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Bacteriophages in Medical News

Engineered Viruses Could Battle Superbugs

... Boston University scientists engineered existing bacteriophages (viruses that infect bacteria) to attack the SOS ... with bacteria and treated with engineered bacteriophages and antibiotics was 80 percent, compared with 50 percent for mice treated with natural bacteriophages and antibiotics, 20 percent for mice treated with ...

Eleven Veterinary Students Win Top Awards at Morris Animal Foundation's Annual Research Competition

... for Companion Animals, $5,000 each ( tie ) Mia Lieberman, University of California-Davis D07EQ-622 : "Isolation and Purification of Lytic bacteriophages Against Streptococcus equi subspecies equi " Stephanie Montgomery, North Carolina State University D07CA-627 : "Development of a ...

New viruses to treat bacterial diseases -- 'My enemies' enemy is my friend'

... Europe and the USA. The main human clinical reports have come from Eastern Europe, particularly the Tbilisi Bacteriophage Institute in Georgia where bacteriophages are used for successful treatment of infections such as diabetic ulcers and wounds. More studies are planned along western clinical trial lines with ...

FDA Extends GRAS Approval Listex to All Food Products

... specific in regard to the bacteria they recognize. The LISTEX(TM) bacteriophages target only Listeria bacteria (leaving desirable bacteria in place), and ... who are insisting on 'green' solutions, rather than chemicals. Natural bacteriophages prove to be a unique solution, where increased safety does not come at the ...

Virus-mix-spray destroys bacteria on Prepackaged meats

... in another 6-month’s time. Similar to E.coli, Listeria cannot be washed away. Only cooking of the food or application of these viruses or bacteriophages kills Listeria. Listeria causes serious illness in nearly 2,500 people and death in around 500 people each year. In spite of the FDA’s assertion ...
Bacteriophages in Biological News

Pitt-led researchers create quick, simple fluorescent detector for TB

... isolated and treated." The group constructed bacteriophages specific to TB that have a green fluorescence protein (GFP) implanted in their genome. bacteriophages spread by injecting their DNA into bacterial ... with antibiotics at the same time the bacteriophages were introduced; the TB strains that were ...

NYU scientists discover dangerous new method for bacterial toxin transfer

... of the more notorious S. aureus toxins. Since bacteriophages are extremely common among bacteriaa drop of ... from an S. aureus strain to L. monocytogenes via bacteriophages in the labusing a strain in which the gene for ... resistance with a new strategy that uses bacteriophages to attack the infection-causing microbes. When ...

Einstein and Pitt researchers develop new TB test that will dramatically cut diagnosis time

... with a green fluorescence protein (GFP) implanted in their genome. bacteriophages spread by injecting their DNA into bacterial cells. In this case, the GFP ... Researchers treated M. tuberculosis with antibiotics at the same time the bacteriophages were introduced; the TB strains that were sensitive to antibiotics died, ...

Viruses evolve to play by host rules, according to University of Pennsylvania researchers

... the tendency to preferentially encode a protein with a particular spelling. Researchers analyzed patterns of codon usage across 74 bacteriophages using the concept of a "genome landscape," a method of visualizing long-range patterns in a genome sequence. Their findings extend the ...

Engineers improve plastic's potential for use in implants by linking it to biological material

... plastic-preferring peptide, Sanghvi and Miller added a solution containing bacteriophages that displayed different peptides to a container with polypyrrole stuck on its inner surface. The bacteriophages that didn't wash away when exposed to conditions that hinder attachment ...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

... class II HLA and transfer them into recipient cells, along with the cDNA library. With her new technique, Herlyn expresses the cDNA library in bacteriophages that are incubated with B cells from the same patient from whom the T cells were derived. Because B cells are antigen-presenting cells, once they ...

Where Bacteria Get Their Genes

... the bacterial genome can be incorporated into the newly made phages. They inject their newly modified genetic load into other bacteria. This way, bacteriophages act as shuttles, taking up DNA from one bacterium and dumping it into another. Bacteria can also make contact by tiny connection tubes through which ...

Where bacteria get their genes

... the bacterial genome can be incorporated into the newly made phages. They inject their newly modified genetic load into other bacteria. This way, bacteriophages act as shuttles, taking up DNA from one bacterium and dumping it into another. Bacteria can also make contact by tiny connection tubes through which ...
Bacteriophages in Biological Technology

MIT, BU team combats antibiotic resistance with engineered viruses

... of biomedical engineering at BU, took a new approach: engineering existing bacteriophages (viruses that infect bacteria) to attack specific targets. "It's much ... survival rate, compared with 50 percent for mice treated with natural bacteriophages and antibiotics, 20 percent for mice treated only with antibiotics, and 10 ...
Bacteriophages in Biological Definition

Phage

... by integrating multiple genes from a gene bank into phages. Model bacteriophages Following is a list of bacteriophages that are extensively studied: λ phage - Lysogen T4 phage ...

Virus classification

... - dsDNA viruses (double stranded DNA) Order Caudovirales (tailed bacteriophages ). Family Myoviridae - e.g. Enterobacteria phage T4 Family ... Group II - ssDNA viruses (single stranded DNA) Unassigned bacteriophages Family Inoviridae Family Microviridae Unassigned ...

Virus

... carrier. Inside the organism, the virus can enter a cell in various ways. bacteriophages —bacterial viruses—attach to the cell wall surface in specific ... cell at these exit sites, referred to as exocytosis. On the other hand, bacteriophages must break open, or lyse , the cell to exit. To do this, the phages have ...

Hershey-Chase experiment

... and 32 P T2 contained the 32 P isotope, while the 35 S strains did not, providing more evidence that DNA was the genetic information that bacteriophages inject into bacteria , not protein . ...

Immune system

... to the blood. Bacteria and monocellular organisms have an "immune system" (under the broader of the two definitions above) designed to combat bacteriophages (viruses that infect bacteria). They do this by simultaneously expressing restriction enzymes that cut DNA at certain sequences, and enzymes ...

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Bacteriophages in Biological Dictionary

Phage

... one of a number of viruses that infect bacteria. bacteriophages are among the most common organisms on Earth. The ... . Phage therapy is the therapeutic use of bacteriophages to treat pathogenic bacterial infections. ... into bacterial cell An electron micrograph of bacteriophages attached to a bacterial cell P22 is a ...

Bacteriophages

... one of a number of viruses that infect bacteria. bacteriophages are among the most common organisms on Earth. ...rm,... Phage therapy is the therapeutic use of bacteriophages to treat pathogenic bacterial infections. ... the lytic life cycle of a bacteriophage . ... bacteriophages can have a protein "tail" attached to the ... ...

Bacteriophage

... A bacteriophage is any one of a number of viruses that infect bacteria. bacteriophages are among the most common organisms on Earth. The term is commonly used in its shortened ... any of a group of viruses that infect bacteria. bacteriophages were discovered independently by Frederick W. Twort in Great Britain ...

Expression Vector

... is a DNA molecule used as a vehicle to transfer foreign genetic material into another cell. The four major types of vectors are plasmids, bacteriophages and other viruses, cosmids, and artificial chromosomes. Common to all ... expression vector ( ik′spreshən ′vektər ) ( cell and ...

Coat protein

... composed of protein . ... ments for protein incorporation into the viral coat . ... The coat proteins of the single-stranded RNA bacteriophages are translational ... Wild-type PP7 operator RNA binds PP7 coat protein with Kd = 1 nM. ... Conditions for the purification of coat ...

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