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Antigens in Medical News

Dendritic cells ensure immune tolerance

... surface for recognizing just one single antigen. antigens are molecular structures, mostly fragments of ... they rely on other cells which can present antigens to them. It is the dendritic cells that are ... other things, they are specialized in presenting antigens to T cells, which is what makes an immune ...

TB breakthrough could lead to stronger vaccine

... been made to improve the vaccine by incorporating antigens (molecular components of the bacteria) to induce ... at Houston. Tuberculosis hides in cells so the antigens are not recognized by the immune system. The BCG ... movement of particles in cells, would cause BCG antigens to enter pathways leading to improved ...

Frost & Sullivan Lauds Aesku.Diagnostics For Providing an Overall Analysis Platform For a Wide Range of Autoimmune Complications

... tests are developed based on human recombinant antigens or native antigens (conformational epitopes) depending on the ... CE marked kits incorporating human recombinant antigens synthesized in-house to assure maximum ...

NIH scientists discover crucial control in long-lasting immunity

... displayed on the surface of the B cell. These antigens signal to T cells, which have specialized receptors that can bind to antigens on the B cells. Thus coupled, the T cells deliver ... SAP do not bind strongly to B cells carrying antigens the T cells otherwise could recognize. "The ...

Also in the June 24 JNCI

... Intestinal Proteins May Be Effective Anti-Tumor antigens Mice immunized with an intestinal protein ... the development of cancer vaccines by a lack of antigens that are specific for tumors and not expressed elsewhere in the body. Immunization with antigens that are expressed elsewhere in the body raises ...

Different type of colon cancer vaccine reduces disease spread, Jefferson scientists show

... is the lack of immune system-alerting protein antigens that are specific for tumors only. According to ... and metastasize, carrying with them all the antigens that typically reside in the mucosal system. They ... researchers suggest that this approach of using antigens from tumors originating in immune-restricted ...

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Antigens in Medical Technology

Vical Pandemic Influenza Vaccines Achieve T-Cell Responses and Cross-Clade Reactivity in Humans

... responses against the matching H5 antigen and the conserved NP and M2 antigens were detected in a majority of subjects receiving the trivalent vaccine. Responses against conserved antigens could provide protection against serious disease or death during an ...

Multi-Pronged Therapeutic Cancer Vaccine Regimen to be Studied in Melanoma Patients

... immune responses in humans. The ALVAC(2) virus contains the genes for five antigens -- molecules that induce an immune response -- that are commonly found in melanoma tumors. These antigens stimulate T-cells within the immune system to hone in on melanoma cells, ...

Intercell AG to Acquire Iomai Corporation to Expand Late Stage Product Pipeline and Strengthen Leadership in Vaccine Innovation

... leading vaccine technologies, specifically a delivery platform for antigens and adjuvants that can facilitate the development of a broad range of ... diseases with substantial unmet medical need. The Company develops antigens and adjuvants which are derived from its proprietary technology platforms ...

AlphaVax Announces Initial Analysis of Data From CMV Phase 1 Clinical Trial

... developed substantial antibody or T cell responses to all three CMV antigens in the vaccine. Preliminary results suggest that both the CD4 and CD8 ... readily detectable immune responses to all three vaccine-expressed antigens and at both dosage levels. It is these types of responses, both cellular ...

A Functional Immune System Can Be Derived From Embryonic Stem Cells, Preliminary Study Finds

... bone marrow, umbilical cord blood, and peripheral blood from donors. The antigens on the surface of donated cells must be compatible (determined by a method ... rejection. The use of embryonic stem cells, which have low levels of these antigens and may therefore be less likely to provoke a defensive reaction by the ...

CEL-SCI Corporation Releases Letter to Shareholders

... on a tumor and attack that tumor only in one way. There are many antigens that need to be attacked to overcome the very complex tumor defense mechanisms and the constant mutation of the tumor antigens cannot be addressed with a 'one key fits all' approach. 3) They act ...

