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Aplastic in Medical News

Donate Blood - A Simple and Precious Lifegiving Gift

... that are very sick. December is also aplastic Anemia Awareness Month. aplastic anemia is a rare and serious condition where bone ... Katelyn Rose Hubbell was diagnosed with severe aplastic anemia at the age of four. She required platelet ...

A Bone Marrow Disease With a Brighter Prognosis

... New drugs, transplantation helping people with aplastic anemia live longer, fuller lives ... -- Blood is life. And the rare disease known as aplastic anemia robs the body of life by robbing the body of blood. The aplastic anemia patient's blood thins as the bone marrow ...

Survey: Few physicians support private banking of umbilical cord blood

... if a relative has, or is at risk for, a disease such as leukemia or aplastic anemia that can be treated by a stem cell transplant. Families without ... own cord blood to treat high-risk neuroblastoma, or to treat severe aplastic anemia in the absence of an available sibling donor. In addition, few ...

European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors

... myelosuppression including prolonged pancytopenia, which may result in aplastic anemia, which in some cases has resulted in a fatal outcome. In some cases, exposure to concomitant medications associated with aplastic anemia including carbamazepine, phenytoin, and ...

Cimzia(R) (certolizumab pegol) Now Available for Self-Administration in Adult Patients With Moderate to Severe Crohn's Disease

... remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been ...

UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis

... remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been ...

UBC research finds molecular "key" to successful blood stem cell transplants

... could help increase the success of blood stem cell transplants, a procedure currently used to treat diseases such as leukemia, Hodgkin's lymphoma and aplastic anemia. During a blood stem cell transplant, donor blood stem cells - which can produce red and white blood cells and platelets - are injected ...

IMPACT Study Demonstrates That Longer Prophylactic Therapy With Valcyte(R) (Valganciclovir Hydrochloride Tablets) Increases Protection Against CMV - the Most Serious Viral Infection Affecting Transplant Patients

... liter, or the hemoglobin is less than 8 g/dL. Severe leucopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, bone morrow depression, and aplastic anemia have been observed in patients treated with Valcyte tablets (and ganciclovir). Other adverse events reported with frequency of greater or ...

Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients

... retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial ...

PEGASYS(R) Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine

... suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), ...
Aplastic in Medical Technology

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... to 30x10(9)/L). Forty-five percent of the AEGIS patients had a history of aplastic anemia or myelodysplastic syndromes. Patients were dosed in accordance ... more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndromes (MDS). (8,9,10) In patients with ...

CHMP Recommends Approval in the European Union (EU) for New Options for Patients With Certain Primary Brain Tumors

... myelosuppression including prolonged pancytopenia, which may result in aplastic anemia, which in some cases has resulted in a fatal outcome. In some cases, exposure to concomitant medications associated with aplastic anemia including carbamazepine, phenytoin, and ...

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

... as a result of their disease," said John Huber, Executive Director of the aplastic Anemia & MDS International Foundation. "This news provides additional hope ... more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndrome (MDS).(14,15,16,17) In patients ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... and, rarely, in the development of a lupus-like syndrome. There have been postmarketing reports of pancytopenia, leukopenia, neutropenia, aplastic anemia, and thrombocytopenia in patients receiving TNF blockers. Cytopenias including pancytopenia, have been infrequently reported with SIMPONI in ...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

... liter, or the hemoglobin is less than 8 g/dL. Severe leukopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, bone marrow depression, and aplastic anemia have been observed in patients treated with Valcyte tablets (and ganciclovir). Other adverse events reported with frequency of greater than or ...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

... remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been ...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

... retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial ...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

... suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), ...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

... suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), ...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

... retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cytopenia and very rarely aplastic anemia), thyroiditis, dental and periodontal disorders, hemorrhagic/ischemic colitis, dyspnea, pulmonary infiltrates, pneumonia, interstitial ...
Aplastic in Medical Definition

Hematopathology

... , Warm autoimmune hemolytic anemia , Hemolytic-uremic syndrome , Microangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , ...

Pathology

... , Warm autoimmune hemolytic anemia , Hemolytic-uremic syndrome , Microangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , ...
Aplastic in Medical Dictionary

Anemia

... Bowel Disease Health Highlights ... aplastic anemia falls into three basic categories, ... acquired, and hereditary. In about 60% of cases, aplastic anemia is considered to be idiopathic , ... blood cells. It is a lifelong disease . In aplastic anemia , your body stops producing enough new ...

Aplastic

... aplastic anemia : Anemia due to failure of the bone ... and white blood cells as well as platelet s. aplastic anemia frequently occurs without a known cause. aplastic anemia occurs when the bone marrow produces ...

Aplastic anemia

... aplastic anemia : Anemia due to failure of the bone ... and white blood cells as well as platelet s. aplastic anemia frequently occurs without a known cause. aplastic anemia occurs when the bone marrow produces ...

Acne vulgaris

... Acne Vulgaris ( Acne ) Acoustic Neuroma Acoustic Trauma Acquired aplastic Anemia (Secondary aplastic Anemia ) Acquired Bronchiectasis ( Bronchiectasis ) ... Webster, GF. ...

Anaplastic thyroid cancer

... The most aggressive and fastest growing type of thyroid cancer , an aplastic cancer often can't be helped by surgery by the time it's diagnose d. ... Anaphylactoid Purpura ( Henoch -Schonlein Purpura ) Anaphylaxis An aplastic Carcinoma of the Thyroid ( Anaplastic Thyroid Cancer ) Anaplastic ...

