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Aldosterone in Medical News

Overweight male teens with normal blood pressures showing signs of heart damage

... in high school in Augusta, Ga., found the hormone aldosterone highest among the overweight males. Early ... we should be screening for and treating high aldosterone in obese males with normal pressures, ... to screen." This first evidence of elevated aldosterone levels and early heart damage in a pediatric ...

New target for heart failure therapy identified

... of the National Academy of Sciences , show that aldosterone production is mediated by a protein called ... when they are activated by angiotensin II. aldosterone is secreted by the adrenal cortex. Its levels are ... after myocardial infarction. The production of aldosterone was previously thought to be solely the result of ...

Hormone linked to high blood pressure and blood vessel disease in African-Americans

... have linked higher levels of the hormone aldosterone to high blood pressure and blood vessel disease in African Americans. aldosterone is secreted by the adrenal glands and causes salt ... "Previously, we found relatively high aldosterone levels in African Americans with high blood ...

New target for maintaining healthy blood pressure discovered

... Blood pressure was reduced in both types of genetically engineered mice relative to control littermates. The RAAS molecules renin, angiotensin I, and aldosterone were also reduced, a biological situation leading to lower blood pressure. The team found that the PG F2-alpha receptor is expressed in the ...

2009 DeLee Humanitarian Award goes to Marshall Lindheimer, M.D., of the University of Chicago

... in filtered sodium during pregnancy. With another University of Chicago colleague, Edward Ehrlich, Lindheimer elucidated the roles of the hormones aldosterone and progesterone in sodium and potassium regulation during pregnancy. Working with John Davison, of Newcastle upon Tyne University, England, ...

Study finds treatment fails to improve common form of heart failure

... at Wake Forest Baptist are collaborating in another ongoing trial called TOPCAT (Treatment of Preserved Cardiac function heart failure with an aldosterone anTagonist), testing another medication for treatment of this condition. The study is being funded by the National Institutes of Health. Patients ...

SAGE acquires 2 new medical journals

... Renin-Angiotensin-Aldosterone System is the official journal of the Renin Academy, dedicated to highlighting the importance of the Renin Angiotensin aldosterone System (RAAS) in circulatory control and hypertension. JRAAS is published quarterly. We are delighted by the acquisition of these two important ...

Fashion Guru Nina Garcia Launches National Design Competition

... serum potassium include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDs. Patients should be counseled that OCs do not protect against HIV infection and other sexually transmitted diseases. The ...

Certain Cholesterol Drugs Show Their Limits

... explained. "The drug also lowered LDL, but it did other things they were not anticipating." One of these unintended consequences was to raise aldosterone levels, a hormone that helps keep a balance between sodium and potassium levels. "Aldosterone is a byproduct of angiotensin [a chemical that causes ...
Aldosterone in Medical Technology

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... combination of the only approved drug, Tekturna, that works by directly targeting renin and decreasing the activity of the renin angiotensin aldosterone system (RAAS) and, HCTZ, a diuretic. This results in more significant blood pressure reductions, compared to taking either drug alone." ...

Study: Identical Doses of BiDil Components Are Not Bioequivalent to the Fixed Dose Combination-BiDil-Used in A-HeFT

... angiotensin converting enzyme inhibitor or an angiotensin II receptor blocker, and a beta blocker, and many also received a cardiac glycoside or an aldosterone antagonist. In A-HeFT, self-identified black patients taking BiDil in addition to current standard heart failure therapies (n=518) experienced a ...

Everest Data on Short- and Long-Term Use of Otsuka's Investigational Novel Treatment, Tolvaptan, Published in Journal of the American Medical Association and Featured in ACC's Late Breaking Clinical Trials

... physicians could choose conventional therapies for their patients, including diuretics, digoxin, ACE inhibitors, angiotensin II receptor blockers, aldosterone blockers, beta-blockers, nitrates, nesiritide and/or hydralazine.(1) "EVEREST adds to the collection of data on tolvaptan and its potential uses," ...
Aldosterone in Medical Products

Aldosterone RIA Test

Description:... aldosterone is produced in the adrenal cortex and is the most potent mineralocorticoid in humans. aldosterone secretion appears to be stimulated primarily ... angiotensin, with angiotensin II then stimulating aldosterone synthesis. Aldosterone stimulates renal ...
Company:Diagnostic Systems Laboratories, Inc.

Renin IRMA Test

Description:... system to cause vasoconstriction. In addition, angiotensin II stimulates aldosterone secretion from the adrenal gland, resulting in increased renal tubular ... patients with hypertension due to hyperaldosteronism, while both renin and aldosterone levels are elevated in patients with renovascular hypertension [2]. ...
Company:Diagnostic Systems Laboratories, Inc.

ACTH RIA Test

Description:... and secretion are directly inhibited by glucocorticoids [1,2]. ACTH stimulates adrenal steroidogenesis, mainly cortisol production, but also aldosterone and adrenal androgen synthesis. Decreased ACTH secretion can occur in a variety of pituitary and hypothalamic disorders and in certain systemic ...
Company:Diagnostic Systems Laboratories, Inc.