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Antigens in Medical Products

Directigen EZ Flu A+B Test Kit

Description:... qualitative detection of influenza A and B viral antigens from nasopharyngeal washes/aspirates and throat ... differentiated test, such that influenza A viral antigens can be distinguished from influenza B viral antigens from a single processed sample using a single ...
Company:BD Diagnostic Systems

Pastorex® Staph Plus Kit

Description:... possess a capsule which can mask cell wall antigens (clumping factor and protein A) typically ... however, simultaneously detects both cell wall antigens and capsular antigens in culture media isolates. Pastorex® Staph ...
Company:Bio-Rad Laboratories

Sanochemia Fluorognost HIV-1 IFA Confirmation Assay

Description:... Blot): The assay uses immortalized human T-cells which express HIV-1 antigens on their surface. The cells are fixed to the surface of an IFA glass ... or plasma sample with HIV- I antibodies comes in contact with the HIV-1 antigens on the slide, antigen/antibody binding takes place. The interpretation of ...
Company:Sanochemia

Autoimmunity ENA/DNA Screening Panel

Description:... reagent system used in most western blot assays. ENA/DNA combines antigens detected in Auto 4 detecting the four common extractable nuclear antigens (ENA): RNP, Sm Antigen, SS-A (Ro) and SS-B (La) and also detects dsDNA ...
Company:GenBio

Candida albicans IgG / IgM / IgA ELISA

Description:... protocols for detection of IgG, IgM, and IgA antibodies. All of the ELISA antigens used in Virion\Serions assay systems are produced in their own laboratories under the control of their experienced staff. These antigens are inactivated and non-infectious and available to our customers as ...
Company:QED Bioscience Inc.

AUTOSTAT II ENA 6 Profile

Description:... an important tool in the diagnosis of systemic rheumatic diseases. The antigens used in their detection are purified by the saline extraction of human or animal nuclei, this has led to them being termed Extractable Nuclear antigens (ENAs). The most commonly measured ENA specifications are anti-SS-A/Ro, ...
Company:Hycor Biomedical Inc.

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Antigens in Medical Definition

Central tolerance

... of the cells generated are self-reactive (recognise the component self antigens of the host). In mammals the process occurs in the thymus (T cells) ... (B cells), when maturing lymphocytes are exposed to self antigens. Self antigens are present in both organs due to endogenous expression within the organ ...

Artificial induction of immunity

... ways in researching the immune system. A more contemporary approach for "boosting" the immune response of simpler immunogenic molecules (known as antigens ) is to conjugate the antigens. Conjugation is the attachment to the antigen of another substance which also generates an immune response, thus ...

Heterophile

... term, like "heterosexual" in Canada and the United States. Medical Heterophile Antibodies are antibodies induced by external antigens (Heterophile Antigens) that nevertheless cross-react with self-antigens. For example antibodies against Group A Streptococcus cell walls can also ...

Thymocyte

... of the thymus showing the cortex and medulla Minute structure of thymus. The ability of T cells to recognise foreign antigens is mediated by the T cell receptor , which is a surface protein able to recognise short protein sequences ( peptides ) that are presented on MHC . ...
Antigens in Biological News

Implants mimic infection to rally immune system against tumors

... plastic disks impregnated with tumor-specific antigens and implanted under the skin can reprogram the ... an implant's pores, where they are exposed to antigens specific to the type of tumor being targeted. The ... could also be loaded with bacterial or viral antigens to safeguard against an array of infectious ...

'Femtomolar optical tweezers' may enable sensitive blood tests

... containing infectious particles (antigens). The antigens then stick to the antibodies on the sphere, ... force needed to break off the antibodies from the antigens and thus count the number of individual antigens that were bound to the sphere. This in turn can ...

The right messenger for a healthy immune response

... fragments of pathogens, so-called antigens. Immune cells present these antigens on their surface and in this way communicate with one another: antigens are the "wanted posters" of the virus or the bacterium which has to be ...

UTSA, Health Science Center collaborate with Merck & Co. to develop chlamydia vaccine

... a vaccine composed of a select group of recombinant C. trachomatis antigens can successfully accelerate bacterial clearance, and importantly, preserve ... working hard with the Merck group to identify the most efficacious vaccine antigens for inducing anti-chlamydial immunity. They are also planning to apply ...

