ROXRO Announces FDA Accepts for Review NDA for ROX-888 for the Management of Acute Moderate to Severe Pain
... expected to be the first non-narcotic
indicated for the management of acute moderate to ... need for both clinicians and
patients -- an analgesic
that provides potent, rapid-onset pain control ... treatment of moderate to severe
pain. The analgesic
efficacy of ketorolac is primarily associated ...
SCOLR Pharma, Inc. Announces Positive Top-Line Results From Pivotal Clinical Trial Evaluating Efficacy of Extended-Release Ibuprofen
... The first primary endpoint was to
efficacy for the 8-12 hour period after the ... Inc., in early 2009."
Ibuprofen is an analgesic
typically used for the treatment of pain,
fever ... as generically. Total global
OTC sales of the analgesic
market in which the 12-hour ibuprofen ...
Study Confirms Effectiveness of Magnetic Therapy in Pain Relief
... of Static Magnetic Field Parameters Improves analgesic
Effect in Mice published in Bioelectrocmagnetics ... design to be optimal and to have an analgesic
effect of greater than 80 percent.
... Academy of Science used mice to test the analgesic
effect with a variety of static magnetic fields. ...
Seven Clinical Presentations on Tapentadol Immediate Release for Acute Pain to Be Featured at 2008 American Pain Society Annual Meeting
... into nerve cells; these compounds
The following tapentadol ... of
Tapentadol Immediate Release, an analgesic
with Mu-opioid Receptor Agonism;
Primary investigator: David Upmalis, M.D.
Poster 222: analgesic
Efficacy of Tapentadol Immediate Release ...
Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine
... (Drug Liking) Effects
Potencies of Intranasal Ketamine and Intranasal ... Acute Pain Following Bunionectomy
Abusers Can Be Subtyped by Preferred Route of ... Efficacy of Tapentadol, a Novel, Centrally Active analgesic
with a Dual Mode of Action, in Animal Models of ...
King Pharmaceuticals and Acura Pharmaceuticals Enter Agreement to Develop and Commercialize Immediate Release Pain Medicines Utilizing Acura's Aversion(R) (Abuse-Deterrent) Technology
... encompassing a
potentially wide range of opioid analgesic
products utilizing Acura's
patented Aversion(R) ... of four immediate
release opioid analgesic
products, including ACUROX(TM) Tablets ... Acura said, "We believe King's
abuse- deterrent analgesic
brand product pipeline and neuroscience
Labopharm To Present Poster On Onset Of Analgesic Effect Of Once-Daily Tramadol At Congress Of The European Society Of Regional Anaesthesia And Pain Therapy
... - Article Discussing analgesic
Efficacy of Labopharm's Once-Daily Tramadol ... of clinical study MDT3-005, "A Comparison of the analgesic
of Tramadol Contramid OAD Versus Placebo ... parallel study designed to assess
efficacy and safety of Labopharm's once-daily ...
AcelRx Announces Perfect Performance of Handheld Component of ARX-01 Sufentanil NanoTab PCA System in a Phase 2 Study
... of the IV delivery mode poses infection risk as well as predisposition to analgesic
gaps due to infiltrated and dislodged IV catheters. Additionally, the ... index opioid approved for IV and epidural administration. Although the analgesic
efficacy of sufentanil has been well established, its use has been limited ...
Echo Therapeutics Licenses Needle-Free Prelude SkinPrep System to Ferndale Pharma for Enhanced Delivery of Topical Lidocaine
... line of proprietary cosmeceutical products. Ferndale's LMX 4 topical analgesic
cream uses advanced formulation know how that significantly enhances ... leading brand in its class and is widely recognized for its fast onset of analgesic
action, wide margin of safety and superior ease of use.
'Pain in the ICU' report suggests comprehensive approach
... speaking may be able to point or blink when referring to a pain scale.
TrialTo verify the presence of pain, the ICU team can administer a low dose of first-line analgesic
followed by observation of the patient's pain-related behaviors.
Analgesic in Medical Technology
King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use
... and EMBEDA(TM) (ALO-01), two novel opioid analgesic
formulations that are in development, at the 71st ... to severe pain. A Phase III study evaluated the analgesic
efficacy and safety of ACUROX(R) in adults with ... containing oxycodone HCl as its sole active analgesic
ingredient with a proposed indication for the ...
