R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent
... wrist and hands were evaluated using Magnetic resonance
Imaging (MRI) and scored using the RAMRIS (Rheumatoid Arthritis Magnetic resonance
Imaging Scoring) system. Those results showed ... arthritis scoring system utilizing magnetic
imaging to evaluate abnormalities (synovitis, ...
MRI Emerges As Vital Resource in Treatment of Back Pain
ROSEMONT, Ill., Jan. 2 /PRNewswire-USNewswire/ -- Magnetic resonance
imaging (MRI) is a growing technology providing an increasing number of ... with the patient's clinical picture.
"The possibilities of magnetic resonance
have not yet been realized. It is a rapidly evolving field. When we need ...
ATL/TV1102 Trial Results Presented at World Congress on Treatment and Research in Multiple Sclerosis
... effectiveness in reducing MS-related brain
lesions as detected by magnetic resonance
images (MRI). The study met its
primary endpoint showing a significant ... injections over 8 weeks, and were monitored with
monthly MRI (magnetic resonance
imaging) brain scans during treatment, and
for the 8 weeks following ...
Repligen Receives FDA Fast Track Designation for RG1068 for Pancreatic Imaging
... to improve the assessment of pancreatic
duct structures by magnetic resonance
imaging (MRI). Fast track is a
process designed to facilitate the ... to improve the assessment of
pancreatic duct structures by magnetic resonance
imaging (MRI). The Phase 3
study is a multi-center, baseline-controlled, ...
BSGI Posts Higher Sensitivity than Mammography or MRI for the Detection of Ductal Carcinoma In Situ
... were detected with mammography, and 88
percent were detected with magnetic resonance
imaging. BSGI had the highest
sensitivity for the detection of DCIS, ... In Situ with Mammography, Breast Specific
Gamma Imaging, and Magnetic resonance
Imaging: A Comparative Study Academic
Radiology, Volume 14, No 8, August ...
VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE
... the use of a series of advanced and integrated in vitro assays, microscopic readouts, and in vivo imaging methodologies, including Magnetic resonance
(MR) imaging combined with quantitative Fluorescence Molecular Tomographic (FMT) imaging. Used together in a series of novel scientific models, the ...
Elbit Imaging Ltd. Announces - Swiss Team Uses InSightec's ExAblate(R) 4000 Brain System to Treat Patients With Functional Brain Disorders
... primarily in major
European cities; (iii) Image Guided Treatment - Investments in the research
and development, production and marketing of magnetic resonance
guided focused ultrasound treatment equipment; (vi) Residential Projects -
Initiation, construction and sale of residential projects and ...
Clay Walker's Band Against MS Foundation Donates $150,000 To Support Multiple Sclerosis Research
... Annual Clay Walker Charity Classic golf tournament at Pebble Beach. Wolinsky serves as director of the Multiple Sclerosis Research Group and Magnetic resonance
Imaging Analysis Center at the University of Texas Medical School. Including this gift, BAMS has provided the university with a total of $500,000 ...
Autism Studies Presented at Mid-Atlantic Research Consortium Meeting
... -- those without autism or other neurological disorders. Robert Schultz, Ph.D., director of the Center for Autism Research at CHOP, used magnetic resonance
imaging (MRI) and other imaging tools to study the "social brain," showing how children with ASDs and neurotypical children have contrasting patterns ...
Chronic Ankle Pain May Be More Than Just a Sprain
... of the ankle
Pain behind the anklebone
Pain that transmits from the ankle down into the foot
The use of magnetic resonance
imaging (MRI) or ultrasound can be helpful when identifying and diagnosing peroneal tendon injuries and disorders. "These imaging techniques offer a ...
Perceptive Informatics Introduces Medical Imaging Methodology to Accelerate Development Decisions About Alzheimer's Treatments
... faster development decisions about Alzheimer's treatments in development. To develop this method, the Perceptive Informatics team collected Magnetic resonance
Imaging (MRI) scans from the ADNI database using Perceptive's medical imaging system and regulatory compliant processes.
"It is more critical ...
Two-Year Phase III Data Presented at AAN 61st Annual Meeting Show Positive Outcome of Cladribine Tablets in Patients With Multiple Sclerosis
Sustained and statistically significant reductions in different types of brain lesions as measured by each of the pre-specified key magnetic resonance
imaging (MRI) secondary endpoints were shown and were consistent with clinical outcomes. Over the two year period of the study, both dose regimens of ...
Autism Genes Discovered; Help Shape Connections Among Brain Cells
... increases our understanding of how autism originates."
The gene discoveries, added Hakonarson, converge with evidence from functional magnetic resonance
imaging that children with ASDs may have reduced connectivity among neural cells, and with anatomy studies that have found abnormal development of ...
New Imaging Analysis Predicts Brain Tumor Survival
... would live longer, researchers from the University of Michigan Comprehensive Cancer Center have found.
