A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer
... with increased risk of BCC and also with risk of
cancer of the lung, bladder and prostate. Rs 2736089 is located in the gene
encoding the human
telomerase reverse transcriptase (TERT), which directs the
addition of repeat DNA sequences to the ends of chromosomes. Importantly, the
risk of these different ...
Vical Receives Milestone Payment from Merck & Co., Inc. Triggered by Planned Initiation of Investigational Cancer DNA Vaccine Trial
... of an investigational plasmid DNA (pDNA) cancer vaccine. The candidate vaccine is based on Vical's DNA gene delivery technology and encodes human
telomerase reverse transcriptase (hTERT). hTERT is the subject of separate license agreement.
"The breadth of applications for Vical's gene delivery ...
Telomerase Presentations at the AACR 2007 Annual Meeting
... referenced multiple presentations
on the role of
telomerase and telomeres in cancer at this year's
American ... approximately 80 presentations on telomere
and
telomerase biology reflecting the growing body of evidence
supporting the importance of
telomerase as a universal cancer
target for drug and vaccine ...
Geron's Telomerase Inhibitor Cancer Drug Demonstrates Good
Pharmacokinetics and Tolerability in Phase I/II Trial
... 12, 2007 - Geron
Corporation's (Nasdaq:GERN)
telomerase inhibitor cancer drug,
GRN163L, has demonstrated ... uncertain at this time
given the lack of measured
telomerase inhibition in this
patient.
"We are encouraged ... results," said Dr. Colowick. "The
first and only
telomerase inhibitor in clinical trials continues ...
Geron Corp. Licensee TA Sciences Announces Landmark 7/07/07
Teleconference to Answer Questions About TA-65, Their Telomerase
Activator With Proven Age Management Benefits
... NEW YORK, June 15, 2007 /PRNewswire/ --
telomerase Activation
Sciences, Inc. (T.A. Sciences) ... and positive anti-aging
benefits from a
telomerase Activator. Statistically significant
results were ... of the vast,
powerful, and tangible benefits of a
telomerase Activator in human
aging. This trial has been ...
Research Indicates Geron's Human Embryonic Stem Cell-Based
Therapeutic for Spinal Cord Injury Evades Direct Attack by the
Human Immune System
... cord injury, heart failure, diabetes and HIV/AIDS. The
company is advancing an anti-cancer drug and a cancer vaccine that
target the enzyme
telomerase through multiple clinical trials.
Geron is also the world leader in the development of human
embryonic stem cell-based therapeutics, with its spinal ...
Research Documents Scalable Production, Survival Following
Engraftment and Positive Impact on Cardiac Function in Infarcted
Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for
Heart Failure
... cord injury, heart failure, diabetes and HIV/AIDS. The
company is advancing an anti-cancer drug and a cancer vaccine that
target the enzyme
telomerase through multiple clinical trials.
Geron is also the world leader in the development of human
embryonic stem cell-based therapeutics, with its spinal ...