spectrum

Suven Life Sciences Presenting Pre-clinical data of their NCE’s SUVN-502 and SUVN-507at International Brain Research Organization (IBRO) 2007 World Congress of Neuroscience

...laborative research partners, ability tooffer full spectrum of services from discovery to market launch andprovide technologies and expertise in different therapeutic areas.Suven has R&D strength of more than 190 professionals with thestate of the art infrastructure for Drug Discovery and developmentactiv...

From Clinical Cancer Research: Rethinking Therapeutic Cancer Vaccine Trials

...orethan 70 other countries. AACR marshals the full spectrum ofexpertise from the cancer community to accelerate progress in theprevention, diagnosis and treatment of cancer through high-qualityscientific and educational programs. It funds innovative,meritorious research grants. The AACR Annual Meeting attract...

Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients

...orethan 70 other countries. AACR marshals the full spectrum ofexpertise from the cancer community to accelerate progress in theprevention, diagnosis and treatment of cancer through high-qualityscientific and educational programs. It funds innovative,meritorious research grants. The AACR Annual Meeting attract...

Researchers Discover Method for Identifying How Cancer Evades the Immune System

...orethan 70 other countries. AACR marshals the full spectrum ofexpertise from the cancer community to accelerate progress in theprevention, diagnosis and treatment of cancer through high-qualityscientific and educational programs. It funds innovative,meritorious research grants. The AACR Annual Meeting attract...

Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis

...ily of transcriptionalfactors that regulate a wide spectrum of genes critically involvedin host defence and inflammation. The mechanism of action ofHMPL-004 was further supported in inflammatory bowel diseasepre-clinical models. Treatment of inflammatory bowel disease ratswith HMPL-004 caused a significant dr...

New Research Demonstrates Broad Efficacy of Azixa (MPC-6827) Against Multiple Tumor Types and in Drug Resistant Cell Lines

...ficant activity in inhibiting the growth ofa broad spectrum of solid tumor lines in athymic nude mice,including human breast, colon, pancreas, ovarian and mousemelanoma. Additional in vitro studies demonstrated that MPC-6827exerts its effects by binding of tubulin, thereby inhibitingpolymerization and leading...

Indevus Reports Positive Data From Phase III NEBIDO Trial

... the persistencewith study treatment. Further, the spectrum of adverse eventsreported were comparable to other injectable hypogonadismtreatments reported in the literature. There were no significantadverse changes in laboratory parameters with NEBIDO treatment. Conference call and webcast The Company will h...

Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA Nanoparticles

...aculardegeneration, Usher syndrome, and the entire spectrum of retinaldegenerative diseases. Visit www.FightBlindness.org for moreinformation on the Foundation's efforts. Contact Copernicus Therapeutics, Inc. Robert C. Moen, M.D., Ph.D., 216-231-0227 x26 President & CEO or Mark J. Cooper, M.D., 216-231-...

CytImmune Presents Positive CYT-6019 Data During the American Society of Clinical Oncology Annual Meeting in Chicago

...tile therapeutic which may be used to treat abroad spectrum of solid tumors." CYT-6091 (Aurimune), CytImmune's lead drug compound, isrecombinant human tumor necrosis factor alpha (TNF) bound to thesurface of 27 nanometer PEGylated colloidal gold nanoparticles.While TNF's tumor killing properties are well d...

EntreMed's Aurora Kinase Inhibitor Induces Tumor Regression in Preclinical Models

...ly, ENMD-981693 demonstratedpotent inhibition of a spectrum of targets linked to angiogenesis,including KDR (VEGFR2) and FGFR1. The compound was also shown toinduce apoptosis and cell cycle arrest in a broad range of celllines. ENMD-981693 exhibited antiangiogenic activity in in vivo animalmodels by preven...

Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax

...apid in vitrobactericidal activity against a broad spectrum of seriousgram-positive pathogens, including multi-resistant strains.Oritavancin's multiple targets and mechanisms of action workagainst the development of resistant strains, which is importantwhen treating serious gram-positive infections. To date, ...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

...ary goalof depression treatment. Treating the full spectrum of emotionaland physical symptoms to remission significantly decreases apatient’s risk of relapse. 14 Eli Lilly and Company and Boehringer Ingelheim In November 2002, Eli Lilly and Company and Boehringer Ingelheimsigned a long-term agreemen...

Pro-Pharmaceuticals to Present Abstract at the International Society of Oncodevelopmental Biology and Medicine Conference

...(R)). Results show thatDAVANAT(R) exhibits a broad spectrum of activity with tested drugs.The Company is developing additional carbohydrate-based therapeuticcompounds that are currently in the pre-clinical stage ofdevelopment. Founded in 2000, the Company is headquartered inNewton, Mass. Additional informatio...

Samaritan Announces Positive Data in Nonclinical (IND) In-Vitro Studies for Promising Alzheimer's Drug

...y preferred topreclinical when discussing the full spectrum of in-vitro andnon-human in-vivo tests associated with drug development. Bystudying a drug's dose-response characteristics, adverse andresidual effects, Samaritan and the FDA gain valuable insights, asto a drug's probable action, and effect in humans...

CEL-SCI's Cel-1000 Shown to Significantly Enhance Immune Response Against Hepatitis B Antigen in Animals

...type(cellular) immune responses to induce a broad- spectrum protectionagainst infection in animal models. The innate immune system isgenerally accepted to be the first line of defense againstinfectious agents. CEL-1000, derived from the beta chain of human MHC-II, is amodified version of a human immune-based...

Human Genome Sciences Reports Growing Evidence That Its TRAIL Receptor Antibodies Have Significant Potential in the Treatment of a Broad Range of Cancers

...eceptor antibodies are active incombination with a spectrum of conventional or novel therapeuticagents, including chemotherapy, radiation and proteosomeinhibitors. Both HGS-ETR1 and HGS-ETR2 are currently beingevaluated in clinical trials in a variety of human tumors. In a separate poster presentation, resul...

Affymax Announces Phase 2 Clinical Trial Results of Once-Per-Month Hematide for the Treatment of Anemia in Patients with Early- and End-Stage Chronic Kidney Disease

...ropriate managementof hemoglobin levels in a broad spectrum of patients with CKD fromearly-stage patients not on dialysis to patients with end-stagerenal disease requiring continuous dialysis support," said Dr.Macdougall. "Anemia is a pervasive problem in the chronic kidneydisease patient population. Being ab...

Othera Pharmaceuticals Announces Upcoming Presentation Based Upon Expanded Understanding of Lead Compound Mechanism of Action

...nical sideeffect. "We were impressed by the broad spectrum effect of Othera'scompounds in terms of their ability to inhibit not only genesinvolved in oxidative stress responses, but also inflammatoryresponse genes that control angiogenesis," said Dr. Mousa. "Theseclues pointed us towards a more complex mecha...

Kosan Presents Preclinical Data on Nuclear Export Inhibitors, Novel Anticancer Agents, at AACR

...to work additivelyand synergistically with a broad spectrum of cancer chemotherapiessuch as DNA-damaging agent...as NEIs are synergistic when combined with a broad spectrum of cancer therapeutics in in vitro experiments. -- Abstract 5597: "Anti-Tumor Activity of ...

Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention

...earch onthe potential of lipohexapeptides as broad spectrum anti-infectivesin the prevention of wound infections caused by multiple-resistanthard to treat pathogens such as Pseudomonas aeruginosa in burns,Staphylococcus aureus in surgical wounds and Acinetobacterbaumannii in trauma wounds. The company's lipoh...

