Urine in Medical Technology

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

... - Significant peak urine flow (Qmax) improvements within 2-6 hours of the ... by urination problems, including decreased urine flow, more frequent urination and nocturia. ... with signs and symptoms of BPH, including a peak urine flow rate (Qmax) between 4 and 15 mL/sec (mean of ...

Watson Announces United States Availability of RAPAFLO(TM) (silodosin), a Novel New Treatment in Benign Prostatic Hyperplasia (BPH)

... RAPAFLO(TM) was proven to rapidly increase urine flow in just two to six hours following the ... in these tissues to relax, resulting in improved urine flow and a reduction in BPH symptoms. The ... to significantly improve Qmax scores (maximum urine flow rates) as early as two hours following first ...

PLC Systems Defers Pivotal Study of RenalGuard(TM) in the U.S.

... provides an automated method of measuring urine outputs and then matching these outputs ... be reduced. RenalGuard facilitates this increased urine clearance enabling the body to more rapidly void ... procedures where creating and maintaining high urine outputs is deemed beneficial to patients. ...

PLC Systems Receives FDA Approval to Commence Pivotal Study Of RenalGuard(TM) In the U.S.

... suggests that initiating and maintaining high urine output during imaging procedures allows the body ... the theory that creating and maintaining a high urine output is beneficial to patients undergoing ... System is intended to ensure that a high urine flow is maintained before, during and after these ...

Mayo Clinic Proceedings January Tip Sheet

... has become widespread during the past decade. urine drug screens have been the most common method for ... up-to-date information about proper evaluation of urine drug screens. The authors also examine the ... antidepressants) and they discuss how to evaluate urine drug screens for adulterations, substitutions and ...

PLC Medical Systems Names Lead Investigators for Pivotal Trial to Evaluate RenalGuard System(TM) and RenalGuard Therapy(TM)

... that initiating and maintaining high urine output during imaging procedures allows the body ... the theory that creating and maintaining a high urine output is beneficial to patients undergoing ... System is intended to ensure that a high urine flow is maintained before, during and after these ...

Xenomics Announces Issuance of a US Patent That Covers Use of Transrenal Nucleic Acid Technology for Infectious Disease Diagnostics and Monitoring

... body that cross the kidney barrier from blood to urine and can be used for genetic analysis. Xenomics' ... testing. Xenomics' scientists have detected in urine DNA and RNA fragments of different pathogens, ... technology uses safe and simple urine collection and can be applied to a broad range of ...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... with T2DM with normoalbuminuria (less than or equal to 35 mg albumin/g urine creatinine for women and less than or equal to 25 mg albumin/g urine creatinine for men) at the outset, and who have at least one additional ...

Investigational Genetic Test May Help Address Common Problems in Prostate Cancer Diagnosis

... - Eight Studies Presented at Leading Urology Meeting Show that Simple urine Test for PCA3 Gene May Improve Accuracy of Prostate Cancer Detection, ... John Ward, et al. (4) AUA poster #1814, "Feasibility of the PCA3 urine test in a community- based screening setting." Adrie van Bokhoven, et ...

Researchers Discover Metabolite Linked to Aggressive Prostate Cancer

... looked at 1,126 metabolites across 262 samples of tissue, blood or urine associated with benign prostate tissue, early stage prostate cancer and ... was detected in the urine, which has researchers hopeful that a simple urine test could be used. In addition, the researchers found that ...

Light Sciences Oncology Begins Clinical Trials of Litx Therapy in Patients with Enlarged Prostate

... and frequent urination caused by the enlarged prostate's reduction of urine flow through the urethra. Early stage treatment is critical, because ... is designed to effectively re-establish and maintain an unobstructed urine flow, relieving BPH symptoms. ABOUT LIGHT SCIENCES ONCOLOGY Light ...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

... on existing study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate ... RenalGuard is based on the theory that creating and maintaining a high urine output is beneficial to patients undergoing imaging procedures where ...

PLC Systems Reports Fourth Quarter 2007 Results

... This therapy is based on the theory that creating and maintaining a high urine output is beneficial to patients undergoing imaging procedures where ... design of the RenalGuard System is intended to ensure that a high urine flow is maintained before, during and after these procedures. This should ...

