Stomach in Medical Technology

Horizon Therapeutics' HZT-501 Significantly Reduces Incidence of NSAID-Induced Upper Gastrointestinal Ulcers in Patients With Mild-to-Moderate Pain

... increase the risk of developing ulcers in the stomach or intestine and the risk of developing ulcer ... will provide effective pain relief and reduce stomach acidity during the peak time of ulceration risk, ... Because the prostaglandins that protect the stomach are reduced, NSAIDs often cause ulcers in the ...

RAD001 Phase II Trial Results Positive in Patients with Advanced Gastric Cancer After Failure of One or More Prior Treatments

... Gastric cancer, commonly referred to as stomach cancer, was diagnosed in 21,500 Americans in 2008 ... (2) American Cancer Society. Detailed Guide: stomach Cancer. Available at : ... (4) American Cancer Society. Overview: stomach Cancer. Available at: ...

Horizon Therapeutics Announces Two Pivotal HZT-501 Phase 3 Trials Meet Primary Endpoints

... gastrointestinal damage, including ulcers of the stomach and duodenum," said Loren Laine, MD, professor of ... will provide effective pain relief and reduce stomach acidity during the peak time of ulceration risk, ... Since the prostaglandins that protect the stomach are reduced, NSAIDs often cause ulcers in the ...

Takeda's Investigational PPI TAK-390MR Demonstrated Higher Healing Rates Compared to Lansoprazole as the Severity of Erosive Esophagitis Grade Increased, a New Integrated Analysis Showed

... opens to allow food and liquids to enter the stomach and closes to keep acid and food in the stomach. ... as it should, or relaxes too often, it can allow stomach contents to enter the esophagus repeatedly. ... If the esophagus is continually exposed to stomach contents, damage to the lining of the esophagus ...

Mayo Clinic Discovery May Help Diabetic Gastric Problem

... ). Gastroparesis occurs when the stomach retains food for longer periods. When that food ... Because the passage of food out of the stomach becomes unpredictable, maintaining a proper blood ... Gastroparesis can cause pain, nausea, vomiting, stomach spasms and weight loss due to ...

BARACLUDE(R) (Entecavir) Treatment Resulted In Greater Viral Load Suppression Compared to Adefovir at 96 Weeks In Antiviral-Naive Adult Chronic Hepatitis B E-Antigen Positive Patients

... unusual muscle pain, have trouble breathing, have stomach pain with nausea and vomiting, feel cold -- ... for several days or longer, feeling sick to the stomach (nausea), or having lower stomach pain. Lactic ... BARACLUDE should be taken once daily on an empty stomach (at least two hours after a meal and two hours ...

Low Acid Coffee Backed By Scientific Research

... coffee provides symptom relief for those with stomach problems caused by their morning brew. Puroast(R) ... there are several million consumers who have stomach discomfort from coffee drinking, it's clear ... Puroast(R) Low Acid Coffee's effect on these stomach symptoms. "Our study asked consumers to brew ...

BARACLUDE(R) (entecavir) Data Continue to Demonstrate Low Incidence of Resistance Through Five Years of Treatment in Nucleoside-naive Chronic Hepatitis B Patients

... unusual muscle pain, have trouble breathing, have stomach pain with nausea and vomiting, feel cold ... for several days or longer, feeling sick to the stomach (nausea), or having lower stomach pain. Lactic ... BARACLUDE should be taken once daily on an empty stomach (at least two hours after a meal and two hours ...

Studies Show Body Mass Index Has No Effect on Resolution and Healing of GERD Symptoms

... with erosive esophagitis, a condition in which stomach acid wears away, or erodes, the inner lining of ... heartburn (a burning feeling, rising from the stomach or lower part of the chest towards the neck) two ... occurs when the valve between the esophagus and stomach does not close properly, allowing acid to leak ...

Current Status of the Development Programs of New Indications and Formulations for Aricept(R) for Enhancing Patient Value

... is well tolerated, but may not be for everyone. People at risk for stomach ulcers or who take certain other medicines should tell their doctors because serious stomach problems, such as bleeding, may get worse. Some people who take Aricept ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... warm, red, or painful skin or sores on your body diarrhea or stomach pain burning when you urinate or urinate more than normal ... clay-colored bowel movements fevers chills stomach discomfort skin rash If you take SIMPONI(TM) ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... warm, red, or painful skin or sores on your body diarrhea or stomach pain burning when you urinate or urinate more than normal ... clay-colored bowel movements fevers chills stomach discomfort skin rash If you take SIMPONI(TM) or ...