Molecule that suppresses immune response under study in type 1 diabetes

... that hurts IDO expression. Dendritic cells, which can express IDO, show antigens to the T-cells. A Journal of Immunology paper last year reported that ... which causes dendritic cells to express IDO, at the same time they give antigens to the insulin-producing cells. "The presence of the antigen excites the T ...

Forsyth scientist receives major grant to support rapid, accurate, affordable test for tuberculosis

... a methodology that allows us to detect minute traces of the TB antigens that are excreted in the urine by a TB-infected patient. What is so ... current sample collection, is completely non-invasive the presence of TB antigens in urine may be detectable earlier than through other samples, leading to ...

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Antigens in Biological Technology

ImmunoVaccine Technologies Licenses Immunotope's Breast, Ovarian and Prostate Cancer Antigens

... an agreement to exclusively license seven cancer antigens from Immunotope Inc., an antigen discovery company. These proprietary antigens specifically target breast, ovarian and prostate cancers. IVT will combine the proprietary antigens with its DepoVax(TM) delivery platform to develop ...

Medicago succesfully expresses VLP antigen for A H1N1 strain

... production allowing for immediate access to the antigens of emerging influenza strains. Current influenza ... system which produces recombinant vaccine antigens in non-transgenic plants. This technology has ... strikes and to supply large volumes of vaccine antigens to the world market. Additional information about ...

Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth

... be designed to bind to well established target antigens of conventional monoclonal antibodies, but also ... Officer Dr. Patrick A. Baeuerle. "Many target antigens for cancer therapy are released by cancer cells ... BiTE antibody suggests that high levels of shed antigens may not pose a limitation for the anti-tumor ...

ImmunoVaccine Technologies Partners With Scancell to Advance DNA Vaccine Delivery

... liposomes, adjuvants and oil. DepoVax(TM) enhances the immunogenicity of antigens in general, and can be used to dramatically enhance the delivery of polynucleotide-based antigens and SiRNA to lymph nodes. IVT has proven its scale-up capabilities at a ...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

... using a transient expression system which produces recombinant vaccine antigens in non-transgenic plants. This technology has potential to offer ... first wave of a pandemic strikes and to supply large volumes of vaccine antigens to the world market. Additional information about Medicago is available at ...

Morphotek(R), Inc. Announces a Research Collaboration Agreement with Synageva BioPharma Corporation to Develop Potential Treatments for Cancer and Infectious Disease

... has assembled a portfolio of lead human and humanized antibodies to antigens associated with cancer, neovascular, inflammatory and infectious disease. The antibodies within the company's pipeline are targeted against antigens licensed from its collaborative partners. About Morphotek ...

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Antigens in Biological Products

PicTure - Double Staining Kit from Invitrogen

Description:... is a technique used to reveal two distinct antigens in a single tissue.(1-6) PicTure™-Double ... staining detection method for detecting two antigens simultaneously in the same human cell or tissue sample with increased sensitivity. The antigens can be identified using two different primary ...
Company:Invitrogen

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (10X) from Lab Vision

Description:... fixation impairs or totally destroys the immunoreactivity of many antigens and epitopes. The negative effect of formaldehyde fixation can be ... have been recently introduced to improve the immunoreactivity of many antigens in formaldehyde fixed tissues. Heat-Induced Epitope Retrieval (HIER) in ...
Company:Lab Vision

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (100X) from Lab Vision

Description:... fixation impairs or totally destroys the immunoreactivity of many antigens and epitopes. The negative effect of formaldehyde fixation can be ... have been recently introduced to improve the immunoreactivity of many antigens in formaldehyde fixed tissues. Heat-Induced Epitope Retrieval (HIER) in ...
Company:Lab Vision

Complete Adjuvant from Santa Cruz Biotechnology, Inc.

