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anthracis in Medical News

Is a cup of tea really the answer to everything -- even anthrax?

... revealed how the humble cup of tea could well be an antidote to Bacillus anthracis more commonly know as anthrax. As a nation, Brits currently drink ... of tea to bring solace and steady the mind, and to inactivate Bacillus anthracis and its toxin, perhaps the Boston Tea Party was not such a good idea after ...

Researchers find possible target to treat deadly bloodstream infections

... of anthrax infections," Samant said. "We found that, similar to E. coli, anthracis bacilli that could not biosynthesize nucleotides also were unable to grow ... at the University of Illinois Medical Center at Chicago, showed Bacillus anthracis mutants that were unable to synthesize nucleotides were not able to infect ...

PharmAthene and Medarex Announce Additional $0.8 Million U.S. Government Appropriation for Continued Development of Anthrax Therapeutic Valortim(TM)

... anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium. The investigational antibody is designed to target a protein ... including: (1) lack of activity against the toxins produced by the B. anthracis bacteria (2) need for long-term dosing to achieve full protection, ...

Elusys Therapeutics and Lonza Enter Into Manufacturing Agreement

... Anthim Background Anthim is a high-affinity, humanized and deimmunized monoclonal antibody that targets the protective antigen of B. anthracis and neutralizes the lethal effects of anthrax toxins. It is being developed for prevention and treatment of inhalation anthrax. Anthim has been ...

Scott Miller and Company Premieres "A CALL TO ARMS 2009 EDITION" at the Camelot Theaters in Palm Springs

... against many naturally occurring anthrax strains. Vaccines created from killed anthrax cultures, which contain a significant fraction of B. anthracis capsid protein, have proven to be effective against a wide-range of anthrax strains. Killed anthrax vaccines are typically given to farm animals ...

Researchers Pursuing Nasal Anthrax Vaccine

... published in the April issue of Clinical and Vaccine Immunology . Anthrax is the infection caused by the naturally occurring bacterium Bacillus anthracis . These spore-forming bacteria are found in wild and domestic animals, such as camels, goats, sheep, cattle and deer. Spores can live in the soil ...

Key Anthrax Virulence Factor Discovered

... cells called macrophages use to kill pathogens. That research involved Bacillus subtilis , a close relative of the anthrax pathogen, Bacillus anthracis . In the present study, the team found that when they mutated the bNOS gene in the anthrax pathogen, the resulting bacteria were far more ...

Southern Research Institute Names Vladimir Yamshchikov Director of Infectious Disease Research Department in Birmingham

... with both animal and human risk group Level 3 pathogens, including highly-pathogenic avian influenza (HPAi), West Nile, SARS viruses and Bacillus anthracis (anthrax). About Southern Research Institute Southern Research Institute is a not-for-profit organization that conducts basic and applied research ...

Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

... 11:15 AM, Hall D: -- Poster A-1435, titled "Pharmacokinetic-Pharmacodynamic (PK-PD) Assessment of Faropenem (FAR) in a Lethal Murine-Bacillus anthracis (BA) Inhalation Post-Exposure Prophylaxis Model." REP8839 Presentation Thursday, September 20 at 10:00 AM, Room E253D: -- Poster F1-2116, ...

Anthrax Attack - Greater Potential Threat Than Thought

... to have had anthrax, and 12 with no known B. anthracis exposure. The results: Immune responses ... the incidence of both subclinical and clinical B. anthracis infection. In an accompanying editorial, ... data suggest that cell-mediated responses in B. anthracis infection may be more sensitive than antibody ...

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anthracis in Medical Technology

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... model, Valortim(R) enhanced the killing of B. anthracis (anthrax) by macrophages in a time and ... of Valortim(R) in enhancing the killing of B. anthracis . We hypothesize that Valortim(R) may protect ... Valortim(R) enhances the immune response to B. anthracis infection." David P. Wright, President and ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium. The investigational antibody is designed to target a protein ... including: (1) lack of activity against the toxins produced by the B. anthracis bacteria, (2) need for long-term dosing to achieve full protection, ...

Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile

... targets the deadly toxins released within the human body by Bacillus anthracis that are the real culprits in most anthrax-related deaths. ABthrax is ... of anthrax. ABthrax is a human monoclonal antibody to Bacillus anthracis protective antigen that was discovered and developed by HGS, using ...

New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies

... way to address the anthrax threat. While antibiotics can kill the Bacillis anthracis bacteria, they are not effective against the deadly toxins that the ... strains of anthrax. ABthrax is a human monoclonal antibody to Bacillus anthracis protective antigen that was discovered and developed by HGS, using ...

Human Genome Sciences Submits Biologics License Application to FDA for ABthrax(TM)

... the U.S. Government upon FDA licensure of raxibacumab. About Anthrax Anthrax infection is caused by a spore-forming bacterium, Bacillus anthracis , which multiplies in the body and produces lethal toxins. Most anthrax fatalities are caused by the irreversible effects of the anthrax toxins. ...

