Alseres Pharmaceuticals, Inc.'s Chairman, Peter Savas, Reviews Company's Progress in its Annual Letter to Stockholders
... the action of Rho, a key enzyme that prevents
axon (nerve) regeneration. Rho potentially plays an ... pro-regenerative pathways that stimulate
axon regeneration and for approaches to deactivate anti-regenerative pathways that inhibit
axon regeneration. We believe that our Rho ...
Scientists shed light on long-distance signaling in developing neurons
... very tips of the developing neuron's long, skinny
axon affect gene transcription back in the cell's ... recent years, scientists discovered that as the
axon reaches its target -- which may be many ... get passed from the growth cone at the tip of the
axon back to the cell's "command center," the nucleus? ...
Eye Scan May Help Diagnose, Treat MS
...
In fact, according to the study authors,
axon degeneration resulting from "demyelination" and ... "This allows you to measure the thickness of the
axon itself," O'Looney explained.
The cost of the ... forward in developing new drugs to protect the
axon from damage, we need a way to measure that. And ...
Brain cells work differently than previously thought
... then relays the processed information along an
axon to a terminal that links to another cells ... with hearing that contained a brain cell with an
axon connecting to the cortex. Using nicotine, they stimulated the
axon to determine how it would affect a signal the ...
Lab-grown nerves promote nerve regeneration after injury
... Smith and colleagues have successfully grown, transplanted, and integrated
axon bundles that act as 'jumper cables' to the host tissue in order to bridge ... a cylinder that looks similar to the longitudinal arrangement of the nerve
axon bundles before it was damaged. The long bundles of axons span two ...
Novel Photoconductive Cellular Depolarization Technology Reveals Insight Into Neuronal Growth, Guidance, and Regeneration
... recovery. Given this, researchers have sought to better understand how
axon guidance is mediated in order to potentially aid in recovery following ... These observations suggest a signaling pathway for activity-dependant
axon guidance in which growth guidance both spatial and temporal is mediated by ...
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axon in Medical Technology
Alseres Pharmaceuticals Completes Enrollment in First Stage of the Altropane(R) POET-2 Phase III Program
... and Cethrin, the prospects of the Company's CNS and regenerative therapeutics programs, the Company's strategies to develop and commercialize
axon regeneration technologies and the breadth of the Company's technologies and intellectual property portfolio. Forward-looking statements can be ...
Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine
... improved therapies for prostate cancer are urgently needed.
Contact: Anders Hedegaard, President & CEO - +45-23-20-30-64;
Vicki Martin,
axon Communications - +44-208-439-9407 / vmartin@axon-com.com .
...
Genetic Engineering & Biotechnology News Reports on the Growing Role of Ion-Channel Studies in Global Biotech R&D
... chronic atrial fibrillation.
Also discussed in the GEN article is ion-channel work at Organon
Laboratories, ChanTest, Molecular Devices and
axon Instruments (both now
part of MDS Analytical Technologies), Sophion Bioscience, Nanion
Technologies, and Flyion.
For a copy of the June 1 issue of ...
Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury
... and Cethrin, the prospects of the Company's CNS and regenerative
therapeutics programs, the Company's strategies to develop and
commercialize
axon regeneration technologies and the breadth of the
Company's technologies and intellectual property portfolio. Forward-looking
statements can be ...
Alseres Pharmaceuticals Enters Agreement to Amend Cethrin(R) License to Lower Milestone Payments and Royalty Rates
... and Cethrin, the prospects of the Company's CNS and regenerative
therapeutics programs, the Company's strategies to develop and
commercialize
axon regeneration technologies and the breadth of the
Company's technologies and intellectual property portfolio. Forward-looking
statements can be ...
Alseres Pharmaceuticals Expands Sites for the First Stage of the ALTROPANE(R) Phase III Clinical Trial Program
... and CETHRIN, the prospects
of the Company's CNS and regenerative therapeutics program, the Company's
strategies to develop and commercialize
axon regeneration technologies and
the breadth of the Company's technologies and intellectual property
portfolio. Forward-looking statements can be ...
axon in Medical Products
EpochXP Neurological Workstations
Description:... care unit to accurately access your patients neurological status.
Designed with over 15 years experience, and a long history of achievements,
axon Systems EpochXP neurological monitoring systems have a proven record of accurate and reliable performance. And now, with the built-in transcranial ...
Company:Axon Systems
EpochXP Neurological Workstation
Description:... care unit to accurately access your patients neurological status.
