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Toxins in Medical Technology

Human Genome Sciences Submits Biologics License Application to FDA for ABthrax(TM)

... level. After protective antigen and the anthrax toxins are produced by the bacteria, protective antigen ... complex that makes it possible for the anthrax toxins to enter the cells. Raxibacumab blocks the ... antigen to cell surfaces and prevents the anthrax toxins from entering and killing the cells. ABOUT ...

Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile

... attacks. It specifically targets the deadly toxins released within the human body by Bacillus ... they are not effective against the deadly toxins that the bacteria produce. ABthrax targets anthrax toxins after they are released by the bacteria into the ...

New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies

... ABthrax, which specifically targets anthrax toxins and is being developed under contract with the ... they are not effective against the deadly toxins that the bacteria produce -- the real culprits in ... but are not effective against the anthrax toxins once ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... to stop the production of destructive intestinal toxins caused by Clostridium difficile (C. difficile) ... condition caused by potentially lethal toxins that enter and then kill healthy cells in the ... to inhibit growth of the bacteria. The levels of toxins were monitored by immunoassays using antibodies ...

ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers

... two-way transfer of metabolites. During ELAD therapy the cells metabolize toxins and synthesize proteins and other liver specific products essential for ... could provide support for patients with severe liver failure by processing toxins and synthesizing proteins and metabolites that are key products of normal ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Sporulation in Clostridium difficile

... Canada. The BI/NAP1/027 outbreak strains produce greater amounts of toxins A and B, have increased sporulation capacity, and cause more severe ... C. difficile strain (BI/NAP1, 027) that produces high levels of toxins poses a real threat to public health and demands improved infection ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... However, antibiotic therapy, while useful, is believed to be associated with a number of limitations, including: (1) lack of activity against the toxins produced by the B. anthracis bacteria, (2) need for long-term dosing to achieve full protection, complicated by side effects and non-compliance (3) ...

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

... and in the community. It is a serious illness caused by infection of the inner lining of the colon by C. difficile bacteria, which produce toxins that cause inflammation of the colon, severe diarrhea and, in the most serious cases, death. CDI typically develops from the use of broad-spectrum ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... However, antibiotic therapy, while useful, is believed to be associated with a number of limitations, including: (1) lack of activity against the toxins produced by the B. anthracis bacteria, (2) need for long-term dosing to achieve full protection, complicated by side effects and non-compliance (3) ...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... bacterium, which under certain circumstances, typically after antibiotic therapy, can colonize the lower gastrointestinal tract where it may produce toxins which cause inflammation of the colon and diarrhea. Without proper treatment, the associated complications of the disease can be deadly. Advanced ...

Got Pain?

... of Medicine and president of the American Society for Surgery of the Hand (ASSH) is successfully using another type of injection therapy, Botulinum toxins on patients with nerve pain. The results of this type of less invasive procedure are very favorable. Additionally, Koman said, "nerve pain may be ...

British Midlands University Announces Use of Gene Technology to Fight Lethal Hospital Acquired Infection

... the disease. Currently, scientists know that the bacteria cause disease by sticking to epithelial cells of the gut lining and releasing two toxins that damage cells leading to the tell-tale symptom of severe diarrhea. However, there is very little known about the ways in which the bacteria ...

PLC Systems Receives Full FDA Approval for Pivotal Study of RenalGuard(TM) in The U.S.

... study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate toxins in contrast media, reducing their harmful effects. RenalGuard is a fully-automated, real-time matched fluid replacement device intended for ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... the onset of the illness by attaching to cells in the infected person, and then is believed to facilitate the entry of additional destructive toxins into the cells. Valortim(R) is designed to target anthrax protective antigen and protect the cells from damage by the anthrax toxins. About ...

Iomai Announces Publication in The Lancet of Phase II Study Demonstrating Significant Efficacy of Travelers' Diarrhea Vaccine

... uses an ETEC toxin delivered via a skin patch using the company's novel transcutaneous immunization (TCI) technology. ETEC causes illness through the toxins it produces, including one known as heat-labile toxin or LT. Iomai's unique patch-based vaccine enables the safe administration of this potent ...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

... on existing study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate toxins in contrast media, reducing their harmful effect. RenalGuard is a fully-automated, real-time matched fluid replacement device intended for ...

Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives

... for B-cell modulation in the treatment of relapsing-remitting MS. ABthrax(TM) (raxibacumab), a human monoclonal antibody that prevents anthrax toxins from entering and killing cells, for the treatment of anthrax disease HGS reported in December 2007 that the results of two animal ...

