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Clostridium in Medical News

ViroPharma Announces Initiation Of Non-Toxigenic Clostridium Difficile Phase 1 Program

... Phase 1 clinical trial for NTCD (non-toxigenic clostridium difficile ), a novel treatment approach for preventing recurrent clostridium difficile infections (CDI). NTCD contains the ... patients taking antibiotics." About clostridium difficile One of the most serious problems ...

ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride

... infections of the gastrointestinal (GI) tract, clostridium difficile infection (CDI) and enterocolitis ... Vancocin is the only approved product to treat clostridium difficile -associated pseudomembranous colitis, ... and devastating hospital-acquired infections. clostridium difficile infection (CDI) can be severe, and ...

Cepheid Receives FDA Clearance for First On-Demand Molecular Diagnostic Test for Clostridium difficile Infection

... 45-minute detection of the bacterium that causes clostridium difficile infection (CDI). The Xpert C. ... cleared for the direct detection of toxigenic clostridium difficile from stool specimens. The test targets ... gene is the critical component of all toxigenic clostridium difficile strains -- including the epidemic ...

ViroPharma Announces Meeting of FDA Advisory Committee for Pharmaceutical Science and Clinical Pharmacology on Bioequivalence Recommendations for Oral Vancomycin Hydrochloride Products

... Vancocin is the only approved product to treat clostridium difficile -associated pseudomembranous colitis, ... and devastating hospital-acquired infections. clostridium difficile infection (CDI) can be severe, and ... to bioequivalence for Vancocin." About clostridium difficile One of the most serious problems ...

BD Announces FDA 510(k) Clearance of Novel Molecular Assay to Diagnose Clostridium difficile Infections

... detection of the Toxin B gene found in toxigenic clostridium difficile, the bacterial pathogen responsible for clostridium difficile infection (CDI). It is the first CDI ... that allows same-day identification of toxigenic clostridium difficile," said Thomas Davis, M.D., Ph.D., ...

Current Concepts in Clostridium difficile Infection: A Focus on Geriatric and Pediatric Patients

... N.J., Dec. 17 /PRNewswire/ -- Management of clostridium difficile infection (CDI) in geriatric and ... series entitled Current Concepts in clostridium difficile Infection . The third issue of this ... released and is entitled Current Concepts in clostridium difficile Infection: A Focus on Geriatric and ...

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Clostridium in Medical Technology

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

... 3 clinical study of fidaxomicin in patients with clostridium difficile infection (CDI) were presented today ... and did not have a recurrence. About clostridium Difficile Infection CDI has become a ... enzyme RNA polymerase, resulting in the death of clostridium difficile . The narrow spectrum profile of ...

Optimer Pharmaceuticals Receives Production Patent for Lead Product Candidate Fidaxomicin

... Phase 3 clinical trial for the treatment of clostridium difficile infection, or CDI. (Logo: ... enzyme RNA polymerase, resulting in the death of clostridium difficile . The narrow spectrum profile of fidaxomicin may eradicate clostridium difficile selectively with minimal disruption to ...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... Vancocin is the only approved product to treat clostridium difficile -associated pseudomembranous colitis. ... care facilities across the United States. clostridium difficile infection (CDI) can be severe, and ... pseudomembranous colitis caused by clostridium difficile and enterocolitis caused by ...

BD Announces CE Marking of a New Molecular Test to Diagnose Patients with Clostridium difficile Infections

... assay for the rapid diagnosis of patients with clostridium difficile infection (CDI). It is the first ... Directive for the identification of toxigenic clostridium difficile directly from stool specimens, the BD ... control interventions to prevent transmission of clostridium difficile to other patients. Until now, rapid ...

Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria

... oritavancin, to that of other antibiotics against clostridium difficile bacteria. Results are being presented ... Vitro Susceptibility of Genotypically Distinct clostridium difficile Strains to Oritavancin," researchers ... Vancomycin and Oritavancin Against Epidemic clostridium difficile Spores," researchers compared the ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... of destructive intestinal toxins caused by clostridium difficile (C. difficile) bacteria. C. ... session 229 titled, "New Agents Active Against clostridium difficile" at the 47th Annual ... to the further development of REP3123." About clostridium difficile C. difficile is a Gram-positive ...
Clostridium in Medical Products

Bartels® C. Difficile Toxin A Antigen EIA with Controls

Description:... Bartels clostridium difficile Toxin A Enzyme Immunoassay (EIA) is intended for the qualitative detection of clostridium difficile Toxin A in human faecal specimens as an aid in the diagnosis of clostridium difficile-associated ....
Company:Trinity Biotech

Clearview C. Diff A

Description:... Clearview C. Diff A is a one-step test for the direct qualitative detection of clostridium difficile toxin A from fecal ....
Company:Inverness Point of Care

Giardia lamblia II EIA

Description:... and monoclonal/polyclonal antibody-based ELISA tests for the detection of enteric pathogens in fecal specimens. Our line includes products for clostridium difficile, Entamoeba histolytica, Giardia, Cryptosporidium and fecal leukocyte ....
Company:Inverness Medical Innovations

Entamoeba Histolytica

Description:... and monoclonal/polyclonal antibody-based ELISA tests for the detection of enteric pathogens in fecal specimens. Our line includes products for clostridium difficile, Entamoeba histolytica, Giardia, Cryptosporidium and fecal leukocyte ....
Company:Inverness Medical Innovations

C. Diff-CHEK-30

Description:... DIFF CHEK-30 is a rapid ELISA test for clostridium difficile antigen that provides 100% negative predictive value and 99% sensitivity. That means the laboratory can quickly, easily and ...
Company:Inverness Medical Innovations

Cryptosporidium

Description:... and monoclonal/polyclonal antibody-based ELISA tests for the detection of enteric pathogens in fecal specimens. Our line includes products for clostridium difficile, Entamoeba histolytica, Giardia, Cryptosporidium and fecal leukocyte ....
Company:Inverness Medical Innovations
Clostridium in Medical Dictionary

Botulism

... containing toxins produced by the bacillus clostridium botulinum. Botulism Definition: Botulism ... rare but serious illness caused by the bacterium clostridium botulinum. The bacterium may enter the body ... caused by toxin produced by bacteria called clostridium botulinum. The toxins that this bacterium ...

Clostridium

... clostridium : A group of anaerobic bacteria ( bacteria ... absence of oxygen ). There are 100+ species of clostridium . clostridium botulinum is found in soil and untreated water ...

Gas gangrene

... gangrene ( tissue death ) usually caused by clostridium perfringens (see also necrotizing subcutaneous ... gangrene occurs as a result of infection by clostridium bacteria that, under anaerobic (low oxygen ... with certain types of bacteria , such as clostridium . It typically occurs at the site of a recent ...

Lockjaw

... is caused by infection with the bacterium clostridium tetani. One of the reasons that this organ ism ... nervous system caused by the toxins of clostridium tetani. This immunization protects against ... infectious disease , often fatal, caused by a clostridium tetani bacteria . The bacteria usually enters ...

Tetanus

... nervous system caused by the toxins of clostridium tetani. Tetanus is not a contagious ... infectious disease , often fatal, caused by a clostridium tetani bacteria . The bacteria usually enters ... is caused by infection with the bacterium clostridium tetani. One of the reasons that this organ ism ...

Campylobacter

... include Shigella , Salmonella , Campylobacter , and Yersinia. clostridium difficile produces a toxin that can cause severe diarrhea . ... Staphylococcus, complobacter jejuini, campylobacter iosis, and clostridium perfringens. Each of these comes primarily from eating meat, and ...

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Clostridium in Biological News

Monash scientists debug superbug

... ways to genetically modify the bacterium clostridium difficile and solved the mystery surrounding its ... for more than a decade. Dr Lyras said strains of clostridium difficile are found in almost every hospital in ... show that in the US, more people die from clostridium difficile infections than all other intestinal ...

