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BLAST in Medical News

Traumatic brain injury caused by exposure to explosive blast presents critical challenge

... for studying the cause and effects of explosive blast TBI. This special issue of Journal of ... overview of the field entitled "Explosive blast Neurotrauma" was prepared by a group of authors ... Violent Explosive Neurotrauma (PREVENT) blast research program, and colleagues from the ...

Scientists uncover indicator that warns leukemia is progressing to more dangerous form

... is moving from the chronic phase in CML to the blast crisis stage, then we can hopefully intervene ... stem cells that carry BCR-ABL to the blast crisis stage. This stage is characterized by the ... and stopping the conversion of chronic CML to blast crisis stage was the failure to understand what ...

Blast overpressure is generated from the firing of weapons and may cause brain injury

... occupational standards for the highest levels of blast exposure were valid enough to avoid brain ... "We examined the maximal peak level of the blast in the brain transmitted from the blast in the air, as well as, brain tissue changes that ...

Traumatic Brain Injuries Linked to Long-Term Health Issues for Iraq Vets

... from shrapnel or gunshots. We're all worried that blast neurotrauma hasn't really made it into the human ... "They focused on blast-induced neurotrauma, a blast injury that leaves the head without any external ... for Research on Returning War Veterans. "The blast is so close and so large, it seems to be shaking ...

The physics of explosives and blast helmets

... risks for people caught within the immediate blast radius of an explosion. These include severe ... (e.g., concussion), pulmonary trauma (e.g., blast lung), and abdominal trauma (e.g., organ perforation or hemorrhage) caused by high values of blast overpressure; penetrating trauma caused by high ...

Out of Iraq emerges hope for those with the severest of head injuries

... Surgeons in Orlando, Fla. Huang discussed blast injuries, a type of wound that has affected ... from motor vehicle accidents, but we don't see blast injuries, and so neurosurgeons haven't really had ... by soldiers in previous wars. The extent of the blast injuries was far worse than I ever would have ...

Photo: New Data Show Gleevec(R) Halts Progression to Advanced Stages of Life-Threatening Form of Leukemia in Sixth Year of Treatment

... phase to a rapidly fatal form called blast crisis(1). "If this survival trend continues, ... five years(2). Once patients reached the final blast crisis phase, survival was generally three to six ... for the treatment of patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in ...

Scientists discover new role for miRNA in leukemia

... chronic phase to a life-threatening phase, called blast crisis. Furthermore, they discovered an ... The study, using cells from CML patients in blast crisis, suggests that certain progenitor white ... called miR-328 binds with a protein that, in blast phase CML, prevents immature blood cells from ...

Easter Seals Launches Program for Veterans Returning from Iraq and Afghanistan with Traumatic Brain Injuries

... Traumatic Brain Injury (TBI), with 25 percent of blast survivors at risk of TBI. Government reports cite nearly 22,000 blast survivors, leaving 5,500 service members with the ... neurological disorders from the blast waves of IEDs and mortars, all without ...

ChemGenex's omacetaxine may provide first viable treatment option for highly resistant form of CML

... from 66 patients: 40 in chronic phase, 16 in accelerated phase and 10 in blast phase. Highlights of the data were: Chronic phase patients ... months MCyR rate of 6% with a median response duration 1.8 months blast phase patients CHR rate of 20% with a median duration 3.3 months ...

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BLAST in Medical Technology

Sunesis Pharmaceuticals Announces Presentation of Voreloxin Clinical Data in Patients with Acute Myeloid Leukemia at the 50th Annual Meeting of the American Society of Hematology

... An additional 5 patients had bone marrow blast reductions to less than 5 percent. The median ... Three additional patients with bone marrow blast reductions are undergoing second induction cycles ... by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and ...

Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease

... for the treatment of patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in ... in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. ... in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. ...

Exelixis Presents Clinical Data Supporting the Safety and Initial Clinical Activity of XL228 in Chronic and Acute Leukemia

... an F317L BCR-ABL mutation in lymphoid blast crisis experienced a marked decrease in peripheral blast counts on XL228 (7.2 mg/kg) and hydroxyurea which ... tumor lysis syndrome in a patient with lymphoid blast crisis receiving concurrent treatment with ...

