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Calcitonin in Medical News

While Some New Agents Will Achieve Strong Sales, the Migraine Drug Market Will Decline $1.3 Billion by 2018 as Generic Erosion Takes Toll on Top-Selling Brands

... overall migraine market during the next decade and will exert increasing pressure on new products. However, the emergence of Merck's first-in-class calcitonin gene-related peptide receptor antagonist telcagepant as an alternative to triptan therapy will help counteract market losses -- according to the ...

Par Pharmaceutical Begins Shipment of Generic Miacalcin(R)

... nasal spray should be reserved for patients who refuse or cannot tolerate estrogens or in whom estrogens are contraindicated. Because calcitonin is a polypeptide, the possibility of a systemic allergic reaction exists. Please read full prescribing information available at ...

New Migraine Drug Shows Promise

... high blood pressure and certain migraine subtypes, according to a news release about the study. Telcagepant is from a different class, called calcitonin gene-related peptide (CGRP) antagonists. It's believed that brain concentrations of CGRP are elevated during a migraine. CGRP antagonists don't seem ...

Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best

... (Didronel), ibandronate (Boniva), pamidronate (Aredia), risedronate (Actonel) and zoledronic acid (Zometa). The report also looked at estrogen, calcitonin (a man-made hormone), calcium, vitamin D, testosterone, parathyroid hormone and selective estrogen receptor modulators (SERMs). Not enough ...
Calcitonin in Medical Technology

Emisphere Announces Recruitment of Novartis Phase III Study for Oral Osteoporosis Treatment

... to Explore the Effects of Eligen(R) Delivery Technology and Salmon calcitonin on Vertebral Fractures in Postmenopausal Women CEDAR KNOLLS, N.J., Aug. ... a multi-center Phase III study exploring the safety and efficacy of Salmon calcitonin and Emisphere's proprietary Eligen(R) Technology in the treatment of ...

Exelixis Reports Encouraging Phase 1 Data for XL184 at ASCO

... of 17) experiencing partial responses. With a single exception, all of the evaluated MTC patients had reductions in the MTC-associated plasma markers calcitonin and carcinoembryonic antigen. Most of the MTC patients in the trial had previously failed other treatments, including tyrosine kinase inhibitors with ...

Genta Clinical Programs Featured at American Society of Hematology Meeting

... cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). G4544 was developed to ...

Genta Completes Initial Clinical Dosing of G4544, a New Oral Drug for Bone Diseases

... with cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). G4544 was developed to ...

Emisphere Technologies, Inc. Announces 2007 Third Quarter Financial Results

... progression of the illness rather than treating symptoms -- Both products use Emisphere's eligen(R) delivery technology to provide salmon calcitonin for the first time as a convenient oral medication Emisphere has three products in Phase II: -- Development of recombinant human growth hormone ...

Genta Initiates First Clinical Trial with New Oral Drug (G4544) to Treat Bone Disease

... with cancer-related hypercalcemia who were resistant to hydration, randomized double-blind trials have been conducted with Ganite compared with calcitonin and with two bisphosphonates (etidronate [Didronel(R); Proctor and Gamble] and pamidronate [Aredia(R); Novartis, Inc.]). About G4544 G4544 was ...

Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results

... progression of the illness rather than treating symptoms -- Both products use Emisphere's eligen(R) delivery technology to provide salmon calcitonin for the first time as a convenient oral medication Emisphere has three products in Phase II: -- Development of recombinant human growth hormone ...

Merck's Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study

... from a Phase II study presented for the first time at the American Headache Society (AHS) annual meeting showed that MK-0974, an investigational oral calcitonin gene-related peptide (CGRP) receptor antagonist, significantly improved migraine pain relief two hours after dosing compared to placebo, and the ...
Calcitonin in Medical Products

Calcitonin IRMA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of ... in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by ... of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated ...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin Assay Immunoradiometric (IRMA) Assay

Description:... The Scantibodies calcitonin Immunoassay is a two-site immunoradiometric assay ... Two different goat polyclonal antibodies to human calcitonin have been purified by affinity chromatography to be specific for well-defined regions on the calcitonin molecule. For the quantitative determination ...
Company:Scantibodies Laboratory, Inc.

Calcitonin, Ultra-Sensitive RIA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of ... in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by ... of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated ...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin RIA Test

Description:... calcitonin is synthesized in the parafollicular C-cells of ... in secretory granules. The major action of calcitonin is to lower plasma calcium concentrations, by ... of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated ...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin ELISA

Description:... The calcitonin ELISA is intended for the quantitative determination of calcitonin in human ....
Company:MD Biosciences

Nichols Advantage® Calcitonin Assay

Description:... Fully automated Chemiluminescence assay for the measurement of calcitonin hormone in ....
Company:Nichols Institute Diagnostics

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Calcitonin in Medical Definition

Proteopathy

... β2-microglobulin Inclusion body myopathy/myositis Amyloid β peptide (Aβ) Cataracts Crystallins Medullary thyroid carcinoma calcitonin Cardiac atrial amyloidosis Atrial natriuretic factor Pituitary prolactinoma Prolactin Hereditary lattice corneal dystrophy ...
Calcitonin in Medical Dictionary

Calcitonin

... calcitonin is a hormone produced in the C cells of the ... . Its role in humans is unclear. In animals, calcitonin helps to regulate blood calcium by slowing ... amount of calcium released from the bones. calcitonin -human ...

D and C

... our free newsletter or manage your subscriptions Get our RSS news feed ... Vitamin D and certain hormone s (such as parathyroid hormone and calcitonin ) help control the total amount of calcium in the body. They also regulate the amount of calcium absorbed from food and the amount removed from ...