Arbios Receives Approval From the FDA to Initiate Pivotal Trial for SEPET(TM) Liver Assist Device

... of specific molecular weights are expressed through the micropores, thereby cleansing the blood of harmful impurities (e.g., hepatic failure toxins as well as various mediators of inflammation and inhibitors of liver regeneration). These substances would otherwise progressively accumulate in the ...

Dr. Peter Nash, Ph.D. Joins Mach One Corporation as Chief Scientist

... swab tests to detect Listeria in feedlots and E. coli in processing plants. Dr. Nash also developed tests for strep, whooping cough, salmonella, toxins and other diagnostics. During the first Gulf War, he worked on anthrax tests until government funding dissipated. Along with two others, Dr. Nash ...

PLC Systems Receives FDA Approval to Commence Pivotal Study Of RenalGuard(TM) In the U.S.

... study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate toxins in contrast media, reducing their harmful effects. RenalGuard is a fully-automated, real-time matched fluid replacement device intended for ...

Arbios Receives Conditional Approval from the FDA to Initiate Pivotal Clinical Trial for SEPET(TM)

... of specific molecular weights are expressed through the micropores, thereby cleansing the blood of harmful impurities (e.g., hepatic failure toxins as well as various mediators of inflammation and inhibitors of liver regeneration). These substances would otherwise progressively accumulate in the ...

Michael J. Fox Foundation Awards Up to $3 Million to Industry Teams to Jumpstart Promising PD Drug Development

... 'energy factories' of body cells. It is believed that mitochondrial function is decreased in people with Parkinson's disease and that mitochondrial toxins induce parkinsonian symptoms in animal models. Rebecca Pruss, PhD, and her colleagues at Trophos are developing unique compounds that improve ...

PLC Medical Systems Names Lead Investigators for Pivotal Trial to Evaluate RenalGuard System(TM) and RenalGuard Therapy(TM)

... study data that suggests that initiating and maintaining high urine output during imaging procedures allows the body to rapidly eliminate toxins in contrast media, reducing their harmful effects. The RenalGuard System(TM) is a fully-automated, real-time matched fluid replacement device ...

Vital Therapies Announces Presentation of ELAD(R) 'Artificial Liver' Data at American Association for the Study of Liver Diseases 2007 Annual Meeting

... of liver disease. The system consists of four cartridges containing cells that function like normal human liver hepatocytes. The cells metabolize toxins and remove waste products while delivering essential proteins into the plasma. These cartridges are incorporated into a blood pumping system at the ...

Ocera Therapeutics, Inc. Completes Enrollment in FHAST1, a Pivotal Phase 3 Clinical Trial in Fistulizing Crohn's Disease

... of Phase 2 trials with AST-120 in Irritable Bowel Syndrome and Hepatic Encephalopathy. AST-120 is an oral agent known to adsorb bile acids, toxins and mediators of inflammation from the gastrointestinal tract with the potential to address multiple gastrointestinal diseases. Ocera in-licensed ...

Arbios Provides Clinical Strategy for SEPET(TM) Pivotal Trial

... of specific molecular weights are expressed through the micropores, thereby cleansing the blood of harmful impurities (e.g., hepatic failure toxins as well as various mediators of inflammation and inhibitors of liver regeneration). These substances would otherwise progressively accumulate in the ...

Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea

... antibiotic therapy. Tolevamer is designed to bind and neutralize the toxins released by C. difficile that damage the intestine. A ... antibiotics. Once established in the colon, C. difficile produces toxins that disrupt the intestinal lining, causing cell death and inflammation ...

New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy

... also is developing its calcium phosphate nanotechnology (CaP) for novel vaccines, including hepatitis B, avian flu and biodefense vaccines for toxins such as anthrax, as well as a system for delivering drugs via alternative routes of administration. Additional information is available online at ....

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

... of a large population. The only vaccine available is an experimental vaccine based on inactivation of a mixture of serotypes of the natural toxins that is given by injection, is not licensed by the FDA and cannot be used for widespread immunization. New multivalent vaccines based on non-toxic ...

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC

... of a large population. The only vaccine available is an experimental vaccine based on inactivation of a mixture of serotypes of the natural toxins that is given by injection, is not licensed by the FDA and cannot be used for widespread immunization. New multivalent vaccines based on non-toxic ...

