Serum in Medical Technology

Spherix Announces Positive Phase 2 Study Results

... 2 trial, Naturlose also decreased the average serum triglycerides of the patients by -59 mg/dl by the ... 6 months of the trial. Naturlose also decreased serum LDL by an average -13 mg/dl by the end of the first month on therapy, while serum HDL was essentially unchanged (+0.9 mg/dl). The ...

Glycerin Proven to Improve Bruising and Swelling Caused By Trauma to Skin

... post-procedural application of Bruise Relief(TM) serum versus a placebo. The product was found to reduce ... Bruise Relief(TM), available in a gel or serum formulation, also contains vitamins, nutrients ... a topical skin care product in a gel and serum formulation designed to eliminate the appearance ...

Another Study Links Fluoride to Bone Cancer

... young adults. Randhu and colleagues measured serum fluoride levels in three equal groups of ... three had musculo-skeletal pain.(1) "Mean serum fluoride concentration was found to be ... proves a link between raised fluoride levels in serum and osteosarcoma," they write. This ...

First Human Study to Show 'Sun Chlorella A' Supports Heart Health

... in noticeable reductions in body fat percentage, serum total cholesterol, and fasting blood glucose ... had a decrease in body fat percentage and total serum cholesterol. However, the high-risk group also ... women in the U.S. Risk factors include elevated serum cholesterol, high blood pressure, a sedentary ...

Cancer Research 'David' Hopes to Slay 'Cancer Goliath'

... a biological agent resulting from a pre-treated serum injected into a particular large animal. The serum causes the animal's system to create an ... breast cancer. (The injected pre-treated serum into the large animal appears to give the animal ...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

... to their occurrence. Elevated serum lipase Caution is recommended in patients with history of pancreatitis. Check serum lipase periodically. Liver function abnormality serum bilirubin and hepatic transaminases The use ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... to their occurrence. Elevated serum lipase Caution is recommended in patients with history of pancreatitis. Check serum lipase periodically. Liver function abnormality serum bilirubin and hepatic transaminases The use ...

FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder

... with PROMACTA must have regular monitoring of serum liver tests (see Laboratory Monitoring ... then cautiously reintroduce PROMACTA and measure serum liver tests weekly during the dose adjustment ... of PROMACTA. Liver tests: Monitor serum liver tests (ALT, AST, total and fractionated ...

New Data Show In Vitro Potency of Doripenem Against Resistant Bacteria

... as clinically indicated. Carbapenems may reduce serum valproic acid concentrations to subtherapeutic levels, resulting in loss of seizure control. serum valproic acid concentrations should be monitored ... or anticonvulsant therapy should be considered if serum valproic acid concentrations cannot be maintained ...

InVitria's Cellastim Showcased in Nature Article

... ) Cellastim (recombinant human serum albumin) was an effective replacement to bovine serum albumin in ES-cell culture. The article ... a recombinant albumin in place of animal-derived serum to eliminate contaminants in the cell culture. ...

FDA Requires Additional Information on DORIBAX for Treatment of Hospital-Acquired Pneumonia

... as clinically indicated. Carbapenems may reduce serum valproic acid concentrations to subtherapeutic levels, resulting in loss of seizure control. serum valproic acid concentrations should be monitored ... or anticonvulsant therapy should be considered if serum valproic acid concentrations cannot be maintained ...

New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma

... and chest pain have been observed with TORISEL. serum glucose, serum cholesterol and triglycerides should be ... elevated alkaline phosphatase (68%), elevated serum creatinine (57%), lymphopenia (53%), ...

New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer

... and chest pain have been observed with TORISEL. serum glucose, serum cholesterol and triglycerides should be ... elevated alkaline phosphatase (68%), elevated serum creatinine (57%), lymphopenia (53%), ...

Wyeth Initiates INTORACT -- A New Clinical Trial to Examine TORISEL Plus Avastin for First-Line Treatment of Advanced Kidney Cancer

... and chest pain have been observed with TORISEL. serum glucose, serum cholesterol, and triglycerides should be tested ... elevated alkaline phosphatase (68%), elevated serum creatinine (57%), lymphopenia (53%), ...

Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594

... elucidated the mechanism by which RDEA594 lowers serum uric acid levels. RDEA594 exhibits a ... effects are believed to result in the lowering of serum uric acid observed with RDEA806. URAT1 is ... significant, exposure-dependent, decreases in serum uric acid of 35% to 50% observed following 10-14 ...

Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting

... have contributed to their occurrence. Elevated serum lipase: Caution is recommended in patients with history of pancreatitis. Check serum lipase periodically. Liver function abnormality serum bilirubin and hepatic transaminases: Tasigna may ...

Shire Strives to Increase Adherence Among Chronic Kidney Disease Stage 5 Patients

... assistance with the complications of elevated serum phosphorus," said Joseph Schlitz, vice president, ... has shown that for each mg/dL increase in mean serum phosphorus, the relative risk of death increases ... FOSRENOL FOSRENOL is indicated to reduce serum phosphate in patients with end-stage renal ...

Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout

... Significant, Dose-Dependent Reduction in serum Uric Acid in Phase 1 Clinical Study - Phase 2 ... exposure-dependent reduction in serum uric acid (SUA). In the dose group that resulted ... results by dose group. Effect of RDEA806 on serum Uric Acid (SUA) Levels in Phase 1 MAD Study ...

Wyeth's TORISEL Receives European Commission Approval for the Treatment of Advanced Kidney Cancer

... and chest pain have been observed with TORISEL. serum glucose, serum cholesterol, and triglycerides should be ... elevated alkaline phosphatase (68%), elevated serum creatinine (57%), lymphopenia (53%), ...

Powerful New Efficacy Data in Moderate and Severe Hypertensive Patients Supports FDA Approval of AVALIDE(R) (Irbesartan-Hydrochlorothiazide) as the First Combination Therapy for Initial Use in Patients Likely to Need Multiple Drugs to Achieve Their Blood

... of diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in ... as measured by the occurrence of doubling of serum creatinine or end-stage renal disease (need for ... In patients with proteinuria, monitor serum potassium -- In placebo-controlled hypertension ...

The New England Journal of Medicine Publishes First Clinical Results for MedImmune's Chitinase-like Protein YKL-40 in Patients With Asthma

... Journal of Medicine suggest that circulating serum levels of YKL-40, also known as HcGP-39, are ... asthma, this new study evaluated the serum levels of related chitinase- like protein YKL-40 ... Data from this early-phase study suggest that serum YKL-40 levels were significantly elevated in ...

Study Shows VAPRISOL(R) is Effective in Increasing Serum Sodium Levels and Well-Tolerated in Patients With Euvolemic or Hypervolemic Hyponatremia

... hydrochloride injection) effectively raises serum sodium concentration ([Na+]) and ... that VAPRISOL can safely and effectively raise serum sodium levels in patients with underlying ... This effect, known as "aquaresis," increases serum sodium levels and helps to restore salt and water ...

Synvista Therapeutics' Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications

... ability of its compound, alagebrium, to reduce serum levels of advanced glycated end-products (AGEs) ... that diabetes resulted in an accumulation of serum AGEs and that there was a 50% reduction in ... study, late administration of alagebrium reduced serum AGEs to control levels and also restored nNOS ...

Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer

... and kidney functions, including transaminases and serum creatinine, should be performed in patients ... with concomitant thrombocytopenia, elevation of serum bilirubin, serum creatinine, blood urea nitrogen, or LDH). If this ...

Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia

... study, VAPRISOL showed a significant increase in serum sodium concentrations in patients with ... that VAPRISOL 40 mg/day significantly increased serum [Na+] in patients with euvolemic or ... This effect, known as "aquaresis," increases serum sodium levels and helps to restore salt and water ...

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

... 3-month injectable formulation, prescribed for a reversible reduction of serum testosterone to the level of castration in adult men suffering from sexual ... demonstrated a good efficacy and safety profile. Triptorelin decreased serum testosterone to the level of castration in all patients. Concurrent with ...

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

... 3-month injectable formulation, prescribed for a reversible reduction of serum testosterone to the level of castration in adult men suffering from sexual ... demonstrated a good efficacy and safety profile. Triptorelin decreased serum testosterone to the level of castration in all patients. Concurrent with ...

Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009

... was significantly reduced, with patients losing an average of 5.8 pounds. serum lipid profiles were significantly improved, and there was a significant ... of treatment, body weight was significantly reduced [-5.8+/-1.2 pounds], serum lipid profiles were significantly improved [total cholesterol -8.6+/-2.8 ...

Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes

... to placebo in reducing key measures of glycemic control, including fasting serum glucose and hemoglobin A1C (HbA1C). In this study, LY2189265 showed an ... in HbA1C; additional endpoints evaluated included changes in fasting serum glucose, solid mixed meal glucose excursion and body weight. For all ...

Prometheus Announces New Findings Regarding Patients at Risk for Celiac Disease at DDW

... 5,406 patients at risk for celiac disease who are EMA positive. Blood and serum samples were analyzed using PROMETHEUS(R) Celiac PLUS and PROMETHEUS(R) ... between the original and repeat tests; median changes in biomarker serum concentrations ranged between 2.2 EU/mL and 4.3 EU/mL. These results are ...

Investigational Genetic Test May Help Address Common Problems in Prostate Cancer Diagnosis

... the probability of a positive initial prostate biopsy in men with elevated serum PSA levels. In addition, PCA3 scores were higher in men whose prostate ... prostate cancer volume but no correlation to total prostate volume or serum Prostate Specific Antigen." Felix K h Chun, et al. (3) AUA poster ...

Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy

... therapy (IADT) in patients with advanced prostate cancer who have rising serum PSA levels after previous curative therapies. The study will compare IADT ... or induration), hot flashes, increased weight, fatigue, and increases in serum levels of transaminases and gamma-glutamyltransferase (GGT). Ninety-nine ...

DaVita Abstracts Accepted Into National Kidney Foundation's 2009 Spring Symposium

... Inc., Warren, MI -- Title: Mortality of 5-Year Time-Averaged Low serum Calcium <8.5 mg/dL in Subgroups of Hemodialysis (HD) Patients ... VA; and (3)DaVita Inc, El Segundo, CA -- Title: Association of serum Alkaline Phosphatase and Coronary Artery Calcification in ...

Phase III Trial Showed Investigational Compound Arzoxifene Was Superior to Evista(R) (raloxifene HCl) in Increasing BMD in Postmenopausal Women with Osteoporosis

... hip and femoral neck, and at suppressing bone turnover as assessed by serum markers of bone metabolism. In this study of 320 patients, more women ... objectives included assessment of femoral neck and total hip BMD, serum bone turnover markers, mammographic breast density and safety.(1) The ...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... allergic reactions have been reported. Clinically significant serum concentrations have been reported in some patients treated with Vancocin ... renal clearance of vancomycin are reduced in the elderly. Monitoring of serum concentrations may be appropriate in patients with renal insufficiency ...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

... based on calculated creatinine clearance. Before each Zometa dose, serum creatinine should be measured and treatment should be withheld for renal deterioration until serum creatinine has returned to within 10% of the baseline value. Zometa ...

Pieris Reports Development Progress for Anticalin(R) PRS-050, a Next Generation VEGF Antagonist

... engineering to balance their favorable tissue penetration with adjustable serum half-life. Moreover, Anticalins have been developed as Duocalins(R), whose ... endothelial growth factor (VEGF) in cancer. Optimised for extended serum half-life, PRS-050 exhibits comparable binding and functional in vitro ...

Transgenomic and Power3 Medical Complete Agreement for Exclusive License of Neurodegenerative Biomarker Test

... by Power3 Medical to monitor the concentration of a panel of blood serum protein biomarkers, using biostatistical analysis to assign a probability ... to complete phase II and III clinical validation trials of its blood serum diagnostics for Alzheimer's disease (AD-NuroPro), in the third quarter of ...

Breakthrough in Prenatal Screening for Down Syndrome

... while preserving the safety of mother and fetus. The maternal serum test developed by Lenetix medical director Dr. Stephen A. Brown at the ... H. Kellner. "Such breakthroughs in improvements of current maternal serum screening for fetal aneuploidy, including fetal Down syndrome, will lead ...

GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP

... Patients receiving therapy with PROMACTA must have regular monitoring of serum liver tests (see Laboratory Monitoring below). Discontinue PROMACTA if ALT ... the tests within 3 to 5 days. If the abnormalities are confirmed, monitor serum liver tests weekly until the abnormality(ies) resolve, stabilize, or ...