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Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse

...d halfway houses for criminals may be regulated by state laws. They are generally acceptable for use in the office practice environment. Some home use drug testing kits are also being sold. These generally are not testing devices themselves, but are specimen containers which are to be filled and sent to a ...

Large Geographic Differences in EpiPen Prescriptions in the U.S., From the Journal of Allergy and Clinical Immunology

...04 for all 50 states andWashington, D.C. They used state populations to calculate theaverage number of prescriptions written per person. Researchers found that on average, there were 5.71 EpiPensprescribed per 1000 persons in the U.S. The highest number ofprescriptions per 1000 persons was in Massachuse...

Halozyme Therapeutics' Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society

...(PK) analysis used to estimate theeffect of steady state co-administration of rHuPH20 with theLPMT. This...elative SC bioavailability of adalimumab at steady state if co-injected with rHuPH20; thus, the reported reference 64% SC absolute bioavailabilit...

Molecular Target of Bradmer's Neuradiab Further Validated by Independent Findings

...t of 1933, as amended (the"Securities Act") or any state regulatory agency in the UnitedStates. The resale or transfer by a U.S. investor of such commonshares of Bradmer Pharmaceuticals Inc. is subject to therequirements of Rule 904 of Regulation S of the Securities Act orsuch other applicable exemption th...

Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections

... general economic factors, business strategies,the state of capital markets, regulatory conditions, and otherfactors not currently known to the company, may be significant, nowor in the future, and these factors may affect the company to agreater extent than indicated. All forward-looking statementsattribu...

Labopharm to Present Poster on Dose Titration of Once-daily Tramadol at 3rd International Forum on Pain Medicine

...m'sonce-daily tramadol formulation achieves steady state plasma levelsafter two days, suggest that a shorter titration schedule may beadequate for most patients. A previous study showed that mostpatients achieve pain control using Labopharm's once-daily tramadolat a dose of 200 mg. The data in this poster ...

Expert Opinion Highlights Avigen's AV411 as Potential New Therapeutic for Neuropathic Pain and Opioid Withdrawal

...nditions to treat. It is an extremely complex pain state that ismost often preceded by tissue injury, although the pain state cancontinue after the initial injury has healed. Nerve fibers may bedamaged, dysfunctional or injure...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

...ution The mean volume of distribution at steady state following a single100 mg intravenous dose of sitagliptin to healthy subjects isapproximately 198 liters. The fraction of sitagliptin reversibly boundto plasma proteins is low (38%). Metabolism Approximately 79% of sitagliptin is excreted unchan...

HepaLife's PBS-1 Cells for Influenza Vaccine Production Prove Superior at International Conference

...y of new competitors and products,adverse federal, state and local government regulation, inadequatecapital, unexpected costs and operating deficits, increases ingeneral and administrative costs, termination of contracts oragreements, technological obsolescence of the Company's products,technical problems ...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

...ution The mean volume of distribution at steady state following a single100 mg intravenous dose of sitagliptin to healthy subjects isapproximately 198 liters. The fraction of sitagliptin reversibly boundto plasma proteins is low (38%). Metabolism Approximately 79% of sitagliptin is excreted unchan...

Positive Clinical Results for DG041 Lead Product Development Highlights at deCODE R&D Event

...ASP),which normally holds platelets in a quiescent state whenphosphorylated but causes platelets to bind when dephosphorylatedupon activation of EP3, was found to provide such a biomarker. Thecompany thus began a clinical pharmacology study to examine DG041'seffectiveness in blocking VASP-mediated platelet...

AMIA Announces 2008 Summit on Translational Bioinformatics

...nd as a premier venue forreporting advances in the state of translational research." The summit will take place March 12-15, 2008 at the Hilton SanFrancisco in San Francisco, California. A call for participationand program will be announced in the near future. For moreinformation about AMIA's translationa...