Elusys' Anthrax Anti-Toxin, Anthim(TM), Enters Second Phase I Clinical Study

... Anthim Background Anthim is a high-affinity, humanized and deimmunized monoclonal antibody that targets the protective antigen of B. anthracis and neutralizes the lethal effects of anthrax toxins. It is being developed for prevention and treatment of inhalation anthrax. Anthim has been ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... is a fully human antibody designed to protect against inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium. The investigational antibody is designed to target a protein component known as the anthrax protective antigen of the lethal toxin complex ...

Anthrax Monoclonal Antibody Valortim Demonstrates Therapeutic Effect in New Primate Model of Established Anthrax Infection

... in humans exposed to aerosolized Bacillus anthracis spores. B. anthracis is the bacterium responsible for anthrax ... antigen is one of the toxins produced by B. anthracis and its presence in the blood is being evaluated ...

Anthrax Monoclonal Antibody Valortim(tm) Demonstrates Therapeutic Effect in New Primate Model of Established Anthrax Infection

... in humans exposed to aerosolized Bacillus anthracis spores. B. anthracis is the bacterium responsible for anthrax ... antigen is one of the toxins produced by B. anthracis and its presence in the blood is being evaluated ...
anthracis in Medical Dictionary

Anthrax

... to the spores of the bacteria Bacillus anthracis that become entrenched in the host body and ... East. ANTHRAX - Infection with Bacillus anthracis transmitted from infected or wild animals by ... Anthrax is caused by the bacterium Bacillus anthracis . While anthrax commonly affects hoofed animals ...

Bacillus anthracis

... Bacillus anthracis : The bacterium that causes anthrax . Anthrax ... (dormant) state called spores . Bacillus anthracis Bacitracin Overdose Bacitracin Zinc Overdose ... ) ... ANTHRAX - Infection with Bacillus anthracis transmitted from infected or wild animals by ...

Host

... is syphilis , which may reside in its host for 30 to 50 years. Anthrax is caused by exposure to the spores of the bacteria Bacillus anthracis that become entrenched in the host body and produce lethal poison s. It is primarily a disease of grazing animals such as cattle, sheep, goats, ...

Inhalation anthrax

... Definition: Inhalation or respiratory anthrax is an infectious disease caused by breathing in the spores of the bacteria Bacillus anthracis . Inhalation Anthrax Inhaled anthrax is particularly deadly. Although the spores are dormant when breathed in, they germinate when exposed ...

Spores

... nose. heart The hollow, muscular organ responsible for pumping blood through the circulatory system. ANTHRAX - Infection with Bacillus anthracis transmitted from infected or wild animals by contact with hides or by the ingestion or inhalation of spores . Symptoms: malaise and painless , ...

Toxin

... Toxin , anthrax : The toxic substance secreted by the bacterium Bacillus anthracis , the causative agent of the disease anthrax . Afla toxin Definition: Afla toxin s are toxin s produced by a mold that grows in nuts, ...

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anthracis in Biological News

Scripps research scientists identify blood component that turns bacteria virulent

... the key chemical that signals Bacillus anthracis , the bacterium that causes anthrax, to become ... in cells, as providing the signal for Bacillus anthracis to unleash virulence factors. Without the ... carbon dioxide, that signals the gram-positive B. anthracis to become virulent. This finding also is ...

NIST, Army researchers pave the way for anthrax spore standards

... and stability of laboratory-grade Bacillus anthracis spores under different storage conditions. Bacillus anthracis (Sterne), a harmless vaccine strain, was used in ... techniques to quantify the Bacillus anthracis concentrations: counting spores under a ...

New technique used to profile anthrax genome

... we can see in a much more detailed way how each of the 5,000+ genes in B. anthracis genome is expressed and regulated." The RNA-Seq approach works by using ... Bergman and colleagues sequenced mRNA samples that were collected from B. anthracis cells growing in a variety of conditions. They collected more than 270 ...

FBI unveils science of anthrax investigation

... killed. Sandia's work demonstrated to the FBI that the form of bacillus anthracis contained in those letters was not a weaponized form, a form of the ... prepared, which made examination initially difficult. When bacillus anthracis spores are weaponized, the spores are coated with silica nanoparticles ...

Tests show LLNL detection instrument can monitor the air for all major terrorist threat substances

... terrorists might use -- spores of a non-pathogenic strain of Bacillus anthracis (other strains of this bacteria cause anthrax); diethyl phthalate (a nerve ... of natural cobalt powder and RDX, and a non-pathogenic strain of Bacillus anthracis and RDX. In field experiments, SPAMS has been tested at San Francisco ...

Anthrax cellular entry point uncovered

... receptor, and use this entry point to boost its lethality. Bacillus anthracis infection occurs in three forms: cutaneous (skin), inhalation and through ... receptors, this discovery points toward a precise entry point which B. anthracis uses to proliferate and trigger lethal consequences, said Claudia Oliva, ...

American Society for Microbiology honors James W. Snyder

... other professional groups in the LRN. The 2001 anthrax attack was diagnosed by a clinical laboratory using the techniques outlined in the Bacillus anthracis Sentinel Protocol. Dr. Snyder received his Ph.D. from the University of Dayton. He is a Fellow of the American Academy of Microbiology and a ...