Designed with over 15 years experience, and a long history of achievements,
axon Systems EpochXP neurological monitoring systems have a proven record of accurate and reliable performance. And now, with the built-in transcranial ...
Company:Axon Systems
axon in Medical Definition
Depolarization-induced suppression of inhibition
... I, Sperlagh B, Sik A, Kafalvi A, Vizi ES, Mackie K, Freund TF. (1999) Presynaptically located CB1 cannabinoid receptors regulate GABA release from
axon terminals of specific hippocampal interneurons. J Neurosci. Jun 1;19(11):4544-58.
Kreitzer AC, Regehr WG. (2001a). Retrograde inhibition of ...
axon in Medical Dictionary
Nerve
... (destruction of parts of the myelin sheath covering the nerve ) and
axon degeneration (destruction of the
axon portion of the nerve cell ), ... Nerve : A bundle of fiber s that ...
Cone
... has since gone away. Now, his head looks a bit pointed in that same area. Should I worry about these things? Answer: Absolutely, you should worry.
axon guidance molecules are molecules outside the growth cone that assist in selection of the correct pathway and target by changing growth direction. ...
Necrotizing vasculitis
... Amyloidosis (sural nerve biopsy is most often used) Sarcoidosis Leprosy Metabolic neuropathies Inflammation of the nerve Loss of
axon tissue Demyelination ... Disease s which cause retina l vasculitis include Behcet's disease , systemic lupus erythematosus , antiphospho ...
Neuron
... and weak. A person's intellect, however, is unaffected. Neuron s vary greatly but share three major features. Each has a centre (nucleus), an
axon which transmits nerve impulses electrochemically to other cells and branches (dendrites) which receive them. neuron A type of cell that ...
Vasculitis
... Amyloidosis (sural nerve biopsy is most often used) Sarcoidosis Leprosy Metabolic neuropathies Inflammation of the nerve Loss of
axon tissue Demyelination ... Polyarteritis nodosa is a rare, but potentially life threatening, inflammation of the blood vessels ( vasculitis ...
axon in Biological News
What makes an axon an axon?
... Inside every
axon is a dendrite waiting to get out. Hedstrom et al. ... online Nov. 10.
At the junction between the
axon and the cell body is the
axon initial segment (AIS), which sparks action ...
Rare genetic disorder gives clues to autism, epilepsy, mental retardation
... transmit signals). Normal neurons grow just one
axon and multiple dendrites (short projections that ... the researchers were able to limit multiple
axon formation by using the cancer drug rapamycin to ... increased SAD-A is associated with increased
axon growth, the researchers also speculate that the ...
A second career for a growth factor receptor: keeping nerve axons on target
... neurons live or die, leads a double life as an
axon guidance protein.
"Historically, we thought ... that mediate cell survival and those controlling
axon guidance were part of two separate processes," ... was a well-characterized sender and receiver of
axon guidance signals, but it lacked appendages ...
NJIT biomedical engineer receives NSF Career Development Award
... to support and expand his research into rapid
axon stretch growth, a technique for regenerating ... PA, recreated in the laboratory a natural form of
axon growth that occurs through stretching as an ... device that uses live imaging techniques to study
axon growth.
Pfister received his PhD in materials ...
Identification of a key molecular pathway required for brain neural circuit formation
... to severe abnormalities of the nervous system. "Knowing the effectors of
axon guidance molecules such as Shh", adds Dr. Charron, "helps us to understand ... This invention is expected to speed up the discovery of drugs that control
axon pathfinding.
"Dr. Charron is one of the country's leading newly arrived ...
New findings in taste and smell
... organ
Emx2 stimulates odorant receptor gene expression and controls OSN
axon growth
Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons mediate
axon targeting and glomerular formation
Investigations of olfactory receptor ...
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axon in Biological Technology
Alseres Pharmaceuticals, Inc. Reports 2007 Financial Results and Provides Company Highlights
... Inosine is a nerve regenerative factor that has been shown to promote
axon outgrowth in neurons and has potential to be used to treat CNS ... programs, the Company's strategies to develop and
commercialize
axon regeneration technologies and the breadth of the
Company's technologies ...
Alseres Pharmaceuticals, Inc. Complies with NASDAQ Rule Regarding Recently Filed 10-K
... and Cethrin, the prospects of the Company's CNS and regenerative therapeutics programs, the Company's strategies to develop and commercialize
axon regeneration technologies and the breadth of the Company's technologies and intellectual property portfolio. Forward-looking statements can be ...
