transport

Lab Automation Networks Proliferating

...n, recapper, sorter, storage and retrieval device, transport system and workstation, all coordinated by proprietary process control software. Like Beckman Coulter, the systems design is based on an open system philosophy, so interface with a wide variety of analyzers from all major manufactures is easily imple...

Blood Gas Analysis: The Pros and Cons of Point-Of-Care Testing

... and transported for immediate analysis. To reduce transport as well as turnaround time, especially for the mos...ch as rural clinics and in ambulance or helicopter transport situations. POCT can offer several benefits, most importantly the instant implementation of treatmen...

Cytokinetics Reports Additional Clinical Trials Data for Ispinesib

...ilaments that areresponsible for the long-distance transport of important cellularcomponents within nerve cells. Mitotic kinesins are essential to mitosis, and, unlike tubulin,appear to have no role in other cellular functions. Cytokinetics believes that drugs that inhibit KSP and CENP-E andother mitotic kine...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

...in. The clinical relevance of hOAT-3in sitagliptin transport has not been established. Sitagliptin is alsoa sub...trate, but does not inhibit p-glycoproteinmediated transport of digoxin. Based on these results, sitagliptin isconsidered unlikely to cause interactions with oth...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

...in. The clinical relevance of hOAT-3in sitagliptin transport has not been established. Sitagliptin is alsoa sub...trate, but does not inhibit p-glycoproteinmediated transport of digoxin. Based on these results, sitagliptin isconsidered unlikely to cause interactions with oth...

Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer

...rocesses. PDX was rationally designed forefficient transport into tumor cells via the reduced folatecarrier, or RFC-1, and effective intracellular drug retention. TheCompany believes these biochemical features, together withpreclinical and clinical data in a variety of tumors, suggest thatPDX may have a favora...

BioLineRx Presents Data From Successful Phase I Trial for BL-1020 in Schizophrenia at American Psychiatric Association Conference

...studiesdemonstrate that BL-1020 provides effective transport of GABA intothe brain, overcoming this challenge. Receptor binding studiesindicate that BL-1020 has a high affinity to dopamine and specificGABA-A agonist activity. This unique clinical profile may explainthe reduction in side effects observed in ani...

Allos Therapeutics' PDX Granted Orphan Medicinal Product Designation by the European Commission

...rocesses. PDX was rationally designed forefficient transport into tumor cells via the reduced folatecarrier, or RFC-1, and effective intracellular drug retention. Webelieve these biochemical features, together with preclinical andclinical data in a variety of tumors, suggest that PDX may have afavorable potenc...

AGI Dermatics Presents Comparative Data That Indicates OCTN-1 Skin Cells Have the Ability to Recognize, Transport and Utilize L-ergothioneine (EGT) As A Protector Against Oxidative Damage

...t OCTN-1 skin cells have the ability to recognize, transport andutilize L-ergothioneine (EGT) as a protector against oxidativedamage, and importantly, that (EGT) acts as a more powerful andefficient antioxidant than idebenone, scavenging reactive oxygenspecies and reducing UV-induced hydrogen peroxide (H2O2). ...

New Research Results Show That Investigational Drug Phenoxodiol Targets Cancer Protein, Causing Cancer Cell Death

.... Berridge. "Byinhibiting plasma membrane electron transport selectively in cancercells, phenoxodiol subjects t... a cancer specific surfaceplasma membrane electron transport element on cancer cells therebyinhibiting their proliferation, whereas the compound has no sucheffec...

Apollo develops needle-free topical vaccine

...e[5] * Topical vaccines are cheaper and easier to transport and storenon-injected medicines, increasing access to vaccines[6] * Needle stick injuries are a significant problem in bothdeveloped and developing countries. It is estimated that 5 in every100 injections worldwide result in a needle-stick accident....

XenoPort Reports Positive Top-Line Phase 3 Trial Results of XP13512 in Restless Legs Syndrome

... of gabapentin by taking advantageof high-capacity transport mechanisms in the gastrointestinal tractto improve...candidatesthat utilize the body's natural nutrient transport mechanisms toimprove the therapeutic benefits of existing drugs. XenoPort's mostadvanced product can...

Mircera Effective in Stabilising Haemoglobin Levels in Elderly Patients With Kidney Disease on Dialysis

... stimulatethe production of red blood cells, which transport theoxygen-carrying protein, haemoglobin, throughout the body. Renalanaemia is present in the early stages of CKD and becomesincreasingly common and more severe and more common as the diseaseprogresses. In fact, as patients reach end-stage renal disea...