17a-OH Progesterone RIA Test

Description:... in androgen levels cause progressively severe virilization beginning during fetal life and infancy. In addition, 21-hydroxylase is required for aldosterone synthesis, and approximately 50% of cases of 21-hydroxylase deficiency suffer from potentially fatal salt-wasting. Elevated serum 17alpha-OH-P levels ...
Company:Diagnostic Systems Laboratories, Inc.

17a-OH Progesterone EIA Test

Description:... in androgen levels cause progressively severe virilization beginning during fetal life and infancy. In addition, 21-hydroxylase is required for aldosterone synthesis, and approximately 50% of cases of 21-hydroxylase deficiency suffer from potentially fatal salt-wasting. Elevated serum 17alpha-OH-P levels ...
Company:Diagnostic Systems Laboratories, Inc.

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Aldosterone in Medical Dictionary

Aldolase

... muscle turn sugar into energy. Aldolase aldosterone aldosterone - Urine (24-Hour Urinary aldosterone Excretion Rate) Alertness - Decreased ( ...

Aldosteronism

... aldosteronism : Overproduction of the hormone aldosterone from the outer portion (cortex) of the ad renal ... , your doctor may measure the levels of aldosterone and renin in your blood . Renin is an ... glands produce too much of the hormone aldosterone , which regulates fluids and salt in the body. ...

Aldosterone

... aldosterone is secreted in response to low salt levels. aldosterone then activates the MR (for mineralocorticoid receptor) gene . aldosterone levels may vary between men and women and are ...

Hyperaldosteronism

... : Overproduction of the hormone aldosterone from the outer portion (cortex) of the ad renal ... in the adrenal glands of the hormone aldosterone ( hyperaldosteronism ), by Cushing's syndrome , ... primary hyperaldosteronism will haveincreased aldosterone (for more information see the ...

Potassium

... are mainly controlled by the steroid hormone aldosterone . (For more information see the aldosterone test.) aldosterone is secreted from the ad renal gland when ...

Renin

... in the body [Top] ... Urinary casts Renin aldosterone Treatment : This version of the Encyclopedia ... ACE plays an important role in the renin / aldosterone mechanism which controls blood pressure by ... Hormone s that are usually decreased include aldosterone , renin , estrogen (in women), calcitonin , ...

Adrenal glands

... s. The ad renal cortex is the surface layer. It produces the hormone s aldosterone and cortisol . aldosterone regulates fluid and electrolyte balance. There are two adrenal glands ...

Glands

... s. The ad renal cortex is the surface layer. It produces the hormone s aldosterone and cortisol . aldosterone regulates fluid and electrolyte balance. A chemical made by glands ...

Renal

... s. The ad renal cortex is the surface layer. It produces the hormone s aldosterone and cortisol . aldosterone regulates fluid and electrolyte balance. Chronic renal failure ...

Alkalosis

... A clinical syndrome characterized by enlargement of certain kidney cells, alkalosis , hypokalemia , and increased production of the hormone aldosterone . Common in children and may be seen in dwarfism . Environmental Causes Incorrect Water Chemistry Acidosis or Alkalosis Osmotic Stress ...

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Aldosterone in Biological News

Understanding hypertension in African Americans proves elusive

... high is African Americans. Alterations in aldosterone regulation may play a role because aldosterone causes the kidney to retain salt. Brown said he ... In the study, he found that the level of aldosterone was related to how the two racial groups ...

Researchers' discovery may lead to hypertension treatment

... Prior to the discovery, researchers knew that a human steroid called aldosterone activates the kidney to reabsorb sodium and excrete potassium, which led ... rat's urine but kept potassium levels constant. Schroeder said that while aldosterone (which does the opposite) is a steroid hormone, this newly discovered ...

Evolution of 'irreducible complexity' explained

... experiments showed that the receptor had the capacity to be activated by aldosterone long before the hormone actually evolved. Thornton's group then ... it "preadapated" to be recruited into a new functional partnership when aldosterone later evolved. By recapitulating the evolution of the receptor's DNA ...
Aldosterone in Biological Definition

Hormone

... hormone (TSH) thyrotropin-releasing hormone (TRH) Steroid hormones : Glucocorticoids cortisol Mineralocorticoids aldosterone Sex steroids Androgens testosterone dehydroepiandrosterone (DHEA) dehydroepiandrosterone sulfate (DHEAS) androstenedione ...

Kidney

... 7.4. Urine, on the other hand, becomes either acidic at pH 5 or alkaline at pH 8. Sodium ions are controlled in a homeostatic process involving aldosterone which increases sodium ion absorption in the convoluted tubule. Any rise or drop in blood osmotic pressure due to a lack or excess of water is ...

Nephron

... as glucose , amino acids , phosphates , and so on) according to the body's needs under hormonal control , or from anti-diuretic hormones , aldosterone , parathyroid hormone , atrial-natriuretic peptide and others. In this process urine is produced, and in doing so, eliminates wastes from the ...

Osmoregulation

... osmoregulation. Kidneys regulate the amount of water in urine waste. With the help of naturally producing hormones such as antidiuretic hormone , aldosterone , and angiotensin II , the human body can increase permeability of the collecting ducts in the kidney to reabsorb water and prevent it from being ...
Aldosterone in Biological Dictionary

Collecting tubules

... nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone ... collecting tubule ( kə′lektiŋ ′tü′byül ) ( anatomy ) One of the ducts conveying urine from the renal tubules (nephrons) to the ...
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