It's not all genetic: Common epigenetic problem doubles cancer risk in mice
... have already noted an association between loss of imprinting of IGF2 and colon cancer in people, the current ex...ents were designed to find out whether the loss of imprinting is involved in cancer's development or just in its progression. "Most researchers, including me, ex...How IVF could be causing genetic errors in embryos
...onday) that preliminary work investigating genetic imprinting in mouse embryos had shown that certain culture me...nd why these techniques appear to be affecting the imprinting of these genes. We hope this understanding will enable the scientific community to make better cultu...Non-coding RNAs help silence the mammalian transcription
...cnq1ot1. "As we explore the mechanism of genomic imprinting in greater detail, it is becoming clear that there...hanisms lends further support to the argument that imprinting arose gradually over a long period in mammals, not all at once," explains Dr. Tilghman. ...Zebra finch males prefer females with exaggerated maternal traits
...unfamiliar one, it has generally been assumed that imprinting itself could not give rise to preferences for nove...nt stimuli, but the presence of this effect in the imprinting process has not been demonstrated previously. The outcome of the study shows that the skewed mating ...... “But some genes ?through a process called genomic imprinting ?only use one parent’s copy; the spare copy from t...is silenced by a chemical stamp.? The concept of imprinting has long puzzled scientists as it appears to undermine the natural benefits organisms gain from inhe...High-Protein Diet Found To Reduce Fertility
...isting of 25 percent protein disrupted normal gene imprinting patterns in mice embryos at an early stage in their development. Some mice were fed a diet containing 25 percent protein. The control group was fed 14 percent protein. The mice were then mated. Embryos from females on the high-protein diet developed ...Mothers’ diet during pregnancy may cause child obesit
...pens it is like a vicious circle where a mother is imprinting her baby with a faulty metabolism which is passed on in the genes and just keeps on being passed on." It would certainly do a world of good if nutrition issues are addressed at the school level itself, so that children can form healthy dietary hab...'single–parent' stem cells to replace adult mice organ
...ing," McLaughlin said. "It turns out that genomic imprinting may be more a concern for developing stages and not so much a factor in the routine function of adult tissue, which was the ultimate goal for deriving these stem cells." To study uniparental stem cells and the possible effects of genomic imprinting...New Hope for Regenerative Medicine
...e parental origin. Uniparental cells only have the imprinting marks for one parental type (or "from one parent") with unknown consequences if harvested and transplanted into adults. Previous work has shown that uniparental ES cells have only limited ability to contribute to fetal and postnatal development in......e. It adds to growing theories that suggest sexual imprinting is an active process which involves the relationship between the child and the adult upon whom they imprint. This reveals the importance of parental relationships in partner selection, which could move studies in areas like evolutionary biology, f...