Researchers solve first structure of a key to intact DNA inheritance
... scientists capture the first structure ever solved of a segrosome complex that partitions and divides DNA.
A protein called ParR connects with a centromere
DNA site, a round string of DNA repeats in the plasmid, to form the segrosome complex, which then completes itself by attracting filaments of another ...
Centromere in Medical Products
Fluorescent HEp-2000 ANA
Features:... mitotic cells
Clear pattern identification
Ready-to-use pattern controls and conjugates
Positive pattern controls for: - homogeneous - centromere
- SS-A/Ro - speckled - nucleolar
Titratable control referenced to the WHO standard 66/233 for ...
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Centromere in Biological News
Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation
... from the centre of the cell to the poles. The centromere
is the area of the chromosome that directs this ... along the protein track. The location of the centromere
on the chromosome is marked by the presence of a ... of the cell to orchestrate the assembly of the centromere
was not understood - until now.
Using a ...
Centromeres cross over, a lot
... called shelterins and by DNA methylation. The centromere
has no shelterin, but it is methylated. Knockdown ... methyltransferases increased recombination at the centromere
by about 50%, and decreased centromere
length, possibly because of misalignment between ...
CSHL researchers explain process by which cells 'hide' potentially dangerous DNA segments
... components," explains Joshua-Tor, "there has been a longstanding debate over how the RITS complex initially gets recruited to the regions at the centromere
that are destined to become heterochromatin."
At first, scientists thought that the siRNA molecules acted as guides to recruit RITS. After ...
Exploring the dark matter of the genome
... centromeres and telomeres. In a typically bow-tie-shaped chromosome, the centromere
is the knot. Centromeres play a crucial role in controlling chromosome ... -- that is, from one end of the chromosomes to the other -- including the centromere
in the middle." Obtaining a more complete picture of the sequence of ...
Regulating the nuclear architecture of the cell
... -- chromatin structures best known for limiting, by their diminishing length, how many times a cell can replicate. Heterochromatin also flanks the centromere
in the central region of the chromosome, the chromatin structure that plays a crucial role in chromosome segregation during cell division. What other ...
One-dimensional diffusion accelerates molecular motors
... Prof. Jonathon Howard and Stefan Diez at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden. The motor protein MCAK (Mitotic centromere
Associated Kinesin) goes into action at the end of microtubules where it disassembles them. This is in contrast to most other motor proteins, which ...
15-year hunt finds cause of pseudothalidomide syndrome
... together, ensuring that the two copies are lined up together at the center of the dividing cell. Once lined up, tiny molecular "motors" attach to the centromere
of each copy and pull the original and the new copy away from each another as division proceeds.
However, in cells from people with Roberts ...
Found: Missing sequence of the human Y chromosome
... that they have successfully cloned and characterized a
previously intractable DNA sequence: a 554-kilobase-pair genomic
segment near the centromere
of the human Y chromosome. This sequence
contains eight putatively active genes that could be implicated in
sex-associated height differences and ...
Centromere in Biological Technology
Rice Centromere, Supposedly Quiet Genetic Domain, Surprises
... significant step," says Jiang. "This is the first centromere
to be sequenced at this level for any higher organism."
of rice, says Jiang, lent itself to sequencing ... a surprise, says Jiang. The newly discovered rice centromere
genes, whose functions are unknown, belie the ...
Centromere in Biological Products
LNA-ISH Cytogenetics - Human centromere alpha satelliteISH probes from Exiqon
Description: Exiqons LNA technology enables sensitive, fast and specific detection of chromosomal sequences directly on intact chromosomes. Short hybridisation time ( Works on fixed cells and chromosome spreads Multiplex capability Available with different tags Pre-validated probes Probes available ...
Centromere in Biological Definition
... The centromere
is a region of a eukaryotic chromosome where ... images of chromosomes.
In most eukaryotes, the centromere
has no defined DNA sequence . It typically ... inheritance plays a major role in specifying the centromere
in most organisms. The daughter chromosomes will ...
... parts of the chromosome after S phase . (2) centromere
. The point where the two chromatids touch, and ... in the cell's nucleus. Each chromosome has one centromere
, with one or two arms projecting from the ... is never expressed. It is located around the centromere
and usually contains repetitive sequences.
... gamete nuclei come together and pair up. They have same lengths, same centromere
positions and in most cases same number of genes arranged in linear order. ... centromeres , lining up the bivalents along the equator so that each centromere
is equidistant above and below the equator. The lining along the equator ...
