Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells
... this year.Many cases of prostate cancer depend on androgens like testosterone fortumor growth and cancer cell proliferation, said Dr. Knudsen, thestudy’s senior author. A common treatment for prostate cancer includeslimiting testosterone synthesis. Patients with mutated androgenreceptors may not respond to th...Tendency to hair loss inherited from the mother
...kly. Both mechanisms can lead to the effect of the androgens becoming greater, which in turn brings about hair loss." The findings are also interesting for the aspect of how hair loss is inherited. The gene for the androgen receptor lies on the x chromosome. Men always inherit the x chromosome from their moth...Tamoxifen-like drug suggests new ways to selectively block estrogen
... hormones," Greene said. "We could create designer androgens for prostate cancer, or designer glucocorticoids to treat inflammation." Since "the primary regulator of cofactor recruitment is receptor conformation," added study co-author Donald McDonnell of Duke, findings such as this should lead to the emergen...Pain killer fights breast cancer by targeting key enzyme
...opausal women. Aromatase converts hormones called androgens into estrogens, such as the hormone estradiol. Estrogen is a powerful mitogen ?an agent that causes cells to divide, and too much estrogen can cause cells to divide too quickly. While many women with estrogen-dependent breast cancer take aromatase i...Macrophage signaling may affect hormone resistance in prostate tumors
...(UCSD) School of Medicine. Male hormones called androgens are essential for the physiological function and growth of the prostate gland, and anti-androgen treatment, which blocks the expression of androgen target genes, is widely used for the treatment of prostate cancer. Unfortunately, most patients eventu...Early puberty linked to nutrition
...iochemical mechanism takes place through which the androgens become in estrone and estradiol. This way obesity and estrogens constitute an explosive couple able to trigger dangerous pathologic mechanisms. The leptine is the hormone of the obesity secreted by the adipose tissue, the responsible of the acceler......number of androgen receptors in their scalps , and androgens may contribute to both atheroscelrosis - build-up of fatty deposits in the arteries - and thrombosis, a susceptibility to blood clots.Researchers also say that heart disease and baldness may be inherited together and they recommended that bald men sh...Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors
...ich high-grade cancers that were less dependent on androgens for their growth had a competitive advantage." According to doctors , "Finasteride does not seem to be an attractive agent for the chemoprevention of prostate cancer." However, they do not advocate discontinuation of the drug when used to treat uri...Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors
...ich high-grade cancers that were less dependent on androgens for their growth had a competitive advantage." According to doctors , "Finasteride does not seem to be an attractive agent for the chemoprevention of prostate cancer." However, they do not advocate discontinuation of the drug when used to treat uri......st cancer risk and the level of both estrogens and androgens and in the patients with estrogen and progesterone positive receptors, there were higher sex hormone levels. Thus researchers conclude that higher levels of sex hormones may be strongly associated with the risk of estrogen and progesterone positive b...