Rectal in Medical Technology

Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets

... symptoms, including number of bowel movements and rectal bleeding, for some as early as three weeks. ... of four of patients by six weeks and decreased rectal bleeding for approximately 80 percent of patients ... of moderately active UC, Asacol HD helped reduce rectal bleeding and stool frequency, without the use of ...

Archimedes Pharma Announces Successful Proof-of-Concept Results on Two Intranasal Development Projects

... to commercially available intravenous (IV) and rectal formulations (2 mg and 5 mg doses respectively). ... bioavailability compared to the commercial rectal formulation, with maximum plasma concentrations ... the potential of IN Diazepam to replace IV and rectal products. Diazepam, a long established ...

Safety and Efficacy Results Presented From Largest Prospective Controlled Clinical Study of Ulcerative Colitis

... have been previously treated with steroids and/or rectal therapies, received benefit from ... was determined by clinical assessments of rectal bleeding, stool frequency, and sigmoidoscopy. ... (which was based on the clinical assessments of rectal bleeding, stool frequency, and sigmoidoscopy) and ...

New Analysis Shows Efficacy of REMICADE(R) in Treatment of Ulcerative Colitis in Patients with Recent Disease Onset or Long-Standing Disease

... three points, accompanied by a decrease in the rectal bleeding subscore of at least one or a rectal bleeding subscore of 0 or 1, and clinical ... patients in clinical remission will have a rectal bleeding subscore of 0 or 1. The ACT 1 and ACT ...

Analysis of Ulcerative Colitis (UC) Time to Symptom Resolution Data from Pivotal Study of LIALDA(TM) (mesalamine) Presented at DDW

... resolution. Initial symptom resolution of rectal bleeding, normalization of stool frequency or ... Resolution of symptoms was defined for both rectal bleeding and stool frequency as a modified UC-DAI ... arm only. -- Symptom resolution of rectal bleeding at the first day and first of ...

Over 30 New Studies of Oral Xeloda(R) Featured at the 2008 Gastrointestinal Cancers Symposium

... against those of 5-FU-based regimens in colon and rectal cancer. The fifth U.S. abstract highlights ... in the treatment of patients with colon or rectal cancer (CRC) (Presenter: Edward Chu) -- Jan. 27, ... Capecitabine use in patients with colon and rectal cancer (CRC): A claims database analysis of ...

Study Data Show Asacol(R) (Mesalamine) is Effective in Treating All Extents of Ulcerative Colitis Including Isolated Proctitis

... weeks 83 percent of patients had improvement in rectal bleeding, 75 percent had mucosal healing and 57 ... and a baseline score in either or both the rectal bleeding and stool frequency clinical assessments ... scale, 0-3). Patients were prohibited from taking rectal therapies and were only treated with Asacol. ...

New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients

... of three consecutive days of resolution of both rectal bleeding and increased stool frequency. The time ... was defined as resolution (score=0) of both rectal bleeding (RB) and stool frequency (SF). ... people experience symptoms such as diarrhea, rectal bleeding, abdominal cramping and an urgent need ...

New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG

... of less than or equal to 1 with scores of 0 for rectal bleeding and stool frequency, a combined ... resolution of symptoms (stool frequency and rectal bleeding) was 25, 26 and 44 days, in the LIALDA ... analysis included both stool frequency and rectal bleeding when determining the median time ...

Task Force Says Men Age 75 and Older Should Not Be Screened For Prostate Cancer

... for prostate cancer is most often performed using PSA tests and digital rectal exams. The PSA test is more likely to detect prostate cancer than the digital rectal exam. However, prostate cancers that are found with a PSA test take years ...

First Skin Cancer Patients Treated With Electronic Brachytherapy (eBx) At University of Wisconsin Riverview Cancer Center

... alternatives for radioactive medical isotopes. Commercially available for treatment of early stage breast cancer, skin cancer, and endometrial and rectal indications, the Axxent(R) Electronic Brachytherapy System is also cleared for use in the treatment of other cancers or conditions where radiation ...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

... or diet and other environmental factors. Symptoms of Crohn's disease can vary but often include abdominal pain and tenderness, frequent diarrhea, rectal bleeding, weight loss and fever. There is currently no cure for Crohn's disease. About REMICADE REMICADE was the first anti-TNF-alpha ...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... cancer diagnosed in the United States. It is estimated that 106,100 people will be diagnosed with colon cancer, 40,870 people will be diagnosed with rectal cancer and approximately 50,000 deaths will be attributable to some form of colorectal cancer in 2009. Surgery is often the main treatment for early ...

