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Ulcers in Medical Technology

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... secondary to venous hypertension, venous leg ulcers are increasingly common, are costly, and are ... Characterized as difficult to heal, many such ulcers develop into chronic, nonresponsive wounds ... "Based on an estimated 2.5 million venous leg ulcers in the United States alone and actual direct ...

Horizon Therapeutics' HZT-501 Significantly Reduces Incidence of NSAID-Induced Upper Gastrointestinal Ulcers in Patients With Mild-to-Moderate Pain

... Treatment Decreases Risk of Developing GI ulcers by Approximately 50 Percent-- --Data ... less NSAID-induced upper gastrointestinal (GI) ulcers (gastric and/or duodenal ulcers) compared to ... but they also increase the risk of developing ulcers in the stomach or intestine and the risk of ...

Cardium Announces Completion of Patient Recruitment in Phase 2b Clinical Trial of Excellarate(TM) for the Potential Treatment of Diabetic Foot Ulcers

... for the potential treatment of non-healing foot ulcers in patients with type I or type II diabetes. ... 120 patients with lower extremity neuropathic ulcers that were chronically non-healing despite ... patients enrolled in the study, the mean size of ulcers at treatment was approximately 2.9 cm2 (range ...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... dose aspirin-associated gastric and/or duodenal ulcers in patients at risk. AstraZeneca also ... the risk reduction in the occurrence of gastric ulcers associated with continuous non-steroidal ... aspirin is associated with a risk of peptic ulcers and gastrointestinal symptoms.(3B,3C) These ...

ULURU Inc. to Present Altrazeal(TM) Clinical Evidence and Advanced Therapeutic Research at the Diabetic Foot Global Conference (DFCon) 2009

... use of Altrazeal(TM) in treating diabetic foot ulcers is detailed in a poster titled "Properties of a ... Powder Dressing in the treatment of four separate ulcers in diabetic patients. The treatments were ... at All Country Podiatry in NY. Four cases of ulcers present on heel, toe or ankle are shown and each ...

Healthpoint Initiates Phase II, Dose-Finding Study to Evaluate Effectiveness of a Unique Cell Based Therapy in Venous Leg Ulcers

... placebo plus standard care, in healing venous leg ulcers over a 12-week treatment period. ... 18 years of age and older with venous leg ulcers of at least 6 week's, but not more than 24 months duration. The ulcers must be between 2 cm2 and 12 cm2 in area at ...

New Study Using Combination of Bioengineered Skin and Stem Cells Shows Promise in Treatment of Non-Healing Wounds

... complication of scleroderma is the development of ulcers on the patients' fingers and toes that are very ... skin were used to successfully treat skin ulcers of three scleroderma patients and discussed how ... one patient who had painful and incurable finger ulcers for many years remained healed and free of pain ...

MEDIHONEY(TM) Dressings Shown to Help Improve Outcomes of Non-Healing Venous Leg Ulcers in Recent Case Series

... - particularly in non-healing venous leg ulcers - continues to grow. This case series validates ... in these very difficult to heal leg ulcers. Leg ulcers are very burdensome for patients and their ... in Dallas, April 26-29. About venous leg ulcers Venous ...

OmegaGenesis Unveils Novel Nanotechnology Platform With Broad Biomedical Applications

... is Developing Therapies for Wounds, Diabetic Foot ulcers and Hair Growth Using Nano-Materials with ... therapies for wound healing, diabetic foot ulcers and hair growth are being developed by the ... in the treatment of wound healing, diabetic foot ulcers and hair growth are underway. Clinical trials are ...

Horizon Therapeutics Announces Two Pivotal HZT-501 Phase 3 Trials Meet Primary Endpoints

... upper gastrointestinal (gastric and/or duodenal) ulcers in patients with mild-to-moderate pain when ... taking NSAIDs experience gastrointestinal ulcers and a greater percent suffer from upper GI ... who develop endoscopically diagnosed gastric ulcers during the 24-week treatment period, as compared ...

Derma Sciences' MEDIHONEY(TM) Proven to Speed Healing in Stalled Leg Ulcers

... leg ulcers. Physicians treat over 4 million leg ulcers in the US per year, at a cost exceeding ... controlled clinical trial, looked at venous leg ulcers that had been proven to be non-healing ... reported that MEDIHONEY is effective on stalled ulcers of various etiologies. The recently published ...

New Data Show High Frequency of Medical Claims for Gastrointestinal Events by Patients on Antiplatelet Therapy

... Review of Insurance Claims Tracked ulcers and Bleeding Among 368,000 ... progression of coronary heart disease, ulcers and bleeding can result in patients not taking ... incidence of upper gastrointestinal bleeding and ulcers in patients who take CGT-2168 and aspirin ...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) GENTAMICIN TOPICAL for the Prevention of Diabetic Foot Infections

... for the treatment of mildly infected diabetic ulcers and as an adjunct to systemic antibiotic therapy ... with bacterial pathogens that can prevent ulcers from healing. Many such wounds become clinically ... prevention of infected diabetic foot ulcers and CollaRx Bupivacaine Implant for the ...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) GENTAMICIN TOPICAL for the Treatment of Moderately Infected Diabetic Foot Ulcers

... with bacterial pathogens that can prevent ulcers from healing. A high proportion of such wounds ... of bacterial resistance. Furthermore, diabetic ulcers are often associated with vascular disease and ... for the treatment of infected diabetic foot ulcers and recent market research independently ...

