, colorectal cancer is the third most common cancer diagnosed ...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... in a poster during the Gastrointestinal Cancer - colorectal session at the 45th Annual Meeting of the ... this program forward in patients with advanced colorectal cancer." Mr. Bentsur added, "We wish to thank ... Cancer Society, not counting skin cancers, colorectal cancer is the third most common cancer diagnosed ...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

... to Oxaliplatin for First-Line Treatment of colorectal Cancer - - Poniard Management Team to Host ... 2 trial of picoplatin in patients with metastatic colorectal cancer (CRC). The new data demonstrated that ... is the current standard of care for metastatic colorectal cancer, but is associated with severe neuropathy ...

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Colorectal in Medical Products

Hemoccult SENSA Fecal Occult Blood Test

Description:... detection of hidden blood in stool specimens, an early indication of colorectal cancer. Many recent studies show that annual screening with Hemoccult will reduce mortality from colorectal cancer by 20 to 40 ....
Company:Beckman Coulter, Inc

Pocket Guide to Colorectal Cancer Drugs and Treatment

Description:... Focuses primarily on the drugs used for treatment and symptom management for colorectal ....
Company:Skyscape, Inc.

Hemoccult ICT

Description:... polyps than traditional guaiac-based FOBTs. Because of its superior specificity for lower GI bleeding, Hemoccult ICT is an ideal screening tool for colorectal cancer (CRC), and this specificity also reduces the number of false positive test results. Safe and non-invasive, Hemoccult ICT is very patient ...
Company:Beckman Coulter, Inc.

Hemoccult ICT Fecal Occult Blood Test

Description:... polyps than traditional guaiac-based FOBTs. Because of its superior specificity for lower GI bleeding, Hemoccult ICT is an ideal screening tool for colorectal cancer (CRC), and this specificity also reduces the number of false positive test results. Safe and non-invasive, Hemoccult ICT is very patient ...
Company:Beckman Coulter, Inc

VALTRAC™ Sizer Device

Description:... Device for use with VALTRAC™ Devices (Single Use Biofragmentable Anastomosis Ring). The Purstring™ Device is indicated in intestinal, colorectal and esophageal surgery for the placement of purse string sutures and is intended for use with VALTRAC™ and EEA™ ....
Company:Autosuture

VALTRAC™ Reusable Purstring Device

Description:... Device for use with VALTRAC™ Devices (Single Use Biofragmentable Anastomosis Ring). The Purstring™ Device is indicated in intestinal, colorectal and esophageal surgery for the placement of purse string sutures and is intended for use with VALTRAC™ and EEA™ ....
Company:Autosuture

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Colorectal in Medical Definition

European Prospective Investigation into Cancer and Nutrition

... analyses are focusing particularly on stomach , colorectal , breast , prostate and lung cancers. The ... of fibre, fish, milk and cheese reduce risk of colorectal cancer, while red and processed meat increase ... al . Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation ...

Full-body scan

... JA, Puckett ML, Hildebrandt HA, Wong RK, Nugent PA, Mysliwiec PA, Schindler WR. (Mar 2003). "Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults.". New England Journal of Medicine 349 (23): 2191 - 2200. PMID 14657426 . ^ Lauenstein TC, Semelka ...

Pathology

... Colon Diarrhea - Appendicitis - Diverticulitis - Diverticulosis - IBD ( Crohn's , Ulcerative colitis ) - IBS - Constipation - colorectal cancer - Hirschsprung's - Pseudomembranous colitis Hernia Inguinal - Femoral - Umbilical - Incisional - Diaphragmatic ...
Colorectal in Medical Dictionary

Adenoma

... s eventually become cancer ous and develop into colorectal cancer . One cause of Cushing's syndrome is ... gland ( adenoma ). Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme research paper ....

Blindness

... ( Color Blindness ) Color Blindness colorectal Cancer ( colorectal Cancer ) colorectal Cancer ...

Colitis

... disease have an increased risk of developing colorectal cancer . Listen as experts explain the link ... that increase a person's risk for developing colorectal cancer include a family history of the disease ... cancer include heredity (family history), colorectal polyps , and long-standing ulcerative colitis ....