Cequent Pharmaceuticals Founder to Present tkRNAi Technology at the American Association of Cancer Research Annual Meeting in Los Angeles

...orethan 70 other countries. AACR marshals the full spectrum ofexpertise from the cancer community to accelerate progress in theprevention, diagnosis and treatment of cancer through high-qualityscientific and educational programs. It funds innovative,meritorious research grants. The AACR Annual Meeting attract...

ANA380 Exhibits Activity In Vitro Against Multiple Clinically Relevant Hepatitis B Virus Mutants

... studies. "This study illustrates the promising spectrum of antiviralactivity for ANA380 against a defined ...ot limited to, references to thebelieved potential spectrum of activity of ANA380/LB80380 against adefined panel of genetically defined drug-resistant HBV varia...

Hana Biosciences Announces Data to be Presented On Talvesta (Talotrexin) for Injection at The American Association for Cancer Research Annual Meeting

...emonstrated enhanced antitumor activity in a broad spectrum ofpreclinical studies by targeting the enzyme DHFR to prevent DNAsynthesis in tumor cells and inhibit tumor growth. These studiessuggest that Talvesta, as compared to methotrexate, enters intocells up to ten times more efficiently and demonstrates 10...

Eurand Announces Positive Phase III Clinical Study Results

...r phase III studiessupporting Zentase for the full spectrum of cystic fibrosispatients suffering from EPI, including those needing limitedsupplementation to those with very aggressive enzyme deficiency,"said Gearoid Faherty, Eurand Chairman and CEO. Zentase met all primary and secondary endpoints in two phas...

Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

...tance invitro and exhibits activity against a wide spectrum of bacteriathat cause many hospital and community-...savuconazole Isavuconazole has a potent and broad spectrum of activityagainst both yeasts and molds. This new triazole is developed as awater-soluble pro-drug ...

REACH Registry Demonstrates That Multiple Arterial Disease Locations Sharply Increase the Risk of Major CV Events in Outpatients With Atherothrombosis

...nvestigators. The REACH Registry includes a broad spectrum of patients withatherothrombosis - documenting the...world event rates and treatment patterns in abroad spectrum of patients with atherothrombosis worldwide. Theregistry follows more than 60,000 patients over 4 ye...

In New Study, Duloxetine Reduced Non-specific Pain and Emotional Symptoms Associated with Depression

...arygoal of depression treatment. Treating the full spectrum ofemotional and physical symptoms to remission decreases apatient’s risk of relapse.6 Eli Lilly and Company and Boehringer Ingelheim In November 2002, Eli Lilly and Company and Boehringer Ingelheimsigned a long-term agreement to jointly develo...

ArQule Announces Acceptance of Clinical Data on ARQ 197, c-Met Inhibitor, for Oral Presentation at ASCO

...et, with selective antitumor properties in a broad spectrum ofhuman cancer cells -- Broad spectrum anti-cancer activity of ARQ 197, a highlyselective oral c-Met Inhibitor, in multiple xenograft model...

Researchers Use Poliovirus to Destroy Neuroblastoma Tumors in Mice

...orethan 70 other countries. AACR marshals the full spectrum ofexpertise from the cancer community to accelerate progress in theprevention, diagnosis and treatment of cancer through high-qualityscientific and educational programs. It funds innovative,meritorious research grants. The AACR Annual Meeting attract...

Newly Released Canadian Data Links Vaccines with Pervasive Developmental Disorder

...ccines may play a role in the development ofautism spectrum disorders. David Ayoub, MD presented datasuggesting a correlation between mercury- containing vaccines andrates of pervasive developmental disorder (PDD), a form of autism,in Montreal. The peak rate of one in 87 children diagnosed with PDDoccurred fo...

Replidyne Phase II Pediatric Trial Meets Primary Objective

...y and tolerability profiles,as well as their broad spectrum of activity, and as a result areoften used as first line therapy in many respiratory and skininfections in adult and pediatric patients. About Acute Otitis Media Acute otitis media (AOM) is the most frequent pediatricbacterial infection that result...