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Antigenic in Medical News

Universal Capital Management Reports Vystar(TM) Corporation Receives FDA Clearance for Envy(TM) Natural Rubber Latex Condom Made with Vytex(TM) NRL

... virtually undetectable levels, of the antigenic proteins that can cause an allergic response, ... will carry labeling that will reflect the lowest antigenic protein content currently available in a natural ... latex condom with this level of reduction in antigenic proteins to the U.S. market. The Envy condom ...

Vytex(TM) Natural Rubber Latex Manufacturing Test Results Get International Latex Conference Buzzing

... available NRL source material has ultra low antigenic protein levels as raw material while preserving ... NRL that is modified to significantly reduce its antigenic protein content. He pointed out that this ... show that in addition to significantly reduced antigenic protein levels; products made with Vytex NRL ...

JCI online early table of contents: Feb. 7, 2008

... failed to migrate and to accumulate in the antigenic tissue, meaning that an immune response was not ... that inhibits PI3K p110-delta did not migrate to antigenic tissues activated by an inflammatory stimulus. ... activity is required for T cell localization to antigenic tissue in mice AUTHOR CONTACT: Federica ...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune/T-cell binding ligand (I/TCBL) can be ...

Frost & Sullivan Lauds Toscana Biomarkers' Outstanding Contributions to the R&D of Novel Biomarkers for the Diagnosis of Autoimmune Diseases

... [chemical reverse approach (CRA)], which indicates that the screening of antigenic probes is primarily guided by the antibodies circulating in a patient's ... Suraj Ramanathan. "These peptides could be further screened and used as antigenic probes for the detection of potential biomarkers for each specific ....

CEL-SCI Launches Study to Determine Long Lasting Beneficial Effects of its Rheumatoid Arthritis Vaccine

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to a T-cell binding ligand (TCBL) can be ...

NIH scientists discover crucial control in long-lasting immunity

... it is as if the arms of the T-cell receptor cannot firmly grasp the antigenic arms of the B cell, and thus the tango between the two immune cells does ... to dendritic cells without any problems, although dendritic cells have antigenic arms similar to those of B cells. Dr. Cannons explains, "Some cell ...

Vystar Corporation and Revertex Malaysia Sign Vytex(TM) NRL Production Contract

... breakthrough in the global search for a natural rubber latex in which the antigenic proteins that trigger allergic reactions are deactivated without reducing ... Ongoing test results consistently show that the Vytex technology reduces antigenic proteins to levels considered undetectable by the most widely used ...

URI awarded $13 million grant to develop vaccines for emerging infectious diseases

... immunome-derived vaccines have the potential to be safer and more effective since they focus the protective immune response on the most essential antigenic elements of the pathogenic bacteria or virus, while eliminating potentially cross-reactive and deleterious or simply inert components, reducing the ...

InDevR's FluChip detects and distinguishes swine-origin H1N1 from human influenza viruses

... proteins. Current qRT-PCR subtyping assays target a more highly mutable gene that codes for a protein, hemagglutinin (HA), which is subject to antigenic drift. "As has happened in the past, if the HA gene changes in a critical region, qRT-PCR will fail and the researcher won't know why until the gene ...

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Antigenic in Medical Technology

Data Suggest CEL-SCI's CEL-2000 Vaccine Prevents or Retards Permanent Damage of Rheumatoid Arthritis

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... with synthetic peptides. The L.E.A.P.S.(TM) constructs containing the antigenic disease epitope linked to a T-cell binding ligand (TCBL) can be ...

MabVax Therapeutics Closes Two Licensing Agreements With Sloan-Kettering Institute for Cancer Research

... 25 years have developed monovalent cancer vaccines against ten distinct antigenic targets on various types of cancer cells. These vaccines target gangliosides and other carbohydrate antigens that are the most extensively expressed antigenic targets on the cell surface of certain cancers. Vaccines, or passively ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... is a novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune diseases and allergies, are potential therapeutic or preventive ...

Novavax Reports Positive Preclinical Results for a Novel, Broadly Cross-Protective H5N1 Pandemic Influenza Virus-like Particle (VLP) Vaccine Candidate

... without the use of an adjuvant. "It is extremely important to identify a pre-pandemic vaccine candidate which is able to protect against different antigenic variants of H5N1 virus that are circulating broadly," said Dr. Honglin Chen. H5N1 avian influenza viruses emerged in humans in Hong Kong in 1997 ...