Alseres Pharmaceuticals, Inc. Announces $1 Million Financing
... and Cethrin, the prospects of the Company's CNS and regenerative therapeutics programs, the Company's strategies to develop and commercialize
axon regeneration technologies and the breadth of the Company's technologies and intellectual property portfolio. Forward-looking statements can be ...
Alseres Pharmaceuticals, Inc. Reports Third Quarter 2008 Operational and Financial Results
... and Cethrin, the
prospects of the Company's CNS and regenerative therapeutics programs, the
Company's strategies to develop and commercialize
axon regeneration
technologies and the breadth of the Company's technologies and intellectual
property portfolio. Forward-looking statements can be ...
Alseres Pharmaceuticals, Inc. Raises $5 Million
... and Cethrin, the prospects of the Company's CNS and regenerative
therapeutics programs, the Company's strategies to develop and
commercialize
axon regeneration technologies and the breadth of the
Company's technologies and intellectual property portfolio. Forward-looking
statements can be ...
Alseres Pharmaceuticals Presents Inosine and Dopamine Transporter (DAT) Blocker Preclinical Data at the American Society for Experimental NeuroTherapeutics (ASENT) Conference
... infused intravenously was measurably able to cross the
blood- brain barrier. Inosine is a nerve regenerative factor that has been
shown to promote
axon outgrowth in neurons and has potential to be used to
treat CNS disorders such as stroke, spinal cord injury and traumatic brain
injury.
"The ...
axon in Biological Definition
Axon
... An
axon , or " nerve fiber ," is a long slender ... .
The axons of some neurons branch to form
axon collaterals , along which the bifurcated impulse ... Hodgkin and Andrew Huxley also employed the squid
axon (1939) and by 1952 they had obtained a full ...
Neuron
... cell between the dendrites and the axon.
The
axon , a much finer, cable-like projection which may ... neuron. Each neuron has only one axon, but this
axon may undergo extensive branching and thereby ... information receiving network for the neuron.
axon and dendrites alike are typically only about a ...
Dendrite
... potentials do propagate back into the dendrites once initiated in the
axon in most neurons. This backpropagating action potential is mediated by the ... comes from the Greek word dendron , meaning "tree".
Compare :
axon
See also : dendritic spine
...
Electrophysiology
... Disadvantages: Impossible to record from single channels.
4.
axon recording.
Advantages: Chemistry of cell is unchanged,
axon pulses are discriminated from the less frequent retrograde cell action ...
Andrew Huxley
... of a technique of electrophysiology known as the "voltage clamp". The second critical element of their research was the so-called giant
axon of Atlantic squid ( Loligo pealei ), which enabled them to record ionic currents as they would not have been able to do in almost any other neuron ...
Cell growth
... mechanisms of mammalian cell size control are currently being investigated.
The size of post-mitotic neurons depends on the size of the cell body,
axon and dendrites. In vertebrates , neuron size is often a reflection of the number of synaptic contacts onto the neuron or from a neuron onto other ...
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axon in Biological Dictionary
Axon
... An
axon or nerve fiber is a long, slender projection of ... trucking company management software from
axon includes dispatch, A/R, A/P, payroll, work ... Industry News. What is PMCm? News Briefs ...
axon will exhibit at this year's BIRTV, booth number ...
Nerve impulse
... nerve impulse is able to skip across the unmyelinated regions of the
axon at ... ... electrical impulse propagates down the fiber-like ... nerve cell (the axon) ... Transmission of a nerve impulse along an
axon ... ...
Myelin sheath
... material that forms a layer, the myelin sheath , usually around only the
axon of a neuron. It is essential for the proper functioning of the nervous ... envelope of myelin that surrounds the core of a nerve fiber or
axon and facilitates the transmission of nerve impulses myelin also ...
Myelin
... material that forms a layer, the myelin sheath, usually around only the
axon of a neuron. It is essential for the proper functioning of the nervous ... envelope of myelin that surrounds the core of a nerve fiber or
axon and facilitates the transmission of nerve impulses The Myelin Repair ...
Motor neuron
... ... ( The diagram represents a motor neuron with most of its
axon omitted. ... Most motor neurons are stimulated by interneurons, ... in ALS. 1. Are sensory nerves ... The upper motor neuron
axon extends all the way from the brain down to the ... The axons of these ...
Cell body
... the cell body . ... Neuron: cell composed of a cell body , an
axon and dendrites, forming a functional unit ... Cell body : part of the nerve cell between the
axon and the dendrite. ... In this study we address the role of the cell ...
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