Estrogen

... is one of the more common treatment s for osteoporosis . It both prevents and treats bone loss and increases bone density in the hip and spine. calcitonin is another drug that is sometimes used to decrease bone loss. Estrogen receptor positive. Breast cancer cells that have a protein ...

Exercise

... of exercise and make sure you have enough calcium in your diet . Ask your doctor about hormone replacement therapy and medicines such as calcitonin and Fosamax. WHAT YOU SHOULD DO ... LEG LIFTS - An exercise designed to strengthen the quadriceps muscle s. The patient lies on their back ...

Growth hormone

... decreased, some unchanged, and some increased with age. Hormone s that are usually decreased include aldosterone , renin , estrogen (in women), calcitonin , prolactin (in women), and growth hormone . Other conditions that can cause high blood glucose levels include severe stress , heart ...

Hip fracture

... Fitness, Hip Fracture , Menopause and Peri menopause , Quitting Tobacco Use Related Drugs for Osteoporosis : Estrogen , testosterone , calcitonin , Bisphosphonates, Raloxifene, Parathyroid hormone , Estrogen and progestin ... Women have a quick decrease in estrogen with menopause . Men ...

Hormone replacement therapy

... of exercise and make sure you have enough calcium in your diet . Ask your doctor about hormone replacement therapy and medicines such as calcitonin and Fosamax. WHAT YOU SHOULD DO ... These can be quite severe and last from weeks to years. Severe night sweats in this group of people are ...

Long bones

... height of the pituitary giant, which is defined at various levels above 7 ft (213 cm), is caused by excessive growth of the long bones . calcitonin slows thinning of bone in the spine, hip ( pelvis ), and ends of the long bones (trabecular bone), although it does not appear to be as ...

Parathyroid glands

... glands are also more likely to develop pseudogout . Calcium is also key to growth and healthy bones. Calcium levels are regulated by calcitonin from the thyroid and by parathyroid hormone , which is produced by four pea-sized parathyroid glands located just behind the thyroid. ...

Renin

... decreased, some unchanged, and some increased with age. Hormone s that are usually decreased include aldosterone , renin , estrogen (in women), calcitonin , prolactin (in women), and growth hormone . They serve as the body's filters to clean the blood of waste products, excess water and salt. ...

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Calcitonin in Biological Technology

Unigene Restates Policy on Analyst Reports

... is targeting its initial efforts on developing calcitonin and PTH-based therapies. Fortical(r), Unigene's nasal calcitonin product for the treatment of ... to GlaxoSmithKline and worldwide rights for its calcitonin manufacturing technology to Novartis. Unigene's ...

Stonegate Report About Unigene Laboratories Inc.

... peptides. Its initial focus is on salmon calcitonin (sCT) and other peptides for the treatment of ... (NYSE: GSK ) and the worldwide rights for its calcitonin manufacturing technology to Novartis Pharma AG ... also initiated a Phase III trial evaluating oral calcitonin against osteoporosis, which utilizes UGNE's ...

Emisphere Announces Recruitment Phase III Study for Oral Osteoarthritis Treatment

... Study to Explore the Effects of Oral Calcitonin, a combination of Salmon calcitonin and Eligen Delivery Technology on Knee Osteoarthritis Treatment CEDAR ... study exploring the safety and efficacy of an oral formulation of salmon calcitonin using Emisphere's proprietary Eligen Technology to treat patients with ...

Emisphere Technologies, Inc. Announces 2008 First Quarter Financial Results

... has two Phase III product candidates based on the compound salmon calcitonin in collaboration with Novartis Pharma AG and its development partner, ... candidates use Emisphere's eligen(R) delivery technology to provide salmon calcitonin as a convenient oral medication. There will be over 5000 patients enrolled ...

Emisphere Technologies, Inc. Announces 2007 Fourth Quarter and Year End Financial Results

... has two Phase III product candidates based on the compound Salmon calcitonin in collaboration with Novartis Pharma AG and its development partner, ... candidates use Emisphere's eligen(R) delivery technology to provide Salmon calcitonin as a convenient oral medication. Emisphere has two product candidates in ...

U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis

... or http://www.biomerieux-industry.com (1) Muller B, Becker KL, Schachinger H, Rickenbacher, PR, Huber PR, Zimmerli W, Ritz R. calcitonin precursers are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-983. ...

Michael V. Novinski, Emisphere President/CEO Featured in the Wall Street Transcript

... Through this program, "by the middle of this year, more than 5,000 patients will be taking Emisphere's eligen(R) technology with Salmon calcitonin for the treatment of osteoarthritis and osteoporosis," explained Mr. Novinski. "That's very exciting." The entire Wall Street Transcript interview ...

The development of a calcitonin-gene related peptide (CGRP) receptor-binding assay using the LEADseeker Multimodality Imaging System

... (WGA) PS RPNQ0260 LEADseeker SPA Imaging Beads (2-[125I]iodohistidyl10) calcitonin gene- IM184 related peptide (CGRP)

Other material ...

Calcitonin in Biological Definition

Hormone

... angiotensin antidiuretic hormone (ADH, also vasopressin, arginine vasopressin, AVP) atrial-natriuretic peptide (ANP, also atriopeptin) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone (CRH) erythropoietin ( EPO ) follicle stimulating hormone (FSH) gastrin ...
Calcitonin in Biological Dictionary

Polypeptide

... 4.3 Pancreatic polypeptide -related peptides. 4.4 Opioid peptides. 4.5 calcitonin peptides ... A polypeptide is a single linear chain of amino acids. ... Amylin, or Islet Amyloid Polypeptide (IAPP), is a 37-residue ...
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