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Carcinoid in Medical News

Lexicon Pharmaceuticals Provides Clinical Pipeline Update and Reports 2009 Second Quarter Financial Results

... of a Phase 2 study of LX1032 in patients with carcinoid syndrome," said Dr. Arthur T. Sands , ... (FDA), into a Phase 2a study in patients with carcinoid syndrome . The Phase 2 clinical trial is ... and its effects on symptoms associated with carcinoid syndrome. The study will include up to 28 ...

The AGA Foundation awards grant to Dr. Michael Choi to further his research on carcinoid tumors

... for young investigators interested in researching carcinoid or neuroendocrine tumors. Dr. Choi is an ... Terese Hartzheim (MTH) Foundation and Caring for carcinoid Foundation (CFCF) to fund this grant for ... the development, diagnosis and treatment of carcinoid and neuroendocrine tumors," said Sidney Cohen, ...

Carcinoid Cancer Foundation Sets Sights on Raising Awareness

... the only cancers that catch victims by surprise. carcinoid cancer can go undetected for many years. Over 90% ... diagnosed and treated for the wrong disease. carcinoid cancers are frequently diagnosed accidentally. carcinoid and related neuroendocrine tumors (NETs) grow ...

Indevus Pharmaceuticals Announces Definitive Merger Agreement With Endo Pharmaceuticals

... implant (in development for acromegaly and carcinoid syndrome), two of Indevus' primary product ... and sale for the treatment of acromegaly or carcinoid syndrome. The tender offer is expected to ... the octreotide implant for acromegaly and carcinoid syndrome, and pagoclone for stuttering. ...

Lexicon Initiates Phase 2 Clinical Trial of LX2931 in Patients With Rheumatoid Arthritis

... 2 clinical trials, LX1031 for irritable bowel syndrome and LX1032 for carcinoid syndrome. Furthermore, LX4211 for diabetes has recently completed dosing ... currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which ...

Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers

... address unmet needs in the treatment of adults with small cell cancer and carcinoid cancer. It can also potentially treat children with neuroblastoma, Wilms' ... from Phase I/II open label clinical trials, which included both SCLC and carcinoid cancer patients, found that the majority of patients responded to NTX-010 ...

Indevus Pharmaceuticals Announces First Quarter Fiscal 2009 Financial Results

... upon achievement of certain milestones related to NEBIDO(R) (in development for hypogonadism) and octreotide (in development for acromegaly and carcinoid syndrome), two of the Company's primary product candidates. The acquisition will be effected by means of a tender offer for all the outstanding ...

Endo Pharmaceuticals to Acquire Indevus Pharmaceuticals

... for hypogonadism, PRO 2000 for the prevention of infection by HIV and other sexually-transmitted pathogens, the octreotide implant for acromegaly and carcinoid syndrome, and pagoclone for stuttering. About Endo Pharmaceuticals Endo Pharmaceuticals is a specialty pharmaceutical company engaged in ...

Saturated Fats Linked to Cancer of Small Intestine

... study to examine the association between meat and fat intake and cancer of the small intestine. During the study, 60 adenocarcinomas and 80 carcinoid tumors of the small intestine were diagnosed among the participants, and an elevated risk for these cancers was associated with saturated fat intake, ...

Also in the Sept. 9 JNCI

... Experts Call for Renewed Efforts in Gastroenteropancreatic Neuroendocrine Tumors During a September 2007 summit on neuroendocrine and carcinoid tumor, clinicians and researchers presented the current standards of care and identified key areas that require investigation and development. ...
Carcinoid in Medical Technology

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

... gastrointestinal symptoms associated with carcinoid syndrome . LX1032 is designed to reduce serotonin production in patients with metastatic carcinoid tumors. Elevated levels of serotonin contribute ... new drug candidate for symptoms associated with carcinoid syndrome," said Philip Brown , M.D., J.D., ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... tumors (i.e., tumors that are associated with carcinoid syndrome due to the secretion of various hormones ... episodes associated with advanced carcinoid tumors and profuse watery diarrhea associated ... used to treat symptoms associated with metastatic carcinoid tumors (flushing and diarrhea) and vasoactive ...

Lexicon Presents Clinical Data on LX1032 for Carcinoid Syndrome at European Neuroendocrine Tumor Society Meeting

... gastrointestinal symptoms associated with carcinoid syndrome. The clinical studies, conducted to ... Phase 2 clinical trial of LX1032 in patients with carcinoid syndrome in the first quarter of 2009. A ... from March 5-7 in Granada, Spain. About carcinoid Syndrome and LX1032 ...

RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors

... Depot therapy on survival in pancreatic NET and carcinoid patients EAST ... mixture of tumors that include pancreatic NET and carcinoid tumors. The development of NET is not completely ... treat the diarrhea and flushing associated with carcinoid syndrome. The active ingredient in Sandostatin ...

Callisto Pharmaceuticals Completes Enrollment of Phase II Trial of Atiprimod in Neuroendocrine Cancer

... the debilitating symptoms of this disease. About carcinoid Cancer carcinoid tumors, or carcinoids, originate in ... the number increasing over the past 20-30 years. carcinoid tumors that metastasize to the liver have a poor ...

Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients

... grade neuroendocrine carcinoma (advanced carcinoid cancer). With the addition of the Robert H. Lurie ... to the Phase II trial of Atiprimod in advanced carcinoid patients signifies our continuing commitment to ... and have built significant reputations within the carcinoid community, which should substantially enhance the ...

Lexicon Pharmaceuticals Provides Clinical Pipeline Update and Reports 2009 First Quarter Results

... and Drug Administration (FDA), into a Phase 2a study in patients with carcinoid syndrome . Lexicon has identified the clinical trial sites for this ... currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which ...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... the endocrine (hormonal) system and the nervous system, and includes carcinoid tumors and pancreatic NETs. Treatment options for patients with NETs are ... octreotide has been used to treat symptoms associated with metastatic carcinoid tumors (flushing and diarrhea) and vasoactive intestinal peptide (VIP) ...

FDA Accepts Complete Response Submission to New Drug Application for NEBIDO(R)

... for hypogonadism, PRO 2000 for the prevention of infection by HIV and other sexually-transmitted pathogens, the octreotide implant for acromegaly and carcinoid syndrome, and pagoclone for stuttering. Safe Harbor Statement This press release contains forward-looking statements within the ...

Indevus Pharmaceuticals Announces PRO 2000 Found to Show Promise in Large HIV Prevention Study

... for hypogonadism, PRO 2000 for the prevention of infection by HIV and other sexually-transmitted pathogens, the octreotide implant for acromegaly and carcinoid syndrome, and pagoclone for stuttering. PRO 2000 PRO 2000 (a naphthalene sulfonate polymer) is under development as a topical vaginal ...
Carcinoid in Medical Definition

Pathology

... - 5-alpha-reductase deficiency - Hypogonadism - Delayed puberty - Precocious puberty Other Autoimmune polyendocrine syndrome - carcinoid syndrome - Laron syndrome - Psychogenic dwarfism - Androgen insensitivity syndrome - Progeria v • d • e ...
Carcinoid in Medical Dictionary

Carcinoid syndrome

... carcinoid syndrome . This syndrome is a combination of ... flushing of the skin and diarrhea . carcinoid syndrome -- a disease caused by abnormal cells ... excessive production of thyroid hormone ... carcinoid Syndrome and ...

Carcinoid tumor

... Since carcinoid tumor s are frequently indolent in growth, and ... of metastatic disease at diagnosis . carcinoid tumor s have been called " cancer s in slow ... other parts of the body. The prognosis of carcinoid tumor s is related to the specific growth ...

Gastrointestinal

... which extends from the mouth to the large bowel . Gastrointestinal carcinoid Tumor s (PDQ): Treatment Last Modified: 05/14/2004 General Information About Gastrointestinal carcinoid Tumor s ... Home Gastrointestinal Bleeding (GI Bleed) ...

MIBG

... MIBG is absorbed by carcinoid cells and damages them. Researchers are studying MIBG to see if it is ... radioactive iodine (I131), to lessen the symptoms of gastrointestinal carcinoid tumor s. Other types of treatment are being tested in clinical trials . ...

Tumor

... immunodeficiency syndrome ) attacks the body's immune system . carcinoid disease is sometimes called " cancer in slow motion" because it can lurk in the body for decades. Learn how carcinoid tumor s are different from more common cancer s. Neuro endocrine ...

Acromegaly

... of growth hormone and IGF-1 ( insulin growth factor) in acromegaly ; (2) suppression of severe diarrhea and flushing associated with malignant carcinoid syndrome ; ... cause increased blood creatinine levels include blockage of the urinary tract (such as by a kidney stone), heart failure , ...

Angioma

... of the blood vessels ( aneurysm or angioma ). A combination of symptoms caused by the release of serotonin and other substances from carcinoid tumor s of the gastrointestinal tract. Symptoms may include flushing of the face, flat angioma s (small collections of dilated blood vessels) of ...