Description:... Incomplete Freund's adjuvant is used for the subsequent boosts. antigens (preferably in saline) are typically mixed with an equal volume of the ... Adjuvants may be used to produce water-in-oil emulsions of immunogens. antigens in water-in-oil emulsions stimulate high and long-lasting antibody ...
Company:Santa Cruz Biotechnology, Inc.

IHC SELECT® APR KIT SINGLE SPECIES-RAT 150 TESTS from CHEMICON

Description:... which contain rat and goat IgG for the qualitative identification of antigens by light microscopy in paraffin-embedded tissues. The IHC Select ... goat IgG in the Primary Antibody. The primary antibody binds to specific antigens present in the specimen. Any excess antibody is removed by washing. Next, ...
Company:CHEMICON

Anti-Rat HRP-DAB Cell & Tissue Staining Kit from R&D Systems

Description:... R&D Systems Cell and Tissue Staining Kits are intended for localization of antigens in a broad range of histological and cytological specimens. These kits may ... Complex (ABC) with primary antibodies that reacted with tissue antigens under study. Visualization is based on enzymatic conversion of a ...
Company:R&D Systems

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Antigens in Biological Definition

Antibody

... of the monomer. The two variable domains bind the antigens they are specific for and that elicited their ... The ability to bind a wide variety of foreign antigens arises from events know as somatic recombination. ... human immune system is capable of binding so many antigens is the variable region of the heavy chain. More ...

Antigen

... injected or comes into contact with skin. antigens are presented by a cell to its environment via a ... can leap into action. We can also classify antigens according to where they come from: Exogenous antigens ...

Blood type

... ABO and Rh factor . There are 46 other known antigens , most of which are much rarer than ABO and Rh. ... blood types along with their respective antigens and antibodies : Individuals with type A ... Type AB people have red blood cells with both antigens A and B, and do not produce antibodies against ...

T cell

... to destroy target cells which express specific antigens that they recognize. Helper T cells (CD4 + ... . CD4 and CD8 refer to the characteristic antigens on the surface of the different sub-types of ... where they get presented with self and foreign antigens in a complex with type I and type II MHC ...

Immunology

... of classical immunology has been the interaction between antibodies and antigens . Without an understanding of the properties of these two biological ... disease ), and autoimmunity , in which the immune system attacks its own antigens (examples include systemic lupus erythematosus , rheumatoid arthritis , ...

Major histocompatibility complex

... peptides. Foreign peptides that provoke an immune response are termed antigens . Interestingly, the immune system has another, equally important method ... B cell receptors (BCRs). However, while the BCRs of B cells can bind to antigens without much outside help, the TCRs of T cells require "presentation" of ...

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Antigens in Biological Dictionary

Antigens

... on chromosome 6, and ... recognize antigens and factors that contribute to their ... of immune responses made to different types of antigens . ... antigens and Antibodies | World of Anatomy and ....

Antibodies

... . Anti-Feline Secondary Antibodies ... antigens and Antibodies | World of Anatomy and Physiology. antigens and Antibodies summary with 7 pages of ... a memory system which detects and links antigens to an effector system that defends against the ...

Rhesus factor

... The term Rhesus (Rh) blood group system refers to the 5 main Rhesus antigens as well as the many other less frequent Rhesus antigens. The terms ... The term Rhesus (Rh) blood group system refers to the 5 main Rhesus antigens (C, c, ... An agglutinable factor in human blood ... The Rhesus ...

Immune response

... especially one mediated by lymphocytes and involving recognition of antigens by The immune response is how your body recognizes and defends ... how your body recognizes and defends itself against ... T cells attack antigens directly and help control of the immune response . ... For an ...

Histocompatibility

... Histocompatibility Molecules ... Histocompatibility molecules present antigens to T cells ... Translations of histocompatibility . ... ... The Histocompatibility Laboratory performs Human Leukocyte antigens (HLA) ... histocompatibility gene. histocompatibility antigen. ...

T lymphocytes

... cells) differentiate ... T cell n. Any of the lymphocytes that mature in the thymus and have the ability to recognize specific peptide antigens through the receptors on their T lymphocytes Specialized blood cells that recognize invading organisms (helper T lymphocytes ) and ...

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