EntreMed Presents Preclinical Data for MKC-1 in Hematological Cancers

...amily of proteins plays a critical role in nuclear transport andcell division. In these studies, MKC-1 showed potent, dose-dependent activityagainst a variety of cell lines derived from cancers of human bloodcells, and inhibited growth of primary cells derived from acute andchronic myelogenous leukemia (AML...

Abraxis BioScience Presents Results from Pre-Clinical Study That Demonstrates nab-Rapamycin's Robust Antitumor Properties and Ability to Target Intracellular Sites Such as the mTOR Pathway

...naturalproperties of the human protein albumin, to transport and delivertherapeutic agents to the site of disease. The binding of albuminto the anticancer agent creates nanometer-sized particles, whichare approximately 1/100th the size of a single red blood cell.These nab particles are readily incorporated int...

Abraxis BioScience Presents Pre-Clinical Findings That Support Role of SPARC Expression in Cancer and the Role of the Nanoparticle Albumin Bound (nab) Technology Platform in Targeting the Pathway

...roperties of albumin,nab-technology allows for the transport and delivery of higherconcentrations of anticancer...naturalproperties of the human protein albumin, to transport and delivertherapeutic agents to the site of disease. The binding of albuminto the anticancer agent ...

Abraxis BioScience Presents Data from Pre-Clinical Study That Provide Evidence for Chemotherapy-Induced Angiogenesis and Rationale for Combining nab-Paclitaxel (Abraxane) with Anti-Angiogenic Agents to Increase Tumor Response

...naturalproperties of the human protein albumin, to transport and delivertherapeutic agents to the site of disease. The binding of albuminto the anticancer agent creates nanometer-sized particles, whichare approximately 1/100th the size of a single red blood cell.These nab particles are readily incorporated int...

Arrowhead Subsidiaries Insert & Calando Present Data on Cyclosert Drug Delivery System at AACR Meeting

...system." Cyclosert is the first nanoparticle drug transport platform tobe designed de novo and synthesized specifically to overcomelimitations in existing technologies used for the systemictransport of therapeutics to targeted sites within the body. Basedon small cyclic repeating molecules of glucose calledcy...

Poster on Cyclosert Drug Delivery Presented at AACR Meeting

...lopment. Cyclosert is the first nanoparticle drug transport platform tobe designed de novo and synthesized spe...so highly toxic. By combining it withthe Cyclosert transport system, researchers are aiming to make itnon-toxic while preserving its antitumor activity. In vitr...

Cytokinetics Announces Non-clinical Data to be Presented at the 2007 AACR Annual Meeting

...laments that are responsible for the long-distance transport ofimportant cellular components within nerve cells. Mitotic kinesins are essential to mitosis, and, unlike tubulin,appear to have no role in unrelated cellular functions.Cytokinetics believes that drugs that inhibit KSP and CENP-E andother mitotic k...

Preclinical Data on Cytogen's Technology to be Reported at the AACR Annual Meeting

...se oral delivery agents are capable offacilitating transport of an active agent from the lumenal side ofthe GIT...drugs can betargeted to specific receptor sites or transport pathways known tooperate in the human gastrointestinal tract, thus facilitating itssystemic absorpti...

Amicus Therapeutics Presents Preclinical Data from Studies of Plicera for Gaucher Disease

...CMG. - In vitro exposure to Plicera increased transport of GCase to the lysosomes in cells derived from a patient with the N370S mutation. Once in the lysosome, the enzyme was stable and active for more than 3 days after Plicera was removed. The N370S is the most common mutation associ...

Liponex Inc. Reports Phase I/II Clinical Trial Data for CRD5

... candidates relate to the various rolesof HDL as a transport vehicle, including removing excesscholesterol from the body, delivering molecules to cells andremoving unwanted materials from the body. Liponex is listed on theTSX under the ticker "LPX". For more information on Liponex, visit <a target="_blank"...

AOP Orphan Pharmaceuticals and Lantibio Announce Positive Phase II Study with Novel Cystic Fibrosis Therapy

... channel CFTRcauses reduced chloride ion and water transport in respiratoryepithelial cells. This results in an...udies, Moli1901has been shown to increase chloride transport and fluid secretionswhen applied to airway epithelium in-vitro, and increases chloridepermeability i...