Colon cancer screening

... Medicine Makes Inroads Doctor-Focused colorectal Screening Campaign Fails Lumpectomy Fine for ... Breast Cancer s Screening Combo May Improve colorectal Cancer ... Colon Cancer Screening : An Easy ... cancer , such as those with a family history of colorectal cancer . Halbert CH, Lynch H, Lynch J, et al.: ...

Colon

... family history of: The presence of a history of colorectal cancer in a family. Colon cancer ... survival and quality of life for patients with colorectal cancer that has spread to that organ , ... A colorectal polyp is an abnormal growth of tissue on the ...

Colon polyp

... wall. Screen for colon polyp s or colorectal cancer . Most medical experts recommend colon ... for colon cancer , ... Colon Polyp s ( colorectal Polyps ) Color Vision Deficiency ( Color Blindness ) Color Blindness colorectal Cancer ...

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Colorectal in Biological News

2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award

... components may play in preventing prostate and colorectal cancer. Selenium, for example, found in ... consortium for genomewide association studies of colorectal cancer that combines data from several ... aims to determine whether genetic variants affect colorectal cancer and whether environmental factors, ...

Colorectal cancer

... associated with the formation of metastases in colorectal cancer. Now, researchers of the Max Delbrck ... Beginning in glands in the bowel lining, colorectal cancer often remains undiscovered initially. ... via the blood vessels or the lymphatic system. In colorectal cancer, these cells usually settle in the liver, ...

Study finds colorectal cancer rates increasing worldwide

... ATLANTAJune 9, 2009A new study finds colorectal cancer incidence rates for both males and females ... the first in a peer-reviewed journal to present colorectal cancer incidence trends across all five ... of urbanization that affect most of the globe. colorectal cancer is the fourth most common cancer in men ...

No insurance? No colonoscopy

... John M Inadomi highlights the disparity in colorectal cancer screening (CRCS) among different ... Reports ( www.f1000medicine.com/reports ). colorectal cancer is the second leading cause of ... blood testing (FOBT) have been shown to reduce colorectal cancer incidence or mortality. Inadomi draws ...

Hormone therapy associated with reduced colorectal cancer risk

... risk of breast cancer, may decrease their risk of colorectal cancer, according to a report published in the ... progestin was associated with a reduced risk of colorectal cancer," said Jill R. Johnson, M.P.H., a doctoral ... and colleagues identified 960 new cases of colorectal cancer in this population. Any use of estrogen ...

Scientists discover major genetic cause of colorectal cancer

... CHICAGO -- About one-third of colorectal cancers are inherited, but the genetic cause of ... of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all ... is present in 10 to 20 percent of patients with colorectal cancer. The findings strongly suggest that the ...

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Colorectal in Biological Technology

Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update

... promising Phase 2 picoplatin data from our colorectal and prostate cancer programs. These data further ... by the end of this year. colorectal Cancer (CRC) : Presented new progression-free ... cell lung cancer and Phase 2 trials in metastatic colorectal and castration-resistant (hormone refractory) ...

Laboratory Test May Predict Effectiveness of ERBITUX(R) for Individual Colorectal Cancer Patients

... effectiveness of cetuximab (ERBITUX(R)) on the colorectal cancer cells of individual patients. Results from the study show that of the 54 primary colorectal cultures tested, eight percent were responsive to ... reported clinical response rate for cetuximab in colorectal carcinoma patients (11 percent). A predictive ...

Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology

... KRX-0401 in Advanced Renal Cell Carcinoma, colorectal Cancer and Gastrointestinal Stromal Tumors (GIST) ... of patients with advanced renal cell carcinoma, colorectal cancer and GIST. Abstracts selected for ... 2:00pm - 6:00pm (Level 2, West Hall C) colorectal Cancer Sunday, May 31 st , 2009: ...

Beyond associations: Colorectal cancer culprit found

... Genetics plays a key role in determining risk for colorectal cancer, the second leading cause of ... genetic variation associated with the risk of colorectal cancer and its functional implications, shedding ... down the genes that underlie diseases such as colorectal cancer is extremely difficult, owing to the ...

