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Amyloidosis in Medical News

Give the foie gras a miss

... poultry birds are known to undergo spontaneous amyloidosis due to a chronic inflammatory response that ... material in their organs. In laboratory tests amyloidosis is found to be accelerated by injection of tiny ... amyloid-affected beef, for instance, succumb to amyloidosis within weeks. Given ...

Neurochem moves eprodisate (KIACTA(TM)) drug development program forward for Amyloid A amyloidosis

... Phase II/III clinical trial in which 183 AA amyloidosis patients were enrolled at 27 sites around the world (Eprodisate for AA amyloidosis Trial, EFAAT). Patients who completed the ... A progressive and fatal condition, AA amyloidosis occurs in a proportion of patients with chronic ...

Neurochem reports results for fourth quarter and fiscal year 2007 and important advances on corporate objectives

... eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis is a complete, Class 2 response. The ... eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis in the European Union and Switzerland. In ... eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis in the European Union and concluded that another ...

Neurochem announces European opinion for Eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis

... for the treatment of Amyloid A (AA) amyloidosis and concluding that another study would be needed ... as we are acutely aware of the needs of AA amyloidosis patients who have no specific therapy presently ... eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis is a complete, Class 2 response. The ...

Neurochem announces eprodisate (KIACTA(TM)) receives acknowledgement of complete response and is granted Class 2 review

... (KIACTA(TM)) for the treatment of Amyloid A (AA) amyloidosis is a complete, Class 2 response. The ... Phase II/III clinical trial in which 183 AA amyloidosis patients were enrolled at 27 sites around the world (Eprodisate for AA amyloidosis Trial, EFAAT). Patients who completed the ...

Stem Cell Therapy Disappoints Against Rare Kidney Ailment

... Transplanted cells don't boost AL amyloidosis outcomes, study finds WEDNESDAY, ... of the New England Journal of Medicine . AL amyloidosis disease is one of several caused by abnormal ... called multiple myeloma. Survival with AL amyloidosis is typically measured in months. The average ...

Agent Orange Linked to Parkinson's, Heart Disease

... of an association between the herbicides and laryngeal cancer as well as cancers of the lung, bronchus, trachea and prostate, multiple myeloma, AL amyloidosis (a blood disorder) and type 2 diabetes. There was also "limited or suggestive evidence" between a parent's exposure to herbicides and spina bifida ...

Video: New Biological Therapy Ilaris(R) Approved in US to Treat Children and Adults with CAPS, a Serious Life-Long Auto-Inflammatory Disease

... birth or infancy, and occur daily throughout patients' lives. Long-term consequences may be serious and potentially fatal, and include deafness and amyloidosis resulting in renal failure and early death. Ilaris, previously known as ACZ885, is a fully human monoclonal antibody that rapidly and ...

ProteoTech to Present at 9th International Conference for Alzheimer's and Parkinson's Disease - Prague, Czech Republic, March 11-15, 2009

... as a nasal spray for the treatment of Alzheimer's disease. Lastly, ProteoTech is developing a novel small molecule compound for the treatment of amyloidosis associated with type 2 diabetes. For further information, please visit the Company's website at www.proteotech.com or contact us at ...

ProteoTech Receives Funding From The Michael J. Fox Foundation for Parkinson's Disease Research to Develop Tools for Imaging Alpha-Synuclein Aggregation in Living Parkinson's Brain

... as a nasal spray for the treatment of Alzheimer's disease. Lastly, ProteoTech is developing a novel small molecule compound for the treatment of amyloidosis associated with type 2 diabetes. For further information, please visit the Company's website at www.proteotech.com or contact us at ...
Amyloidosis in Medical Technology

ProteoTech's Exebryl-1(R) Enters Human Clinical Trials for the Treatment of Alzheimer's Disease

... as a nasal spray for the treatment of Alzheimer's disease. Lastly, ProteoTech is developing a novel small molecule compound for the treatment of amyloidosis associated with type 2 diabetes. For further information, go to http://www.proteotech.com or contact Steve Runnels, CEO at runnels@proteotech.com ....

Landmark Study Published in the New England Journal of Medicine Shows Important Benefits of Eprodisate (KIACTA) Treatment for Patients with Amyloid A (AA) Amyloidosis

... published the results of the "Eprodisate For AA amyloidosis Trial" (EFAAT), recognized as a landmark clinical ... Union and in Switzerland. About Amyloid A (AA) amyloidosis A progressive and potentially fatal condition, ... there is no approved therapy to treat AA amyloidosis and about half of all patients diagnosed with the ...

Velcade (bortezomib) for Injection Survival Data in Front-Line Multiple Myeloma Patients to be Featured at 11th International Myeloma Workshop

... and in combination with new agents such as HSP90-, AKT- and mTOR-inhibitors. Abstract highlights include: -- Treatment of Light Chain (AL) amyloidosis with the Combination of VELCADE and Dexamethasone * Lead investigator: Efstathios Kastritis, M.D., Alexandra Hospital, ...
Amyloidosis in Medical Definition

Proteopathy

... , Parkinson's disease , type 2 diabetes , amyloidosis , and a wide range of other disorders (see ... Hereditary cerebral hemorrhage with amyloidosis (Icelandic) (HCHWA-I) Cystatin C Familial amyloidotic neuropathy, Senile systemic amyloidosis Transthyretin AL (light ...

