DNA Molecules Used To Assemble Nanoparticles
...particle complexes can be specifically targeted to cancer cells and are small enough to enter a diseased cel...e designed for imaging and the other for targeting cancer cells. Each of the dendrimers also carried a single-stranded, non-coding DNA synthesized by Choi. I...Viral DNA sequence a possible trigger for breast cancer
...irus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the ...arcoma virus, but what role this sequence plays in cancer development has remained unexplored. Katz and colleagues now show that this sequence is contained i...Association of herpesvirus with lung disorder questioned
...ion is associated with Kaposi's sarcoma, a type of cancer most commonly seen in some parts of Africa and southern Europe and in people infected with HIV. Primary pulmonary hypertension is characterized in part by vascular lesions in the lung, and may lead to heart failure. Some cases are associated with gen...Man and mouse share genome structures
...ntists understand regulatory mechanisms underlying cancer and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postdoctoral fellowship who works in the Harvard University laboratory of HHMI investigator Stuart L. S...Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemo...iation therapy was associated with improved breast cancer survival but not with overall survival. In this 20-year follow-up of the British Columbia trial, Jo...microRNA Expression Profiling - Comprehensive Service from LC Sciences
...ncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9(6), 435-443. (3) Cummins, J.M., He, Y., Leary, R.J., Pagliarini, R., Diaz, L.A., Jr., Sjoblom, T., Barad, O., Bentwich, Z., Szafranska, A.E., Labourier, E. et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci USA 103, ...Cell Invasion Colorimetric Assay Kit from CHEMICON
...t membrane) surrounding the blood vessels to allow cancer cells to invade.The CHEMICON Cell Invasion Assay Kit provides an efficient system for evaluating the invasion of tumor cells through a basement membrane model. The kit utilizes ECMatrix, a reconstituted basement membrane matrix of proteins derived fr...Serum Biomarker Chip from Whatman, Inc
...iomarker chip to profile the relative abundance of cancer serum proteins. An antibody chip containing 120 human cancer serum biomarker-specific antibodies. A research tool that enables biomarker discovery scientists to ...HER2plus Control Slides from European Collection of Cell Cultures (ECACC)
...of paraffin wax sections of formalin fixed, breast cancer cell lines; MDA-MD-361, T47D, MCF and the ovarian cell line SKOV-3. This range of cell lines provides a gradation of HER2 protein level expression around the clinically significant range. When used as part of a validated assay system, the HER2plus co...Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
...predisposition tomultifactorial diseases including cancer and cardiovascular and infectiousdiseases. The sequence changes also constitute the genetic basis for manynondisease traits, such as obesity and a persons response to drugs. Moreover,single nucleotide polymorphisms (SNPs) are valuable genetic markers...Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue
...sed by anumber of human colon cancers 6 and colon cancer cell lines includingHT29, MC26 and NCIH716. 7,8 S...ble lesions prior to the overtdevelopment of colon cancer and are therefore useful for evaluating the presenceor absence of GRP receptor expression. In situ ...Constructing Directional cDNA Libraries from Limited Amounts of RNA
... PCR products. We usedthe kit to create an ovarian cancer cDNA library from tissue isolated bylaser-capture ...Is goal of identifying the molecularsignature of a cancer cell. Construction of cDNA Libraries Fig.2 First-strand cDNA synthesis is p...Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
...he hallmark of occupational- and lifestyle-related cancer is tissuespecificity. Human exposures to carcinogens result in particular types of cancerat predictable sites; tobacco smoke, arsenic, and ionizing radiation all producetheir own unique kinds of cancers in preferred tissues. Tissue specificity isalso...... Vaccination against cancer The results of Vaccination against cancer [11], which have recently been the subject of extensive press coverage, were only possible a...Use of Cellular Phones associated with Increased risk of Brain Tumors
... suggests that there is an increased risk of brain cancer in the areas of highest exposure in patients using digital telephones (Case Control Study on Radiology work, Medical X-Ray Investigations, and Cellular Telephones as Risk Factors for Brain Tumors, Hardell, et al, May 4, 2000, www.medscape.com). Thei...Virus Level could Predict Cervical Cancer Risk
Cervical cancer is one of the most common cancers in women. If it ...measuring the levels of a virus linked to cervical cancer could help to identify women at risk from the disease long before it develops or is detected with co...Human Genome Project Achieves Technological Triumph
...nd determines our susceptibility to illnesses like cancer or diabetes. Mapping involves three separate steps: sequencing, assembling and annotating the genes. In the sequencing phase, researchers identified the approximate 3.5 billion chemical letters (A, C, G, T) that make up human DNA,the building block o...A controversial treatment for prostate cancer in which radioactive seeds are implanted in the pr...rs, but previous treatment guidelines for prostate cancer left the procedure out. "The weight of institutional experience at NCCN members allows us to expand ......scular mortality. However, height did not predict cancer mortality for either men or women. Height was inversely associated with serum cholesterol and family history of stroke in both men and women, the investigators noted. "In conclusion, we found that short stature was associated with most of the assess...Heraeus CO2 Incubator BBD 6220
...ries and for in vitro fertilization, as well as in cancer research or tissue engineering, the Heraeus CO2 incubator BBD 6220 provides the best contamination protection and optimum reproducibility of results....SenoScan TrueView Digital Mammography
...ved, and represents a breakthrough in early breast cancer detection. It is the first and only mammography system to offer 25-micron native diagnostic resolution - the highest available. SenoScan's larger field of view accommodates more patients. Its curved breast support is more comfortable and helps reduce......pproximately 500,000 people die each year of colon cancer - including 57,000 Americans. Despite diagnostic improvements (high contrast berium enema, colonoscopy, FOBT, flexible sigmoidoscopy, etc.) an increase in the success rate of curative treatment for colorectal carcinomas has not been achieved over the......th Hemoccult will reduce mortality from colorectal cancer by 20 to 40 percent....Digital vs. Analog Mammography
...e, multicenter trial to compare the two for breast cancer detection. The Digital Mammographic Imaging Screening Trial (DMIST) will involve 49,500 women in the United and Canada and cost $26.3 million. It is designed to test what smaller, earlier trials have suggested: that digital mammography may provide be...PSA TestingHow Much is Too Much?
...been widely used as the gold standard for prostate cancer screening. In one of the most dramatic reversals i...er a man should even use the PSA test for prostate cancer screening any more, Stamey said. The researchers opinion carries great influence, since it was Stame...Genetic Analysis Systems Enter the Clinical Mainstream
...nal marketplace. The uses of these kits range from cancer detection and staging to human growth factor analysis to diabetes typing. Some of these kits have been approved for use in the U.S. and inevitably many more will become available in the future. PerkinElmer Life and Analytical Sciences, Inc., Boston, ...Testing for Human Papillomavirus
...and intermediate risk types detected in anogenital cancer biopsy specimens. Worldwide, HPV has been associa...y of any one HPV infection progressing to cervical cancer is quite small. Nevertheless, cervical cancer represents the second most common cancer in women, wi...Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
...0,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most seri...t comes the promise of similar solutions for other cancer patients....