Newly discovered reactions from an old drug may lead to new antibiotics

... the way selenoproteins are made can halt the growth of the super bug clostridium difficile and Treponema denticola , a major contributor to gum disease. Infections of clostridium difficile (commonly known as C-diff) lead to a spectrum of illnesses ...

Mass Biologic Labs/UMass Med School and Medarex license C. difficile monoclonal antibody to Merck

... human monoclonal antibody combination developed to target and neutralize clostridium difficile toxins A and B, for the treatment of C. difficile infection ... to both toxins A and B and protection from disease or relapse. About clostridium difficile infection (CDI) C. difficile is a spore-forming bacterium ...

Scientists unlock the secrets of C. difficile's protective shell

... detailed structure of a protective 'jacket' that surrounds cells of the clostridium difficile superbug, and which helps the dangerous pathogen stick to human ... analyse the areas where the two proteins link together in the layer. clostridium difficile is a bacterial pathogen that is present naturally in the gut of ...

Transportation fuels of the future: Nottingham leads the way

... Molecular Microbiology, and a world expert in the genetic modification of clostridium bacteria, will be developing a process for the large scale production of ... some world beating technologies which will allow us to generate the clostridium strains required." The research will be carried out in collaboration ...

Advance offers revolution in food safety testing

... can detect such important food-associated bacteria as Salmonella and clostridium perfringens, responsible for diarrheal illnesses; Bacillus cereus, ... by vomiting and diarrhea, and often referred to as stomach flu, and clostridium botulinum, which causes toxin-induced botulism, characterized by ....
Clostridium in Biological Technology

BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing.

... by totally eradicating all 5.4 million spores of clostridium difficile (C.diff) present in this test in 10 ... Status Among All Disinfectants. clostridium difficile (C.diff) is the most difficult to ... health care arena are ineffective at eliminating clostridium difficile spores. This is one reason why hospital ...

BioNeutral's Ygiene(TM) Hospital Grade Antimicrobial Demonstrates a 99.9997% Kill Rate Against Clostridium Difficile Spores (C.diff) in Independent Lab Pre-testing Phase

... Disk Carrier test starting with 5.5 million clostridium Difficile (C.diff) spores, BioNeutral's ... delivered an amazing 99.9997% kill. clostridium Difficile, an extremely dangerous and difficult ... compounds which are ineffective at eradicating clostridium Difficile spores, resulting in a serious unmet ...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

... 3 clinical study of fidaxomicin in patients with clostridium difficile infection (CDI) were presented today ... and did not have a recurrence. About clostridium Difficile Infection CDI has become a ... enzyme RNA polymerase, resulting in the death of clostridium difficile . The narrow spectrum profile of ...

Cepheid Announces Symposium Speakers and Program Highlights for 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

... C. difficile Diagnostic test for clostridium difficile infection ... assay and culture in the diagnosis of clostridium difficile infection (CDI) Dr. Kathleen ... amplification tests for the routine detection of clostridium difficile infection Dr. Andrej ...

ViroPharma Provides Update on Upcoming FDA Advisory Committee Meeting to Discuss Bioequivalence of Locally Acting Gastrointestinal Drugs

... in GI physiology observed in patients with clostridium difficile infection make healthy gut ... http://www.viropharma.com/OGDpetition/ . About clostridium difficile One of the most serious problems ... is hospital-acquired infections (HAIs). clostridium difficile infection is one of the most common and ...

Viropharma Comments On Upcoming FDA Advisory Committee Meeting

... do not pose as great a risk to patients." About clostridium difficile One of the most serious problems ... is hospital-acquired infections (HAIs). clostridium difficile infection is one of the most common and ... in diseases including cytomegalovirus (CMV) and clostridium difficile. For more information on ViroPharma, ...
Clostridium in Biological Products

TargeTron Gene Knockout System from Sigma-Aldrich

Description:... Gene knockout using the TargeTron system has been validated in a broad range of bacterial strains such asEscherichia coli, Staphylococcus aureus, clostridium perfringens, Shigella flexneri, Salmonella typhimurium,andLactococcus lactis. The system may be modified for use in additional organisms. Each ...
Company:Sigma-Aldrich
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