Fast-Acting, Long-Lasting Topical Relief From Arthritis Pain
... get fast relief from arthritis pain is the use of analgesic
creams. The only problem is that the relief tends ... their soothing, medicated and clinically tested analgesic
Arthri-Zen Relief Cream (R). A recent ... part was that the relief lasted. Unlike other analgesic
creams on the market, Arthri-Zen Relief Cream(R) ...
Premier Research Announces Milestone New Drug Application
... containing oxycodone HCl as its sole active analgesic
ingredient, has a proposed indication for the ... and growing expertise of the company in the analgesic
therapeutic area. James Ottinger, Vice President ... significant value to companies working in the analgesic
About Premier Research
Cara Therapeutics Initiates Phase II Proof-Of-Concept Trial of Novel Analgesic in Acute Post-Operative Pain
... in the United States and will evaluate the analgesic
efficacy and safety of intravenous CR845 during ... produced plasma levels of drug associated with analgesic
efficacy in multiple preclinical studies.
In ... neuropathic and visceral origin and exhibited analgesic
efficacy for up to 18 hours after a single ....
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Total Knee Arthroplasty Presented at International College of Surgeons World Congress
... New Sustained-Release analgesic
Significantly Reduces Postop Pain, Opioid Use, ... or TKA, showed that the novel, sustained-release analgesic
effectively and safely controlled ... delivery of bupivacaine, a well-characterized analgesic
with a long-established efficacy and safety ...
Cara Therapeutics Announces Successful Completion of Phase I Clinical Trial of Novel Analgesic, CR845
CR845 expected to be associated with clinical analgesic
addition, CR845 infusion triggered a ... drug expected to be associated with clinical analgesic
The Company plans to advance its ... neuropathic and
visceral origin. The analgesic
and anti-inflammatory effects of CR845
lasted for ...
TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel
... it has initiated a
clinical trial to evaluate the analgesic
effect of NGX426, the oral prodrug
of its lead ... the time of onset, magnitude and duration of its analgesic
Specifically, the study will evaluate the ... the potential for NGX426 as a novel, oral analgesic
potential for tezampanel and NGX426 as ...
Acura and King Receive FDA Complete Response Letter Regarding Acurox(R)
... immediate release tablet containing oxycodone HCl as its sole active analgesic
ingredient with a proposed indication for the relief of moderate-to-severe ... developed Acurox(R) Tablets and are developing three additional opioid analgesic
product candidates utilizing Aversion(R) Technology pursuant to a 2007 ...
AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain
... of the IV delivery mode poses infection risk as well as predisposition to analgesic
gaps due to infiltrated and dislodged IV catheters. Additionally, the ... opioid approved for intravenous and epidural administration. Although the analgesic
efficacy of sufentanil has been well established, its use has been limited ...
New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal
... from the new Phase 3 study of tapentadol IR tablets, a prescription oral analgesic
approved by the U.S. Food and Drug Administration (FDA) in November 2008, ... it shows that patients treated with tapentadol IR experienced effective analgesic
relief of moderate to severe acute pain with fewer incidences of nausea ...
Analgesic in Medical Products
Physician's Drug Handbook, 10th Ed
Features:... and new indications and an updated appendix on herbal medicines Other appendices include guidelines for use of selected antimicrobials, selected analgesic
combination products, topical drugs, cytochrome P-450 enzymes and common drug interactions, therapeutic drug monitoring, dialyzable drugs, and phone ...
Features:... High emission power
Acts effectively at depth
High guarantee of safety
Controlled release of energy
Observes the thermal relaxation time of tissues ...
Company:DEKA Research & Development Corp.
Analgesic in Medical Dictionary
Nephropathy (Painkillers and the Kidney s) An analgesic
(AN-ul-JEE-zik) is any medicine intended to relieve pain . analgesic
nephropathy Definition: ...
... key structure in the kidney composed of capillary blood vessels. analgesic
nephropathy is one type of toxic injury to the kidney . It is ... ) ... Interstitial nephritis is one of the lesion s associated with analgesic
nephropathy , and can also occur with allergic reaction to a drug ( ...
... hormone s. AFP ( Alpha fetoprotein ) A tumor marker. Alopecia The loss of hair , which may include all body hair as well as scalp hair . analgesic
Any drug that relieves pain . A serious illness (like a tumor of the ovary or adrenal glands ) or fever Medication such as cancer ...
... target rapidly dividing cells, including hair cells. Alopecia The loss of hair , which may include all body hair as well as scalp hair . analgesic
Any drug that relieves pain . Aspirin and acetaminophen are mild analgesics. BALDNESS and HAIR LOSS ( Alopecia ) SYMPTOMS"It is hair on ...