For Iraq Veterans, Headaches Continue After Traumatic Brain Injury

... -- Many soldiers who experienced mild head trauma or a blast exposure while serving in Iraq or Afghanistan are returning to the United ... or Afghanistan in 2008. All had experienced a concussion, head injury or blast exposure while deployed. Nearly 98 percent of the soldiers reported ...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

... limited to 5 years. Gleevec is also indicated for patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in the chronic phase (CP) after ... 4 studies among adult patients, with newly diagnosed Ph+ CML, patients in blast crisis, accelerated phase, and in the chronic phase after failure of ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... limited to 5 years. Gleevec is also indicated for patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in the chronic phase (CP) after ... 4 studies among adult patients, with newly diagnosed Ph+ CML, patients in blast crisis, accelerated phase and in the chronic phase after failure of ...

Sunesis Pharmaceuticals Initiates Phase 2 Clinical Trial of Voreloxin (SNS-595) in Acute Myeloid Leukemia

... of 50 mg/m2 or greater on a weekly dose schedule achieved bone marrow blast reductions to less than five percent, and five of those 13 achieved either ... of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The American Cancer Society estimates that over ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... not be taken to make up for any missed dose. * Numbers indicate the range of percentages in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. (+) For more detailed study information, please see full Prescribing Information. Disclaimer ...

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

... as defined by the Revised European-American Lymphoma (REAL) criteria, acute myeloid leukemia (AML), chronic myeloid leukemia (CML) in blast crisis, or high grade myelodysplastic syndrome (MDS) with >10% bone marrow involvement. Potential risk for TLS was defined as diagnosis of ...

Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia To Be Presented at ASH

... About Acute Myeloid Leukemia AML is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 ...
BLAST in Medical Products

Plasma Blast Chest Freezer -50C

Description:... Plasma blast Chest Freezer -50C - 8098/8091 maintains a -50C (-58F) temperature to rapidly freeze single donor, apheresed, and fresh frozen plasma. Rapid freezing ...
Company:ThermoFisher Scientific

Plasma Blast Upright Freezer -50C

Description: It includes 99 single plasma units. Model 8001 (8003), includes 11 roll-out drawers containing removable wire ....
Company:ThermoFisher Scientific
BLAST in Medical Dictionary

Cml

... Leukoplakia Lewy body dementia ... Previously approved for the treatment of patients with chronic myeloid leukemia ( CML ) in blast crisis, accelerated phase, or in chronic phase after failure of interferon- alpha therapy. Dosage form: 100-mg hard gelatin capsule. They ...

Megaloblastic anemia

... , namely, megaloblastic anemia in which there is a paucity of red blood cells and those that are made are unusually large and immature (so-called blast cells). FOLIC ACID - A member of the B complex vitamin group; necessary for normal production of red blood cells; deficiency results in ...
BLAST in Biological News

Relationships in rank and file

... best and most frequently used algorithms such as blast (Basic Local Alignment Search Tool) have to make ... at all. After all, the researchers expect blast to compare a given sequence the letter code ... in just a few minutes. Search engines like blast evaluate the similarity between a pair of ...

Researchers to use K-State's BSL-3 Lab for $1 million study of fungus threatening wheat crops

... leading a group of researchers to study the wheat blast fungus, a pathogen that has become a serious ... want to be prepared," Valent said. The wheat blast fungus is a close relative of a devastating ... to find genome fragments specific to the wheat blast pathogen. Valent said this would help in the ...

Special issue of BMC Microbiology spotlights standardized language for describing microbes

... annotations are made and showcases a whole- genome annotation of the rice blast fungus Magnaporthe oryzae using the Gene Ontology terms. blast disease is one of the most destructive diseases of rice crop known ...

American Chemical Society's Weekly PressPac -- Sept. 12, 2007

... process, quickly and accurately identifying the chemical composition of blast residues from IEDs in the field. It consists of an instrument, about the ... mixture. In the study, researchers used it to identify major components of blast residues in less than 10 minutes. ARTICLE #1 FOR IMMEDIATE RELEASE ...

