Viral DNA sequence a possible trigger for breast cancer
...the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into canc... other cancer-causing viruses such as Epstein Barr virus and Kaposi's sarcoma virus, but what role this sequence plays in cancer development has remained une...Association of herpesvirus with lung disorder questioned
...rnal of Medicine that reported the presence of the virus in similar samples of lung tissue from a similar number of patients. Both primary pulmonary hypertension and infection with HHV-8 are uncommon, Katano and co-authors explained. Human herpesvirus 8 infection is associated with Kaposi's sarcoma, a t...Columbia research lifts major hurdle to gene therapy for cancer
...corporating it into a specially designedvirus. The virus eradicated prostate cancer cells in the lab and in...ma), skin(melanoma) and colon cancer - because the virus is constructed toexploit a characteristic of all solid cancers."What's exciting is we may now be abl...Topical treatment shown to inhibit HIV and herpes simplex virus infection
...es protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was funded by the ...The DNA tumor virus simian virus 40 produces the Large T antigen which inactivates two of the cell's most important cancer-preventing...GenomONE-Neo EX HVJ-E 4 vial(s) Transfection Reagents from Cosmo Bio Co., Ltd.
HVJ (hemagglutinating virus of Japan, also named Sendai virus) Envelope VECTOR KIT is a tool for transfection of molecules by means of membrane fusion. Most efficient transfection are for siRNA (RNAi), Protein, Oligo, cDNA, Antibodies, Vector, and Biomolecule in vitro and in v...Interferon Antibody Bioassays Services from PBL InterferonSource
...amma. The assay system, specifically the cell and virus types, varies depending on the derived species of interferon to be analyzed....Mouse Anti-RFC1 Monoclonal Antibody, Unconjugated, 1320 from GeneTex
...inated synthesis of both DNA strands during simian virus 40 DNA replication in vitro. It consists of five different subunits known as p140, p40, p38, p37, and p36. RFC is a DNA-dependent ATPase that binds in a structure-specific manner to the 3-prime end of a primer hybridized to a template DNA, an activit...Viruses microRNA Microarray from LC Sciences
...The Viruses microRNA Microarray contains all known virus microRNAs (98 unique mature sequences). The comprehensive probe content is based on the latest version of the Sanger miRBase sequence database (Release 8.2, July 06). Add up to 100 custom sequences at no extra charge. Paraflo Technology These are ...Topoisomerase I from vaccinia virus is a type I eukaryotic topoisomerase that removes both positive and negative superhelical turns (also called right- and left-handed supercoils) from covalently closed DNA. The product of the reaction is a covalently closed, circular DNA with fewer po...New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
...antly more potent thanthat derived from the herpes virus VP16 protein. 10 In addition,whereas overexpression of transcription factors containing the activation domainfrom VP16 can be toxic, 11 overexpression of the activation domainfrom NF- k B p65 has not been reported to be toxic. 10,12 It was ......E1gene is essential for the assembly of infectious virus particles and iscomplemented in vivo by an adenovi...ispensable. Notonly do these deletions prevent the virus from replicating itself, they alsocreate space for up to 7.5 kb of foreign DNA. 1 Two methods have...Brilliant Core Reagent Kits for QPCR and QRT-PCR
... is a genetically modified Moloney murine leukemia virus reversetranscriptase with a point mutation that results in removal of RNase H activity.In numerous tests, StrataScript reverse transcriptase has produced high yieldsof cDNA and long transcripts, providing ideal cDNA templates for subsequent PCRamplif...Versatile Vectors for Ponasterone A- Inducible Control of Gene Expression in Mammalian Cells
...ntry site (IRES) from encephalomyocarditis virus (EMCV) upstream of the second (RXR) open reading frame (ORF), which allows high-level internal (cap-independent) initiation of translation of ORFs positioned downstream in an appropriate context. 4 Expressing both recept......s and transelements required to produce infectious virus are separated onto three plasmids,the probability of producing undesired replication-competent virus is very low.The range of target cells to be infected is determined by which one of fouravailable env...Virus Level could Predict Cervical Cancer Risk
...cervical cells. Two strains of the human papilloma virus (HPV) are associated with an increased chance of g...ish researchers say that measuring the levels of a virus linked to cervical cancer could help to identify women at risk from the disease long before it devel...Kissing can cause Kaposi’s Sarcoma in AID
...sssing may be responsible for a form of the herpes virus that causes an AIDS-related skin cancer called Kap...tches and can also attack the internal organs. The virus rarely causes sickness among people with normal disease defenses but attacks those with weakened imm...Ebola Virus - 'Outbreak' Claims More Lives In Uganda.
The curse of Uganda – the deadly Ebola virus in its latest outbreak has claimed around 156 lives by December 5th according to Health Ministry officials in Kampala. More shocking is the fact that the dead include many health workers including doctors & nurses. But what shocked the nation was t...Sperm washing helps couples – Breakthrough in focu
...course carries a 1 in 500 risk of transmitting the virus to the female partner and through her to the fetus... option in which infected sperm are washed free of virus before insemination into the female partner at the time of ovulation. Absence of detectable HIV is v......ch in tackling the virus. The idea is to block the virus from growing inside the body rather than trying to bolster the immune system against the virus as many vaccines try to do. TAT protein is an important protein in the virus, which is a key build...OraSure HIV-1 Oral Specimen Collection Device
...und in saliva. If present, antibodies to the HIV-1 virus will be collected in this sample. The pad is then...ry test for antibodies to the HIV-1 virus, not the virus itself. This is why OraSure HIV-1 can test for HIV-1, but the virus is not known to be transmittable......ome of the mutations have been shown to render the virus resistant to the action of these drugs, diminishing the effectiveness of the treatment.The detection of mutations in HIV-1 that correlate with drug resistance provides useful information to physicians in monitoring the course of treatment and selecti......ial diagnosis of acute influenza type A and type B virus infection....... viral replication by promoting the release of the virus from infected cells. The ZstatFlu substrate is labeled with a chromagen. When influenza virus is present, the viral neuraminidase enzyme cleaves the ZstatFlu substrate, which liberates the chrom...Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies
The Epstein Barr virus (EBV), which causes infectious mononucleosis (IM), is one of the most common human viruses. EBV occurs worldwide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95 percent of adults between 35 a...Fast, Accurate Influenza A/B Antigen Detection
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...ed to detect the presence of the influenza A and B virus in a patient nasal wash or nasal swab sample withi...rinciple of antibody specificity for the influenza virus nucleoprotein (NP) to selectively interact with the influenza A and B viruses. The NP is evolutionar...West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak
...tributing Editor The first human case of West Nile virus (WNV) for 2005 was reported to have occurred in Ka...ther vertebrates serving as incidental hosts. The virus was first isolated from a febrile patient in the West Nile region of Uganda in 1937. It remained a ......es on surveillance, diagnosis, and treatment. The virus in question is the H5N1 subtype of influenza A, wh...) studies. Since it remains unclear how much H5N1 virus humans shed, different types of respiratory samples (nasal or throat swabs, washes, or aspirates) sh...