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Castration in Medical News

Did Medicare Reimbursement Changes Affect Prostate Cancer Treatment?

... link between less drug therapy and more surgical castration MONDAY, April 7 (HealthDay News) -- ... Coincidentally or not, the use of surgery -- castration -- to accomplish that same goal started to ... the drug therapy -- sometimes called hormonal castration -- and surgery are virtually equivalent in their ...

Hormone refractory prostate cancers more likely to spread to other organs

... resistant over time. These hormone refractory or castration resistant cancers can grow despite surgical or ... Reiter said. We started noticing that the castration resistant prostate cancer models in the lab ... to find that it was not only overexpressed in castration resistant cancers but also in invasive cancers ...

Androgen Production Continues in Prostate Cancer Tumors

... cancer growth. Androgen therapy, which involves the use of surgical castration or medical castration with testosterone-blocking drugs, does extend survival time for patients, ...

How advanced prostate cancer becomes resistant to androgen-deprivation therapy

... testosterone the hormone that fuels prostate-cancer growth via surgical castration (orchiectomy) or medical castration with testosterone-blocking drugs. While such therapy buys time for ...

Revised AVMA Policy on Castrating and Dehorning Cattle Provides Additional Guidance for Managing Pain

... about identifying and ameliorating pain experienced by cattle during castration and dehorning. "Individual practitioners are encouraged to achieve pain ... . Backgrounders on castration and dehorning have been compiled by the AVMA Animal Welfare Division and ...

AUA Foundation announces 2009 Research Scholar Program award winners

... of Clear Cell Renal Cell Carcinoma Smitha Dutt, PhD, University of California, Davis School of Medicine Role of Trefoil Factor 1 (TFF1) in castration Resistant Prostate Cancer Amit Gupta, MD, MPH, Memorial Sloan-Kettering Cancer Center Significance of Prostate-Specific Antigen and Kallikrein 2 ...

Poniard Pharmaceuticals Announces Appointment of Greg Weaver as Chief Financial Officer

... Clinical trials of intravenous picoplatin include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic colorectal and castration resistant prostate cancers (also known as hormone refractory prostate cancer), as well as a clinical trial of oral picoplatin in solid tumors. For ...

Why prostate cancer patients fail hormone deprivation therapy

... Institute. Since 1941, doctors have taken advantage of this dependency to battle prostate cancer by depriving patients of androgens, either by castration or chemical methods. For most patients, this hormone deprivation therapy causes tumors to shrink, sometimes dramatically. However, it's never a ...

Annual Congress European Association of Urology: highlights in Stockholm

... plenary sessions will focus on hot topics in prostate cancer. Providing the SIU lecture is Dr. Martin Gleave (Vancouver, Canada) who will discuss castration resistant prostate cancer with emphasis on new therapeutic approaches. Sub-plenary sessions will continue in the afternoon meetings focusing on ...

New research may show why some prostate cancer recurs after treatment

... becoming resistant to hormone suppression. Research in the field has focused on understanding the mechanisms used by these cancer cells to become castration resistant. Investigators Peter Nelson, M.D., Elahe Mostaghel, M.D., Ph.D., and Bruce Montgomery, M.D. from the Fred Hutchinson Cancer Research ...
Castration in Medical Technology

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

... for a reversible reduction of serum testosterone to the level of castration in adult men suffering from sexual deviations. Developed by Debiopharm, ... safety profile. Triptorelin decreased serum testosterone to the level of castration in all patients. Concurrent with the decrease in testosterone levels, the ...

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

... for a reversible reduction of serum testosterone to the level of castration in adult men suffering from sexual deviations. Developed by Debiopharm, ... safety profile. Triptorelin decreased serum testosterone to the level of castration in all patients. Concurrent with the decrease in testosterone levels, the ...

Interim Phase 1/2 Data of Ipilimumab in Prostate Cancer Presented at American Society of Clinical Oncology Annual Meeting

... (Abstract #5004) "These initial data in patients with metastatic castration resistant prostate cancer demonstrated preliminary anti-tumor activity, ... is routinely used for palliative treatment in patients with metastatic castration resistant prostate cancer and bone metastases, and these data encourage ...

Research Explains How Advanced Prostate Cancer Becomes Resistant to Androgen-Deprivation Therapy

... -- the hormone that fuels prostate-cancer growth -- via surgical castration (orchiectomy) or medical castration with testosterone-blocking drugs. While such therapy buys time for ...

Salvacyl(R), Developed by Debiopharm, is Launched in two European Countries

... hormone (GnRH) agonist analogue. The product will be prescribed for the reversible reduction of serum testosterone to the level of castration in order to lower sexual drive in adult men suffering from sexual deviations. "This is a great accomplishment for Debiopharm. Salvacyl(R) is ...

Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology

... of Ipilimumab in Prostate -- "Phase 1 trial of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC)" (Abstract #5004, New Targeted Strategies for Patients with Prostate Cancer Session) -- Oral presentation ...

Medivation's MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial

... "While these results are still preliminary, the declines in PSA observed at these lowest doses are encouraging and provide proof of concept that castration resistant prostate cancers can still be sensitive to alternative hormone therapies like MDV3100," said the study's principal investigator Howard ...

Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference

... synthesis results in high response rate in castration resistant prostate cancer The Phase I/II trial ... to have activity in post-docetaxel castration resistant prostate cancer The Phase II trial of ... administered orally, once daily, to patients with castration resistant prostate cancer who have failed ...