... hand . AFP ( Alpha fetoprotein ) A tumor marker. Alopecia The loss of hair , which may include all body hair as well as scalp hair . analgesic
Any drug that relieves pain . Aspirin and acetaminophen are mild analgesics. Hemoglobin is normally composed of four building blocks, two ...
... pregnancy . AFP ( Alpha fetoprotein ) A tumor marker. Alopecia The loss of hair , which may include all body hair as well as scalp hair . analgesic
Any drug that relieves pain . Aspirin and acetaminophen are mild analgesics. Reticulocyte count Ferritin Alpha fetoprotein Treatment : ...
... or other stimulants . Psycho stimulants Psycho stimulants such as dextro amphetamine , methylphenidate, and modafinil may enhance the analgesic
effects of opioids.[159,160,180] They may also be used to diminish opioid-induced sedation when reducing the dose is not possible. Less frequent ...
... is torn. Source:MedicineNet Is cryptitis associated with colitis ? - Source:MedicineNet ... Anal Atresia ( Imperforate Anus ) Anal Fissure analgesic
Nephropathy Anaphylactic Reaction ( Anaphylaxis ) Anaphylactic Shock ( Anaphylaxis ) ... This includes people with colostomy or ile ostomy ...
... information, see AcuNav. Acidosis African Americans and Kidney Disease Fact Sheet Alport Syndrome Amyloidosis and Kidney Disease analgesic
Nephropathy : Painkillers and the Kidney s Anatomy of the Kidney s Anatomy of the Urinary System Anemia in Kidney Disease and Dialysis ......
... gland Journal of Medicine 344(February 15, 2000): 467-71. Other ... The main outcome measures were operative delivery rates, duration of labour, analgesic
requirements. perineal trauma and Apgar score s at 1 and 5 minutes. An abnormal evaluation immediately after birth (low Apgar score s). A ...
Analgesic in Biological News
How does the opioid system control pain, reward and addictive behavior?
The finding that morphines analgesic
and addictive properties are abolished in mice ... behaviors. The lack of mu-receptors abolishes the analgesic
effect of morphine, as well as place-preference ... Therefore, in addition to their potential analgesic
activity, delta-agonists may be useful in ...
Metastatic bone disease patients can walk in Lazarus' footsteps
... provided effective pain regression for individuals with both painful bone metastases and benign lytic lesions that didn't respond to conventional analgesic
Bones are the third most common location where cancer cells spread and metastasize. Bone metastases occur when cancer cells gain access ...
Study first to pinpoint why analgesic drugs may be less potent in females than in males
... at Georgia State University's Neuroscience Institute and Center for Behavioral Neuroscience are the first to identify the most likely reason analgesic
drug treatment is usually less potent in females than males. This discovery is a major step toward finding more effective treatments for females ...
Pain is in the eyes of the beholder
... mean that pain is any less real, they may lead to a new therapeutic approach for reducing pain. His team is now testing visual manipulations as an analgesic
strategy for use in clinical settings.
A new target for painkillers
... the "alpha9alpha10 nicotinic acetylcholine receptor."
"The numerous analgesic
compounds currently available are largely ineffective" for chronic nerve ... sciatica, with no adverse effects. Daily injections "produced a sustained analgesic
effect," the researchers wrote.
RgIA was such a potent pain reliever ...
Virtual realities against pain
... reduce the pain associated with medical treatment. The use of analgesic
was clinically revealing in most cases, especially in patients with very ... that ADTs are very useful as analgesic, and can reduce the amount of analgesic
administered. This new field of study can begin to move forward beyond its ...
Opiate cocktail may spare cells from morphine's dark side
... of drug tolerance, the requirement for increasing doses to maintain analgesic
effect, and the development of physical dependence. In the June 7 issue of ... Research Center and the University of California, San Francisco.
effects of morphine arise through the interaction of the drug with a ...
Old memory traces in brain may trigger chronic pain
... pain long after their injuries have actually healed"
The definitive answer -- and an effective treatment -- has long eluded scientists. Traditional analgesic
drugs, such as aspirin and morphine derivatives, haven’t worked very well.
A Northwestern University researcher has found a key source of ...
Detecting cold, feeling pain: Study reveals why menthol feels fresh
The methanol receptor, and other temperature receptors discovered in recent years by the Julius lab, offer potential targets for developing analgesic
drugs that act in the peripheral, nervous system, rather than centrally, where opiate receptors act, he says.
The finding is a milestone in an ...