Watson Announces Silodosin NDA Accepted for Filing by FDA for the Treatment of Benign Prostatic Hyperplasia

... the primary endpoint. Secondary endpoints included improvements of maximum urine flow and quality of life. As expected, the most common side effects seen ... these receptors relaxes the smooth muscles, resulting in an improvement in urine flow and a reduction in BPH symptoms. The selective binding of silodosin ...

Help! I'm Sick. How Do I Handle My Diabetes?

... have been instructed by your health care team, check for ketones in your urine every few hours. -- Don't stop insulin or medications - Unless your ... provider if there is a rise in ketones or if there are ketones in your urine for more than 12 hours; if you are vomiting or have diarrhea for more than ...

PLC Systems Achieves Successful Early Conclusion of RenalGuard(TM) Pilot Safety Trial

... This therapy is based on the theory that creating and maintaining a high urine output is beneficial to patients undergoing imaging procedures where ... design of the RenalGuard System is intended to ensure that a high urine flow is maintained before, during and after these procedures. This should ...

Study Shows VAPRISOL(R) is Effective in Increasing Serum Sodium Levels and Well-Tolerated in Patients With Euvolemic or Hypervolemic Hyponatremia

... blocks both V1a and V2 vasopressin receptors, resulting in increased urine output without increased sodium loss. This effect, known as "aquaresis," ... is a novel drug that blocks the activity of AVP, resulting in increased urine output without loss of valuable electrolytes such as sodium and potassium. ...

Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia

... blocks both V1a and V2 vasopressin receptors, resulting in increased urine output without increased sodium loss. This effect, known as "aquaresis," ... is a novel drug that blocks the activity of AVP, resulting in increased urine output without loss of valuable electrolytes such as sodium and potassium. ...

DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux

... of patients. VUR, a malformation of the ureter that causes a backflow of urine from the bladder toward the kidneys, is the most common abnormality of the ... one percent of all children born suffer from VUR, which causes urine to flow backwards from the bladder to the kidneys through one or both of ...

Cryo-Cell Announces C'elle(SM) Research and Development Collaboration with Cryopraxis Cryobiology Ltd.

... cells to develop potential therapies for female stress urinary incontinence, a condition primarily caused by a deficiency in the muscles that affect urine flow. Since stem cells isolated from menstrual fluid have the ability to contract, research will determine whether injecting the cells into the ...

R-Tech Ueno, Ltd. Completes Phase 1 Clinical Study on RK-023

... region in order to investigate the safety in the entire body and scalp. No serious adverse event occurred. After application of the drug, blood and urine were collected in the lapse of time to determine drug concentrations. However, the drug concentration was below the quantification limit at any of ...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... Do not take TEKTURNA or TEKTURNA HCT if you are allergic to any of its ingredients. Do not take TEKTURNA HCT if you have a history of reduced urine output, or if you have allergic reactions to certain drugs known as sulfonamides. If you are taking TEKTURNA or TEKTURNA HCT, tell your doctor about ...

Vantia Therapeutics' Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia

... was successful in producing a predictable and sustained anti-diuretic effect in patients, as determined by increased osmolality and decreased urine output. The study also found that VA106483 was generally well tolerated among the patient population. Nocturia (defined as waking frequently ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... and tolerability, kidney GL-3 as measured in urine, and an assessment of renal function (including glomerular filtration rate (GFR) and 24-hour urine protein). Additionally, the FDA and Amicus reached agreement on an improved methodology for the histological evaluation of GL-3 in the kidney ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... feel very tired skin or eyes look yellow little or no appetite vomiting muscle aches dark urine clay-colored bowel movements fevers chills stomach discomfort skin rash If you take ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... feel very tired skin or eyes look yellow little or no appetite vomiting muscle aches dark urine clay-colored bowel movements fevers chills stomach discomfort skin rash If you take ...

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

... in kidney levels of SGLT2 with >75% reduction at the highest dose accompanied by a significant increase (>100-fold) in glucose excretion in the urine in multiple species including monkeys Secondary improvements in glucose tolerance and insulin sensitivity Significant reduction in ...

Generic Substitutes Less Effective/Safe Than Branded Medications in Treating Lower Urinary Tract Symptoms

... of the medications using several parameters, including the International Prostate Symptom Score (IPSS), peak flow rate (Qmax), post-void residual urine (PVR), voiding diary information, International Index of Erectile Function (IIEF), ejaculatory function and the prevalence of adverse events. ...

