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BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

... more than250 million chickens have been killed to stop the spread of thevirus. Farmers and poultry producers already have suffered lossesin the billions of dollars. There is widespread concern that astrain of avian flu will mutate into a new form that is contagiousamong humans. Since there is currently n...

Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression

...cs." "Demonstrating how p53 utilizes microRNAs to stop the growth oftumor cells through facilitating apoptosis, sheds much light onthis critical cancer fighting pathway," said Prof. Moshe Oren ofthe Weizmann Institute, Principal Investigator of this study."MicroRNAs have been shown to be involved in the ...

Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients

...arceva outside of a clinical trial may belikely to stop treatment. “Some patients are stopping treatment because of the rash,yet those are the ones who are most likely to benefit,”Wacker said. “This is a critical problem and rather thanpermanently discontinue treatment, patients should...

Neuroblastoma Expert Reviews Progress and Challenges in Fighting Difficult Pediatric Cancer

...gets in biological pathways, so we canintervene to stop neuroblastoma in its tracks," said Maris. Support for the paper was provided in part by the NationalInstitutes of Health, the Children's Oncology Group, and a varietyof private foundations and organizations. In addition to hisposition at Children's ...

Vical Licensee AnGes MG Announces Positive Results of Phase 3 Angiogenesis Trial in Japan

... AMG0001 is confirmed, thecommittee recommended to stop this trial in order to preventpotential ethical is...AnGeshas accepted this advice today and decided to stop this trial. Fromnow on, AnGes will closely communicate with governmental agenciesand prepare for NDA...

Three Studies Suggest Abbott's Humira (adalimumab) May Improve Work Productivity in Patients with Rheumatoid Arthritis

...hs longer and were 36 percent less likely to stop working than the patients in the DMARD registry. "Rheumatoid arthritis can have a profound impact on the lives ofpatients. Within three years of diagnosis some people who developthe condition have to give up full-time employment," said Rebecca...

Three New Drugs Mark New Era in Rheumatoid Arthritis Treatment

...,and to some extent glucocorticoids, can impede or stop theinflammatory and destructive disease processes. Methotrexate is themost widely used DMARD and is a cornerstone of most RA treatmentregimens. Of the three new drugs, rituximab and abatacepthave been approved for RA treatment, while the third, toci...

Repros Reports That Proellex Has Demonstrated Superior Efficacy and Safety in Endometriosis When Compared to Standard of Drug Care

... and curettage(D&C) procedure was performed to stop the bleeding. A similarevent has not been seen at the 50mg dose during the treatmentphase. Greater than normal bleeding occurred in two patients in the50mg Proellex group after treatment was stopped and a D&C wasperformed in one and the other suc...

NCI Researchers Discover Genes That Are Turned on at High Levels in Tumor-associated Blood Vessels of Mice and Humans

...istant sites inthe body. Researchers have tried to stop disease-relatedangiogenesis by identifying the molecules that stimulate bloodvessel and developing new drugs to block their action. However,blocking angiogenesis requires a delicate balance between tumor andnormal cells as most angiogenesis-related m...

ProEthic Pharmaceuticals Presents Positive Data for PRO-513 at American Headache Society Meeting

...pain relief took too long and 25percent decided to stop seeking treatment all together. PRO-513 Development History In 2005, ProEthic obtained exclusive U.S. and Canadian marketingrights for PRO-513 from APR, Applied Pharma Research, a Swiss drugdelivery and drug development company. The product candida...

Trial Results with Intranasal Fentanyl Hold Promise for Treatment of Breakthrough Pain in Cancer

...gary, June, 7, 2007--A pioneering nasal spraycould stop thousands of patients with cancer from sufferingunnecessary pain; it was reported today1 at the 10th Congress ofthe European Association for Palliative Care, Budapest, 7–9June. The study investigated whether this first in class novelformulation...

Waismann Method Survey Reveals Dependency Risk for People Using Suboxone

...wn as Subutex or Buprenorphine, believe theycannot stop taking the drug without assistance, indicating aphysical dependency. Suboxone is often prescribed to treatdependency to opiates including OxyContin, Vicodin, Lortab orFentanyl. Because Suboxone is 50 percent opiate in composition, ithelps alleviate p...