Research on New Treatment for Neglected Disease Published in The New England Journal of Medicine

...ne carrying 50% of all new cases. Themost affected state in India is Bihar, but VL is also endemic inthe states of Jharkand, West Bengal, and Uttar Pradesh. About Paromomycin Phase 3 Clinical Trial The approval of Paromomycin IM Injection in India is based ondata from a large Phase 3 multi-center, random...

Array BioPharma Reports New Clinical Data on Its Anti-Inflammatory Drugs

...ranging from 5 to 60 mg daily, for 14 days. Steady state drugexposure was proportional to dose and did not change with repeateddosing. In volunteers receiving daily doses of 40 mg of ARRY-162,inhibition of 50 to 90 percent of IL-1beta, TNF-alpha, and IL-6 wasobserved when measured over a 24-hour period. Th...

Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure Reduction During Important Early Morning Period When Most Adverse Cardiovascular Events Occur

...ion: commonly known as a heart attack; is adisease state that occurs when the blood supply to a part of theheart is interrupted. Peptide: a fragment of a protein comprised of two or more aminoacids. Phase IIa: a clinical trial that examines a new drugcandidate’s safety and exploratory efficacy and ma...

Indevus Announces Presentation of Pagoclone Data at 47th Annual New Clinical Drug Evaluation Unit Meeting

...SANCTURAXR(TM), NEBIDO(R) and VANTAS(R); the early state of products underdevelopment; uncertainties relating to clinical trials, regulatoryapproval and commercialization of our products, particularlySANCTURA XR, NEBIDO, VALSTAR(R) and SUPPRELIN(R)-LA; risksassociated with contractual agreements, particula...

Treating Heart Disease Risk Factors May Slow Alzheimer's Disease Progression

...e by almost one third, according to themini-mental state evaluation (MMSE) score. "That means the patients whose vascular risk factors weretreated declined at a slower rate such that it took them threeyears to decline as much as untreated patients did after twoyears," Deschaintre said. "Most of the socia...

Clinical Update - Debio 9902 (ZT-1) for Alzheimer's Disease

...ent cognitive sub-scale (ADAS-cog), theMini mental state examination (MMSE) and the Neuropsychiatricinventory questionnaire (NPI-Q). The study included a randomizedpart which lasted 3 months and which was followed by an additional6 month open label part. The efficacy shown with the oralformulation, the goo...

ApoCell's Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy

...this study was derived by comparing thebiochemical state of a cancer cell receptor that is critical to theprocess of angiogenesis or vascularization of tumors. This PDxIndex(TM) of patients with head and neck cancer showed a directcorrelation between the drug regimen and patient response. This newtechnolog...

Indevus Reports Positive Data From Phase III NEBIDO Trial

...eragetestosterone concentrations during the steady state dosing intervaland an outlier analysis based on th...ximum testosteroneconcentrations during the steady state dosing interval. Inaddition, the drug was well tolerated. The Company will host aconference call and...

Arrowhead Subsidiary, Insert, Publishes Interim Phase I Data from Human Clinical Trials for New Cancer Drug

...hout disease progression." The abstract's authors state that the stable disease rate,although not yet conclusive, is consistent with promising efficacy.In general, IT-101 was well tolerated and pancytopenia was the doselimiting toxicity. Patients that have completed the six cycletreatment regimen and show...

HepaLife Announces Scientific Presentation of PBS-1 Cell Line at International Influenza Meeting

...y of new competitors and products,adverse federal, state and local government regulation, inadequatecapital, unexpected costs and operating deficits, increases ingeneral and administrative costs, termination of contracts oragreements, technological obsolescence of the Company's products,technical problems ...

Palatin Technologies and King Pharmaceuticals Report Data Showing Improvements in Sexual Relationship and Self-Esteem in Patients with Erectile Dysfunction Treated with Bremelanotide

...s incurrent pricing levels; changes in federal and state laws andregulations; changes in competition; unexpected changes intechnologies and technological advances; and manufacturing capacityconstraints. Other important factors that may cause actual resultsto differ materially from the forward-looking state...