The method uses a standard magnetic resonance
imaging, or MRI, protocol to monitor changes over time in tumor blood volume within individual voxels of the image, rather than a composite view of ...
VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial
... used pain as the primary endpoint. In the BST-CarGel(R) study, however, VirtualScopics is providing blinded data analysis of quantitative magnetic resonance
imaging (MRI) which will allow BioSyntech to demonstrate BST-CarGel's potential for affecting the quantity and quality of the repaired cartilage as ...
Research Shows VASER(R) Lipo Results in Excellent Skin Tightening
... worldwide using the VASER System. An alternative to traditional tumescent liposuction, the VASER - Vibration Amplification of Sound Energy at resonance
- Lipo System uses an advanced ultrasonic fat removal technology that has become a trusted method in a society saturated with fad procedures. ...
Rigel Expects R788 Partnership After Phase 2b Clinical Trials Results
... a 28-joint inspection), in addition to
various safety measures. TASKi3 will also include measurement of changes in
bone morphology using magnetic resonance
imaging (MRI) scans as a secondary
measure. In addition, Rigel will continue to develop R788 in various
lymphomas and is currently conducting a ...
Pieris Reports Development Progress for Anticalin(R) PRS-050, a Next Generation VEGF Antagonist
... the efficacy of the Anticalin(R)
product candidate in several preclinical models. Amongst those tested,
DCE-MRI (Dynamic Contrast-Enhanced Magnetic resonance
Imaging) has been
established and validated to monitor immediate treatment effects in the
upcoming Phase I clinical trial. Production process ...
Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults
... smoking nearly 6 marijuana joints daily in the final year before they stopped using the drug.
The study team performed a type of magnetic resonance
imaging scan called diffusion tensor imaging (DTI) that measures water movement through brain tissues. "The abnormal patterns of water diffusion that ...
Neuronetrix Announces Preliminary Alzheimer's Study Results at the Society for Neuroscience Conference
... a large international study sponsored by the US National
Institutes of Health (NIH).
The ADNI protocol uses psychometric testing, magnetic resonance
(MRI), and cerebrospinal fluid analysis (CSF) to accurately characterize
several aspects of Alzheimer's disease. Neuronetrix will use these ...
ASGE and The Pancreatic Cancer Action Network Partner to Raise Awareness About Pancreatic Cancer
... examination and some basic blood tests, most patients get scanned with a CT (computerized tomography) or "CAT" scan. CT scans and MRI (magnetic resonance
imaging) provide a detailed view of the pancreas and neighboring organs. A very important test, usually performed after a CT or MRI scan, is ...
New Insight Into the Controls on a Go-To Enzyme
To obtain that overall picture, St. Jude researchers used the analytical technique of X-ray crystallography, with help from nuclear magnetic resonance
(NMR) spectroscopy. In this widely used method of determining protein structure, researchers first crystallize a protein to be studied. Then, they ...
NCI Funded Clinical Trial to Study Treatment of Breast Cancer Using Cryoablation
... of this study.
The ACOSOG study protocol (designated as Z1072) will evaluate not only
cryoablation but also the ability of Magnetic resonance
Imaging (MRI) to
evaluate post-cryoablation efficacy in approximately 100 patients and 20
clinical sites. Patient enrollment into the study is ...
Good Samaritan Hospital Launches High Risk Breast Cancer Program at Good Samaritan North Health Center
... to monitor for any occurrence of breast or related
cancers. That may include more frequent clinical breast exams, ultrasound
exams or MRI (magnetic resonance
imaging) scans, along with digital
Linda Blum's Story of Survival
Linda Blum, 54, of Clayton, OH, is a woman who wanted answers about ...
Breast MRI Scan Could Determine Need for Radiation Therapy
... SEATTLE, Sept. 21 /PRNewswire/ -- For women whose breast cancer has
spread to their lymph nodes, a magnetic resonance
imaging (MRI) scan could
replace exploratory surgery as the method for determining whether those
women need radiation therapy to treat their disease, ...
Merck Serono Completes Enrollment in the REFLEX Trial of Rebif(R) in Patients at Risk of Developing Multiple Sclerosis
... developing MS due to a
recently experienced isolated demyelinating event (e.g. optic neuritis,
myelopathy or brainstem syndrome) and having magnetic resonance
(MRI) brain scans consistent with early signs of MS have been enrolled in
the REFLEX trial. Study participants were randomized in a 1:1:1 ...
Diverse Approaches to Alzheimer's Therapies Continue to Show Progress at ICAD
... 4 weeks or 400 mg once per week). Volunteers received a
single 100 mg dose of antibody. Safety assessments included brain imaging
using magnetic resonance
imaging (MRI) and examination of cerebrospinal
fluid (CSF, a fluid normally present around the brain and spinal cord). In
an optional sub-study, 24 ...
Bioheart Reports Promising Results From SDF-1 Modified MyoCell(R) Therapy in Heart Failure Study
... of rats, which suggest improved heart function, were recently
presented at two scientific meetings -- the International Society for
in Medicine (ISMRM) in Toronto, and the American Society
of Gene Therapy Meeting (ASGT) in Boston.
