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Ascites in Medical News

Study unmasks how ovarian tumors evade immune system

... of the study, researchers collected lipid-filled ascites from 25 women with ovarian cancer and then ... the first to demonstrate the clinical effect of ascites on human NKT cells and describe the regulatory ... in humans about the immune-suppressing effects of ascites on NKT cells, which are also abundant in cancers ...

Also in the Nov. 11 JNCI

... or LPA3. Previous studies indicated that LPA is present at high levels in ascites fluid in ovarian cancer patients, and the receptors are expressed in ... LPA receptors gave rise to larger tumors and produced a larger volume of ascites than cells that did not express the receptors. Additionally, the LPA ...

High circulating D-dimers are associated with presence of ascites

... with ascites, led Agarwal et al. to suggest the major role of ascites in the pathogenesis of the hyperfibrinolytic state associated with liver ... The finding of high plasma D-dimer levels in cirrhotic patients without ascites may represent a marker of HCC. ...

Liver transplant offers survival benefits for patients of all sizes

... in the following way: underweight (BMI 40). The researchers compared outcomes for patients within these groups after adjusting for age, gender, race, ascites status, diagnosis and Model of End-Stage Liver Disease (MELD) score. Our study demonstrates a clear survival benefit for liver transplant ...

Hepatitis C treatment reduces the virus but serious liver problems may progress

... gradual scarring of the liver that puts patients at risk for progressive liver disease. The outcomes assessed in HALT-C were death, liver cancer, ascites (excess fluid in the abdomen), or encephalopathy (brain and nervous system damage), and for those who did not have cirrhosis initially, the ...

Preventing variceal bleeding

... and stomach to bypass the blockage. The se varices become fragile and can bleed easily, causing frightening symptoms like vomiting blood, as well as ascites and encephalopathy. Two ways to prevent variceal bleeding are beta blockers and endoscopic variceal ligation, however it is unclear which is better ...

Stem cells help in the understanding of drug-resistant, recurrent tumors

... stem cells found with other tumors. They then observed a small percentage of stem-like cells in human ovarian cancer lines and in cells taken from ascites fluid that had accumulated within the abdomen of several ovarian cancer patients. When mouse ovarian tumor stem-like cells were injected under the ...
Ascites in Medical Technology

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

... of first clinical event, defined as liver decompensation (variceal bleeding, Child-Pugh class C, grade 2 or higher hepatic encephalopathy, ascites requiring therapeutic paracentesis and/or additional therapy), development of hepatocellular carcinoma (HCC), liver transplantation or death. All ...

Kosan Initiates Phase 2 Trial of Alvespimycin, Second-Generation Hsp90 Inhibitor, in HER2-Positive Metastatic Breast Cancer

... Of the 3 patients with ovarian cancer, 1 patient (13 prior regimens) who was on study for more than 16 months had a near complete resolution of ascites and left pleural effusion, and an 83% decrease in CA125. Toxicities in this Phase 1 trial were mainly Grade 1 and 2 (diarrhea, fatigue, headache, ...

Kosan's Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial

... cancer, -- 1 patient (13 prior regimens) who was on study for more than 19 months with evaluable disease had a near complete resolution of ascites and left pleural effusion at the end of cycle 2, and an 83% decrease in CA125. Toxicities were mainly Grade 1 and 2 (diarrhea, fatigue, ...

Kosan Presents Promising Phase 1 Data on Second-Generation Hsp90 Inhibitor, Alvespimycin, Showing Antitumor Activity in Refractory Breast and Ovarian Cancers at ASCO

... with ovarian cancer, -- 1 patient (13 prior regimens) who was on study for more than 16 months had a near complete resolution of ascites and left pleural effusion, and an 83% decrease in CA125. Toxicities were mainly Grade 1 and 2 (diarrhea, fatigue, headache, arthralgia, ...
Ascites in Medical Dictionary

Ascites

... ascites : Abnormal buildup of fluid in the abdomen . ascites can occur as a result of a number of conditions, ... All of MedicineNet For: search help ... ascites is an abnormal accumulation of fluid in the ...