Falls

... medications Complications of surgery ( infection , bleeding ) ... aplastic anemia falls into three basic categories, based on the origin of its cause: idiopathic , acquired, and hereditary. In about 60% of cases, aplastic anemia is considered to be idiopathic , meaning that the cause of the ...

Idiopathic

... acute mitral regurgitation ; chronic mitral valve prolapse ... aplastic anemia falls into three basic categories, based on the origin of its cause: idiopathic , acquired, and hereditary. In about 60% of cases, aplastic anemia is considered to be idiopathic , meaning that the cause of the ...

Platelet

... tendency to bleed and reduces the body's defense against infection . aplastic anemia : Anemia due to failure of the bone marrow to produce blood cells, including red and white blood cells as well as platelet s. aplastic anemia frequently occurs without a known cause. This initiates ...

Acute myelogenous leukemia

... Acute Nonlymphocytic Leukemia Agranulocytosis ALL ( Acute Lymphoblastic Leukemia ) AML ( Acute Nonlymphocytic Leukemia ) Anemia aplastic Anemia ... [5] Myelodysplastic syndrome and acute myelogenous leukemia are late complications of myeloablative therapy with autologous bone ...

Agranulocytosis

... called neutrophil s or granulocyte s. Agranulocytosis ALL ( Acute Lymphoblastic Leukemia ) AML ( Acute Nonlymphocytic Leukemia ) Anemia aplastic Anemia A PTT ( Partial Thromboplastin Time) Auto immune Thrombocytopenia ( Idiopathic Thrombocytopenic Purpura ) Bleeding Disorders Blood ...

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Aplastic in Biological News

Vidaza receives positve opinion from European CHMP

... The aplastic Anemia & MDS International Foundation is pleased to inform patients that ... in Europe with this disease," said John Huber, Executive Director of the aplastic Anemia & MDS International Foundation, "Vidaza not only extends patients' ...

FDA approves Vidaza label expansion

... Washington D.C. (August 21, 2008) The aplastic Anemia & MDS International Foundation (AA&MDSIF) is pleased to inform ... survival for MDS patients," said John Huber, Executive Director of the aplastic Anemia and MDS International Foundation. "We are excited to see that in ...

Peter Baumann named Howard Hughes Medical Institute Early Career Scientist

... team hopes to lay the foundation for the development of treatments for cancer as well as degenerative syndromes such as dyskeratosis congenita and aplastic anemia. Dr. Baumann leads an eight-person team at the Stowers Institute composed of postdoctoral researchers, graduate students, and scientific ...

Stowers Institute's Baumann Lab identifies key step in maturation pathway of telomerase

... machinery for human telomerase are also likely to compromise telomerase function and may thus contribute to diseases such as dyskeratosis congenita, aplastic anemia, and idiopathic pulmonary fibrosis." ...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

... Mutations in the RNA are associated with the inherited diseases aplastic anemia and dyskeratosis congenita, which frequently are manifested by ... of the RNA, which is essential for the function of the enzyme, and causes aplastic anemia in patients who have this mutation. "There are five known ...
Aplastic in Biological Technology

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

... as a result of their disease," said John Huber, Executive Director of the aplastic Anemia & MDS International Foundation. "This news provides additional hope ... more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndrome (MDS).(14,15,16,17) In patients ...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... remains unclear. Exercise caution in considering the use of CIMZIA in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been ...

Transplant Program Tops in Expected One-Year Survival Rate

... patient age and degree of donor cell match. Stem-cell and bone-marrow transplants are used to treat various leukemias, lymphomas and severe aplastic anemia. "The study's findings reflect the extraordinary and longtime dedication by the staff of the Hutchinson Center and SCCA to improve the ...

Soliris(R) Reduced Measures of Thrombosis and Inflammation, and Decreased Indicators of Pulmonary Hypertension, in Studies of Patients with PNH

... 15 years from the time of diagnosis. (4,6) PNH has been identified more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndromes (MDS). (7, 8, 9). In patients with thrombosis of unknown origin, PNH may be an underlying cause. (5,10) ...

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

... unclear. Exercise caution in considering the use of CIMZIA (R) in patients with these disorders. Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF blockers. Medically significant cytopenia (e.g., leukopenia, pancytopenia, thrombocytopenia) has been ...

Alexion's Soliris(R) Receives 2008 Prix Galien USA Award for Best Biotechnology Product

... 10 and 15 years from the time of diagnosis. (2,4) PNH has been identified more commonly among patients with disorders of the bone marrow, including aplastic anemia (AA) and myelodysplastic syndrome (MDS). (5,6,7,8,9) In patients with thrombosis of unknown origin, PNH may be an underlying cause. (3,9) ...

Cord Blood America CEO Matthew Schissler Interviewed by BIONOVA, Greece's Leading Biotech Magazine

... in 2006 named a.bourkas Co., United. "Stem cells are used today in the treatment of leukemia, breast cancer, lymphoma, Hodgkin's Disease, aplastic anemia, sickle cell anemia, various other cancers, blood diseases, hereditary and genetic conditions and immune system disorders," Mr. Schissler said ...

Abbott's HUMIRA(R) Receives Positive Opinion From EMEA for Treatment of Moderate to Severe Plaque Psoriasis

... HUMIRA, have been associated in rare cases with demyelinating disease and serious allergic reactions. Rare reports of pancytopenia including aplastic anemia have been reported with TNF-blocking agents. Adverse events of the haematologic system, including medically significant cytopenia have been ...

Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes

... should not nurse. About MDS The highest prevalence of MDS is in patients over 60 years of age. According to the American Cancer Society and the aplastic Anemia and MDS International Foundation, there are approximately 10,000 - 30,000 new cases of MDS in the United States each year. Survival ranges ...
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