AVI BioPharma Reports Positive Pre-Clinical Influenza Data

... is an enveloped negative-strand RNA virus, with eight genome segments that code for 10 proteins. Influenza strains are subtyped according to the antigenic and genetic nature of their surface glycoproteins: hemagglutinin (HA or H) and neuraminidase (NA or N). Fifteen H and nine N subtypes have been ...
Antigenic in Medical Products

Insulin Jumbo EIA Diabetes and Obesity Markers 008-10-1113-99

Description:... technique in which two monoclonal antibodies are directed against separate antigenic determinants on the human insulin molecule. During incubation, insulin in ... technique in which two monoclonal antibodies are directed against separate antigenic determinants on the human insulin molecule. During incubation, insulin in ...
Company:ALPCO Diagnostics

Cyto-Chex Storage and Transport Solution

Description:... Cyto-Chex is a storage and transport solution formulated to preserve the white blood cells in samples without reducing the activity of antigenic sites. Samples treated with Cyto-Chex can be stored for up to seven days prior to analysis by flow cytometry. Cyto-Chex offers 1-year closed-vial ...
Company:Streck

C6 B. burgdorferi (Lyme) ELISA Kit

Description:... of the surface protein VlsE. This peptide has been shown to represent the immunodominant portion of VlsE, containing substantially all of the antigenic reactivity of the whole protein. Recent studies have shown that the C6 peptide is a sensitive and specific marker for antibody to B. burgdorferi ...
Company:Immunetics, Inc.

Human Myoglobin Enzyme Immunoassay

Description:... the principle of a solid phase enzyme-linked immunosorbent assay. The assay system utilizes a unique monoclonal antibody directed against a distinct antigenic determinant on the myoglobin molecule. Mouse monoclonal anti-myoglobin antibody is used for solid phase immobilization (on the microtiter wells). A ...
Company:Diagnostic Automation, Inc.

Iso-Insulin ELISA

Description:... phase two-site enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the insulin molecule. During incubation insulin in the sample react with peroxidase-conjugated anti-insulin antibodies and ...
Company:IDS Ltd

C-Peptide EIA Diabetes and Obesity Markers 008-10-1136-01

Description:... phase two-site enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the C-peptide molecule. During incubation, C-peptide in the sample reacts with peroxidase-conjugated anti-C-peptide antibodies and ...
Company:ALPCO Diagnostics

Insulin EIA Diabetes and Obesity Markers 008-10-1113-01

Description:... phase two-site enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the human insulin molecule. During incubation, insulin in the sample reacts with peroxidase-conjugated anti-insulin antibodies and ...
Company:ALPCO Diagnostics

Ultrasensitive C-Peptide EIA Diabetes and Obesity Markers 008-10-1141-01

Description:... phase two-site enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the C-peptide molecule. During incubation, C-peptide in the sample reacts with peroxidase-conjugated anti-C-peptide antibodies and ...
Company:ALPCO Diagnostics

Insulin Ultrasensitive EIA Diabetes and Obesity Markers 008-10-1132-01

Description:... is a solid phase enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the human insulin molecule. During incubation, insulin in the sample reacts with peroxidase-conjugated anti-insulin antibodies and ...
Company:ALPCO Diagnostics

Iso-Insulin EIA Diabetes and Obesity Markers 008-10-1128-01

Description:... phase two-site enzyme immunoassay. It is based on the direct sandwich technique in which two monoclonal antibodies are directed against separate antigenic determinants on the human insulin molecule. During incubation, insulin in the sample reacts with peroxidase-conjugated anti-insulin antibodies and ...
Company:ALPCO Diagnostics

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Antigenic in Biological News

Tracking influenza's every movement

... makeup of each virus. The team used this information to create an antigenic map which visually shows the relationships between all the different ... with the Santa Fe Institute, to develop the methods and software to build antigenic maps. This work is highly multidisciplinary, with epidemiologists, ...

7th annual [BC]2 Basel Computational Biology Conference 'Molecular Evolution' June 18-19, 2009

... including man. Derek Smith, Professor of Infectious Disease Informatics, Department of Zoology, University of Cambridge, UK, will present on "The antigenic evolution of influenza viruses". He will describe the study of influenza virus evolution, required for influenza vaccine strain selection. Derek is ...

Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

... stem, perhaps because it is less accessible than the head region. In this study, the scientists used recombinant purified protein, not virus, so the antigenic part of the virus recognized by the antibodies was fully exposed. Seasonal influenza occurs each year, causing mild to severe illness. Worldwide, ...

Scientists identify human monoclonal antibodies effective against bird, seasonal flu viruses

... stem, perhaps because it is less accessible than the head region. In this study, the scientists used recombinant purified protein, not virus, so the antigenic part of the virus recognized by the antibodies was fully exposed. Seasonal influenza occurs each year, causing mild to severe illness. Worldwide, ...

American Society for Microbiology honors Eric Skaar

... in research in microbiology and infectious diseases. While a graduate student at Northwestern, Dr. Skaar focused on the molecular mechanisms of antigenic variation in the Gram-negative pathogen Neisseria gonorrhoeae. His research described novel systems used by N. gonorrhoeae to combat the oxidative ...

A protein sequence associated with Huntington’s disease may become life-saving vaccine component

... First, he noticed that small aggregates formed by an antigen fused to a polyQ tail resembled the droplets that conventional adjuvants formed with antigenic peptides exposed on their surface. Dr. Shneider hypothesized that these polyQ containing aggregates were easily taken up by antigen-presenting ...

Paracetamol, one of most used analgesics, could slow down bone growth

... process). Application of this plasma gel on bones accelerates their growth, without affecting other cell parameters such as the cell cycle or the antigenic profile. It is therefore an easy technique which involves few risks for the patient, who will recover from bone defects more quickly. Even ...

Protein splicing upsets the DNA colinearity paradigm

... function of 'antigen processing,' which produces antigenic peptides; the 'red flags' that mark cells for ... by another person - when T lymphocytes recognize antigenic peptides displayed on the cell surface. The ... that significantly extends the number of antigenic peptides that can be produced from a single ...

Breakthrough System for Understanding Ocean Plant Life Announced

... are somehow silenced. This genetic trick, called antigenic variation, has severely limited sleeping sickness ... role in the gene silencing process behind antigenic variation. With the goal of learning how the organism regulates the process of antigenic variation, the scientists have been trying to ...

Newly discovered protein an important tool for sleeping sickness research

... are somehow silenced. This genetic trick, called antigenic variation, has severely limited sleeping sickness ... role in the gene silencing process behind antigenic variation. With the goal of learning how the organism regulates the process of antigenic variation, the scientists have been trying to ...

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Antigenic in Biological Technology

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

... and promotes good immunological recall following antigenic challenge. In addition, a lower incidence of ... (at one of two dose levels followed by an antigenic challenge dose, i.e., a dose to show that the ... the original dose, on either day 182 or 364. The antigenic challenge dose (50 or 100 Microgram) each subject ...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune/T-cell binding ligand (I/TCBL) can be ...

Oncothyreon announces clinical data from three product candidates presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... a global Phase 3 trial of Stimuvax known as START (Stimulating Targeted antigenic Responses To NSCLC). START is a randomized, double-blind, ... a global Phase 3 trial of Stimuvax known as START (Stimulating Targeted antigenic Responses To NSCLC). START is a randomized, double-blind, ...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune/T-cell binding ligand (I/TCBL) can be ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune / T-cell binding ligand (I/TCBL) can ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or ... surface with synthetic peptides. The L.E.A.P.S. constructs containing the antigenic disease epitope linked to an Immune / T-cell binding ligand (I/TCBL) can ...

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

... were observed between groups that received different dose levels. An antigenic challenge dose was given at either day 182 or day 365. A significant response was seen in all groups that received an antigenic challenge, but no significant difference in the level of that response was ...

Oncothyreon announces presentation of long-term Stimuvax data at World Conference on Lung Cancer

... destroy cancer cells expressing MUC1. Merck KGaA currently is conducting a global Phase 3 trial of Stimuvax known as START (Stimulating Targeted antigenic Responses To NSCLC). START is a randomized, double-blind, placebo-controlled study that will evaluate patients with documented unresectable stage III ...

Oncothyreon announces initiation of Phase 3 trial of Stimuvax in breast cancer

... expressing MUC1. In addition to STRIDE, Merck KGaA currently is conducting a global Phase 3 trial of Stimuvax known as START (Stimulating Targeted antigenic Responses To NSCLC). START is a randomized, double-blind, placebo-controlled study that will evaluate patients with documented unresectable stage III ...