Colesevelam HCl Lowered LDL Cholesterol in Pediatric Patients With Heterozygous Familial Hypercholesterolemia

... triglycerides (greater than 300 mg/dL). Tell your doctor if you have stomach or intestinal problems, including gastroparesis (when the stomach takes too long to empty its contents), abnormal contractions of the ...

Consensus Document Outlines Practical Steps for Reducing Gastrointestinal Risks of Antiplatelet and NSAID Use

... and NSAIDs, which are both commonly used, and can cause erosions in the stomach lining," said Dr. Bhatt. "These recommendations represent the collective ... of H. pylori (a common bacteria that contributes to the development of stomach ulcers), dyspepsia or GERD (gastroesophageal reflux disease or "acid ...

First Ever Study on Alzheimer's Disease Treatment in Hispanics Presented at Major Medical Meeting

... ARICEPT is well tolerated, but may not be for everyone. People at risk for stomach ulcers or who take certain other medicines should tell their doctors because serious stomach problems, such as bleeding, may get worse. Some people who take ARICEPT ...

Device Blocking Stomach Nerve Signals Shows Promise in Obesity

... include "banding" -- placement of a band around the top part of the stomach to reduce its capacity -- or bypass procedures which reroute food and ... during the daytime hours so that the blocking signal can influence how the stomach functions and food is digested following a meal. The lead wires are ...

Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions

... the incidence of gastrointestinal side effects such as nausea and upset stomach were comparable to placebo patch. In the clinical trials, 3 percent of ... adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time ...

New York-Presbyterian/Weill Cornell is First New York Medical Center to Offer Tantalus Clinical Trial to Diabetes Patients

... Oral Anti-Diabetic Treatments Device Applies Electrical Stimulation to stomach as Person Eats NEW YORK, March 28 /PRNewswire/ -- New York-Presbyterian ... System is designed to sense naturally occurring electrical activity of the stomach in real time and automatically apply electrical stimulation when a person ...

PA Department of Health Reports Rise in Flu Activity; Reminds Public of Need for Flu Shot

... include fever, cough, headache, sore throat, muscle aches, fatigue and stomach symptoms, such as nausea, vomiting, and diarrhea. stomach symptoms are more common in children, but may also occur in adults. ...

Vanderbilt Medical Center Seeks Middle Tennesseans with Type 2 Diabetes Who are Overweight for National Clinical Trial

... System is an implantable device that delivers electrical pulses to the stomach when a person eats. The primary objective of the randomized, double-blind ... that is designed to sense naturally occurring electrical activity of the stomach in real time and automatically apply electrical stimulation treatment ...

LAP-BAND(R) System Weight-Loss Surgery Associated With More Than 70 Percent Reduced Risk of Death in People With Severe Obesity

... with severe and morbid obesity. Unlike gastric bypass, it does not involve stomach cutting, stapling or intestinal re-routing (9,10). Using laparoscopic ... top portion of the patient's stomach, creating a small pouch. By reducing stomach capacity, the LAP-BAND(R) System can help achieve long-term weight loss by ...

Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl)

... to check for liver problems before you start ACTOS and periodically thereafter. Talk to your doctor immediately if you experience nausea, vomiting, stomach pain, tiredness, loss of appetite, dark urine, or yellowing of the skin. If you are of childbearing age, talk to your doctor before taking ...

Meta-Analysis of Clinical Data Showed No Increased Risk of Cardiovascular Events Associated With Exenatide Use: Data Presented at ADA 2009

... requires insulin treatment. BYETTA is not recommended for use in patients with severe problems digesting food or those who have severe disease of the stomach or kidney. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To ...

Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009

... requires insulin treatment. BYETTA is not recommended for use in patients with severe problems digesting food or those who have severe disease of the stomach or kidney. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To ...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

... more common side effects with REMICADE are respiratory infections (that may include sinus infections and sore throat), headache, rash, coughing and stomach pain. Please read important information about REMICADE, including full U.S. prescribing information and Medication Guide, at ...

FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension

... intensity and included headache, muscle pain, flushing, nasopharyngitis, respiratory tract infection, nausea, pain in the arms, legs or back, upset stomach and nasal congestion. "Our dedicated team at United Therapeutics looks forward to working closely with the PAH community as we prepare to ...