Brewing a blast-less fertilizer

... 80 percent AN keeps an explosion from burning all its fuel. This renders a blast far less violent. There are no commercially available options totally ... being used as an explosive, Taulbee points out, Coal ash wont stop the blast from initiating, but it will stop it from propagating. Whats more, he ...

Demonstration Features Commercial Technology for Combating Terrorism

... FPED VII will cover 20 equipment categories, including: automated entry control systems and equipment; armored and utility vehicles; biometrics; blast protection/mitigation systems; cargo inspection devices; chemical and biological detection, mitigation and protection equipment; communications ...

Demonstration Features Commercial Technology for Combating Terrorism

... FPED VII will cover 20 equipment categories, including: automated entry control systems and equipment; armored and utility vehicles; biometrics; blast protection/mitigation systems; cargo inspection devices; chemical and biological detection, mitigation and protection equipment; communications ...

Locking parasites in host cell could be new way to fight malaria

... a calcium regulated protease, left parasites trapped inside the host cell. By adding calpain-1 back into the cell, parasites were able to once again blast free. Curious to know if the distantly related parasite T. gondii might use the same process, Greenbaum worked with Roos, who has pioneered the ...

Demonstration Targets Terrorism

... The demonstration covers 20 equipment categories, including: automated entry control systems and equipment; armored and utility vehicles; biometrics; blast protection/mitigation systems; cargo inspection devices; chemical and biological detection, mitigation and protection equipment; communications ...

Rot's unique wood degrading machinery to be harnessed for better biofuels production

... enzymatic machinery for attacking plant material. Instead, the evidence suggests that it utilizes an arsenal of small oxidizing agents that blast through plant cell walls to depolymerize the cellulose. This biological process opens a door to more effective, less-energy intensive and more ...

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BLAST in Biological Technology

Cascades Technologies, Inc. Chosen to Deliver IT Support on a DoD Blast Injury Research Program

... variety of web-based services in support of DoD's blast Injury Research Program. Working closely with ... International Corporation (NYSE: SAI ) and the blast Injury Research Program Coordinating Office (PCO) ... for Prevention, Mitigation, and Treatment of blast Injuries), the purpose of the program is to ...

Gleevec Receives FDA Priority Review as First Therapy to Reduce Recurrence of Gastrointestinal Stromal Tumors After Surgery

... for the treatment of patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in ... in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. ... in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. + ...

New Online Tutorials for Sequence Similarity Search Tools BLAST and FASTA

... tutorials on sequence similarity search tools blast and FASTA enable researchers to quickly and ... used sequence similarity search resources: blast and FASTA . BLAST, from the National Center for ... main features of the FASTA and blast algorithms      how to ...

FDA Approves New SPRYCEL(R) (Dasatinib) Product Labeling for Patients with Chronic-Phase CML

... phase, 10% in accelerated phase, 15% in myeloid blast phase CML, and 8% in lymphoid blast phase CML or Ph+ ALL. The most frequently ... frequency in patients with myeloid or lymphoid blast phase CML and Ph+ ALL. Elevations in ...

Oxygen Biotherapeutics, Inc. Adds Oxycyte TBI Clinical Trial Sites in Israel

... participate in this study, especially as it relates to TBI as a result of blast injury," said Chris J. Stern, company chairman and CEO. "Unfortunately, they have had to deal with blast victims for some time, both military and civilian. They see this as ...

Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia

... Gleevec is also indicated for the treatment of patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in the chronic phase (CP) after ... range of percentages in 4 studies among adult patients with Ph+ CML in blast crisis, accelerated phase, and chronic phase. + For more detailed ...

Brewing a blast-less fertilizer

... 80 percent AN keeps an explosion from burning all its fuel. This renders a blast far less violent. There are no commercially available options totally ... being used as an explosive, Taulbee points out, Coal ash wont stop the blast from initiating, but it will stop it from propagating. Whats more, he ...