Corgenix AspirinWorks(R) Test Recognized in POLYCAP Study at ACC.09

... platelet tests, which require freshly drawn blood that must be evaluated within at least four hours, the AspirinWorks Test is performed on a random urine sample that can be obtained in any doctor's office or patient service center, making the test convenient for both physician and patient. ...

Hyperion Therapeutics Announces Results for Phase II Study in Urea Cycle Disorders

... under the curve (TNAUC) for ammonia. Patients were enrolled on their stable dose of BUPHENYL and 24-hour PK, ammonia measurements, amino acids, and urine collections were completed in a study unit after seven days of on-study treatment. Each patient was then switched to HPN-100 at a dose providing the ...

Galderma Announces Interim Data Relating to Sequential Treatment Regimen of Clobex(R) Spray Followed by Vectical(TM) Ointment in Managing Plaque Psoriasis

... plaque psoriasis in patients 18 years and older. The most frequent adverse events reported in clinical trials (>3%) were lab test abnormality, urine abnormality, psoriasis, hypercalciuria and pruritus. Skin discomfort has also been reported. Vectical(TM) Ointment should be used with caution in ...

PLC Systems Receives Full FDA Approval for Pivotal Study of RenalGuard(TM) in The U.S.

... About RenalGuard RenalGuard is based on existing pre-clinical study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate toxins in contrast media, reducing their harmful effects. RenalGuard is a ...

Swedish in Seattle to Study Connections Between Preeclampsia and Migraine

... with the risk of preeclampsia. Preeclampsia is a vascular disorder characterized by high blood pressure and the presence of protein in the urine starting around mid-pregnancy. It occurs in up to 8 percent of all pregnancies and, in addition to other hypertensive disorders, is the leading ...

Palatin Technologies Presents PL-3994 Clinical Trial Results at the 12th Annual Scientific Meeting of the Heart Failure Association of America

... reduction in systemic blood pressure. PL-3994 produced dose-related decreases in blood pressure, increases in plasma cGMP, and increases in urine volume and sodium excretion. There were no serious or severe adverse events. The data set presented in poster format is available for viewing ...

Clinical Trial Shows Cardiovascular Benefits of Rooibos, Popular Antioxidant Herbal Tea from South Africa

... onions, broccoli, etc.) from their diet for two weeks before initiation of the intervention study. (Analysis of participants' fasted blood and urine samples taken after this period served as a baseline standard to help determine the extent of participant compliance with the study guidelines.) As ...

New Study Offers More Than a Decade of Evidence for Minimally-Invasive Surgery to Treat Female Incontinence

... in the treatment of female SUI." SUI, a condition that affects more than 13 million women in the United States, is the involuntary leakage of urine during routine activities that put pressure on the bladder or urethra, such as laughing, sneezing or coughing. It can be an embarrassing problem that ...

Gene That Causes Childhood Cancer Neuroblastoma Is Found

... possible to offer simple, non-invasive screening for patients with a family history of neuroblastoma," said Mosse. She explained that ultrasound or a urine test could assist surveillance of children with an ALK mutation, so that if neuroblastoma appears, it can be detected at an early stage. "As we ...

Nile Therapeutics Announces Dosing in Second Phase Ib Study of CD-NP in Heart Failure Patients

... infusions of CD-NP in patients with heart failure. Key assessments include glomerular filtration rate, tubular function, renal plasma flow, urine output, mean arterial pressure, and various biomarkers. The trial is expected to enroll 27 heart failure patients. "We are delighted that dosing ...

Findings on Bladder-Brain Link May Point to Better Treatments for Problems in Sleep, Attention

... conditions in both adults and children, is especially prevalent among elderly men, in whom an enlarged prostate gland partially obstructs the flow of urine and makes bladder muscles contract involuntarily. Valentino's research team mimicked the condition in an animal model by surgically constricting the ...

Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference

... known as hypoglycemia. These data are consistent with expectations based on human subjects who have mutations in the SGLT2 gene and have increased urine glucose levels but are otherwise asymptomatic. ISIS 388626 effectively and specifically inhibits the production of SGLT2 in the kidney tissue, ...