Limiting Eligibility for Medical Studies Can Omit Women, African-Americans, Stanford Study Finds

...yonewho is depressed in my alcohol study,' and not stop to considerthat the majority of depressed people a...so urging designers ofalcohol treatment studies to stop excluding patients with drugproblems. "Eighty percent of patients with alcohol problems usesome sort...

Study Suggests Strattera Improved ADHD Symptoms in Patients With Comorbid Alcohol Abuse

...xperienced side effectswere not bothered enough to stop using Strattera. The most commonside effects in children and adolescents in medical studies wereupset stomach, decreased appetite, nausea and vomiting, dizziness,tiredness and mood swings. In adults, the most common side effectswere constipation, dry...

FDA Proposes New Warnings About Suicidal Thinking, Behavior in Young Adults Who Take Antidepressant Medications

...ly prescribed antidepressant medications shouldnot stop taking them. Those who have concerns should notify theirhealth care providers. The proposed labeling changes apply to the entire category ofantidepressants. Results of individual placebo-controlledscientific studies are reasonably consistent in show...

Pegasys Study Authors Conclude that Patients Successfully Treated for Hepatitis C Can be Considered ''Cured''

...ost patients, these conditions get betterafter you stop taking PEGASYS (see medication guide for moreinformation and warnings). What is COPEGUS? COPEGUS is a medicine that works by slowing down the growth ofthe virus. COPEGUS should be taken with PEGASYS to fight the virus.Do not take COPEGUS by itself....

Baraclude (Entecavir) Treatment Demonstrated Greater Viral Load Reduction Compared to Adefovir at 48 Weeks in Study of Antiviral-Naive Chronic Hepatitis B E-Antigen Positive Patients

... damaging the liver. BARACLUDE does notcure HBV or stop the spread of HBV to others. People should not ta...toms may get worse or becomevery serious when they stop taking BARACLUDE. People should notstop BARACLUDE without talking to their healthcare provider.Healt...

Data Suggest that Pegasys May be an Option in Hepatitis C Patients Unable to Tolerate Peg-Intron

...ost patients, these conditions get betterafter you stop taking PEGASYS (see medication guide for moreinformation and warnings). What is COPEGUS? COPEGUS is a medicine that works by slowing down the growth ofthe virus. COPEGUS should be taken with PEGASYS to fight the virus.Do not take COPEGUS by itself....

Survey: Migraine Patients Taking Potentially Addictive Barbiturate or Opioid Medications Not Approved by FDA as Migraine Treatments

.... Not All Migraine Treatments Are Equal Triptans stop a migraine attack after the attack begins bystimulating serotonin, which reduces inflammation and constrictsblood vessels, thereby alleviating the symptoms of migraines suchas pain, nausea and sensitivity to light and sound. Although barbiturates an...

PTC Therapeutics Announces Additional Positive Interim Phase 2 Results of PTC124 in Duchenne Muscular Dystrophy

...and did not induceribosomal read through of normal stop codons. PTC is currentlyconducting Phase 2 clinical trials of PTC124 innonsense-mutation-mediated cystic fibrosis (CF) and Duchennemuscular dystrophy (DMD). It is estimated that 10% of the cases of CF and 13% of the casesof DMD are due to nonsense m...

Clinical Trial Results Suggest Long-Term Treatment Benefit of Tetrabenazine for Chorea Associated with Huntington's Disease

... burden." Tetrabenazine is designed to reversibly stop the release ofdopamine, a brain chemical involved in abnormal movements such aschorea. Chorea can be a debilitating feature of a number ofneurological diseases, characterized by excessive, involuntary andrepetitive movements that may flow from one bo...

Targeting Specific Mutations Reveals Promising New Approach to Treating Genetic Disorders; Preclinical Data Published in Nature

...se mutations,allowing the readthrough of premature stop codons and therestoration of the production of ful...al models, and did not induce readthroughof normal stop codons. PTC is currently conducting Phase 2 clinicaltrials of PTC124 in nonsense-mutation-mediated c...