Appendix

... its removal, spilling its contents into the abdominal cavity . Peritonitis or a generalized infection in the abdomen will occur. [57] Most carcinoid tumor s of the appendix are small, localized tumor s and simple appendectomy is the therapy of choice. The standard treatment is to remove ...

Autonomic neuropathy

... with autonomic neuropathy or GVHD. Zollinger-Ellison syndrome Nerve disorders like autonomic neuropathy or diabetic neuropathy carcinoid syndrome Following gastrectomy ( partial removal of the stomach ) High dose radiation therapy ... Common symptoms of diffuse autonomic ...

Bronchi

... s Bronchi al tumor s (which are slow-growing cancer s in the trachea or large bronchi , the large airway s of the lung), are most often carcinoid tumor s in children. Bronchi tis is inflammation of the bronchi , and is frequently complicated by mucous obstruction of those passageways. ...

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Carcinoid in Biological News

Society of Interventional Radiology Foundation awards $191,000 in grants

... Gaur, Harvard Medical School, Boston, Mass., "Hepatic Arterial Chemoembolization (HACE), Yttrium-90 Radioembolization and Drug-eluting Bead-HACE in carcinoid Metastases to the Liver." ...
Carcinoid in Biological Technology

Lexicon Initiates Phase 2 Clinical Trial of LX1032 in Patients With Carcinoid Syndrome

... gastrointestinal symptoms associated with carcinoid syndrome . LX1032 is designed to reduce serotonin production in patients with metastatic carcinoid tumors. Elevated levels of serotonin contribute ... symptoms experienced by patients with carcinoid syndrome who have become refractory to current ...

Lexicon to Present Clinical Data for LX1031 and LX1032 at Digestive Disease Week

... gastrointestinal symptoms associated with carcinoid syndrome . The presentations will take place at ... is entering a Phase 2 study in patients with carcinoid syndrome. For more information on these ... candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel ...

EntreMed Presents Interim Results for Phase 2 Carcinoid Tumor Study

... in patients with advanced or metastatic carcinoid tumors. The data were presented by principal ... NCD and Avastin(R) is well tolerated in advanced carcinoid tumor patients. The current analysis includes ... we should proceed with this combination." About carcinoid Tumors Carcinoids are tumors of neuroendocrine ...

Lexicon Files Investigational New Drug Application for LX1032 as a Potential Treatment for Carcinoid Syndrome

... symptoms associated with carcinoid syndrome. The initial Phase 1 clinical trial of ... may offer important benefits to patients with carcinoid syndrome, who have very limited treatment options." carcinoid syndrome is the result of ...

Lexicon to Provide Clinical Pipeline Update and Report Second Quarter 2009 Financial Results on July 28, 2009

... and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by Lexicon's research team. Lexicon has used its proprietary ...

Delcath Systems Granted Third Orphan Drug Designation

... the drug melphalan for the treatment of neuroendocrine tumors metastatic to the liver. The trial is treating patients with pancreatic islet-cell and carcinoid tumors at the National Cancer Institute in Bethesda, Maryland. Commenting on this orphan-drug designation, Richard L. Taney, President and CEO of ...

Lexicon Names Ajay Bansal Executive Vice President and Chief Financial Officer

... and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by Lexicon's research team. Lexicon has used its proprietary ...

Lexicon to Provide Clinical Pipeline Update and Report First Quarter 2009 Financial Results on April 28, 2009

... and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by Lexicon's research team. Lexicon has used its proprietary ...

Lexicon Pharmaceuticals 2008 Annual Report to Stockholders Available Online

... and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by the company's research team. The company has used its ...

Indevus Pharmaceuticals Announces Release of 2008 Annual Report

... for hypogonadism, PRO 2000 for the prevention of infection by HIV and other sexually-transmitted pathogens, the octreotide implant for acromegaly and carcinoid syndrome, and pagoclone for stuttering. Contact: Michael W. Rogers EVP and Chief Financial Officer (781) 861-8444 Robin ....
Carcinoid in Biological Dictionary

Intestine

... G ... structure of the intestine varies greatly in ... Small Intestine Cancer Key Terms: Adenocarcinoma , Angiosarcoma , Carcinogen , carcinoid , Leiomyosarcoma , Liposarcoma , Lymphoma , Malignant , In anatomy, the intestine is that tubular portion of the Gastrointestinal tract ... In ...
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