Poniard Pharmaceuticals to Present Final Data from Picoplatin Phase 1 Clinical Trials at American Association for Cancer Research's 100th Annual Meeting

... -- Phase 1 Data from colorectal Cancer and Oral Picoplatin Trials To Be Presented ... data from its Phase 1 trial of picoplatin in colorectal cancer (CRC) and bioavailability data from its ... 5-fluorouracil and leucovorin (FOLPI) for colorectal cancer (CRC): Comparison of two picoplatin ...

ScreenCancer Adds InSure(R) FIT(TM) Colorectal Cancer Screening Test to European Cancer Screening Program

... it has added the InSure(R) FIT(TM) take-at-home colorectal cancer screening test to its European ... risk. "We are pleased to provide annual colorectal cancer screening with InSure FIT to our ... shown to be highly effective in helping to detect colorectal cancers earlier, and, we believe, is the easiest ...

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Colorectal in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... reacts with a conserved epitope of the 40kD CDX2 protein localized in the nucleus. It exclusively marks nuclei of colonic epithelial cells and colorectal cancers on formalin-fixed, paraffin-embedded tissue sections. Therefore clone CDX2-88 may be used in identifying metastatic colon ....
Company:BioGenex

microRNA Expression Profiling - Comprehensive Service from LC Sciences

Description:... J.M., He, Y., Leary, R.J., Pagliarini, R., Diaz, L.A., Jr., Sjoblom, T., Barad, O., Bentwich, Z., Szafranska, A.E., Labourier, E. et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci USA 103, ....
Company:LC Sciences

Human / Mouse / Rat Blood Vessels (CD31 / Von Willebrand Factor (vWF)) IHC staining Kit from CHEMICON

Description:... for the identification of angiogenesis in several types of malignancies such as lung (Giatromanolaki et al., 1996), breast (Horak et al., 1992) and colorectal cancer (Takebayashi et al., 1996). CHEMICONs monoclonal antibody to CD31 is very specific for the staining of vascular endothelial cells in normal ...
Company:CHEMICON
Colorectal in Biological Definition

Cancer

... , multiple myeloma , brain tumor , breast cancer , cervical cancer , colorectal cancer - in the colon , rectum , anus , or appendix , esophageal ... test the following: acupuncture to reduce the symptoms of advanced colorectal cancer , combination chemotherapy plus radiation therapy with or ...
Colorectal in Biological Dictionary

Frameshift Mutation

... mutations occurred exclusively in MSI-H colorectal cancer cell ... The frameshift ... mutations occurred exclusively in MSI-H colorectal cancer cell ... In contrast, no frameshift mutation was found in 60 MSI-negative colorectal and ... Frameshift mutation in the hRAD50 ...

Screening

... information summary about tests used to detect or screen for colorectal cancer. ... Studies show that screening for colorectal cancer helps ... ... Online background screening investigation for ....

MSH2

... MSH2 is a gene commonly associated with Hereditary nonpolyposis colorectal cancer. ... MSH2 and ATR form a signaling module and regulate two ... Search: Summary Information ... Medline Search: hereditary nonpolyposis colorectal cancer AND ( msh2 or hnpcc1) (PubMed) ... Immunohistochemical ...

Colon

... and salt from solid wastes before they are eliminated from the body. colorectal cancer, also called colon cancer or large bowel cancer, includes ... ... Features information about colon cancer, also known as colorectal cancer. Includes illustrations, definition, causes, symptoms, signs and ...

Wildtype

... from the wildtype . ... Findings from three studies demonstrate the increased efficacy of Erbitux® (cetuximab) in patients with metastatic colorectal cancer (mCRC) who have a wild-type ... Britannica online encyclopedia article on wild type (genetics), ... ... Aspects of the topic ...

Small intestine

... bowel, is a cancer of the small intestine . It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer and colorectal cancer. The small intestine is a long coiled tube located in the abdominal cavity. ... In the small intestine , the epithelial cells ...
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