Scripps research team sheds light on long-sought cold sensation gene
... TRPM8-deficient mice did not receive any acute pain relief from the cold plate suggesting that cold activation of TRPM8 can mediate some of the analgesic
effects of cold.
Just how the same sensation can be interpreted as unpleasant under certain circumstances and pleasant in others is still not ...
Analgesic in Biological Technology
QRxPharma Initiates Second Comparative Study for MoxDuo(TM) IR Dual-Opioid(TM) Pain Therapy
... a comparative 3-arm pilot study to evaluate the analgesic
efficacy and safety profile of MoxDuo(TM) IR ... of the study include: (1) comparing the analgesic
efficacy and safety profile of MoxDuo(TM) IR ...
MoxDuo(TM) IR is the first patented analgesic
product in the world that consists of two opioid ...
QRxPharma Initiates Comparative Phase 2 Proof-of-Concept Study for MoxDuo(TM) IV Pain Therapy
"QRxPharma's goal is to bring to market complementary analgesic
options for pain specialists, delivering greater patient tolerability and ... than morphine alone at equianalgesic doses and (2) whether the maximum analgesic
effect of MoxDuo(TM) IV is superior to morphine alone.
Anesiva Phase 3 Trial of Adlea Meets Primary Endpoint to Significantly Reduce Pain After Total Knee Replacement Surgery
... that the Phase 3
trial evaluating Adlea(TM), its long-acting, non-opioid analgesic
candidate, achieved its primary efficacy endpoint of reducing ... over the study duration.
"These compelling results confirm the analgesic
contribution of Adlea
during the most critical period following total knee ...
QRxPharma Initiates Comparative Study for MoxDuoIR(TM) Dual-Opioid(TM) Pain Therapy
... the efficacy and safety profile of MoxDuoIR(TM) against equivalent analgesic
doses of morphine and oxycodone alone for the treatment of acute moderate ... provide direct evidence of enhanced efficacy when compared to equivalent analgesic
doses of morphine and oxycodone alone," said Dr. John Holaday, Managing ...
Transdel Pharmaceuticals, Inc. Retains The Investor Relations Group
... tissue where the drug exerts its prolonged
localized anti-inflammatory and analgesic
effect. The Company is also
investigating other novel and generic drugs ... the target soft tissue and
exert its well-known anti-inflammatory and analgesic
effects. The Company
is also investigating other drug candidates and ...
Pharmos Corporation Reports 2008 Second Quarter Results
... the Company's NanoEmulsion delivery
technology for topical application of analgesic
agents commenced in June 2007 targeting 126 ... system, which is in
clinical-stage development for topical application of analgesic
Safe Harbor Statement
Statements made in ...
IntelliPharmaCeutics Announces Successful Completion of a Pilot Clinical Trial for its Abuse and Alcohol Resistant Sustained Release Oxycodone
... drug delivery technology. It is one of the Company's line
of in-house analgesic
products in development for the management of
moderate to severe chronic ... We will also
now apply the Rexista(TM) technology to other narcotic analgesic
our development pipeline."
OncoGenex reports lead drug candidate OGX-011 achieved primary endpoint in Phase 2 Trial with second-line chemotherapy for prostate cancer
... median survivals of approximately 10 months.
- Reduction in pain or analgesic
use was achieved in 50 percent or more of patients entering the study with pain: Reductions in pain or analgesic
use were seen in 50 percent of evaluable patients treated with ...
New Phase III Data Demonstrate Oxycodone / Naloxone Combination Tablet Reduces Opioid-Induced Bowel Dysfunction in Patients With Chronic Severe Pain
... the combination of
the opioid receptor agonist naloxone and the opioid analgesic
associated with a reduction in the impact of opioid-induced ... the impact of opioid-induced
constipation, while having no effect on the analgesic
efficacy of oxycodone
and minimal central effects. The oral PR oxycodone ...
Supelco(R) and MIP Technologies Launch New SPE Product for the Selective Extraction of NSAIDs From Environmental Water
... most highly consumed pharmaceuticals in the world."
Ibuprofen, diclofenac and naproxen are non-steroidal anti-inflammatory drugs that have analgesic
and antipyretic activities. Clofibric acid is an active metabolite of clofibrate, etofibrate and etofyllinclofibrate. These compounds are used as ...
Analgesic in Biological Definition
Drugs may be classified in many different ways, according to mechanism of action, effects, or even legal status.
Acetaminophen (also known as paracetamol, or under one of its trade names Tylenol), which can ...