AEterna Zentaris Reports Positive Results with Cetrorelix in BPH for Japanese Phase 2a Trial

... profile Reduction of testosterone concentration was maintained above castration level Japanese partner Shionogi initiates Phase 2b trial QUEBEC CITY, ... concentration in blood, which did not reach or remain at the castration level. Additionally, none of the dosage regimens tested caused a ...

Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session

... Inhibition of androgen synthesis results in a high response rate in castration refractory prostate cancer: A Phase II clinical trial The Phase I/II ... CYP450c17 enzyme inhibitor appears to have activity in post-docetaxel castration refractory prostate cancer patients The Phase II trial is being ...

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Castration in Medical Dictionary

Castration

... castration : Removal of the sex glands , usually used to ... For: search help Printer-Friendly Format ... castration In this procedure, testicles are removed and the ... to insert testicle-shaped prostheses. castration Removal or destruction of the testicles or ...

Orchiectomy

... . Aromatase inhibitors.[6-8] ... Testicles ( orchiectomy or castration ) Ovaries ( oophorectomy ) in premenopausal women Ad renal gland ... levels are lowered either by surgical removal of the testicles ( castration , orchiectomy ) or by medication, prostate cancer can regress. There is ...

Atrophy

... symptoms associated with menopause , (2) treatment of vulva l and vagina l atrophy , (3) treatment of hypoestrogenism due to hypogonadism , castration , or primary ovarian failure, ... Possible side effects associated with chronic and prolonged use of topical corticosteroids include skin ...

Benign Prostatic Hyperplasia

... congenital disorders that affect the urinary tract ... When testosterone levels are lowered either by surgical removal of the testicles ( castration , orchiectomy ) or by medication, prostate cancer can regress. There is no known association with benign prostatic hyperplasia ( BPH ). ...

Genitalia

... genitalia . In psychoanalysis, a fetish is believed to represent a substitute for male genitalia , which women are imagined to have lost through castration . tub baths, certain additives to bath water, and some commercial douche s) permit the yeast to grow in the vagina . The discharge is moderate ...

Luteinizing hormone

...... Luteinizing hormone -releasing hormone (LH-RH) agonists Luteinizing hormone -releasing hormone (LH-RH) antagonists Anti - androgen s castration ( orchiectomy ) ... luteinizing hormone A hormone secreted by the anterior pituitary gland , responsible for stimulating ovulation in ...

Masturbation

... be a form of possession by spirits. Other myths have existed until more recent times, one being that epilepsy can be caused by masturbation with castration used as a ' treatment '. For many individuals, a cognitive reframing of masturbation to self-stimulation or self-pleasuring allows the ...

Mediastinum

... organ s in this area include the heart and its large blood vessels, the trachea , the esophagus , the bronchi , and lymph node s. medical castration ... Mediastinum The area between the lungs , bounded by the spine, breast bone, and diaphragm . Sputum Mucus or phlegm that is cough ed ...

Stye

... organ s in this area include the heart and its large blood vessels, the trachea , the esophagus , the bronchi , and lymph node s. medical castration ... Inflammation of a gland on the eyelid. Also called a stye . hormone A substance formed in an organ of the body and carried by body ...

Vulva

... symptoms associated with menopause , (2) treatment of vulva l and vagina l atrophy , (3) treatment of hypoestrogenism due to hypogonadism , castration , or primary ovarian failure, ... The main symptom of thread worms is itching around the anus or vulva . This is worse at night when the ...

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Castration in Biological News

Veterinarians developing model to help producers, vets make cattle more comfortable

... similar to a pedometer are a few of the tools K-State researchers are using to measure discomfort in cattle undergoing two routine procedures, castration and dehorning. Hans Coetzee, assistant professor of clinical sciences, is working with David Anderson, professor of clinical sciences, and Brad ...
Castration in Biological Technology

AEterna Zentaris Presents Data Supporting Evaluation of AEZS-108 in Prostate Cancer at ASCO Meeting

... - In virtually all patients with prostate cancer, tumor cells appear to express LHRH receptors; - Even tumors persisting or relapsing after castration or prolonged hormonal treatment with LHRH agonists retain the expression of LHRH receptors; - The continued expression of these ...

Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology

... "Initial Phase 2 experience of ipilimumab (IPI) alone and in combination with radiotherapy (XRT) in patients with metastatic castration resistant prostate cancer (mCRPC)" (Abstract #5138, Genitourinary Cancer - Prostate Session) S. Slovin - General poster from 2:00 p.m. to 6:00 p.m. ...

Poniard Pharmaceuticals to Present at the BIO CEO & Investor Conference

... Clinical trials of intravenous picoplatin include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic colorectal and castration resistant prostate cancers (also known as hormone refractory prostate cancer), as well as a clinical trial of oral picoplatin in solid tumors. For ...

Poniard Pharmaceuticals to Present Data from Phase 2 Clinical Trials of Picoplatin in Colorectal and Prostate Cancers

... in San Francisco. In February, updated data from the ongoing Phase 2 trial of picoplatin in patients with metastatic hormone refractory (or castration resistant) prostate cancer will be presented at ASCO's Genitourinary (GU) Cancers Symposium in Orlando, Fla. Presentation details are as ...

Sex Steroid Regulation of Vasopressin Levels Secreted by hNT Neurons*

... in rats. 7 In addition, the density of ADH nerve fibers is higher in male rats than in female rats. 8 ADH nerve-fiber density can be reduced by castration and restored to normal density following testosterone replacement therapy. 9 hNT Neurons and Alzheimers Disease Another topic in ...
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