Probes in Medical Technology

Getting More From Whole-Transcript Microarrays

... on various factors, including the number of probes covering the gene and the nature of the splicing ... uses information about adjacent poorly fitting probes to calculate differential expression in the Gene ... few exons, since for these genes the coverage of probes in the Gene platform can be greater than the Exon ...

Southern Research Institute Wins $14.7 Million NIH Award to Participate in Molecular Libraries Probe Production Center Network

... viruses. Therefore, identifying new molecular probes will promote the discovery of new approaches for ... emphasizing the generation of high quality probes and biological-chemical data for high-value ... goal of the MLP is to develop new small molecule probes that will be used as research tools with the ...

WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center

... Utilizing the da Vinci Surgical System, a laparoscopic camera and robotic probes are inserted into the patient through several small incisions. Pencil-sized probes translate the surgeon's hand movements and adjust themselves to compensate ...

Freezing Kidney Cancer: Hot Treatment Should Be New Gold Standard for Destroying Small Tumors

... interventional cryoablation, which uses imaging to pinpoint tumors and probes to penetrate the skin to deliver freezing cold directly to a diseased ... Using computed tomography (CT) imaging, researchers could view tumors and probes in real time. Interventional cryoablation "has an excellent safety ...

Study Shows Use of AdvanDx's PNA FISH(TM) Test was Associated with an 82% Reduction in Intensive Care Unit Mortality Rates from Staphylococcus aureus Bloodstream Infections

... in situ hybridization (FISH) assay that uses PNA (peptide nucleic acid) probes to target species specific ribosomal RNA (rRNA) in live bacteria and yeast. The unique properties of the non-charged, peptide backbone of PNA probes enable the use of FISH assays in exceedingly complex sample matrixes, such ...

BioView Reports Interim Results of Early Detection Lung Cancer Diagnostic Test

... 1) 4. Advanced stage lung cancer patients The sputum samples were blindly scanned and analyzed morphologically and genetically, with fluorescent probes exclusively licensed to BioView, on BioView's automated Duet scanning station by Company personnel. The results of the test were classified as ...

CRi Announces New Maestro(TM) EX In Vivo Imaging System with Improved Performance and an Affordable Price

... James Mansfield, Director of Multispectral Imaging Systems at CRi. The Maestro EX enables more precise detection and quantitation of molecular probes in live animals and complements the automated high-throughput Maestro 2 imaging system, by providing comparable imaging performance in a design ...

Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists

... the harder it is to treat and the further it can spread." Narayanan and Peterson have analyzed DNA of hundreds of pathogens and synthesized DNA probes for the specific genetic sequences that set each pathogen apart. So far they can detect as many as 557 genes, making it possible for them to screen ...

AdvanDx Submits Yeast Traffic Light PNA FISH(TM) for FDA 510(k) Clearance for Detection of Candida species in Positive Blood Cultures

... PNA FISH is an easy-to-use and highly sensitive and specific fluorescence in situ hybridization (FISH) assay that uses PNA (peptide nucleic acid) probes to target species specific ribosomal RNA (rRNA) in bacteria and yeast. PNA FISH tests enable microbiology labs to provide rapid and accurate ...

ATS Medical Announces Initial Clinical Results of Stand-Alone Atrial Fibrillation Procedures Using ATS CryoMaze Product Line

... rhythm and only five of these patients were using antiarrhythmic medication. Dr. Rodriguez said, "Stand-alone ablation using the ATS cryoablation probes is a reliable method of replicating the complete Maze procedure, with initial success rates that are similar to Dr. Cox's original procedure, which ...

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

... a proprietary suite of DNA microarrays, consumables, instruments, and services. Roche NimbleGen uniquely produces high-density arrays of long oligo probes that provide greater information content and higher data quality necessary for studying the full diversity of genomic and epigenomic variation. The ...

Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.

... on a small, coated quartz surface. Different probes can be attached to different locations. Each ... test, this provides the ability for particular probes to bind portions of wild-type or mutant sequences ... on the scan, which indicates the particular probes bound by the patients DNA sample. The software ...

The Past, Present and Future of HLA Typing

... labeled, sequence specific oligonucleotide probes to HLA loci amplified by the polymerase chain ... sequence specific oligonucleotide probes. These probes would bind only to complementary HLA DNA ... nucleotide differences consistently. Several probes could be used to identify an array of HLA ....

Testing for Human Papillomavirus

... and high risk types. The HC2 assays utilize cocktails of specific RNA probes that are directed toward target HPV DNA sequences. An antibody to DNA-RNA ... on histology or LBPT slides that are incubated with fluorescein-tagged DNA probes and counterstained. Microscopic observation of specifically stained ...

New Advances in Gastric Diagnostics: Smaller is Better

... Instead, Endoscopic Ultrasound (EUS) consists of miniaturized ultrasound probes that can be fit into the tip of endoscopic equipment. EUS allows highly ... EUS Exera series, high-frequency/high-resolution miniaturized ultrasound probes that are contained within a modified endocope (ultrasonic ...

Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

... media. IDI-MRSA (Infectio Diagnostic, Inc.), utilizes PCR for the amplification of MRSA DNA and fluorogenic target-specific hybridization probes for the detection of the amplicons. Nasal swab specimens are placed directly in sample preparation buffer, and after additional processing, an ...

Genetic Analysis Systems Enter the Clinical Mainstream

... assay, the only FDA cleared product to test for prenatal aneuploidy. Vysis offers an expansive line of DNA FISH (fluorescence in situ hybridization) probes for evaluation of chromosome anomalies in preimplantation, prenatal and postnatal genetic testing and research. The availability of genetic ...