ImmunoVaccine Technologies Partners with FIT Biotech to advance a therapeutic HIV vaccine

... the virus to mutate rapidly. FIT Biotech has addressed this challenge by designing a synthetic DNA plasmid, known as GTU(R) MultiHIV that covers the antigenic variability within HIV strains. GTU(R) MultiHIV and is comprised of the multi-epitope/multivalent HIV antigens. As FIT Biotech's lead vaccine ...
Antigenic in Biological Products

Western-Re-Probe Reagent from Calbiochem

Description:... and remove antibodies from membrane-bound proteins without destroying antigenic binding capacity. Recommended for stripping chemiluminescent or ... remove antibodies from the membrane bound protein without destroying the antigenic binding ....
Company:Calbiochem

Concentrated Epitope Retrieval Buffer-Reduced pH from Bethyl Laboratories

Description:... Bethyl Laboratories Epitope Retrieval Buffer-Reduced pH will unmask antigenic sites from formaldehyde fixation and allow for subsequent immunostaining. Shelf-Life: 1 year from date of ...
Company:Bethyl Laboratories

IHC SELECT® APR KIT SINGLE SPECIES-RAT 150 TESTS from CHEMICON

Description:... complex. The alkaline phosphatase activity on the chromogenic substrate results in the deposit of red insoluble precipitate at those antigenic sites containing the specific epitopes recognized by the primary antibody. Tissues processed in a variety of fixatives including neutral buffered ...
Company:CHEMICON

IHC SELECT® DAB KIT SINGLE SPECIES-RAT 150 TESTS from CHEMICON

Description:... complex. The HRP activity on the chromogenic substrate results in the deposit of brown to black insoluble precipitate at those antigenic sites containing the specific epitopes recognized by the primary antibody. Tissues processed in a variety of fixatives including neutral buffered ...
Company:CHEMICON
Antigenic in Biological Definition

Antigenic shift

... antigenic shift is the process by which two different ... influenza strain, it may be highly dangerous. antigenic shift is contrasted with antigenic drift which is the natural mutation over time ...

Avian influenza

... H7 and H9 are known to be capable of crossing the species barrier from birds to humans. It is feared that if the avian influenza virus undergoes antigenic shift with a human influenza virus, the new subtype created could be both highly contagious and highly lethal in humans. Such a subtype could cause ...

Vaccine

... A vaccine is an antigenic preparation used to produce active immunity to a disease, in order to prevent or ameliorate the effects of infection by any natural or 'wild' ...
Antigenic in Biological Dictionary

Antigenic variation

... antigenic variation is the process by which an ... evade a host immune response. This change in antigenic profile may occur as the pathogen passes ... organisms that target ... The term antigenic variation refers to the mechanism in which an ...

Antigenic shift

... antigenic shift is the process by which at least two ... antigens of the two original strains. The term antigenic ... antigenic shift ( ′antə¦jenik ′ shift ) ( virology ) ...

Antigenic determinant

... An epitope, also known as antigenic determinant , is the part of a macromolecule that ... Dictionary.com with free online dictionary, ... antigenic determinant . determinants of personality. list ... pronunciation, synonyms, and translation of antigenic determinant . ... Also called ...

Epitope

... An epitope , also known as antigenic determinant, is the part of a macromolecule that is recognized by the ... View other revisions Administration ... An epitope (also known as an antigenic determinant) is a biological structure or ... The use of epitope tagging ...

Vaccine

... amount of an agent that resembles a microorganism. The agent stimulates the body's immune system ... Vaccination is the administration of antigenic material (the vaccine ) to produce immunity to a disease. Vaccines can prevent or ameliorate the effects of infection by a pathogen. Vaccination is ...

Peptide-binding groove

... at both terminal ends, with a potentially ... The floor of the peptide - binding groove contains an unusual β bulge, not seen in ... an antigenic peptide engineered to replace the groove binding region of Ii ... ... of the peptide looping up and out of the peptide binding groove ...

Effector cell

... cells expressing the degranulation associated ... and ability to estimate cytotoxic effector cell frequency, the GrB ELISPOT assay ... antigenic stimulation down-regulates CCR7 on effector T cells . ... Moreover, P14.CCR7 effector cells localized almost exclusively in the splenic ... ...

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