Pathology

... Aspartylglucosaminuria - Fucosidosis - Alpha-mannosidosis - Sialidosis Other Alpha 1-antitrypsin deficiency - Cystic fibrosis - amyloidosis ( Familial Mediterranean fever ) - Acatalasia v • d • e Pathology of the eye (primarily H00-H59 ) ...
Amyloidosis in Medical Dictionary

Amyloidosis

... amyloidosis and Kidney Disease On this page: Primary amyloidosis Dialysis -Related amyloidosis Hope Through Research For More Information ...

Anal abscess

... or peri anal abscess , or bleeding . amyloidosis - Cerebral (Senile Cerebral Amyloid Angiopathy) amyloidosis - Hereditary ( Hereditary amyloidosis ) Amyotrophic Lateral Sclerosis Anaerobic ...

Hereditary amyloidosis

... Hereditary amyloidosis Definition: amyloidosis is a type of disease in which an abnormal ... the involved organ . Familial or hereditary amyloidosis is the only inherited form of the disease . It ...

Primary amyloidosis

... Primary amyloidosis occurs when the body's antibody -producing ... antibody fragments. Some people with primary amyloidosis have a condition called multiple myeloma . Primary amyloidosis is usually treated with chemotherapy . The ...

Primary

... is more common in women than men. Primary amyloidosis occurs when the body's antibody -producing ... antibody fragments. Some people with primary amyloidosis have a condition called multiple myeloma . ... within 2 to 6 weeks. Primary systemic amyloidosis usually develops between the ages of 50 and 60. ...

Aplastic anemia

... of the bone marrow . Secondary Aplastic Anemia secondary Cardiac amyloidosis - AA Type ( Cardiac amyloidosis ) Secondary Glaucoma ( Glaucoma ) Secondary Hyperparathyroidism ...

Autosomal dominant

... PKD ) causes kidney failure in early childhood. Hereditary amyloidosis is though to be autosomal dominant , which means that only one copy of ... is necessary to cause the disease . A child of a parent with familial amyloidosis has a 50-50 chance of developing the disease . Symptoms can begin ...

Heart transplant

... may be considered for some patients (not in those with AL type amyloidosis , however, since their disease compromises many organ s). Patients ... This test may reveal the cause of a cardiomyopathy , myocarditis , amyloidosis , or a heart transplant ... Heart transplant Heart valve repair ...

Multiple myeloma

... , frequent urination , and broken bones . Some people with primary amyloidosis have a condition called multiple myeloma . The antibody fragments come ... heart disease or kidney failure , generally occurs within a few years. amyloidosis associated by multiple myeloma usually has a poor prognosis . A ...

Myeloma

... , chronic lymph ocytic leukemia , ... Some people with primary amyloidosis have a condition called multiple myeloma . The antibody fragments ... heart disease or kidney failure , generally occurs within a few years. amyloidosis associated by multiple myeloma usually has a poor prognosis . A ...

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Amyloidosis in Biological News

A novel way found to prevent protein plaques implicated in Alzheimer's

... and thus slowing, halting, or reversing disease progression, says Dr. Levy, who is also Director of the Laboratory of Molecular Pathology of Cerebral amyloidosis at the Nathan S. Kline Institute for Psychiatric Research in Orangeburg, New York. With support from the Alzheimers Association, Dr. Levys ...

Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging

... in a non-fibrillar form. Tramiprosate (Alzhemed? decreases by 38% (p-value Tramiprosate (Alzhemed? treatment in a transgenic mouse model of brain amyloidosis resulted in a dose-dependent reduction of over 60% of Aβ levels in plasma. There were significant decreases in brain levels of both soluble Aβ40 ...

New drug could reduce tissue damage after heart attack

... in the test tube, and blocks the tissue damaging effect of CRP in an experimental heart attack model. Professor Mark Pepys, of the UCL Centre for amyloidosis and Acute Phase Proteins, whose work on CRP has been supported by the Medical Research Council since 1979, says: "Although heart attacks are ...
Amyloidosis in Biological Technology

International Guidelines for First-Line use of Freelite(TM) in Diagnosis and Management of Multiple Myeloma to be Published in "Leukemia"

... quantitative monitoring of patients: - in AL amyloidosis patients, serial serum FLC measurements are more ... in other conditions including lymphoma, MGUS, amyloidosis and some inflammatory disorders. Source: ... . About AL amyloidosis ...
Amyloidosis in Biological Definition

Colchicine

... effect. Colchicine as medicine Colchicine is FDA -approved for the treatment of gout and also for familial Mediterranean fever , amyloidosis , and scleroderma . Side-effects include gastro-intestinal upset and neutropenia . Starting the drug early during an attack of gout can exacerbate ...
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