The data, presented by Bijoy Thattaliyath, MD, ...
Phase 1/2 Trial of Motexafin Gadolinium Plus Antibody Targeted Radiation Therapy Demonstrates High Complete Response Rate in Patients With Non-Hodgkin's Lymphoma
... to selectively concentrate in tumors
and induce apoptosis (programmed cell death). Its multifunctional mode of
action, including its magnetic resonance
imaging (MRI) detectability,
provides the opportunity for MGd to be used in a broad range of cancers. At
the 2007 American Society of Clinical ...
FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment
... equivalent to one relapse in five years, while 89% of patients were
free of the active brain lesions characteristic of MS as measured by
imaging (MRI) three years after starting treatment.
The results were presented at the 60th annual meeting of the American
Academy of Neurology ...
Halozyme Therapeutics Presents Pre-Clinical Studies of Systemic Delivery of Pegylated rHuPH20 Enyzme in Prostate Cancer Models at American Association for Cancer Research Conference
... enzyme. The dose dependent effects of systemic enzyme treatment
were evaluated by a combination of direct micropressure measurements,
imaging (MRI), ultrasound, immunohistochemistry, and
determination of tumor water content. A summary of findings is as follows:
-- Prostate ...
Evotec's EVT 101 Shown to Penetrate the Brain in Man and to Modulate Brain Activity During the Performance of Cognitive Tasks
... subjects and was conducted
at the Centre for Neuroimaging Sciences of the Institute of Psychiatry at
King's College London using functional magnetic resonance
techniques (fMRI) to investigate short-term effects of two doses of EVT 101
and placebo. The effects of the compound on cognitive endpoints, ...
Pixantrone to be Studied in Phase I/II Trial for Aggressive Multiple Sclerosis
... an immunosuppressive agent based on its ability to decrease
the lymphocyte count and to evaluate efficacy in MS based on gadolinium
enhanced magnetic resonance
imaging. This trial is an open-label,
multi-center, non-comparative study of pixantrone administered at a dose of
120 mg/m2 once every 21 days (3 ...
New Clinical Data Further Supports Chromium Picolinate's Role in Enhancing Brain Activity in Older Adults
... a 12-week period might affect
brain activation under working memory task demands in 13 older adults with
early memory decline. Functional magnetic resonance
imaging (fMRI) scans
were performed while study participants worked on a challenging cognitive
task that involved holding in mind and manipulating ...
DATATRAK and COResearch to Collaborate on Six Cardiac Safety Projects
... imaging services to include: echocardiography, atherosclerotic
imaging-carotid intima-media thickness, cardiac nuclear imaging, cardiac
imaging, quantitative coronary angiography, and cardiac
DATATRAK International, Inc. is a worldwide technology company ...
PTC Therapeutics Presents Encouraging Phase 1 Results of its Novel VEGF Inhibitor, PTC299, at 30th Annual San Antonio Breast Cancer Symposium
... and prolonged time to tumor progression in hormone-
sensitive and -insensitive xenograft models. As assessed by dynamic
contrast- enhanced magnetic resonance
imaging (DCE-MRI), PTC299 also
significantly reduced xenograft tumor volume and tumor perfusion, with
effects beginning within one day of treatment ...
Cleveland Clinic Leading Clinical Program to Improve Early-Stage Lung Cancer Detection
... any additional action by -- or involvement of -- the patient; CAD
is applied by the radiologist after the chest X-ray is taken. CT scans or
imaging (MRI) are effective diagnostic follow-up methods
for chest X-rays that have suspicious findings.
In previous clinical trials, Riverain's ...
Siemens Showcases Its Most Comprehensive and Advanced Breast Care Portfolio
... and improved patient outcomes.
With the movement toward a multimodality approach to breast care, imaging
technologies such as ultrasound and magnetic resonance
imaging (MRI) are
playing an increasing role in all stages of breast care. At RSNA, Siemens
is showcasing its latest advancements in breast ...
Retrospective Analysis Finds That Initiation of Insulin Glargine in Patients With Type 2 Diabetes was Associated With a Lower Incidence Rate of Myocardial Infarction as Compared With NPH Insulin
... of this broad effort, the INTENSIVE (Intensive Insulin Therapy
and Size of Infarct as a Validated Endpoint by Cardiac MRI) trial will use
imaging to compare the effects of tight glycemic control
using insulin glargine and insulin glulisine to usual care on cardiac
function (infarction ...
ActivBiotics to Present Results of Pivotal Study in the Treatment of Peripheral Arterial Disease at AHA Meeting
... of atherosclerosis and
image-detectable carotid disease. This study will use the non-invasive
imaging techniques of combined high-resolution magnetic resonance
and ultrasound to assess the degree of architectural changes in the carotid
artery brought about by rifalazil treatment. The presence and ...