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

... is a common problem affecting millions of Americans. Prilosec OTC and other proton pump inhibitors reduce the acidity (increase the pH) in the stomach and are commonly used by millions of adults in the United States who suffer from acid reflux. ADHD is estimated to affect 4.4 percent of US adults ...

Amylin and Lilly Announce Plans to Develop Pen Device for Exenatide Once Weekly

... requires insulin treatment. BYETTA is not recommended for use in patients with severe problems digesting food or those who have severe disease of the stomach or kidney. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To ...

American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought

... to be ineffective and unnecessarily expensive for some asthma patients who do not exhibit symptoms associated with acid reflux such as heartburn or stomach pain. Patients participating in the American Lung Association's ACRC study were randomly given either 80 milligrams of esomeprazole or placebo. ...

Torax Medical Launches Pivotal Clinical Study of New Acid Reflux Treatment

... by a defective lower esophageal sphincter, a ring-like muscular valve that surrounds the esophagus. When defective, it allows abnormal reflux of stomach acids and bile into the esophagus. Approximately 19 million adults in the U.S. suffer on a daily basis from the symptoms of GERD. Medical therapy, ...

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Announces FDA Filings for Paliperidone Palmitate and INVEGA(R)

... The connection between prolactin levels and side effects is unknown. People with narrowing or blockage of the gastrointestinal tract (esophagus, stomach or small or large intestine) should talk to their healthcare professional before taking paliperidone. Some people taking paliperidone may feel ...

Meritage Pharma Initiates Phase 2b Clinical Trial of Oral Viscous Budesonide for Pediatric Patients With Eosinophilic Esophagitis

... commonly have other allergic conditions such as asthma or eczema. Symptoms of EoE may include nausea, dysphagia (problems swallowing), vomiting, stomach pain, chest pain, heartburn, loss of weight, and food impaction. Other symptoms may include reflux that does not respond to proton pump inhibitor ...

AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R)

... of relationship to treatment, included nasopharyngitis, headache, upper respiratory tract infection, pharyngolaryngeal pain, sinusitis, and stomach discomfort. Please see full Prescribing Information and visit www.MySYMBICORT.com . Media Contacts US: ...

Plans for Exenatide Once Weekly NDA Submission by End of First Half of 2009 Reaffirmed Following FDA Feedback

... requires insulin treatment. BYETTA is not recommended for use in patients with severe problems digesting food or those who have severe disease of the stomach or kidney. When BYETTA is used with a medicine that contains a sulfonylurea, hypoglycemia (low blood sugar) is a possible side effect. To ...

Alexza's AZ-004 (Staccato(R) Loxapine) Meets Primary Endpoint of Treating Acute Agitation in Patients with Bipolar Disorder in Phase 3 Trial

... 2% Dry mouth 2% 2% 1% Nausea 2% 0% 1% stomach discomfort 2% 3% 1% Diarrhea 3% 1% 0% Skin rash ...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

... bleeding was the main safety parameter. In this study, 1,166 patients with advanced lung (279), colon (235), breast (165), ovarian (143), stomach (98), rectal (87), pancreatic (53), head and neck (36), and other cancers (54) were randomized to one of two treatment arms: once-daily subcutaneous ...

Photos: Peptides Discovered to Alleviate Chemotherapy Side Effects

... treatment impact," stated Dr. Tsai. In addition to stimulating SOD production, AminoAct(TM) also increases the secretion of ghrelin, a stomach hormone that stimulates appetite. According to the American Cancer Society, weight loss in the main cause of death for 1 in 5 cancer patients. "Our ...

Study Suggests Treatment with Paliperidone ER Significantly Improves Symptoms of Schizoaffective Disorder

... The connection between prolactin levels and side effects is unknown. People with narrowing or blockage of the gastrointestinal tract (esophagus, stomach or small or large intestine) should talk to their healthcare professional before taking paliperidone. Some people taking paliperidone may feel faint ...

Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD

... of relationship to treatment, including nasopharyngitis, headache, upper respiratory tract infection, pharyngolaryngeal pain, sinusitis, and stomach discomfort. Please see full Prescribing Information and visit http://www.MySYMBICORT.com . About AstraZeneca AstraZeneca is a major ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

... The most common side effects of REMICADE are: respiratory infections, such as sinus infections and sore throat, headache, rash, coughing and stomach pain. Please read important information about REMICADE, including full U.S. prescribing information and Medication Guide, at ...