TNFerade(TM) Phase III Data Presented at ASCO

... TNFerade has also been and is currently being evaluated for its potential use in the treatment of several other cancers, including esophageal cancer, rectal cancer, and head and neck cancer. GenVec also uses its proprietary adenovector technology to develop vaccines for infectious diseases including HIV, ...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... cancer diagnosed in the United States. It is estimated that 106,100 people will be diagnosed with colon cancer, 40,870 people will be diagnosed with rectal cancer and approximately 50,000 deaths will be attributable to some form of colorectal cancer in 2009. Surgery is often the main treatment for early ...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

... cancer in both American men and women, and the third leading cause of cancer death in the U.S. In 2008, an estimated 148,810 new cases of colon and rectal cancer were expected to be diagnosed in the U.S., with an estimated 49,960 deaths.(1) A FOLFOX-containing regimen is the current standard of care but ...

Stand Up To Cancer Awards $73.6 Million for Novel, Groundbreaking Cancer Research

... in adults and children across ethnicities including, but not limited to pancreatic, breast, ovarian, cervical, uterine, brain, lung, prostate, rectal and colon, which represent two thirds of all U.S. cancer deaths. (562,340 people are expected to die of cancer in the United States this year.) In ...

Poniard Pharmaceuticals Reports First Quarter 2009 Financial Results and Provides a Corporate Update

... cancer in both American men and women, and the third leading cause of cancer death in the U.S. In 2008, an estimated 148,810 new cases of colon and rectal cancer were expected to be diagnosed in the U.S., with an estimated 49,960 deaths (American Cancer Society, Cancer Facts and Figures 2009). The ...

Poniard Pharmaceuticals to Present New Data from Phase 2 Clinical Trials of Picoplatin in Multiple Tumor Types at the 45th Annual Meeting of the American Society of Clinical Oncology

... cancer in both American men and women, and the third leading cause of cancer death in the U.S. In 2009, an estimated 148,810 new cases of colon and rectal cancer were expected to be diagnosed in the U.S., with an estimated 49,960 deaths (American Cancer Society, Cancer Facts and Figures 2009). The ...

A Joint Statement From America's Prostate Cancer Advocacy, Education, and Support Organizations

... the possibility of a prostate cancer-specific survival benefit associated with the regular use of prostate specific antigen (PSA) testing and digital rectal examination (DRE). * These studies provide no convincing evidence that mass screening of men over 50 or 55 years of age will lead to a prostate ...

Leader in Prostate Health Urges Prostate Cancer Screening in Face of Contradicting Data

... a biopsy and subsequent treatment if cancer is found. The organization recommends a baseline prostate health assessment, including PSA and digital rectal exam (DRE), for all men at 40 years of age and at 35 for men at high risk (including those with a family history of prostate cancer and ...

Walter Reed Army Medical Center offers HIFU for Qualifying Men with Locally Recurrent Prostate Cancer in a Phase III Clinical Trial

... frequency, urgency, mild discomfort while urinating. Less common side effects may include urinary stricture, retention, incontinence, impotence and rectal fistula. For more information about enrolling in HIFU trials, please call: 1-877-874-4389 or visit www.ProstateCancerRecurrentTrial.org . ...

Cardium's InnerCool Announces Positive Benefits of Cooling During Robotic-Assisted Prostate Surgery Published in Urology

... UroCool(TM) catheter is expected to be submitted in the first quarter of 2009. The UroCool(TM) catheter is designed to be placed within the rectal cavity adjacent to the prostate during surgery and is used in conjunction with InnerCool's Celsius Control System(TM) which circulates cold saline in ...

Takeda Initiates Two Phase III Studies with Vedolizumab (MLN0002) in Patients with Inflammatory Bowel Disease

... relapsing-remitting conditions, caused by an overactive inflammatory response in the gastrointestinal tract. Common symptoms include diarrhea, rectal bleeding, incontinence, abdominal pain, fever, malaise and weight loss. About Takeda Pharmaceutical Company Limited Located in Osaka, ...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

... the main safety parameter. In this study, 1,166 patients with advanced lung (279), colon (235), breast (165), ovarian (143), stomach (98), rectal (87), pancreatic (53), head and neck (36), and other cancers (54) were randomized to one of two treatment arms: once-daily subcutaneous injections of ...

GenVec Announces Multiple Presentations at the American Society of Tropical Medicine and Hygiene Meeting

... TNFerade(TM), is currently in a pivotal clinical study (PACT) in locally advanced pancreatic cancer. Additional clinical trials are in progress in rectal cancer, head and neck cancer, and melanoma. GenVec also uses its proprietary adenovector technology to develop vaccines for infectious diseases ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

... or diet and other environmental factors. Symptoms of Crohn's disease can vary but often include abdominal pain and tenderness, frequent diarrhea, rectal bleeding, weight loss and fever. There is currently no cure for Crohn's disease. About REMICADE REMICADE is the global market leader among ...