Alnylam Announces Advancement of a New RNAi Therapeutic Development Program for the Treatment of Liver Cancer

...ce both VEGFand KSP expression in the liver and to stop cancer cellproliferation by targeting KSP. Specifically, the pre-clinical datashowed: -- Durable and rapid reduction in vivo of VEGF protein by morethan 50 percent after a single injection of a VEGF-specific siRNAin a rodent model; -- Silencing of ...

Interim Results Presented at EASL from PROVE 1 Clinical Trial of Investigational Drug Telaprevir in Patients with Genotype 1 Hepatitis C

... study protocol, patients in Arm D wereeligible to stop all treatment at week 12 if they met on-treatmentcriteria, including the achievement of RVR ((less than)10 IU/mL atweek 4) and maintenance of this viral response ((less than)10IU/mL) at week 10 of treatment. Nine of 17 patients met thesecriteria and ...

Baraclude (entecavir) Therapy Resulted in Undetectable Levels of Hepatitis B Virus in Cohort of Patients Who Re-Started Treatment

... damaging the liver. BARACLUDE does notcure HBV or stop the spread of HBV to others. People should not ta...toms may get worse or becomevery serious when they stop taking BARACLUDE. People should notstop BARACLUDE without talking to their healthcare provider.Healt...

Scientists Implicate Gene in Vitiligo and Other Autoimmune Diseases

...cess. In fact, it may even be possible to actually stop theautoimmune disease, he says. The most immediate application of this research might be for thedisease that began the research: vitiligo. Doctors usually treatvitiligo with ultraviolet (UV) light to stimulate skinrepigmentation. Scientists also kno...

Rapid Response was Crucial to Containing the 1918 Flu Pandemic

...oked at 16U.S. cities for which both the start and stop dates ofinterventions were available. Schools, theaters, churches and dance halls in cities across thecountry were closed. Kansas City banned weddings and funerals ifmore than 20 people were to be in attendance. New York mandatedstaggered shifts at ...

Targanta Reports Improved Ability of Oritavancin to Stop Bacteria Growth In Vitro Compared With Other Glycopeptide Antibiotics

...dies showing theimproved potency of oritavancin to stop bacterial growth in vitrowhen tested with a common...hich maintains ORI available in solution to stop growth of bacteria. Investigators also concluded that current literature on ORI MICs, without...

Once Daily, Extended-Release Ropinirole Improves Parkinson's Symptoms in Patients not Optimally Controlled With Levodopa

...vements). Most patientswere not bothered enough to stop taking REQUIP. This is not acomplete list of side effects and should not take the place ofdiscussions with patients' healthcare providers. Their doctor orpharmacist can give patients a more complete list of side effects.Patients should talk to their ...

First Study To Show Positive Benefit On Atherosclerosis For People With Early Signs Of Diseased Arteries

... using rosuvastatin wecan potentially slow or even stop the disease progression in peoplewith relatively modest atherosclerosis,” said leadinvestigator John R. Crouse, III, M.D., Professor of Medicine andPublic Health Sciences and Associate Director of the Wake ForestUniversity School of Medicine (W...

Two New Imaging Studies Show Higher Dose Lipitor Stopped the Progression of Atherosclerosis

...rkable in thesestudies is that Lipitor was able to stop the progression ofdisease, including the most difficult to treat FH patients studiedin RADIANCE 1," said Professor John Kastelein, lead investigatorfor two of the trials, and professor of medicine and chairman ofvascular medicine at the Academic Medi...

REACH Registry Demonstrates That Multiple Arterial Disease Locations Sharply Increase the Risk of Major CV Events in Outpatients With Atherothrombosis

...f event in REACH shows that it is critical that we stop viewingatherothrombosis as a disease of a specific medical specialty -cardiology, neurology, or vascular disease - instead we must viewit as a 'global' disease, Doctors' adherence to evidence-basedguidelines for treatment are important to manage the ...

Scottish Scientists Test ‘Secret Weapon’ Against Tumours

...ental treatment that cancause malignant tumours to stop growing. In laboratory tests itkilled a range of different cancer cells. We look forward to seeingif switching on p73 can translate into a treatment forpatients.” For media enquiries, please contact Emma Gilgunn-Jones in thepress office on 020...