K-State's Subbaratnam Muthukrishnan and Barbara Valent Named Fellows of the American Association for the Advancement of Science

... the mechanisms of fungal pathogenesis. She pioneered and developed rice blast disease as an easily manipulated model system to understand how plants and ... including one with other scientists for a glue purified from the rice blast fungus. ...

Brewing a blast-less fertilizer

... 80 percent AN keeps an explosion from burning all its fuel. This renders a blast far less violent. There are no commercially available options totally ... being used as an explosive, Taulbee points out, Coal ash wont stop the blast from initiating, but it will stop it from propagating. Whats more, he ...

Sunesis Reports Financial Results for the Second Quarter 2009

... About Acute Myeloid Leukemia AML is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths ...
BLAST in Biological Products

Beacon Designer from PREMIER Biosoft International

Description:... molecular beacon, NASBA and FRET assays. Highly specific primers are designed by avoiding cross homologies found by automatically interpreting blast search results. Primer efficiency is enhanced by avoiding template secondary structures identified by connecting to the Mfold server. Beacon Designer ...
Company:PREMIER Biosoft International
BLAST in Biological Definition

BLAST

... For other uses, see blast (disambiguation) . In bioinformatics , B asic L ocal A lignment S earch T ool, or blast , is an algorithm for comparing biological ... . Given a library or database of sequences, a blast search enables a researcher to look for ...

Bioinformatics

... the fate of cell clusters during morphogenesis . Software tools The computational biology tool best-known among biologists is probably blast , an algorithm for searching large sequence (protein, DNA) databases. NCBI provides a popular implementation that searches their massive sequence ...

Bioinformatics

... the fate of cell clusters during morphogenesis . Software tools The computational biology tool best-known among biologists is probably blast , an algorithm for searching large sequence (protein, DNA) databases. NCBI provides a popular implementation that searches their massive sequence ...
BLAST in Biological Dictionary

X chromosome

... . ... Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's ... Chromosome X . Overview. Mapping Data. blast Search. Team. Website ... The human X chromosome has a unique biology that was shaped ... X Chromosome ... One X chromosome gives ...

Sequence similarity

... evolutionary trees. ... 63% of the families shared significant sequence similarity . ... Sequence similarity search page at EBI. NCBI: blast notebook. BLITZ ULTRA Fast Search at EMBL ... PimaII find sequence similarity using dynamic programming ... Sequence Similarity - ...

Sequence

... physical optimization of leakage power,MTCMOS power gating & multi-Vt,active power, ... Query sequence (s) to be used for a blast search should be pasted in the 'Search' text area. ... These NCBI sequence identifiers have a very specific syntax as ... Navigation through ...

Saccharomyces cerevisiae

... Cerevisiae at NexTag.com. Shop for Bargain Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. Retrieve Align blast Clear. Species Saccharomyces cerevisiae (Baker's yeast) ... Saccaromyces cerevisiae " Saccharomyces capensis " Saccharomyces italicus " ... ...

Prophage

... toxin ... Prophage Finder initially uses BLASTX to compare input DNA sequences to a ... This Perl program predicts prophage by clustering blast hits based on the number ... prophage ... Prophage - Wikipedia, the free encyclopedia ... prophage definition ... Britannica online ...

Intein

... causes, diseases, symptoms, treatments, and other medical and health issues. ... Intein : The internal fragments of ... An intein -specific blast server is now available to assist in identifying new inteins. ... first crystal structure of an intein precursor shed light onto the ... We ...

Heterogeneous nuclear RNA

... ... Kinetics of hybridization to human DNA of heterogeneous nuclear RNA isolated from normal human lymphoblasts and acute leukemia blast cells. - G Torelli, F Narni, G ... ...
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(Date:7/31/2014)... 31, 2014 Leelanau Peninsula’s newest winery, ... 2014 at 7788 East Horn Road in Lake Leelanau. Joining ... , Aurora Cellars is the 25th winery along the trail. ... popular wine tour events, making its trail event debut during ... , Owners David and Faye Mathia opened the boutique ...
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