Anthrax attack posed greater potential threat than thought

... to have had anthrax, and 12 with no known B. anthracis exposure. The results: Immune responses ... the incidence of both subclinical and clinical B. anthracis infection. In an accompanying editorial, ... data suggest that cell-mediated responses in B. anthracis infection may be more sensitive than antibody ...

'Mad cow' proteins successfully detected in blood

... growth, you can see clear zones where the B. anthracis cells have been destroyed--whereas other ... for an FDA accepted method for identifying B. anthracis in clinical specimens. In 2002, FDA's Division of ... Devices agreed to recognize tests for B. anthracis as eligible for classification with a 510(k) ...

Anthrax test, developed by army and CDC, receives FDA approval

... growth, you can see clear zones where the B. anthracis cells have been destroyed--whereas other ... for an FDA accepted method for identifying B. anthracis in clinical specimens. In 2002, FDA's Division of ... Devices agreed to recognize tests for B. anthracis as eligible for classification with a 510(k) ...

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anthracis in Biological Technology

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

... form of illness in humans caused by the Bacillus anthracis bacterium. The investigational antibody is ... caused by the spore-forming bacterium Bacillus anthracis . Anthrax most commonly occurs in hoofed mammals ... activity against the toxins produced by the B. anthracis bacteria, (2) need for long-term dosing to ...

Taming the anthrax threat

... stop the bug in its tracks. Bacillus anthracis can quickly transform from a dormant spore (the ... it gets inside the warm lungs of a host. Bacillus anthracis can cause infection elsewhere in the body, but is ... When they infected mouse cells with a Bacillus anthracis strain altered to lack the gene, they found the ...

Anthrax vaccine produces immunity with nanoparticles, not needles

... and a recombinant protein of Bacillus anthracis to make the vaccine, which they gave first to ... of 1,000 times the lethal dose of Bacillus anthracis spores. All the animals survived, whereas none of ... the researchers delivered large doses of Bacillus anthracis spores directly into the animals nasal tissue, ...

Taming the anthrax threat

... stop the bug in its tracks. Bacillus anthracis can quickly transform from a dormant spore (the ... it gets inside the warm lungs of a host. Bacillus anthracis can cause infection elsewhere in the body, but is ... When they infected mouse cells with a Bacillus anthracis strain altered to lack the gene, they found the ...

Anthrax vaccine produces immunity with nanoparticles, not needles

... and a recombinant protein of Bacillus anthracis to make the vaccine, which they gave first to ... of 1,000 times the lethal dose of Bacillus anthracis spores. All the animals survived, whereas none of ... the researchers delivered large doses of Bacillus anthracis spores directly into the animals nasal tissue, ...

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

... acute infectious disease caused by the spore-forming bacterium Bacillus anthracis . Anthrax most commonly occurs in hoofed mammals and can also infect ... including: (1) lack of activity against the toxins produced by the B. anthracis bacteria, (2) need for long-term dosing to achieve full protection, ...

FBI unveils science of anthrax investigation

... killed. Sandia's work demonstrated to the FBI that the form of bacillus anthracis contained in those letters was not a weaponized form, a form of the ... prepared, which made examination initially difficult. When bacillus anthracis spores are weaponized, the spores are coated with silica nanoparticles ...

FBI unveils science of anthrax investigation

... killed. Sandia's work demonstrated to the FBI that the form of bacillus anthracis contained in those letters was not a weaponized form, a form of the ... prepared, which made examination initially difficult. When bacillus anthracis spores are weaponized, the spores are coated with silica nanoparticles ...

Tests show LLNL detection instrument can monitor the air for all major terrorist threat substances

... terrorists might use -- spores of a non-pathogenic strain of Bacillus anthracis (other strains of this bacteria cause anthrax); diethyl phthalate (a nerve ... of natural cobalt powder and RDX, and a non-pathogenic strain of Bacillus anthracis and RDX. In field experiments, SPAMS has been tested at San Francisco ...

PharmAthene Reports Year-End 2007 Financial Results

... may possess the ability to enhance macrophage killing of Bacillus anthracis (anthrax) spores within macrophages, potentially blocking the ability ... course as would be expected in humans exposed to aerosolized Bacillus anthracis (anthrax) spores. The pilot study demonstrated 50% survival in ...
anthracis in Biological Products

Rabbit Anti-Bacillus anthracis (Anthrax) Spore Antigen Antibody, Unconjugated from HyTest Ltd.

Description: In Western blotting antibodies recognize 94 K protein band, which corresponds to S-layer ...
Company:HyTest Ltd.
anthracis in Biological Dictionary

Bacillus

... Bacillus (written with a capital ... Characteristically, Bacillus cultures are Gram-positive when young, but may ... Details of Bacillus anthracis biology, toxicity, and effect on the human immune ... Living in the soil are huge numbers of bacteria belonging to the genus Bacillus . ... ...

Bacilli

... to a taxonomic class of bacteria. It includes two orders, Bacillales and Lactobacillales, which contain several well-known pathogens like Bacillus anthracis . For rod-shaped bacteria in general, see Bacillus (shape) ... For the class, see Bacilli . ... Many Bacillus species are able to ...
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