MacroChem Announces Presentation of Pexiganan Phase 3 Study Results for Topical Treatment of Diabetic Foot Infection

... number of diabetic foot infections. Diabetic foot ulcers are a major concern and burden to the ... interventional strategies for diabetic foot ulcers and amputation prevention. Featuring a ... of which about 60% get infected. Diabetic foot ulcers generally result from the consequences of ...

Northern California Foot and Ankle Center Santa Rosa Enrolling Patients With Chronic Diabetic Foot Ulcers for Matrix Clinical Research Trial

... patients with lower extremity diabetic foot ulcers to participate in the MATRIX clinical research ... of foot ulceration. Over 850,000 chronic diabetic ulcers are diagnosed in the U.S. each year. Patients with non-healing ulcers are more susceptible to infections that may lead ...

Associated Foot & Ankle Specialists Enrolling Patients With Chronic Diabetic Foot Ulcers for MATRIX Clinical Trial

... announced it is recruiting patients with foot ulcers due to diabetes to participate in the MATRIX ... of foot ulceration. Over 850,000 chronic diabetic ulcers are diagnosed in the U.S. each year. Patients with non-healing ulcers are more susceptible to infections that may lead ...

Aung FootHealth Clinics & Advanced Wound Care Center Enrolling Patients With Chronic Diabetic Foot Ulcers for Matrix Clinical Trial

... patients with lower extremity diabetic foot ulcers to participate in the MATRIX clinical trial. The ... of foot ulceration. Over 850,000 chronic diabetic ulcers are diagnosed in the U.S. each year. Patients with non-healing ulcers are more susceptible to infections that may lead ...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) GENTAMICIN TOPICAL for the Treatment of Mildly Infected Diabetic Foot Ulcers

... with bacterial pathogens that can prevent ulcers from healing. A high proportion of such wounds ... of bacterial resistance. Furthermore, diabetic ulcers are often associated with vascular disease and ... for the treatment of infected diabetic foot ulcers and recent market research independently ...

MacroChem Acquires Rights to Pexiganan, a Novel Topical Anti-Infective for Treatment of Diabetic Foot Infections, From Genaera

... to treat infected diabetic foot ulcers and that MacroChem is dedicated to the ... foot infections in the U.S. Diabetic foot ulcers in the approximately 20 million diabetics in the ... of which about 60% get infected. Diabetic foot ulcers generally result from the consequences ...

Innocoll Provides a Progress Update on its Clinical Development Programs and Specialty Pharmaceutical Operations

... for the treatment of infected diabetic foot ulcers and recent market research independently ... of painful chronic and acute wounds, including ulcers of various etiologies and burns. Patients with ... and prevention of infected diabetic foot ulcers and Bupivacaine Implant for the management ...

Wound Management Technologies, Inc. Announces Agreement for Evidence Based Study for Diabetic Venous Ulcers

... states Cathy Bradshaw, President of Wound Care Innovations. Venous stasis ulcers of the lower extremity is a common problem among diabetic patients and ... costs to the healthcare system. It has been estimated that venous ulcers cause the loss of approximately 2 million working days and incur treatment ...

Pivotal Pulmonary Arterial Hypertension Study Published in The Lancet Concludes That Bosentan (Tracleer(R)) Demonstrates Benefits in Patients With Mildly Symptomatic WHO Functional Class II Disease

... the EU Tracleer(R) is also indicated to reduce the number of new digital ulcers in patients with systemic sclerosis and ongoing digital ulcer disease. ... have been treated with Tracleer(R). About Tracleer(R) in Digital ulcers (DU) DUs are a manifestation of the underlying vasculopathy which is ...

Randomized Controlled Clinical Trial Shows Derma Sciences MEDIHONEY(TM) Eradicates MRSA From Chronic Venous Ulcers

... 108-patient randomized and controlled clinical trial, looked at venous leg ulcers that had been proven to be non-healing under standard treatment ... Care, the research paper "Bacteriological Changes in Sloughy Venous Leg ulcers Treated with Manuka Honey or Hydrogel: an RCT," was written by lead ...

AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication

... usage section. (4) Lassen et al. Complicated and uncomplicated peptic ulcers in a Danish county 1993-2002: a population-based cohort study. Am J ... therapy in the acute management of patients with bleeding peptic ulcers in the USA and Canada: a cost-effectiveness analysis Aliment ...