Ulcerative Colitis (UC) Sufferers Find UC Quite Disruptive to Many Aspects of Daily Life

...r sexualrelations (75 percent) and their emotional state (82 percent). UC patients "normalize" aspects of their experience to the pointthat they resign themselves to these burdens. The majority say thatthere is not much they can do beyond what they are already doing tofeel better (70 percent) and they hav...

Sciele Pharma Announces Successful Completion of New Sular Formulation Clinical Trial Program

... may be foundnoncompliant with applicable federal, state or international laws,rules or regulations which could result in fines and/or productrecalls or otherwise cause us to expend significant resources tocorrect such non-compliance. A small number of customers accounts for a large portion of oursales an...

NicOx Provides an Update on the Phase 2a Study for NCX 1000 Conducted With Axcan

...onbetween patients' portal pressure in the fasting state on day 16 oftreatment with the corresponding baseline values. A secondaryendpoint was the same comparison following the consumption of acontrolled meal and additional endpoints were based on the responserate (defined in terms of portal pressure reduc...

Palatin Technologies and King Pharmaceuticals Announce Plan To Present Results of Bremelanotide Phase 2b Studies in Men With Erectile Dysfunction

...s incurrent pricing levels; changes in federal and state laws andregulations; changes in competition; unexpected changes intechnologies and technological advances; and manufacturing capacityconstraints. Other important factors that may cause actual resultsto differ materially from the forward-looking state...

Alba Therapeutics Corporation Reports Preliminary Phase IIa Clinical Trial Results for AT-1001 for the Treatment of Celiac Disease

...intestinal permeability (IP) --a marker of disease state in CD -- as well as patient symptoms andoutcomes, measured by two validated tests of gastrointestinaldisease outcome: the Gastrointestinal Symptoms Rating Scale (GSRS)and the Psychological General Well-Being Index (PGWBI). Preliminary analysis r...

Revolutionary Immunologic Data Explains Function of Diamyd Diabetes Vaccine

...us insulin production will bepreserved. Now we can state that the treatment may be relevant alsoat a later stage as the immunological effect observed may be aprerequisite to allow beta cell regeneration or transplanted isletsor stem cells to thrive without being destroyed by recurrentautoimmune attacks.&rd...

Quest PharmaTech's Prostate Cancer Program Update

...th a novel intra-arterial drug delivery system and state of theart laser device that delivers pulsed light. Pre-clinical studiesin small and large animals have demonstrated the effectiveness ofSL052 in selective destruction of normal and cancerous prostatetissues, with minimal side effects. The use of 18 F...

New Data Shows Once a Day Lamictal XR is Effective in Treating Patients with Partial Seizures

...g each treatment phase. Results showed the steady state trough concentrations forLamictal XR were equivalent to or higher than those of Lamictalimmediate release depending on concomitant AED. In addition, therewas no change in the median weekly seizure frequency among thegroups. ABOUT EPILEPSY Epilepsy,...

Pluristem to Present Two Scientific Posters at the International Society for Cellular Therapy

...100 biotechnologycompanies, academic institutions, state biotechnology centers andrelated organizations across the United States and 31 othernations. Mr. Aberman added, "These venues provide us with severalopportunities to interact with researchers, laboratoryprofessional, physicians, regulatory specialis...

Ties Between Physicians and Drug Companies Still Too Strong: the Prescription Project Offers Solutions to Prevent Conflicts of Interest

...ts and end data-mining are moving to the floors of state housesnationwide." -- Today, New York legislators...t industry gifts. -- Earlier this week, Minnesota state officials announced ajoint effort with consumers and health groups there to strengthenthe state's fi...

BDSI Announces Positive Phase III Clinical Trial Results for BEMA Fentanyl

... our stockholders, and our board takesthis time to state its appreciation and admiration of the effortsof our management team and all of our employees." Dr. O'Donnell continued, "We are hopeful that this demonstrationof the effectiveness of BEMA(TM) Fentanyl augers very well for thepotential application o...