Endocrine

... throughout your body. Endocrine and renal ascites are rare disorders. Endocrine ascites , sometimes a symptom of an endocrine system ... women who are taking fertility drugs. Renal ascites develops when blood levels of albumin dip ...

Albumin

... the ankles ( pedal edema ), lungs ( pulmonary edema ), or abdomen ( ascites ). Albumin in urine ( Albumin uria): Hot Blanket Pack and other ... par albumin ; ... Failure of liver function results in ascites (fluid accumulation in the abdominal cavity ), increased albumin and ...

Cirrhosis

... decrease in liver function, excessive fluid in the abdomen ( ascites ), ... Cirrhosis What is cirrhosis ? Cirrhosis is a liver disease ... ... Cirrhosis , which is responsible for 80% of all instances of ascites in the United States, triggers a series of disease -producing changes ...

Cyst

... sinus . Cirrhosis , which is responsible for 80% of all instances of ascites in the United States, triggers a series of disease -producing changes ... the kidney 's ability to excrete sodium in the urine . Pancreatic ascites develops when a cyst that ... Congestive heart failure A buildup ...

Hepatic encephalopathy

... tasks. Examination may reveal hepatic encephalopathy , jaundice , ascites , and other signs of liver failure along with the decrease in kidney ... from scarring ( cirrhosis ) of the liver , often contributing to ascites , hepatic encephalopathy , and esophageal variceal bleeding . ...

Liver disease

... and liver disease s , but most prominenetly for skin complaints. ascites : Abnormal buildup of fluid in the abdomen . ascites can occur as a result of a number of conditions, including severe liver ...

Liver

... by end-stage cirrhosis manifested by esophageal variceal hemorrhage , ascites , and/or hepatic encephalopathy . LIVER CONGESTION"Fomentation over ... High blood lactic acid ... Failure of liver function results in ascites (fluid accumulation in the abdominal cavity ), increased albumin and ...

Aminoaciduria

... hepatomegaly (enlarged liver ), hypoglycemia ( low blood sugar ), aminoaciduria ( amino acids are present in the urine ), cirrhosis , ascites (fluid collected within the abdomen ), cataracts and mental retardation . ...

Anatomy

... nutrition from the mother during pregnancy is important in the development of the teeth . - Anatomy of a Normal Placenta - Antibodies - ascites with Ovarian Cancer , CT Scan - Bleeding Between Periods - Candida , Flourescent Stain - Causes of Painful Intercourse - Causes of Vaginal ...

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Ascites in Biological News

Mass. General study finds potential ovarian cancer stem cells

... stem cells found with other tumors. They then observed a small percentage of stem-like cells in human ovarian cancer lines and in cells taken from ascites fluid that had accumulated within the abdomen of several ovarian cancer patients. When mouse ovarian tumor stem-like cells were injected under the ...
Ascites in Biological Technology

China Biologic Products Announces SFDA Approval for the Production and Sale of Human Albumin 12.5g/vial (25%, 50 ml)

... and delivers the highest dosage of the Human Albumin family products in Mainland China, and has a better effect on the clinical application for ascites due to liver cirrhosis, external injuries, hydrocephalus due to cerebral hemorrhage, serious hypoproteinemia, and other major diseases. With this ...

Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies

... products, the IsoDetect kit requires only a simple dilution of ascites or culture media with the provided phosphate buffered saline ... isotypes of mouse monoclonal antibodies from tissue culture and ascites samples. The method uses a colloidal-gold conjugate technique to achieve ...

The Bio-Rad Silver Stain, Rev E

... Acad Sci USA 82, 87958799 (1985) 21. Gemski MJ et al., Single step purification of monoclonal antibody from murine ascites and tissue culture fluids by anion exchange high performance liquid chromatography, Biotechniques, 3, 378-384 (1985) 22. Goldman ...
Ascites in Biological Products

Hybridoma Development from QED Bioscience Inc.

Description:... 1. Antibody is produced either in ascites (5 mice per clone) or in vitro (150 ml per ... Completion Time: 5-6 months ($8,925.00) GMP ascites Production QED offers complete programs for ascites production, from small R&D scale to pilot lot ...
Company:QED Bioscience Inc.