... a chromosome . An important reference point along this string is the centromere
; the distance from a gene to the centromere
is referred to as the gene's locus or map location. A chromosomal region ...
... (Y or W).
Mammalian X-chromosome inactivation is initiated from the X inactivation centre or Xic , usually found near the centromere
. The centre contains twelve genes, seven of which code for proteins , five for untranslated RNAs , of which only two are known to play an active ...
... of DNA condensation. (1) Single DNA strand. (2) Chromatin strand ( DNA with histones ). (3) Condensed chromatin during interphase with centromere
. (4) Condensed chromatin during prophase . (Two copies of the DNA molecule are now present) (5) Chromosome during metaphase .
Two distinct ...
... After they have been pulled apart by the mitotic spindle , chromatids are called "chromosomes". Sister chromatids are joined at a point called the centromere
. In non-gametic, non-dividing human cells, there are 23 pairs of chromosomes, thus 46 chromosomes. When it is ready to divide, each chromosome will ...
... the result can be a duplication of genes on one chromosome and a deletion of these on the other. If they break and rejoin on opposite sides of the centromere
, the result can be one chromosome being lost during cell division . If homologous chromosome are not perfectly aligned an unequal crossover may ...
... in the cell. Identical chromosomes (called sister chromosomes) are attached to each other at a DNA element present on every chromosome called the centromere
. A protein called cohesin acts as a glue joining two sister chromosomes (a.k.a. sister chromatids) along their lengths. When chromosomes are paired ...
... spindle is formed by the centrosomes as they move apart.
Some of the spindle's microtubules attach to the kinetochores that assemble on the centromere
portion of the chromosomes and then pull the chromosomes into alignment along the center of the spindle. Once all the chromosomes are aligned ...
Centromere in Biological Dictionary
... A centromere
is a region of DNA typically found near the ... division as the point of mitotic spindle. centromere
( ) n. The most condensed and constricted region ... the spindle fiber is attached during mitosis centromere
protein E edit ...
... centromere; "an acrocentric chromosome" ... centromere
( ) n. The most condensed and constricted region ... including ... acrocentric adj. Having the centromere
located near one end of the chromosome so that ... /ac·ro·cen·tric/ (-sen'trik) having the centromere
toward ... Acrocentric . Definition(s) ... ...
... distance between a ship's center of gravity and its metacenter, for metacentric adj. Of or relating to a metacenter. Genetics. Having the centromere
in the median position so that the arms are of equal length metacentric . Definition from Wiktionary, a free dictionary. Jump to: navigation, ...
... or intense concentration: "the cunning exploitation of loci of Locus (genetics) Short and long arms Chromosome components: (1) Chromatid (2) centromere
(3) Short arm (4) Long arm Example of bands In the fields of home | products & services | news | contact us | careers. Copyright © 2008 Locus ...
... videos, listen to free streaming mp3s, & read Loci's blog. Locus (genetics) Short and long arms Chromosome components: (1) Chromatid (2) centromere
(3) Short arm (4) Long arm Example of bands In the fields of loci [L.] plural of locus . ... Why does linkage between loci tend to decrease ...
... Scientists report that they have successfully cloned and characterized a previously intractable, 554- kilobase -pair genomic segment near the centromere
of the human Y ... Inverse polymerase chain reaction (Inverse PCR) is a variant of the polymerase ... One limitation of conventional PCR is ...
... in mitosis, except no ... ... five centromeric signals can be detected per interkinesis nucleus (Fig. 6B,C) ... We found only one separated centromere
in 88 scored smg7 interkinesis nuclei. ... ...
... alleles at corresponding chromosomal loci; ... One strand of a replicated chromosome as ... A single strand by itself with it's own centromere
is a chromosome and not a chromatid. ... heterozygous ... A simple kind of learning involving a loss of sensitivity to ... heterozygous ...
... spirem, and ... Offers a pictorial tour of the process of cell division. ... the onset of anaphase, each daughter chromosome possesses one centromere
and one ... Brief review of mitosis, a comparison with meiosis and step-by-step walk ... Telophase—the groups of daughter chromosomes are ...
... this word ... Acentric - Definition of Acentric at Dictionary.com a free online dictionary ... ACENTRIC - 3 dictionary ... lacking a centromere
< acentric chromosomes> ... ...