reuptake

EPIX Pharmaceuticals Presents Findings from PRX-00023 Phase 3 Clinical Trial at 47th Annual NCDEU Meeting

...takeinhibitors (SSRIs) and serotonin noradrenaline reuptake inhibitors(SNRIs), lacks the addictive and sedative effects of thebenzodiazepines, and does not have the slow onset, short half-life,and side effects of a chemical class of 5-HT1A agonists calledazapirones. PRX-00023 is the subject of a composition o...

Frova Phase III Study Data Demonstrates That Short-Term Prevention Treatment Reduces Frequency and Severity of Menstrual Migraine

...takeinhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors(SNRIs). If concomitant treatment with FROVA and an SSRI (e.g.,fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram,escitalopram) or SNRI (e.g., venlafaxine, duloxetine) is clinicallywarranted, careful observation of the patient is a...

Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study

...tly compared Cipralex® (anallosteric serotonin reuptake inhibitor - ASRI) to duloxetine (aserotonin and noradrenaline reuptake inhibitor - SNRI) and alsodemonstrated that Cipralex® was better tolerated, with fewerpatients d...

Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression

...ost recently introducedserotonin and noradrenaline reuptake inhibitor - SNRI) and thesefindings support the growing body of evidence that Cipralex(R)offers important treatment advantages over SNRI antidepressantssuch as duloxetine(2-6). Depression is a serious illness that results in significantdisability an...

Antidepressant Use May Boost Fracture Risk, From Harvard Women's Health Watch

...rly tookantidepressants called selective serotonin reuptake inhibitors(SSRIs) had double the rate of fractures as people not using suchmedications. Other research points to depression itself as a sourceof endocrine changes that can damage bone. Whether the danger comes from depression, the drugs used totreat...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

...ommonly referred to asserotonin and norepinephrine reuptake inhibitors(SNRI) 5 , is approved in more than 70 c...inical studies, duloxetine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine/noradrenaline. Scientists believe its effect on painpercept...

Study Suggests Strattera Improved ADHD Symptoms in Patients With Comorbid Alcohol Abuse

...t Strattera Strattera, a selective norepinephrine reuptake inhibitor, is thefirst FDA-approved non-stimulant to treat ADHD in children,adolescents and adults. Since its first approval in the UnitedStates in 2002, more than 4.2 million patients have taken Stratteraworldwide. It has been studied in more than 6...

Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant

...tric Association. Paroxetine, a selectiveserotonin reuptake inhibitor (SSRI), is an antidepressant known tointeract with several antipsychotic medications. This new studyshowed there was no clinically significant increase in paliperidoneexposure when paroxetine was administered with paliperidoneER.(1) Many m...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study for Milnacipran as a Treatment for Fibromyalgia Syndrome

...w class of agents known asnorepinephrine serotonin reuptake inhibitors, or NSRIs, whichexerts its effect by preferentially inhibiting the reuptake ofnorepinephrine over serotonin, two neurotransmitters known to playan essential role in regulating ...

New Study Results Provide Additional Data about Short- and Long-Term Use of Desvenlafaxine Succinate in the Treatment of Adults with Major Depressive Disorder

...xine Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor(SNRI) studied as a potential treatment for adult men and womenwith MDD. Wyeth submitted a New Drug Application (NDA) for MDD onDecember 22, 2005. The Company also has filed an NDA for vasomotorsymptoms (VMS) associated with menopause and ex...

Pooled Studies Showed Desvenlafaxine Succinate Significantly Improved Painful Symptoms and Anxious Symptoms Associated with Major Depressive Disorder in Adults, Compared With Placebo

...xine Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor(SNRI) studied as a potential treatment for adult men and womenwith MDD. Wyeth submitted a New Drug Application (NDA) for MDD onDecember 22, 2005. The Company also has filed an NDA for vasomotorsymptoms (VMS) associated with menopause and ex...

Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder

...inical studies, duloxetine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine that is believed to potentiate the activity of thesechemicals in the central nervous system (brain and spinal cord).While the mechanism of action of duloxetine is not fully known,scientists believe its effects...

Wyeth Presents Phase 3 Data for Pristiq, an Investigational Non-Hormonal Therapy for Menopausal Hot Flashes and Night Sweats

...out Pristiq Pristiq is a serotonin-norepinephrine reuptake inhibitor (SNRI)being studied by Wyeth as a potential treatment for multipleindications, including moderate-to-severe menopausal hot flashesand night sweats. Pristiq is believed to work by affecting thebalance of serotonin and norepinephrine. These c...

Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain

...inical studies, duloxetine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine that is believed to potentiate the activity of thesechemicals in the central nervous system (brain and spinal cord).While the mechanism of action of duloxetine is not fully known,scientists believe its effect ...

In New Study, Duloxetine Reduced Non-specific Pain and Emotional Symptoms Associated with Depression

...ommonly referred to asserotonin and norepinephrine reuptake inhibitors (SNRIs), isapproved in more than 70 cou...inical studies, duloxetine is abalanced and potent reuptake inhibitor of serotonin andnorepinephrine/noradrenaline. While the mechanism of action ofduloxetine i...

Stanford Study Finds No Conclusive Benefit From Treating Kleptomania With Medication

...ass of antidepressants known asselective serotonin reuptake inhibitors, and earlier studies havesuggested that SSRIs can be effective in treating some impulsecontrol disorders, such as skin picking. In an earlier, non-blindedopen-label phase of the kleptomania study, when trial participantswere aware that the...