Electronic Brachytherapy a Viable Option for Early Stage Breast Cancer, According to Study Presented at ASCO Breast Cancer Symposium

... seek alternatives for radioactive medical isotopes. Commercially available for accelerated treatment of early stage breast cancer and endometrial and rectal indications, the Axxent(R) Electronic Brachytherapy System is also cleared for use in the treatment of other cancers or conditions where radiation ...

August 2008 Mayo Clinic Women's HealthSource Highlights Avoiding Blood Pressure Increase at Menopause, Healthful Benefits of Dark Chocolate and Scheduling a Colorectal Exam

... aren't getting tested regularly. Many have never been screened. Colon cancer occurs in the large intestine, the lower part of the digestive system. rectal cancer involves the last six inches of the colon. Cancer that begins in either organ may be called colorectal or colon cancer. For people age 50 and ...

First Breast Cancer Patient Receives Treatment in National Electronic Brachytherapy Registry Launched by Three Physician Societies

... and Vanderbilt University. About Electronic Brachytherapy Cleared for accelerated treatment of early stage breast cancer and endometrial and rectal indications, the Axxent(R) Electronic Brachytherapy System is now cleared for use in the treatment of other cancers or conditions where radiation ...

Prostate Cancer Treatment Offers Results Without Side Effects

... that deliver a time-release dose of radiation. Side effects of these treatments often leave a man with impotence, incontinence, fatigue, hot flashes, rectal irritation or damage, diarrhea and blood in the stool. At least 40% of all surgery patients will experience erectile dysfunction. Side effects may ...

Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission

... onset typically before age 40. Common symptoms of the disease include diarrhea, cramping, abdominal pain, weight loss, fever, and in some cases, rectal bleeding. Over the course of their disease, up to 75 percent of patients with Crohn's will undergo surgery for complications or disease resistant to ...

AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis

... The Mayo score looks at stool frequency, rectal bleeding, findings of flexible ... one other clinical assessment (stool frequency, rectal bleeding, patient's functional ... of stool frequency (normal stool frequency), rectal bleeding (no rectal bleeding), patient's ...

Salix Pharmaceuticals Announces Positive Top Line Results of Balsalazide Tablets Registration Study

... Activity Index of greater than or equal to 3 points with improvement in rectal bleeding) as well as the following key secondary efficacy endpoints (clinical remission, mucosal healing, improvement of rectal bleeding and improvement in physician global assessment.) These pivotal ...

GenVec Announces New Research at AACR on Selectivity and Mechanism of Action of TNF-Based Anti-Cancer Therapy

... product, TNFerade(TM) is currently in a pivotal Phase II/III study (PACT) in locally advanced pancreatic cancer; Phase II studies are in progress in rectal cancer and melanoma; and Phase I/II studies are in progress in head and neck cancer. GenVec also uses its proprietary adenovector technology to ...

Final Vectibix Positive Pivotal Phase 3 Trial Results In Metastatic Colorectal Cancer Patients Published

... in men and in women in the United States. The American Cancer Society estimated that about 112,340 new cases of colon cancer and 41,420 new cases of rectal cancer will be diagnosed in 2007. Colorectal cancer is the second leading cause of cancer death among men and women in the United States and Canada ...

GenVec Presents Research on New Ad35 Adenovector at ARVO

... product, TNFerade(TM) is currently in a pivotal Phase II/III study (PACT) in locally advanced pancreatic cancer; Phase II studies are in progress in rectal cancer and melanoma; and Phase I/II studies are in progress in head and neck cancer. GenVec also uses its proprietary adenovector technology to ...

Salix Pharmaceuticals Previews Digestive Disease Week 2007

... The most common side effects (vs. placebo) were flatulence 11.3% (vs. 19.7%), headache 9.7% (vs. 9.2%), abdominal pain 7.2% (vs. 10.1 %) and rectal tenesmus 7.2% (vs. 8.8%). MOVIPREP(R) (PEG 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for ...

Analysis of Ulcerative Colitis (UC) Remission Rates from Long-term Safety Study of Lialda (mesalamine) Presented at DDW

... stringent clinical and endoscopic criteria: modified UC Disease Activity Index (UC-DAI) score of less than or equal to 1, with scores of 0 for rectal bleeding and stool frequency, a combined Physician's Global Assessment and sigmoidoscopy score of less than or equal to 1, with a sigmoidoscopy score ...