Mouse Anti-Mouse Ly 6C.2(Ly 28.2) Monoclonal Antibody, Unconjugated, Clone 5075-3.6 from CEDARLANE Laboratories Limited

Description:... Anti-Mouse Ly 6C.2 , ascites (Clone 5075-3.6) (mouse ...
Company:CEDARLANE Laboratories Limited

Mouse Anti-NY-ESO-1 Monoclonal Antibody, Unconjugated, Clone E978 from Upstate

Description:... Anti-NY-ESO-1, clone E978 GenBank Accession Number : NM_001327 Immunogen : NY-ESO-1 full-length recombinant protein Formulation: mouse ascites with 0.05% sodium azide Quality Assurance: routinely evaluated by immunoblot on RIPA lysates from SKMEL-19 cells Recognizes ...
Company:Upstate

Mouse Anti-Mouse Qa.m7 Monoclonal Antibody, Unconjugated, Clone 5035-50.1 from CEDARLANE Laboratories Limited

Description:... Anti-Mouse Qa.m7, ascites (Clone 5035-50.1) (mouse ...
Company:CEDARLANE Laboratories Limited

Mouse Anti-Mouse Qa.m8 Monoclonal Antibody, Unconjugated, Clone 5035-24.1 from CEDARLANE Laboratories Limited

Description:... Anti-Mouse Qa.m8, ascites (Clone 5035-24.1) (mouse ...
Company:CEDARLANE Laboratories Limited

REC. PROTEIN G - SEPHAROSE from Invitrogen

Description:... G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to capture immune complexes generated in ...
Company:Invitrogen

REC. PROTEIN G - SEPHAROSE from Invitrogen

Description:... G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to capture immune complexes generated in ...
Company:Invitrogen

REC PROTEIN A - SEPHAROSE from Invitrogen

Description:... G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to capture immune complexes generated in ...
Company:Invitrogen

REC PROTEIN A - HRP from Invitrogen

Description:... G conjugates are commonly used as affinity adsorbents to purify immunoglobulins (antibodies) and immunoglobulin subtypes from serum, hybridoma ascites fluids, tissue culture supernatants and other biological fluids. These reagents are also commonly used to capture immune complexes generated in ...
Company:Invitrogen

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Ascites in Biological Definition

Monoclonal antibody

... When the hybridoma cells are injected in mice (in the peritoneal cavity , the gut), they produce tumors containing an antibody-rich fluid called ascites fluid. In the above process, myeloma cell lines are used that have lost their ability to produce their own antibodies, so as to not dilute the ...
Ascites in Biological Dictionary

Polyclonal Antibody

... exist for polyclonal antibody production in laboratory animals. ... However, polyclonal antibodies in mice can be collected from ascites ... Boster Biological Technology, Ltd. has consistently focused on the manufacture, research, sale and distribution of immunological reagents. ...

Monoclonal Antibody

... system to attack the malignant tumor cells and the prevention ... UCDavis Center for Animal Alternatives Information ... Finally, the ascites fluid which contains monoclonal antibodies is harvested from the mouse. ... Monoclonal Antibody Production. A Report of the. Committee on ...

Monoclonal antibodies

... system to attack the malignant tumor cells and the prevention ... UCDavis Center for Animal Alternatives Information ... Finally, the ascites fluid which contains monoclonal antibodies is harvested from the mouse. ... CHI's PEGS: The PROTEIN ENGINEERING SUMMITis a weeklong series of ...

Clone bank

... straw, but that's why you're ... ... cell culture production, cell cloning , hybridoma screening and clone banking ... 25 mLs of ascites will be provided for each clone . ... ...
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(Date:10/30/2014)... 29, 2014 (HealthDay News) -- Scientists who used stem ... say their breakthrough could provide a new way to ... diseases. The team used human pluripotent stem cells ... the body -- to grow the functional miniature stomachs, ... a major cause of ulcers and stomach cancer. ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... milk could be bad for your health, a new study ... milk can help strengthen bones and prevent osteoporosis. These benefits ... milk as part of a healthy diet. But this ... not protect men or women from bone fractures, and was ...
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