Reata's Synthetic Triterpenoids Profiled in Nature Reviews Cancer

...haveprofound effects on inflammation and the redox state of cells andtissues, as well as being potent anti-...viewed journals.The article summarizes the current state of this literature. Somehighlights of this comprehensive body of research reviewed in thearticle inc...

Ceragenix Announces Results from Phase IV Study of EpiCeram Meet All Primary and Secondary Endpoints

...general economic factors, business strategies, the state of capitalmarkets, regulatory conditions, and other factors not currentlyknown to the company, may be significant, now or in the future, andthese factors may affect the company to a greater extent thanindicated. All forward-looking statements attribu...

Ceragenix Announces New Publication of Scientific Research on Ceragenin Technology

...general economic factors, business strategies, the state of capitalmarkets, regulatory conditions, and other factors not currentlyknown to the company, may be significant, now or in the future, andthese factors may affect the company to a greater extent thanindicated. All forward-looking statements attribu...

Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention

...represents more than 1,100biotechnology companies, state and international affiliates, andrelated organizations. BIO is widely known for the BIOInternational Convention, a four-day annual biotechnology showcasethat draws about 20,000 attendees. The convention serves to educatethe public and policymakers ab...

Costs of Eradicating Poliomyelitis Now Are Much Lower Than Trying to Control It Later

...sintensity could lead to large outbreaks—and state that moreshort term funds are needed than are currently being spent. The authors conclude: "Worldwide eradication ofpolioviruses is likely to yield substantial health and financialbenefits, provided we finish the job." In the second paper, Dr Nicho...

State of Diabetes in Pittsburgh: Pittsburgh Business Group on Health Releases Report

...dWheeling, West Virginia. The report also provides state andnational benchmarks that can help employers and providers betteridentify opportunities to serve the needs of people with Type 2diabetes. "PBGH developed the Pittsburgh Type 2 Diabetes Report to serveas a useful resource for employers in their eff...

Presentations at American College of Cardiology Meeting Highlight New Opportunities for HDL Therapy

...b Experience?"providing perspective on the current state of HDL Therapy and itsfuture potential. The full text of the article will be available onour website: <a target="_blank" href="http://www.lipidsciences.com/">www.lipidsciences.com at theLipid Sciences in the News heading. Lipid Sciences' HD...

Diabetes Linked to Higher Parkinson's Risk

...e mechanisms by which soy affects the inflammatory state maybe related to the effects of soy phytoestrogens, which mimichormone replacement therapy. However, more research needs to bedone to understand the mechanisms through which soy affectsinflammation and endothelial function. It is also unclear whether...

Alexza's AZ-004 Phase IIa Trial Meets Primary Endpoint in Treating Schizophrenic Patients With Acute Agitation

...ons regardingtheir treatment in an acute agitative state and would prefer anoninvasive treatment. Alexza also believes there is a significantunmet medical need for a faster-acting, noninvasive treatment ofacute agitation in schizophrenic patients. About AZ-004 (Staccato loxapine) AZ-004 is the combinatio...

Study: Identical Doses of BiDil Components Are Not Bioequivalent to the Fixed Dose Combination-BiDil-Used in A-HeFT

.... Unproven remedies should not be used in adisease state where 50% of the patients will die within 5 years,and 50% of severe HF patients will die within one year," hesaid. About BiDil BiDil was approved in June 2005 by the U.S. Food and DrugAdministration and is indicated for the treatment of heart fai...

Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm Formation in 21 Day Study

...general economic factors, business strategies, the state ofcapital markets, regulatory conditions, and other factors notcurrently known to the company, may be significant, now or in thefuture, and these factors may affect the company to a greaterextent than indicated. All forward-looking statements attribu...
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(Date:9/8/2008)...llan Nuclear Radiation Center (MNRC) in Sacramento... corrosion and defects in aircraft structure using...This technique is currently helping soil scientist... uptake of water and nutrients. , Scientists at ...lts from a newly developed non-invasive technique ...
(Date:9/8/2008)...y foods - bearded vultures do, too. A study by Ant...rotection Group in El Pont de Suert, Spain, has fo...rgy-dense bones and choose only the bones containi...n and delivery to its young. His findings will be ...ioral Ecology and Sociobiology . , The bearded v...
(Date:9/8/2008)...aded by Prof. Daniel Rosenfeld of the Institute of...lem, has come up with a surprising finding to the ...or decreases rainfall. The conclusion: both can be.... , The determination of this issue is one with...nge and specifically in areas suffering from manma...
(Date:9/8/2008)... "Smart water" may help boost production from oil...earchers in Norway report that injecting a special...n low-yield oil wells may help boost oil extractio...eet rising energy demands and provide consumers wi...ture, the scientists suggest. Their findings are s...
Breaking Biology News(10 mins):US Air Force technology helps scientists understand plant root function 2Scavenger birds chew the fat 2Dirty air brings rain -- then again, maybe not 2Dirty air brings rain -- then again, maybe not 3American Chemical Society's Weekly PressPac -- Sept. 3, 2008 2American Chemical Society's Weekly PressPac -- Sept. 3, 2008 3American Chemical Society's Weekly PressPac -- Sept. 3, 2008 4American Chemical Society's Weekly PressPac -- Sept. 3, 2008 5American Chemical Society's Weekly PressPac -- Sept. 3, 2008 6American Chemical Society's Weekly PressPac -- Sept. 3, 2008 7American Chemical Society's Weekly PressPac -- Sept. 3, 2008 8GANIC Pharmaceuticals Launched with Premier Pharmaceutical Industry Executives 6081 1GANIC Pharmaceuticals Launched with Premier Pharmaceutical Industry Executives 6081 2GANIC Pharmaceuticals Launched with Premier Pharmaceutical Industry Executives 6081 3HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point of Care Test for Microalbuminuria a Kidney and Cardiovascular D 6076 1HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point of Care Test for Microalbuminuria a Kidney and Cardiovascular D 6076 2HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point of Care Test for Microalbuminuria a Kidney and Cardiovascular D 6076 3HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point of Care Test for Microalbuminuria a Kidney and Cardiovascular D 6076 4HemoCue Receives First FDA CLIA Waiver in Diagnostics Industry for Quantitative Point of Care Test for Microalbuminuria a Kidney and Cardiovascular D 6076 5Best code for disease detection bar none 3677 1Invest in a future without dementia 22165 1Invest in a future without dementia 22165 2
(Date:9/5/2008)... -- EthicAd, a nonprofit organization,devoted to i... announces,the launch of a new FDA Web site create...ect-to-consumer (DTC) advertising of prescription,...n Drug Advertising," is,hosted by the FDA,s Center...d by the FDA in partnership with EthicAd. For deta...
(Date:9/5/2008)...lps reverse disease resistance to anti-hormonal th...s) -- The drug sorafenib may help "re-sensitize" c..., Georgetown University Medical Center researcher...terone-receptor positive (ER or PR positive) metas...cines, such as aromatase inhibitors, to keep the c...
(Date:9/5/2008)...iction models are enhanced by taking into account ...apacity, according to research teams led by epidem...n Cancer Center in two complementary papers appear...esearch . , In the first study to focus on Afric...ed on increased exposure to certain risks. Based u...
(Date:9/4/2008)...samples provided to physicians by pharmaceutical c...nts more in the long run, according to a study don... Medical Center and colleagues. , The retrospect... than 70 physicians in a university-affiliated int...before and after the closing of their drug sample ...
Breaking Medicine News(10 mins):Health News:Prescription Drug Advertising Subject of New FDA Web Site for Consumers 2Health News:Drug Re-Sensitizes Breast Tumors to Treatment 2Health News:Creating lung cancer risk models for specific populations refines prediction 2Health News:Creating lung cancer risk models for specific populations refines prediction 3Health News:Free drug samples may end up costing uninsured more 2Health News:Free drug samples may end up costing uninsured more 3
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