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

... also is developing its calcium phosphate nanotechnology (CaP) for novel vaccines, including hepatitis B, avian flu and biodefense vaccines for toxins such as anthrax, as well as a system for delivering drugs via alternative routes of administration. Additional information is available online at ....
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(Date:11/24/2009)...Scientists have crystallised a protein that may he.... The protein could be used by probiotic producers... benefit to people. , "Probiotics need to interac...ffect, and if they attach to surfaces in the gut t... exert their activity," says Dr Nathalie Juge from...
(Date:11/24/2009)... BATON ROUGE Antarctica has long held secrets of... until recently, there has been very little inform...neath miles of ice for millions of years. Now, a t...ng LSU have been funded to the tune of $10 millio...SF, to get to the bottom of things literally. The...
(Date:11/23/2009)...Washington, D.C. The community-associated strain ...cteria resistant to most common antibioticsposes a...nd is making its way into hospitals, according to ...ous Diseases . , The new threat is easily picke... places and has increased the overall burden of MR...
Breaking Biology News(10 mins):A sticky solution for identifying effective probiotics 2LSU gets to the bottom of things -- in Antarctica 2New study finds MRSA on the rise in hospital outpatients 2The Maurer Foundation for Breast Health Education Launches Integrated Rebranding Operation 52200 1The Maurer Foundation for Breast Health Education Launches Integrated Rebranding Operation 52200 2Swissmedic Grants Debiopharm Marketing Authorisation for Moapar 28R 29 a New Therapeutic Avenue for the Treatment of Sexual Deviations 4759 1Swissmedic Grants Debiopharm Marketing Authorisation for Moapar 28R 29 a New Therapeutic Avenue for the Treatment of Sexual Deviations 4759 2Swissmedic Grants Debiopharm Marketing Authorisation for Moapar 28R 29 a New Therapeutic Avenue for the Treatment of Sexual Deviations 4759 3JACQUES Initiative Joins Maryland AIDS Administration to Extend HIV Testing to the Faith Based Community 52195 1JACQUES Initiative Joins Maryland AIDS Administration to Extend HIV Testing to the Faith Based Community 52195 2JACQUES Initiative Joins Maryland AIDS Administration to Extend HIV Testing to the Faith Based Community 52195 3JACQUES Initiative Joins Maryland AIDS Administration to Extend HIV Testing to the Faith Based Community 52195 4
(Date:11/27/2009)...Health™ announced today that Spectrum Health...ad Enterprise orthopedic templating solution and i... (PRWEB) November 27, 2009 -- Voyan...th (Grand Rapids, Michigan) has licensed its Traum... its TraumaCad Extend workflow solution, to allow ...
(Date:11/27/2009)...ist manufacturers who use medical load cells at th...ollars by bringing in technology partner Flintec e...pro-active medical manufacturers are calling in Fl...eir projects, ensuring that progress will not be c...ally outdated technology. , ...
(Date:11/26/2009)...Newswire/ -- With cold and flu season upon us, it,...s to control the spread of infections and avoid il...keep ourselves healthy, but to avoid transmitting ...S, CIC (certified in infection-control), nursing d...lth at Hospital for Special Surgery (HSS) in Manha...
(Date:11/26/2009)...r of Americans living with diabetes will nearly do... million in 2034. Over the same period, spending o...llion to $336 billion, even with no increase in th...University of Chicago report in the December issue...diabetes covered by Medicare will rise from 8.2 mi...
(Date:11/26/2009)...vy can lead to strains or worse , , THUR...hing wrong with stuffing your turkey full to burst...ith your suitcase as you pack for holiday trips. ,...n U.S. hospital emergency rooms, doctors, offices,...related injuries, such as muscle strains, pulls an...
Breaking Medicine News(10 mins):Health News:Voyant Health Announces: Spectrum Health Licenses TraumaCad Enterprise and TraumaCad Extend 2Health News:Voyant Health Announces: Spectrum Health Licenses TraumaCad Enterprise and TraumaCad Extend 3Health News:Pro-active Manufacturers Save Millions with Advanced Flintec Medical Load Cells 2Health News:Pro-active Manufacturers Save Millions with Advanced Flintec Medical Load Cells 3Health News:Pro-active Manufacturers Save Millions with Advanced Flintec Medical Load Cells 4Health News:Infection-Control Strategies at Leading Hospital Can be Adapted for Everyday Use 2Health News:Infection-Control Strategies at Leading Hospital Can be Adapted for Everyday Use 3Health News:Infection-Control Strategies at Leading Hospital Can be Adapted for Everyday Use 4Health News:Diabetes cases to double and costs to triple by 2034 2Health News:Diabetes cases to double and costs to triple by 2034 3Health News:Pack Right for the Holidays to Avoid the ER 2
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