Immunosyn Releases Wound Healing Photographs From the First Phase 'Proof of Concept Trial' in Europe for Treatment of Diabetic Ulcers With Biopharmeceutical SF-1019

... which has been successfully completed in Europe for treatment of Diabetic ulcers with SF-1019. (Photo: ... from Diabetic Mellitus such as Diabetic Neuropathy (DN) and diabetic ulcers (DU), auto-immune disorders such as Multiple Sclerosis (MS) and ...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain

... Gentamicin-Collagen sponge for the treatment of infected diabetic foot ulcers and our Gentamicin Surgical Implant for the prevention of surgical site ... Topical for the treatment and prevention of infected diabetic foot ulcers and CollaRx Bupivacaine Implant for the management of post-operative pain, ...

Horizon Therapeutics Initiates Long-Term Phase 3 Safety Study for Lead Product Candidate HZT-501

... demonstrated to significantly reduce the incidence of gastric and duodenal ulcers vs. placebo when administered together with NSAIDs. "This study is ... in the risk of development of ibuprofen-associated upper gastrointestinal ulcers in patients who require the use of ibuprofen. The trials began in March ...

New Powder Speeds Healing of Difficult Foot Wounds

... ) This wound powder is especially promising for the nearly 24 million Americans diagnosed with diabetes. Diabetic foot ulcers are the leading cause of non-traumatic, lower-limb amputations in the United States. In a recent APMA survey, 18 percent of people with diabetes ...

Current Status of the Development Programs of New Indications and Formulations for Aricept(R) for Enhancing Patient Value

... Aricept improves cognition and delays functional decline. Aricept is well tolerated, but may not be for everyone. People at risk for stomach ulcers or who take certain other medicines should tell their doctors because serious stomach problems, such as bleeding, may get worse. Some people who ...

Hand Washing with 4% CHG Antiseptic Kills Flu Viruses

... A leader in trauma and pain management, the Wound Care Division's market dynamics are driven by an aging population, higher incidence of pressure ulcers and increased home treatment. ...

Logical Therapeutics Appoints Peter A. Lankau as CEO and Director

... endoscopies at baseline and on day seven. Subjects receiving LT-NS001 experienced statistically significantly fewer endoscopically confirmed gastric ulcers compared to subjects receiving naproxen. The full results from this study will be presented at scientific meeting during the third quarter of 2009. ...

Rib-X Pharmaceuticals Novel Antibiotic Delafloxacin Named One of R&D Directions 100 Great Investigational Drugs of 2009

... infections involving the deeper soft tissue, including severe cellulitis and major abscesses. These infections may occur in patients with skin ulcers or burns, as well as patients who have undergone surgery or experienced other kinds of trauma. These infections affect over one million patients in ...

Innocoll Announces Dosing of Last Patient in Second US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Colorectal Surgery Patients

... products in Innocoll's development pipeline include CollaRx Gentamicin Topical for the treatment and prevention of infected diabetic foot ulcers and CollaRx Bupivacaine Implant for the management of post-operative pain, both of which are currently in Phase 2 development. For more information, ...

Innocoll Announces Dosing of Last Patient in US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Cardiac Surgery Patients

... products in Innocoll's development pipeline include CollaRx Gentamicin Topical for the treatment and prevention of infected diabetic foot ulcers and CollaRx Bupivacaine Implant for the management of post-operative pain, both of which are currently in Phase 2 development. For more information, ...

ISTA Pharmaceuticals Announces Positive Results for Phase IIb Study of Ecabet Sodium

... dry eye syndrome from Senju Pharmaceuticals Co., Ltd., in November of 2004. Ecabet sodium is already marketed in Japan as an oral agent for gastric ulcers and gastritis by Mitsubishi Tanabe Pharma Corporation (formerly Tanabe Seiyaku Co., Ltd.) as an originator of ecabet sodium. Ecabet sodium ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... of recurrence each year. The risk of blindness increases with the number and severity of recurrences, so prompt treatment of herpetic epithelial ulcers is imperative to limit scarring and other more serious complications. About Durezol Durezol (difluprednate ophthalmic emulsion) 0.05% is a ...

Consensus Document Outlines Practical Steps for Reducing Gastrointestinal Risks of Antiplatelet and NSAID Use

... of Gastroenterology and the American Heart Association today released consensus guidelines outlining a stepwise approach for reducing the risk of ulcers and gastrointestinal (GI) bleeding among patients using nonsteroidal anti-inflammatory drugs (NSAIDs) along with antiplatelet agents. ...

Healthpoint Initiates Randomized, Double-Blind Study to Evaluate Effectiveness of Collagenase SANTYL(R) Ointment on Wound Healing

... enzymatic debriding agent that contains 250 collagenase units per gram of white petrolatum USP. It is indicated for debriding chronic dermal ulcers (e.g., pressure ulcers, vascular ulcers, and diabetic ulcers) and severely burned areas. The enzyme collagenase is derived from the fermentation by ...

Cardium Reports on Second Quarter 2008 Highlights and Financial Results

... the study. The MATRIX clinical trial is evaluating the safety and efficacy of Excellarate for the potential treatment of non-healing diabetic foot ulcers and is expected to enroll up to approximately 210 patients at up to 40 U.S. sites. The study has also been the focus of media attention in multiple ...
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