serotonin

EPIX Pharmaceuticals Presents Findings from PRX-00023 Phase 3 Clinical Trial at 47th Annual NCDEU Meeting

...epdisturbances typically associated with selective serotonin reuptakeinhibitors (SSRIs) and serotonin noradrenaline reuptake inhibitors(SNRIs), lacks the addictive and sedative effects of thebenzodiazep...

Frova Phase III Study Data Demonstrates That Short-Term Prevention Treatment Reduces Frequency and Severity of Menstrual Migraine

...nt,particularly during combined use with selective serotonin reuptakeinhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors(SNRIs). If concomitant treatment with FROVA and an SSRI (e.g.,flu...

International Movement Disorder Specialists Receive New Information About the Use of Once-Daily Azilect in the Treatment of Parkinson's Disease

...aking antidepressants.Seeing this apparent lack of serotonin toxicity is important." According to the US prescribing information the exposure duringdevelopment, both in dose and number of subjects was not adequateto rule out the possibility of an untoward reaction from combiningAZILECT with antidepressants. O...

Dynogen's DDP733 Reduces Reflux in Phase 1b GERD Study

...008. DDP733 is an oral, partial agonist of the serotonin type 3receptor (5-HT3), which Dynogen is developin... DDP733 DDP733 is an oral, partial agonist of the serotonin type 3receptor (5-HT3). Serotonin is a neurotransmitter that isknown to be involved in the control ...

Dynogen Reports Positive Results in Phase 1B GERD Study

...in 2008. DDP733 is an oral, partial agonist of the serotonin type 3receptor (5-HT(3)), which Dynogen is develop... DDP733 DDP733 is an oral, partial agonist of the serotonin type 3receptor (5-HT(3)). Serotonin is a neurotransmitter that is knownto be involved in the control...

XTL Provides Update on Phase I Clinical Trial of XTL-2125

...in and hepatitis C. XTL isdeveloping Bicifadine, a serotonin and norepinephrine reuptakeinhibitor, for the treatment of neuropathic pain. XTL is alsodeveloping several novel pre-clinical hepatitis C small moleculeinhibitors. XTL also has an active in-licensing and acquisitionprogram designed to identify and ac...

Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study

...tudy directly compared Cipralex® (anallosteric serotonin reuptake inhibitor - ASRI) to duloxetine (aserotonin and noradrenaline reuptake inhibitor - SNRI) and alsodemonstrated that Cipralex® was better tolerated, with fewerpatients discontinuing treatment with Cipralex® due to adverseevents compare...

Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression

... studydirectly compared Cipralex(R) (an allosteric serotonin reuptakeinhibitor - ASRI) to duloxetine (the most recently introducedserotonin and noradrenaline reuptake inhibitor - SNRI) and thesefindings support the growing body of evidence that Cipralex(R)offers important treatment advantages over SNRI antidep...

Antidepressant Use May Boost Fracture Risk, From Harvard Women's Health Watch

...who regularly tookantidepressants called selective serotonin reuptake inhibitors(SSRIs) had double the rate of fractures as people not using suchmedications. Other research points to depression itself as a sourceof endocrine changes that can damage bone. Whether the danger comes from depression, the drugs use...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

...onded onlypartially, to treatment with a selective serotonin reuptakeinhibitor (SSRI), regardless of whether th...s is not fullyknown, it is believed to affect both serotonin andnorepinephrine/noradrenaline mediated nerve signalling in the brainand the spinal cord. Based on ...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study for Milnacipran as a Treatment for Fibromyalgia Syndrome

...st of a new class of agents known asnorepinephrine serotonin reuptake inhibitors, or NSRIs, whichexerts its effect by preferentially inhibiting the reuptake ofnorepinephrine over serotonin, two neurotransmitters known to playan essential role in regulating pain and mood. It has been approvedfor the treatment o...

Alterations in Intestinal Serotonin in Irritable Bowel Syndrome and Dyspepsia

...linic researchers set out to determine the role of serotonin inpatients with IBS and dyspepsia. The study invol...from the stomach and intestines of eachpatient and serotonin levels were measured. Researchers found thatpatients with dyspepsia had low levels of a serotonin re...

Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder

...tine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine that is believed to potentiate t...erception, may be due to increasingthe activity of serotonin and norepinephrine in the central nervoussystem. Cymbalta is approved in the United States for the ...

Wyeth Presents Phase 3 Data for Pristiq, an Investigational Non-Hormonal Therapy for Menopausal Hot Flashes and Night Sweats

...tiq is believed to work by affecting thebalance of serotonin and norepinephrine. These chemicals, known asneurotransmitters, are thought to play an important role in thebrain to regulate body temperature and, during menopause may becomeimbalanced leading to hot flashes and night sweats. Wyeth filed a New Drug...

Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain

...tine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine that is believed to potentiate t... symptoms, may be due toincreasing the activity of serotonin and norepinephrine in thecentral nervous system. Cymbalta is approved in the United States for the ...

In New Study, Duloxetine Reduced Non-specific Pain and Emotional Symptoms Associated with Depression

...t Duloxetine Duloxetine is believed to impact both serotonin andnorepinephrine/noradrenaline mediated nerve sig...tine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine/noradrenaline. While the mechanism of action ofduloxetine in humans is not fully k...

Stanford Study Finds No Conclusive Benefit From Treating Kleptomania With Medication

...gs to a class of antidepressants known asselective serotonin reuptake inhibitors, and earlier studies havesuggested that SSRIs can be effective in treating some impulsecontrol disorders, such as skin picking. In an earlier, non-blindedopen-label phase of the kleptomania study, when trial participantswere aware...